Microbes In Indian Buffalo Rumen A Metagenomics Approach

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Microbes in Indian Buffalo Rumen: A Metagenomics Approach

Author : Prof. Dr. Nirmal Kumar, J.I.
Publisher : Google Book Publishers
ISBN 13 :
Total Pages : 206 pages
Book Rating : 4./5 ( download)

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Book Synopsis Microbes in Indian Buffalo Rumen: A Metagenomics Approach by : Prof. Dr. Nirmal Kumar, J.I.

Download or read book Microbes in Indian Buffalo Rumen: A Metagenomics Approach written by Prof. Dr. Nirmal Kumar, J.I. and published by Google Book Publishers. This book was released on with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present book Microbes in Indian Buffalo Rumen: A Metagenomics Approach will be useful to researchers, who are engaged in research on DNA sequencing of Microbes with diet composition, gut flora, ruminal microbes, and microbial community dynamics of cattle. The book covers not only the rumen metagenomics, but also highlights the salient findings about specifically exploring the microbial community dynamics from Mehsani and Kankrej breeds of buffaloes at different diet treatments, comparing the rumen microbiota at each diet treatments, and identifying the methanogens and their enzymes responsible for methanogenesis at each dietary treatment. The rumen microbiota studied under the different diet treatments consisted of 48 metagenomes per animal species, outputted a huge sequence dataset, the rarefaction analysis of which confirmed the rumen metagenomes were sequenced to sufficient depths. Though Bacteroidetes and Firmicutes appeared as a key role player in the constitution of the ruminal environment, the significant shift in the abundance of the rest minor phyla confirms their auxiliary role in metabolizing of the fibre-rich feed particles. The more occurrences of Clostridium, Ruminococcus and Eubacterium coming from Firmicutes group, in solid fraction as compared to liquid fraction provides the hint of their foremost site of metabolic action, a fibre, where they actively participate in fibre degradation and produces oligo- and di-saccharides (soluble) for further utilization by Bacteroidetes in liquid fraction. Metabolic subsystems shows predominance of carbohydrate utilization among rest of the subsystems provides and thus provides the insights in functional capability of the ruminal microbiota for the degradation of the ingested food and hence aid in endowment of the nutrition to the host. Further, the results of CAZyme families conceived a fact that in Mehsani buffalo, the green roughage showed more abundance of GH2 genes (β-galactosidase) and dry roughage showed more abundance of GH3 genes (exo acting β-glucosidase). Thereby confirming efficient cellulosic biomass degradation in dry roughage as compared to green roughage, where more hydrolysis of lactose as well as the transgalactosylation of galacto-oligosaccharides takes place. Apart from that, the taxonomic assignment of the CAZymecontigs in Kankrej cattle revealed that carbohydrate esterases (CE) are group of the enzymes that majorly contributed by Prevotella, Bacteroides and Parabacteroides, on the other hand, glycosyl hydrolase 3 (GH3), a CAZy family, contributed by Clostridium and Fibrobacter in liquid portion and Clostridium, Eubacterium and Ruminococcus in solid fraction. Moreover, the present book will be very much benefited to all young as well as professional researchers and scientists of India and world over, covering wide regional, national, continental, and global spectrum.

Functional Metagenomics: Tools and Applications

Author : Trevor C. Charles
Publisher : Springer
ISBN 13 : 3319615106
Total Pages : 256 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Functional Metagenomics: Tools and Applications by : Trevor C. Charles

Download or read book Functional Metagenomics: Tools and Applications written by Trevor C. Charles and published by Springer. This book was released on 2017-10-09 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, the latest tools available for functional metagenomics research are described.This research enables scientists to directly access the genomes from diverse microbial genomes at one time and study these “metagenomes”. Using the modern tools of genome sequencing and cloning, researchers have now been able to harness this astounding metagenomic diversity to understand and exploit the diverse functions of microorganisms. Leading scientists from around the world demonstrate how these approaches have been applied in many different settings, including aquatic and terrestrial habitats, microbiomes, and many more environments. This is a highly informative and carefully presented book, providing microbiologists with a summary of the latest functional metagenomics literature on all specific habitats.

Rumen Microbiology: From Evolution to Revolution

Author : Anil Kumar Puniya
Publisher : Springer
ISBN 13 : 8132224019
Total Pages : 380 pages
Book Rating : 4.1/5 (322 download)

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Book Synopsis Rumen Microbiology: From Evolution to Revolution by : Anil Kumar Puniya

Download or read book Rumen Microbiology: From Evolution to Revolution written by Anil Kumar Puniya and published by Springer. This book was released on 2015-07-11 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers an in-depth description of different groups of microbes (i.e. bacteria, protozoa, fungi and viruses) that exist in the rumen microbial community, and offers an overview of rumen microbiology, the rumen microbial ecosystem of domesticated ruminants, and rumen microbial diversity. It provides the latest concepts on rumen microbiology for scholars, researchers and teachers of animal and veterinary sciences. With this goal in mind, throughout the text we focus on specific areas related to the biology and complex interactions of the microbes in rumen, integrating significant key issues in each respective area. We also discuss rumen manipulation with plant secondary metabolites, microbial feed additives, utilization of organic acids, selective inhibition of harmful rumen microbes, and ‘omics’ approaches to manipulating rumen microbial functions. A section on the exploration and exploitation of rumen microbes addresses topics including the current state of knowledge on rumen metagenomics, rumen: an underutilized niche for industrially important enzymes and ruminal fermentations to produce fuels. We next turn our attention to commercial applications of rumen microbial enzymes and to the molecular characterization of euryarcheal communities within an anaerobic digester. A section on intestinal disorders and rumen microbes covers acidosis in cattle, urea/ ammonia metabolism in the rumen and nitrate/ nitrite toxicity in ruminant diets. Last, the future prospects of rumen microbiology are examined, based on the latest developments in this area. In summary, the book offers a highly systematic collection of essential content on rumen microbiology.

Gastrointestinal Microbiology

Author : Roderick Mackie
Publisher : Springer Science & Business Media
ISBN 13 : 1461541115
Total Pages : 667 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Gastrointestinal Microbiology by : Roderick Mackie

Download or read book Gastrointestinal Microbiology written by Roderick Mackie and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 667 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extremely diverse and complicated bacterial and protozoan populations inhabit the rumen and intestinal tract of animals, and there is a delicate balance among the individual populations within this complex microbial community. This authoritative edited volume, the first in a two-volume set, reviews the gut environment and the fermentations taking place in animal digestive tracts. It is an essential source of reference for microbial ecologists and physiologists, medical microbiologists and gastroenterologists, biochemists, nutritionists, veterinarians and animal scientists, and wildlife ecologists.

Metagenomics

Author : Muniyandi Nagarajan
Publisher : Academic Press
ISBN 13 : 0128134038
Total Pages : 400 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Metagenomics by : Muniyandi Nagarajan

Download or read book Metagenomics written by Muniyandi Nagarajan and published by Academic Press. This book was released on 2017-10-29 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metagenomics: Perspectives, Methods, and Applications provides thorough coverage of the growing field of metagenomics. A diverse range of chapters from international experts offer an introduction to the field and examine methods for metagenomic analysis of microbiota, metagenomic computational tools, and recent metagenomic studies in various environments. The emphasis on application makes this text particularly useful for applied researchers, practitioners, clinicians and students seeking to employ metagenomic approaches to advance knowledge in the biomedical and life sciences. Case-study based application chapters examine topics ranging from viral metagenome profiling, metagenomics in oral disease and health, metagenomic insights into the human gut microbiome and metabolic syndromes, and more. Additionally, perspectives on future potential at the end of each chapter provoke new thought and motivations for continued study in this exciting and fruitful research area. - Provides thorough coverage of the rapidly growing field of metagenomics, with an emphasis on applications of relevance to translational researchers, practitioners, clinicians and students - Features a diverse range of chapters from international experts that offer an introduction to the field and examine methods for metagenomic analysis of microbiota, metagenomic computational tools and research pipelines - Highlights perspectives on future potential at the end of each chapter to provoke new thought and motivations for continued study in this exciting and fruitful research area

Manual of Environmental Microbiology

Author : Cindy H. Nakatsu
Publisher : John Wiley & Sons
ISBN 13 : 155581882X
Total Pages : 1042 pages
Book Rating : 4.5/5 (558 download)

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Book Synopsis Manual of Environmental Microbiology by : Cindy H. Nakatsu

Download or read book Manual of Environmental Microbiology written by Cindy H. Nakatsu and published by John Wiley & Sons. This book was released on 2020-08-11 with total page 1042 pages. Available in PDF, EPUB and Kindle. Book excerpt: The single most comprehensive resource for environmental microbiology Environmental microbiology, the study of the roles that microbes play in all planetary environments, is one of the most important areas of scientific research. The Manual of Environmental Microbiology, Fourth Edition, provides comprehensive coverage of this critical and growing field. Thoroughly updated and revised, the Manual is the definitive reference for information on microbes in air, water, and soil and their impact on human health and welfare. Written in accessible, clear prose, the manual covers four broad areas: general methodologies, environmental public health microbiology, microbial ecology, and biodegradation and biotransformation. This wealth of information is divided into 18 sections each containing chapters written by acknowledged topical experts from the international community. Specifically, this new edition of the Manual Contains completely new sections covering microbial risk assessment, quality control, and microbial source tracking Incorporates a summary of the latest methodologies used to study microorganisms in various environments Synthesizes the latest information on the assessment of microbial presence and microbial activity in natural and artificial environments The Manual of Environmental Microbiology is an essential reference for environmental microbiologists, microbial ecologists, and environmental engineers, as well as those interested in human diseases, water and wastewater treatment, and biotechnology.

Applications of Biotechnology for Sustainable Development

Author : Kunal Mukhopadhyay
Publisher : Springer
ISBN 13 : 9811055386
Total Pages : 208 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Applications of Biotechnology for Sustainable Development by : Kunal Mukhopadhyay

Download or read book Applications of Biotechnology for Sustainable Development written by Kunal Mukhopadhyay and published by Springer. This book was released on 2017-10-06 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses different bioprocesses to produce value-added compounds, the science behind their production, the economics of their introduction to the marketplace, their environmental impacts, and their implications for world agriculture. It also provides insights into various technologies and protocols used. The major strength of biotechnology is its multidisciplinary nature and broad range of scientific approaches. Recent advances in various biotechnological fields are facilitating the production of fine chemicals, recombinant proteins, biomaterials and pharmaceuticals. Biotechnology plays an important role, especially in the fields of food production, renewable raw materials and energy, pollution prevention and bioremediation. Biotechnology’s greatest contribution is in agriculture – in making crops more efficient. Resource recovery, recycling and hazardous-waste disposal are other environmentally beneficial facets of biotechnology. Thus, biotechnology is a pivotal tool for sustainable development, which has become a priority for the world’s policy makers. The concept of sustainable development is based on the goal of increasing the basic standard of living of the world’s growing population, without depleting finite natural resources and degrading the environment. Emerging biotechnologies offer novel approaches with the potential to achieve the goal of sustainability and striking a balance between developmental needs and environmental conservation.

Understanding Host-Microbiome Interactions - An Omics Approach

Author : Ravindra Pal Singh
Publisher : Springer
ISBN 13 : 9811050503
Total Pages : 367 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Understanding Host-Microbiome Interactions - An Omics Approach by : Ravindra Pal Singh

Download or read book Understanding Host-Microbiome Interactions - An Omics Approach written by Ravindra Pal Singh and published by Springer. This book was released on 2017-09-01 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers up-to-date information on different microbiomes, their community composition and interactive functions with the host, bringing together information from diverse research reports to provide an overview of the rapid developments in meta-omics technologies. It is a valuable resource for scientists, researchers, postgraduate and graduate students interested in understanding the impact and importance of next generation sequencing technologies on different hosts and their microbiomes.

Microbial Genomics in Sustainable Agroecosystems

Author : Vijay Tripathi
Publisher : Springer Nature
ISBN 13 : 9811387397
Total Pages : 293 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis Microbial Genomics in Sustainable Agroecosystems by : Vijay Tripathi

Download or read book Microbial Genomics in Sustainable Agroecosystems written by Vijay Tripathi and published by Springer Nature. This book was released on 2019-11-05 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent decades, significant advances in new methodologies like DNA sequencing and high-throughput sequencing have been used to identify microorganisms and monitor their interactions with different environments. Microbial genomics techniques are opening new approaches to microbiology by revealing how microorganisms affect human beings and the environment. This book covers four major areas: 1) Environmental microbial genomics, 2) Microbial genomics in human health, 3) Microbial genomics in crop improvement and plant health protection, and 4) Genome analysis of microbial pathogens. Within these areas, the topics addressed include: microbial genome diversity, evolution, and microbial genome sequencing; bioinformatics and microarray-based genomic technologies; functional genomics of bioremediation of soil and water from organic and inorganic pollutants and carbon management; functional genomics of microbial pathogens and relevant microorganisms; functional genomics of model microorganisms; and applied functional genomics. Given its scope, the book offers a comprehensive source of information on the latest applications of microorganisms and microbial genomics to enhance the sustainability of agriculture and the environment.

Genomic, Proteomics, and Biotechnology

Author : RC Sobti
Publisher : CRC Press
ISBN 13 : 1000782565
Total Pages : 420 pages
Book Rating : 4.0/5 (7 download)

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Book Synopsis Genomic, Proteomics, and Biotechnology by : RC Sobti

Download or read book Genomic, Proteomics, and Biotechnology written by RC Sobti and published by CRC Press. This book was released on 2022-12-29 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: High-throughput molecular technologies ("omics") can help to decipher the contributions of different physiological systems and identify candidate molecules that are representative of different physiological pathways thereby allowing the discovery of biomarkers. Notably, the omics technologies along with and computational methods, bioprospecting, and artificial intelligence will continue to lead to better understanding of biological mechanisms that are responsible for physical attributes, or phenotypes. Research breakthroughs obtained through these technologies can be used to enhance productivity of food animals, meet the increasing demand for animal-sourced foods, enhance high-quality nutrient availability, ensure nutrient safety, mitigate the effects of climate variability, and result in new technologies that provide continued improvement in food security worldwide. Such breakthroughs are an urgent necessity because over the past 50 years, there has been an unprecedented increase in the world’s population, which will reach ten billion by the year 2050. Innovative and technological advancements that enhance all aspects of food production will arise from basic, fundamental research. Besides food, animal by-products have found many applications in the fields of pharmaceuticals, cosmetics, and household and industrial products. Hence, the need to ameliorate the productivity, reproductivity, growth performance, and disease resistance in animals has created a worldwide interest in gaining a deeper understanding of animal biology, biotechnology and genomics, and proteomics. The present volume thoroughly discusses the omics studies in domestic and non-domestic animals and their role in mitigation of various challenges ahead. The volume thus focuses on i. Omics (genomics, proteomics, transcriptomics, metabolonomics) technologies in identifying, characterizing biodiversity ii. Role of molecular techniques for improvement of domestic and non-domestic organisms iii. Animal and alternative model systems (using stem cells, tissue engineering, cell free systems, 3D platforms etc.) for studying life phenomena iv. Genetically modified organisms as factories for the products

Climate Change Impact on Livestock: Adaptation and Mitigation

Author : Veerasamy Sejian
Publisher : Springer
ISBN 13 : 8132222652
Total Pages : 532 pages
Book Rating : 4.1/5 (322 download)

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Book Synopsis Climate Change Impact on Livestock: Adaptation and Mitigation by : Veerasamy Sejian

Download or read book Climate Change Impact on Livestock: Adaptation and Mitigation written by Veerasamy Sejian and published by Springer. This book was released on 2015-03-31 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume addresses in detail both livestock’s role in climate change and the impacts of climate change on livestock production and reproduction. Apart from these cardinal principles of climate change and livestock production, this volume also examines the various strategies used to mitigate livestock-related GHG emissions, and those which can reduce the impacts of climate change on livestock production and reproduction. Presenting information and case studies collected and analyzed by professionals working in diversified ecological zones, the book explores the influence of climate change on livestock production across the globe. The most significant feature of this book is that it addresses in detail the different adaptation strategies and identifies targets for different stakeholders in connection with climate change and livestock production. Further, it puts forward development plans that will allow the livestock industries to cope with current climate changes and strategies that will mitigate the effects by 2025. Lastly, it provides researchers and policymakers several researchable priorities to help develop economically viable solutions for livestock production with less GHG emissions, promoting a cleaner environment in which human beings and livestock can live in harmony without adverse effects on productivity. Given that livestock production systems are sensitive to climate change and at the same are themselves a contributor to the phenomenon, climate change has the potential to pose an increasingly formidable challenge to the development of the livestock sector. However, there is a dearth of scientific information on adapting livestock production to the changing climate; as such, well-founded reference material on sustaining livestock production systems under the changing climate scenarios in different agro-ecological zones of the world is essential. By methodically and extensively addressing all aspects of climate change and livestock production, this volume offers a valuable tool for understanding the hidden intricacies of climatic stress and its influence on livestock production.

The Rumen Microbial Ecosystem

Author : P.N. Hobson
Publisher : Springer Science & Business Media
ISBN 13 : 9400914539
Total Pages : 741 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis The Rumen Microbial Ecosystem by : P.N. Hobson

Download or read book The Rumen Microbial Ecosystem written by P.N. Hobson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 741 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Preface to the first edition of this book explained the reasons for the publication of a comprehensive text on the rumen and rumen microbes in 1988. The microbes of the ruminant's forestomach and those in related organs in other animals and birds provide the means by which herbivorous animals can digest and obtain nutriment from vegetation. In turn, humans have relied, and still do rely, on herbivores for much of their food, clothing and motive power. Herbivores also form the food of carnivorous animals and birds in the wild. The importance of the rumen microorganisms is thus apparent. But, while a knowledge of rumen organisms is not strictly neces sary for the normal, practical feeding of farm animals, in recent years there has been much more emphasis on increasing the productivity of domesti cated animals and in rearing farm animals on unusual feedstuffs. Here, a knowledge of the reactions of the rumen flora, and the limits to these reactions, can be invaluable. In addition, anaerobic rumen-type microor ganisms are found in the intestines of omnivores, including humans, and can be implicated in diseases of humans and animals. They are also found in soils and natural waters, where they playa part in causing pollution and also in reducing it, while the same organisms confined in artificial systems are essential for the purification of sewage and other polluting and toxic wastes.

Mining, Designing, Mechanisms and Applications of Extremophilic Enzymes

Author : Junpei Zhou
Publisher : Frontiers Media SA
ISBN 13 : 2889718751
Total Pages : 199 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Mining, Designing, Mechanisms and Applications of Extremophilic Enzymes by : Junpei Zhou

Download or read book Mining, Designing, Mechanisms and Applications of Extremophilic Enzymes written by Junpei Zhou and published by Frontiers Media SA. This book was released on 2021-12-29 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Rumen and Its Microbes

Author : Robert E. Hungate
Publisher : Elsevier
ISBN 13 : 1483263622
Total Pages : 544 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis The Rumen and Its Microbes by : Robert E. Hungate

Download or read book The Rumen and Its Microbes written by Robert E. Hungate and published by Elsevier. This book was released on 2013-10-22 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Rumen and Its Microbes is a contribution to the ecology of this important microbial habitat. Relatively few microbial habitats have been subjected to a thorough quantitative ecological analysis. The rumen fermentation is peculiarly suitable because of its relatively constant and continuous nature and because of the very rapid rates of conversion of organic matter. Although analysis of the ruminant-microbe symbiosis is still far from complete, knowledge is sufficient for formulation of principles and for identification and measurement of important parameters. The first eight chapters of the book include a description of the rumen and its microbes, their activities, and the extent of these activities. This basic biology provides a framework in which applications to agriculture can be evaluated. These applications are discussed in the last four chapters: host metabolism, variation in the rumen, possible practical applications, and abnormalities in rumen function.

Sustainable Microbial Technologies for Valorization of Agro-Industrial Wastes

Author : Jitendra Kumar Saini
Publisher : CRC Press
ISBN 13 : 1000655008
Total Pages : 377 pages
Book Rating : 4.0/5 (6 download)

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Book Synopsis Sustainable Microbial Technologies for Valorization of Agro-Industrial Wastes by : Jitendra Kumar Saini

Download or read book Sustainable Microbial Technologies for Valorization of Agro-Industrial Wastes written by Jitendra Kumar Saini and published by CRC Press. This book was released on 2022-09-30 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview of the different aspects of microbial bioconversion methodologies for valorization of underutilized wastes of varied nature. It covers microbiological/biotechnological aspects, environmental concerns, bioprocess development, scale-up aspects, challenges, and opportunities in microbial valorization at commercial scale. It explains sustainable microbiological processes for bioconversion and valorization of the wastes for production of various products of commercial interests, including biofuels, bioenergy, and other platform chemicals. The book • presents potential biotechnological topics and strategies for the valuation of agricultural waste materials; • provides technical concepts on the production of various commercially significant bioproducts; • introduces various microbial bioprocesses to sustainably valorize various potential wastes as renewable feedstocks for production of biofuels and biochemicals; • explores the relevant scale-up opportunities, commercialization aspects, and critical technological advances; and • explains concepts and recent trends in life cycle analyses in waste valorization. It is aimed at researchers and graduate students in bioengineering, biochemical engineering, microbial technology/microbiology, environmental engineering, and biotechnology.

Gut Microbiome Modulation in Ruminants: Enhancing Advantages and Minimizing Drawbacks

Author : Alejandro Belanche
Publisher : Frontiers Media SA
ISBN 13 : 288966483X
Total Pages : 437 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Gut Microbiome Modulation in Ruminants: Enhancing Advantages and Minimizing Drawbacks by : Alejandro Belanche

Download or read book Gut Microbiome Modulation in Ruminants: Enhancing Advantages and Minimizing Drawbacks written by Alejandro Belanche and published by Frontiers Media SA. This book was released on 2021-02-17 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The methane moment – Cross-boundary significance of methanogens

Author : Zhe Lyu
Publisher : Frontiers Media SA
ISBN 13 : 2832547389
Total Pages : 271 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis The methane moment – Cross-boundary significance of methanogens by : Zhe Lyu

Download or read book The methane moment – Cross-boundary significance of methanogens written by Zhe Lyu and published by Frontiers Media SA. This book was released on 2024-07-30 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methane is a potent greenhouse gas, a relatively clean burning fossil fuel, but also a renewable biofuel when biologically produced from waste treatment plants. Most (~70%) of the global methane emission comes from methanogenic archaea, namely methanogens that produce methane from simple substrates such as H2/CO2, formate, acetate, methanol, and other methylated compounds. Methanogens are found across all corners of the earth, including but not limited to wetlands, animals and humans, rice fields, landfills, sewage, ocean, termites, and hydrothermal vents. Their extensive adaptations to such a wide range of habitats predict a cross-boundary significance of methanogens in many areas such as the environment, energy, agriculture, biotechnology, and human and animal health. The goal of this Research Topic is to offer a forum that highlights the cross-boundary significance of methanogens by bringing together methanogen research from diverse settings to one place. This cross-boundary significance is currently underappreciated but imperative to collectively understanding and helping to solve some of the biggest and most urgent challenges humanity is facing such as global warming, food and energy insecurity, pollution, and disease. As a more potent and shorter-lived greenhouse gas than CO2, methane has moved to the center stage in our efforts in rapidly combating climate change. Presumably, methanogens and their associated microbes may have been forced into a positive feedback loop to fuel the sharp rise of methane in recent years. On the other hand, methanogens are considered keystone species in the ecosystem, which are vital to the stability of the natural biome therein. However, the roles of methanogens as keystone species across their habitats are underexplored. Moreover, the role of methanogens in human and animal intestinal microbiomes have been reconsidered with evidence for links to disease and impact on nutrition. Last but not the least, methanogens are emerging as a cell factory model for green manufacturing, because of their abilities to convert CO2 to valuable biochemicals. Further efforts in the bioengineering of methanogens have the potential to expand their commercial application from waste treatment to biomanufacturing. We welcome both basic and translational studies relevant to methanogens from any setting. Studies with a focus on methanogens are highly encouraged, and manuscripts having methanogens as a significant component are also welcome. All studies should emphasize and envisage their implications in understanding and/or solving one or more challenges humanity is facing. To encourage submissions from multiple disciplines, this Research Topic is cross-listed with a number of Frontiers journals and sections. Manuscripts in the forms of Original Research, Review (including systematic and mini review), Methods, Hypothesis and Theory, and Perspectives are all welcome. Manuscript summary submissions are highly encouraged but all manuscripts submitted prior to the manuscript submission deadline will receive full consideration. This Research Topic is dedicated to Dr. William Barny Whitman, Emeritus Professor of Microbiology at the University of Georgia, Athens, GA. His 40+ years (and still counting) of productive research in methanogens, roseobacter, and other prokaryotes have contributed to and will continue to inspire new discoveries in the cross-boundary significance of both archaea and bacteria – the unseen majority. COI Statement: S.K.-M.R.R. is co-founder of Arkeon GmbH. M.P. is a consultant for Bausch Health, Ferring Pharmaceuticals Inc., Salvo Health, and Vivante Health Inc.