Metals In Carbohydrate Synthesis

Download Metals In Carbohydrate Synthesis full books in PDF, epub, and Kindle. Read online Metals In Carbohydrate Synthesis ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

Metals in Carbohydrate Synthesis

Author : Christopher Albler
Publisher : Sudwestdeutscher Verlag Fur Hochschulschriften AG
ISBN 13 : 9783838150895
Total Pages : 196 pages
Book Rating : 4.1/5 (58 download)

DOWNLOAD NOW!

Book Synopsis Metals in Carbohydrate Synthesis by : Christopher Albler

Download or read book Metals in Carbohydrate Synthesis written by Christopher Albler and published by Sudwestdeutscher Verlag Fur Hochschulschriften AG. This book was released on 2015-04-14 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes two different projects associated with the chemical (de novo) synthesis of rare and unnatural carbohydrates from readily available starting materials. After a comprehensive introduction to indium chemistry and stereoselective aldol reactions, two new methodologies are presented which complement the synthetic arsenal available to the carbohydrate chemist. The indium mediated allylation of unprotected carbohydrates was applied in the synthesis of acetamido-heptoses and octoses which are constituents of the aminoglycoside antibiotics Apramycin and Destomycin. Furthermore, a new approach for the incorporation of fluorine into carbohydrates is described. Amino acid building blocks were chain-elongated via a titanium mediated aldol addition, finally furnishing amino-, fluoro-functionalised pentoses and hexoses. These compounds are of high interest not only concerning their potential antimicrobial activity but also their usefulness in elucidating fundamental biological processes such as antigen-antibody aggregation.

Application of Transition Metal Reagents and Catalysts in Carbohydrate Synthesis

Author : Zaher S. Hanna
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (541 download)

DOWNLOAD NOW!

Book Synopsis Application of Transition Metal Reagents and Catalysts in Carbohydrate Synthesis by : Zaher S. Hanna

Download or read book Application of Transition Metal Reagents and Catalysts in Carbohydrate Synthesis written by Zaher S. Hanna and published by . This book was released on 1981 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Functionalization of Carbohydrates Toward Metal Binding

Author : Nabyl Merbouh
Publisher :
ISBN 13 :
Total Pages : 376 pages
Book Rating : 4.:/5 (555 download)

DOWNLOAD NOW!

Book Synopsis Functionalization of Carbohydrates Toward Metal Binding by : Nabyl Merbouh

Download or read book Functionalization of Carbohydrates Toward Metal Binding written by Nabyl Merbouh and published by . This book was released on 2004 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Polysaccharides

Author : Kishan Gopal Ramawat
Publisher : Springer
ISBN 13 : 9783319162973
Total Pages : 0 pages
Book Rating : 4.1/5 (629 download)

DOWNLOAD NOW!

Book Synopsis Polysaccharides by : Kishan Gopal Ramawat

Download or read book Polysaccharides written by Kishan Gopal Ramawat and published by Springer. This book was released on 2015-07-21 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This authoritative reference work presents comprehensive information about one of the most important and most wide-spread classes of (bio)organic compounds: the polysaccharides. The comprehensive and thoroughly up-to-date handbook presents the sources, identification, analysis, biosynthesis, biotechnology and applications of important polysaccharides likes starches, cellulose, chitin, gum and microbial polysaccharides. Polysaccharides can exhibit complex structure and various functional activities. These bio macromolecules can therefore serve as raw materials for various different materials, e.g. rayon, cellulose acetate, celluloid and nitrocellulose; and they find multiple applications, for instance as surgical threads (chitin), as sources of energy, dietary fibers, as blood flow adjuvants, in cosmetics, emulsion stabilizers, film formers, binders, viscosity increasing agents or skin conditioning agenta, as food additives in gums, chewing gum bases and as vaccines. Polysaccharides form the basis for useful products, like xanthan gum, dextran, welan gum, gellan gum, diutan gum and pullulan. Some of the polysaccharide-derived products have interesting and useful properties and show biological activities, such as immunomodulatory, antibacterial, anti-mutagenic, radioprotective, anti-oxidative, anti-ulcer, antidepressant, anti-septicaemic or anti-inflammatory activities. All these applications and properties of polysaccharides are for the first time compiled in a thorough and comprehensive overview in the present work. This reference work is organized thematically in four parts: Part I. Polysaccharides: Occurrence, Structure, Distribution and Biotechnology. Part II. Methods. Part III. Bioactive Polysaccharides. Part IV. Polysaccharides as Food. This reference work is edited by experienced experts, all chapters are written by well recognized international specialists. It is useful to all those working in the field of botany, phytochemistry, pharmacy, drug delivery, molecular biology, metabolomics, forestry, environment, conservation, biotechnology and NGOs working for forest protection.

Towards the Synthesis of Transition Metal Derivatives of Carbohydrates

Author : Arlene Marie Slee
Publisher :
ISBN 13 :
Total Pages : 268 pages
Book Rating : 4.:/5 (66 download)

DOWNLOAD NOW!

Book Synopsis Towards the Synthesis of Transition Metal Derivatives of Carbohydrates by : Arlene Marie Slee

Download or read book Towards the Synthesis of Transition Metal Derivatives of Carbohydrates written by Arlene Marie Slee and published by . This book was released on 1973 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Reacting Carbohydrates with Metals and Metal Complexes

Author : Philip Robert Skaanderup
Publisher :
ISBN 13 :
Total Pages : 94 pages
Book Rating : 4.:/5 (471 download)

DOWNLOAD NOW!

Book Synopsis Reacting Carbohydrates with Metals and Metal Complexes by : Philip Robert Skaanderup

Download or read book Reacting Carbohydrates with Metals and Metal Complexes written by Philip Robert Skaanderup and published by . This book was released on 2002 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Application of Carbohydrate Derivatives in Asymmetric Synthesis and as Ligands in Metal Ion Complexes

Author : Sine Abraham Johannesen
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (12 download)

DOWNLOAD NOW!

Book Synopsis Application of Carbohydrate Derivatives in Asymmetric Synthesis and as Ligands in Metal Ion Complexes by : Sine Abraham Johannesen

Download or read book Application of Carbohydrate Derivatives in Asymmetric Synthesis and as Ligands in Metal Ion Complexes written by Sine Abraham Johannesen and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Application of Carbohydrate Derivatives in Asymmetric Synthesis and as Ligands in Metal Ion Complexes

Author : Sine Abraham Johannesen
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (872 download)

DOWNLOAD NOW!

Book Synopsis Application of Carbohydrate Derivatives in Asymmetric Synthesis and as Ligands in Metal Ion Complexes by : Sine Abraham Johannesen

Studies and applications of metals for the synthesis of carbinols, amides and carbohydrates

Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (778 download)

DOWNLOAD NOW!

Book Synopsis Studies and applications of metals for the synthesis of carbinols, amides and carbohydrates by :

Download or read book Studies and applications of metals for the synthesis of carbinols, amides and carbohydrates written by and published by . This book was released on 2011 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Carbohydrates

Author : Mike Martin Kwabena Boysen
Publisher : John Wiley & Sons
ISBN 13 : 3527654569
Total Pages : 386 pages
Book Rating : 4.5/5 (276 download)

DOWNLOAD NOW!

Book Synopsis Carbohydrates by : Mike Martin Kwabena Boysen

Download or read book Carbohydrates written by Mike Martin Kwabena Boysen and published by John Wiley & Sons. This book was released on 2012-11-26 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Closing a gap in the literature, this comprehensive book presents the utility of carbohydrate derivatives as chiral auxiliaries, reagents, complex ligands and organocatalysts, together with details of their preparation, as well as their successful application in stereoselective synthesis. Divided into four parts: * Carbohydrate Auxiliaries * Carbohydrate Reagents * Carbohydrate Ligands * Carbohydrate Organocatalysts It is an indispensable source for every organic chemist.

Metal-Organic Frameworks for Biomedical Applications

Author : Masoud Mozafari
Publisher : Woodhead Publishing
ISBN 13 : 0128169842
Total Pages : 584 pages
Book Rating : 4.1/5 (281 download)

DOWNLOAD NOW!

Book Synopsis Metal-Organic Frameworks for Biomedical Applications by : Masoud Mozafari

Download or read book Metal-Organic Frameworks for Biomedical Applications written by Masoud Mozafari and published by Woodhead Publishing. This book was released on 2020-03-17 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal-Organic Frameworks for Biomedical Applications is a comprehensive, authoritative reference that offers a substantial and complete treatment of published results that have yet to be critically reviewed. It offers a summary of current research and provides in-depth understanding of the role of metal-organic frameworks in biomedical engineering. The title consists of twenty-two chapters presented by leading international researchers in the field. Chapters are arranged by target-application in biomedical engineering, allowing medical and pharmaceutic specialists to translate current materials and engineering science on metal-organic frameworks into their work. Presents the state-of-the art in metal-organic frameworks for biomedical applications Offers comprehensive treatment of metal-organic frameworks that is useful to pharmaceutic and medical experts who are non-specialists in materials science Helps materials scientists and engineers understand the needs of biomedical engineering Critically-reviews published results and current research in the field

Synthesis of Nanoporous Carbohydrate Metal-organic Framework and Encapsulation of Selected Organic Compounds

Author : Saleh Al-Ghamdi
Publisher :
ISBN 13 : 9781321443684
Total Pages : 102 pages
Book Rating : 4.4/5 (436 download)

DOWNLOAD NOW!

Book Synopsis Synthesis of Nanoporous Carbohydrate Metal-organic Framework and Encapsulation of Selected Organic Compounds by : Saleh Al-Ghamdi

Download or read book Synthesis of Nanoporous Carbohydrate Metal-organic Framework and Encapsulation of Selected Organic Compounds written by Saleh Al-Ghamdi and published by . This book was released on 2014 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Organic Corrosion Inhibitors

Author : Chandrabhan Verma
Publisher : John Wiley & Sons
ISBN 13 : 1119794501
Total Pages : 530 pages
Book Rating : 4.1/5 (197 download)

DOWNLOAD NOW!

Book Synopsis Organic Corrosion Inhibitors by : Chandrabhan Verma

Download or read book Organic Corrosion Inhibitors written by Chandrabhan Verma and published by John Wiley & Sons. This book was released on 2021-09-11 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides comprehensive coverage of organic corrosion inhibitors used in modern industrial platforms, including current developments in the design of promising classes of organic corrosion inhibitors Corrosion is the cause of significant economic and safety-related problems that span across industries and applications, including production and processing operations, transportation and public utilities infrastructure, and oil and gas exploration. The use of organic corrosion inhibitors is a simple and cost-effective method for protecting processes, machinery, and materials while remaining environmentally acceptable. Organic Corrosion Inhibitors: Synthesis, Characterization, Mechanism, and Applications provides up-to-date coverage of all aspects of organic corrosion inhibitors, including their fundamental characteristics, synthesis, characterization, inhibition mechanism, and industrial applications. Divided into five sections, the text first covers the basics of corrosion and prevention, experimental and computational testing, and the differences between organic and inorganic corrosion inhibitors. The next section describes various heterocyclic and non-heterocyclic corrosion inhibitors, followed by discussion of the corrosion inhibition characteristics of carbohydrates, amino acids, and other organic green corrosion inhibitors. The final two sections examine the corrosion inhibition properties of carbon nanotubes and graphene oxide, and review the application of natural and synthetic polymers as corrosion inhibitors. Featuring contributions by leading researchers and scientists from academia and industry, this authoritative volume: Discusses the latest developments and issues in the area of corrosion inhibition, including manufacturing challenges and new industrial applications Explores the development and implementation of environmentally-friendly alternatives to traditional toxic corrosion inhibitors Covers both established and emerging classes of corrosion inhibitors as well as future research directions Describes the anticorrosive mechanisms and effects of acyclic, cyclic, natural, and synthetic corrosion inhibitors Offering an interdisciplinary approach to the subject, Organic Corrosion Inhibitors: Synthesis, Characterization, Mechanism, and Applications is essential reading for chemists, chemical engineers, researchers, industry professionals, and advanced students working in fields such as corrosion inhibitors, corrosion engineering, materials science, and applied chemistry.

Advances in Carbohydrate Chemistry

Author :
Publisher : Academic Press
ISBN 13 : 0080562809
Total Pages : 585 pages
Book Rating : 4.0/5 (85 download)

DOWNLOAD NOW!

Book Synopsis Advances in Carbohydrate Chemistry by :

Download or read book Advances in Carbohydrate Chemistry written by and published by Academic Press. This book was released on 1967-01-01 with total page 585 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Carbohydrate Chemistry

Development of Novel Glycosylation Reactions Using Transition Metals Or Organocatalysts

Author : Haoyuan Wang
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (11 download)

DOWNLOAD NOW!

Book Synopsis Development of Novel Glycosylation Reactions Using Transition Metals Or Organocatalysts by : Haoyuan Wang

Download or read book Development of Novel Glycosylation Reactions Using Transition Metals Or Organocatalysts written by Haoyuan Wang and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carbohydrates play a significant role in many biological events, such as cell-cell communications, intercellular recognitions, and blood group identifications. Monosaccharides, oligosaccharides, polysaccharides and their glycoconjugates such as glycoproteins and glycolipids are also involved in various diseases including tumor formation, metastasis, bacterial and viral infections. Numerous carbohydrate-based drugs and vaccines have been approved or are in different phases of clinical trials. Although many methods have been developed for the synthesis of carbohydrates, stereoselective glycosidic bond formation is still challenging. One of the biggest bottleneck for glycobiology researchers is still the lack of a general way to obtain homogeneous forms of glycans in a reliable and scalable fashion. Over the past 3 years, I have developed several novel glycosylation reactions that could be used to synthesize carbohydrates and glycoconjugates stereoselectively. In my first project, I developed two reactions that use transition metal catalysts such as iridium or palladium in combination with Brønsted acid promoter, to realize a dynamic kinetic diastereoselective glycosylation (DKDG) and a dynamic kinetic diastereoselective isomerization (DKDI). I also demonstrated the products of DKDG and DKDI could be applied to the synthesis of rare and unnatural mono- and oligo-saccharides. Inspired by the mechanistic understandings on the first project, I developed an organocatalyst-directed dynamic kinetic diastereoselective acylation of lactols (DKDA) in my second project. This DKDA reaction provides a convenient solution to a long standing problem in Feringa-O'Doberty's de novo carbohydrate synthesis. The transition-state model of DKDA indicated a novel type of cation-lone pair electrostatic interaction. Based on this model, I developed a second generation of DKDA (DKDA-2.0) by using monosaccharide substrates to realize stereoselective synthesis of different 1-acyl sugars which exist in many natural products, drug metabolites and have been applied to drug delivery. In the last project, I developed a novel stable glycosyl donor with a traceless isoquinoline-1-carboxylate (IsQ) leaving group that could be activated by copper salt for glycosylation reaction under neutral and extremely mild conditions (Glyco-IsQ). I also demonstrated the broad scope of the glycosylation donor in over a dozen of examples and its orthogonality with another ester glycosyl donor in a streamlined iterative synthesis of oligosaccharides, without involving any protection, deprotection, or activation steps during the assembly of the oligosaccharides. A tetra-saccharide was assembled in just 3 steps by using this iterative synthesis strategy.

Protecting Groups: Strategies and Applications in Carbohydrate Chemistry

Author : Sebastien Vidal
Publisher : John Wiley & Sons
ISBN 13 : 3527340106
Total Pages : 522 pages
Book Rating : 4.5/5 (273 download)

DOWNLOAD NOW!

Book Synopsis Protecting Groups: Strategies and Applications in Carbohydrate Chemistry by : Sebastien Vidal

Download or read book Protecting Groups: Strategies and Applications in Carbohydrate Chemistry written by Sebastien Vidal and published by John Wiley & Sons. This book was released on 2019-04-29 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: A unique overview of the most important protecting group strategies in carbohydrate chemistry Protecting Groups: Strategies and Applications in Carbohydrate Chemistry provides a detailed account of key strategies and methodologies for the protection of carbohydrates. Divided into two parts, the first focuses on groups that are used best to protect a specific position on a carbohydrate. In the second part, specific carbohydrate residues or compounds are discussed in the context of a specific protecting group strategy used to reach the desired regioisomer. This important book: -Features chapters on protecting groups at the primary and secondary positions of carbohydrates -Describes protecting group strategies towards sialic acid derivatives, glycofuranoses, sulfated glycosaminoglycans, and cyclodextrins -Provides information on automated glycan assembly -Includes a chapter on the industrial scale synthesis of heparin analogs Written by a team of leaders in the field, Protecting Groups: Strategies and Applications in Carbohydrate Chemistry is an indispensable guide for academics and industrial researchers interested in carbohydrate and natural product synthesis, pharmaceutical chemistry, and biochemistry.

Development of Transition Metal-catalyzed Site-selective Carbohydrate Functionalization Reactions and Tissue-selective Protein Degraders

Download Development of Transition Metal-catalyzed Site-selective Carbohydrate Functionalization Reactions and Tissue-selective Protein Degraders PDF Online Free

Author : Xiaolei Li (Ph.D.)
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (139 download)

DOWNLOAD NOW!

Book Synopsis Development of Transition Metal-catalyzed Site-selective Carbohydrate Functionalization Reactions and Tissue-selective Protein Degraders by : Xiaolei Li (Ph.D.)

Download or read book Development of Transition Metal-catalyzed Site-selective Carbohydrate Functionalization Reactions and Tissue-selective Protein Degraders written by Xiaolei Li (Ph.D.) and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carbohydrates are synthetically challenging molecules with vital biological roles in all living systems. To better understand the biological functions of this fundamentally important class of molecules, novel methodologies are urgently needed in two different directions: building block synthesis and selective glycosylation. During my Ph.D. study, I developed two different methodologies for building block synthesis, which could simplify the assembly of oligosaccharides.Differentiation of hydroxy groups on the carbohydrate is usually considered challenging as a result of the almost identical chemical environment. 1,2-trans diols are even more difficult to deal with compared to 1,2-cis diols. In my first project, I developed a method for regio- and stereo-selective OH carbene insertion together with my collaborator. Under very mild conditions, a series of 1,2-trans diols can be selectively functionalized. The regioselectivity originated from interactions between substrates and transition-metal catalysts, while the stereochemistry came from intramolecular proton delivery. The newly introduced moiety can work as a protection group, function group for the glycoconjugate mimic synthesis, or participate in the following glycosylation reactions and impact the anomeric selectivity. Inspired by the regio-selectivity of first projects, I developed another transition metal-catalyzed reaction, which could successfully epimerize one hydroxyl group in 1,2-trans diols, thus many rare sugars can be accessed easily starting from readily available common sugars. Compared to the traditional route, the method I developed can simplify the synthesis significantly and is more environmentally friendly. Synthesis of aminosugars through direct amination of 1,2-trans diols is also investigated. Bromodomain (BRD) is an evolutionarily conserved protein-protein interaction module that can recognize and bind acetylated lysine residues in histones and many other proteins. BRD4 protein, which is considered a transcriptional factor and epigenetic regulator, can bind to acetylated histone and recruit protein complexes to stabilize the binding of RNA polymerase II to histone. The dysregulation of BRD4 can cause cancer and other diseases such as immune and inflammatory diseases. Because of this, the BRD4 protein has been long considered an important therapeutic target. In the third project, I worked on the development of tissue-selective BRD4 degraders, aiming to provide a novel therapy for prostate cancer. By attaching tissue-selective ligands to BRD4 degraders, we successfully achieved selectivity among different cell lines, which proved our initial hypothesis. The tri-functional degraders will be tested in vivo in the future.