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Metal Neurotoxicity
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Book Synopsis Poisoning in the Modern World by : Ozgur Karcioglu
Download or read book Poisoning in the Modern World written by Ozgur Karcioglu and published by BoD – Books on Demand. This book was released on 2019-06-19 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over 400 years ago, Swiss alchemist and physician Paracelsus (1493-1541) cited: "All substances are poisons; there is none that is not a poison. The right dose differentiates a poison from a remedy." This is often condensed to: "The dose makes the poison." So, why are we overtly anxious about intoxications?In fact, poisons became a global problem with the industrial revolution. Pesticides, asbestos, occupational chemicals, air pollution, and heavy metal toxicity maintain high priority worldwide, especially in developing countries. Children between 0 and 5 years old are the most vulnerable to both acute and chronic poisonings, while older adults suffer from the chronic effects of chemicals. This book aims to raise awareness about the challenges of poisons, to help clinicians understand current issues in toxicology.
Book Synopsis Neurotoxicity of Metals: Old Issues and New Developments by :
Download or read book Neurotoxicity of Metals: Old Issues and New Developments written by and published by Academic Press. This book was released on 2021-04-17 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: The volume discusses novel issues associated with the neurotoxicity of select metals Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Advances in Neurotoxicology series Updated release includes the latest information on the mechanisms associated with neurodegeneration, neurodevelopmental effects, and brain accumulation of metals New approaches for the study of metal neurotoxicity
Download or read book Occupational Neurology written by and published by Elsevier. This book was released on 2015-11-09 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt: Occupational Neurology a volume in the Handbook of Clinical Neurology Series, provides a comprehensive overview of the science, clinical diagnosis, and treatment for neurotoxin related neurological and psychiatric disorders. This timely collection provides not only a complete scientific reference on the chemical origin of this class of neurological and psychiatric disorders, but also a practical guide to diagnosis and treatment challenges and best practices. Handbook of Clinical Neurology Series The first volume of the Handbook of Clinical Neurology under the editorship of George Bruyn and Pierre Vinken was published in 1968. In 1982, the series was brought to an interim conclusion with the publication of the cumulative index volume (Volume 44). By that stage, the Handbook had come to represent one of the largest scientific works ever published. It enjoys a high reputation in specialist media circles throughout the world. After the series was concluded in 1982, it was realized that an update of the material was imperative. Accordingly, a revised series was planned and published over the following years, concluding with the publication of another cumulative index to both series (Volume 76-78) in 2002. Since then, George Bruyn has passed away and Pierre Vinken has retired, but the need for a further new series, incorporating advances in the field, again become necessary. Professors Michael J. Aminoff, François Boller and Dick F. Swaab have with enthusiasm taken on the responsibility of supervising the preparation of a third series, the first volumes of which were published in 2003. Now, more than 130 volumes after the first published, the Handbook of Clinical Neurology series continues to have an unparalleled reputation for providing the latest foundational research, diagnosis, and treatment protocols essential for both basic neuroscience research and clinical neurology. Provides comprehensive coverage of neurotoxins, especially in the workplace Details the latest science as the foundation for neurotoxicity diagnosis and treatment Presents coverage of the diagnosis and treatment essential for clinical neurologists and occupational medicine specialists
Book Synopsis Neurotoxicity of Metals by : Michael Aschner
Download or read book Neurotoxicity of Metals written by Michael Aschner and published by Springer. This book was released on 2017-09-09 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: Assembles international authorities to address contemporary research in metal neurotoxicity. Essential and non-essential metals play an important role in neurodevelopmental and neurodegenerative diseases. Recent developments in understanding the role of metals in the etiology of these disorders have led to rapid growth in clarifying the pathology of some of the most devastating diseases we face and in identifying potential new therapies. Few books or periodicals have been wholly dedicated to the topic of metals, and this collection is intended to serve as a resource for all researchers interested in metals and their role in health and disease.
Book Synopsis METAL NEUROTOXICITY by : Kedar N. Prasad
Download or read book METAL NEUROTOXICITY written by Kedar N. Prasad and published by Chapman & Hall/CRC. This book was released on 1988 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Metal Toxicity and Tolerance in Plants and Animals by : V. P. Singh
Download or read book Metal Toxicity and Tolerance in Plants and Animals written by V. P. Singh and published by Sarup & Sons. This book was released on 2005 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Heavy Metal Toxicity in Public Health by : John Kanayochukwu Nduka
Download or read book Heavy Metal Toxicity in Public Health written by John Kanayochukwu Nduka and published by BoD – Books on Demand. This book was released on 2020-06-24 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is often said that the “dosage” of any substance determines its remedy or poison effect. Heavy metal sources encompass sewage, pesticides, fertilizers, environmental contamination, occupational exposure/contact through inhalation, ingestion, and skin. Before the advent of technology/the industrial revolution, communicable diseases ravaged the human race but this seems to have given way to non-communicable diseases such as cancers, renal failure, hormonal distortion enzymes, inhibition of fetal growth, and DNA damage causing negative health issues due to heavy metals. This book brings to the fore probably the most recent experimental research/review on heavy metal contamination, remediating techniques, cellular tissue damage, and toxicological and antioxidant effects of heavy metals. It is hoped that its contents will make interesting reading for all.
Book Synopsis Genetic Heavy Metal Toxicity by : Tara Lang Chapman
Download or read book Genetic Heavy Metal Toxicity written by Tara Lang Chapman and published by iUniverse. This book was released on 2008 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: Book claims that heavy metal poisoning is the cause of many neurological disorders, and is passed on from one generation to the next through epigenetics.
Book Synopsis Metal Toxicology Handbook by : Debasis Bagchi
Download or read book Metal Toxicology Handbook written by Debasis Bagchi and published by CRC Press. This book was released on 2020-11-19 with total page 511 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heavy metals and metalloids, singly or in combination, induce toxic manifestations either through acute or chronic pathology. In particular, long-term chronic exposure to diverse heavy metals and metalloids to humans and animals can lead to numerous physical, muscular, neurological, nephrological, and diverse degenerative diseases and dysfunctions, including multiple sclerosis, muscular dystrophy, Parkinson’s and Alzheimer’s diseases, cardiovascular disorders, and several others. Recognized heavy metals such as lead, mercury, arsenic, cadmium, thallium, and hexavalent chromium are known for enormous toxicity. The immediate vital signs of acute heavy metal exposure include nausea, vomiting, diarrhea, and acute abdominal pain. Mercury has been identified as the most toxic heavy metal, and mercury poisoning is known as acrodynia or pink disease. Similarly, lead, another toxic heavy metal, was at one time an integral part of painting. Metal Toxicology Handbook further explains and discusses the varying attributes of metals, discussing toxicity, safety, and proper human utilization of metals. Beginning with a broad overview of metals, metalloids, redox biology, and neurodegeneration and going further into the roles, benefits, and toxicity of metals with each section, the text contains 28 chapters from eminent researchers and scientists in their respective fields and is a must-have for anyone researching the potential toxicity in metals. Key Features Discusses the pathology of metal toxicity Highlights the benefits of metals Explains the mechanism and salient features of restoring metabolic homeostasis Highlights dose-dependent beneficial and adverse effects of vanadium safety and toxicity The initial introductory section provides a broad overview of metals, metalloids, redox biology, and neurodegeneration. The second section discusses the pathology of metal toxicity in two chapters, while the third section highlights the mechanism and salient features of restoring metabolic homeostasis in two chapters. The fourth section demonstrates the aspect of radionuclides toxicity. In a change of pace, the fifth section discusses the benefits of metals in four chapters. The sixth section, titled "Toxic Manifestations by Diverse Heavy Metals and Metalloids," provides fourteen chapters that discuss the toxicological mechanism and manifestation of individual metals. The editors have crafted a commentary titled "A Treatise on Metal Toxicity" and summarized a vivid scenario of metal toxicity and its consequences.
Download or read book Heavy Metals written by Kenneth R. Spaeth and published by Nova Science Pub Incorporated. This book was released on 2010-01-01 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exposure to toxic metals remains a public health hazard around the globe. Though the prevalence and intensity of exposure may vary from place to place, metal toxicity has been, and will continue to be, a challenge to recognise, treat and control. This book is made for the busy clinician and is focused on neurotoxicity. The authors review five metals that are neurotoxic (arsenic, lead, manganese, mercury, and thallium), and discuss the clinical approach to patients potentially exposed to these toxicants. It is simply written, current and evidence-based. This book makes an excellent companion to the clinician's shelf.
Book Synopsis Metal Toxicology by : Robert A. Goyer
Download or read book Metal Toxicology written by Robert A. Goyer and published by Elsevier. This book was released on 2013-10-22 with total page 550 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal Toxicology addresses the effects of metals on human health, as well as their mechanisms of toxicity. Unlike most books on metal toxicity which are organized by individual metals, this book is arranged inan organ-by-organ basis. It deals with unifying mechanisms of metal toxicity within a given tissue, and with exposure of a tissue to more than one metal at a time. Unique aspect of organ-specific orientationWritten by leading authorities in metal toxicologyChapters of special interest include Risk Assessment, Emerging Technologies, and Molecular Biological TechniquesServes as an excellent sourcebook of generalized information on metal toxicology, allowing for specific tissue-system referencing
Book Synopsis Metal Neurotoxicity by : Ed Bondy SC
Download or read book Metal Neurotoxicity written by Ed Bondy SC and published by . This book was released on 1988 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The neurotoxicity of organic and inorganic lead; Neurotoxic effects of manganese; Thallium toxicity and the nervous system; The neurotoxicity of copper; Aluminum; Neurotoxicity of the alkyltins; Neurological toxicity of lithium; Tissue culture model to study the effect of heavy metals; Cadmium neurotoxicity; Neurotoxicity of methyl mercury, cellular and subcellular aspects.
Book Synopsis Neurotoxicity of Aluminum by : Qiao Niu
Download or read book Neurotoxicity of Aluminum written by Qiao Niu and published by Springer. This book was released on 2018-10-12 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the scientific literature and the authors’ own research linking aluminum neurotoxicity with cognitive impairment and Alzheimer’s disease (AD). It focuses on aluminum levels in the brain, region-specific and subcellular distribution, and its relation to neurofibrillary tangles and amyloid beta. Further, the book stresses the importance of aluminum’s complex speciation chemistry in relation to biology, and details aluminum’s mechanism in oxidative stress and cell death, especially in connection with apoptosis and necroptosis. The electrophysiological variation and synaptic plasticity induced by aluminum are covered, while the metal’s debatable role in AD and the cross-talk between aluminum and genetic susceptibility are also discussed. In closing, the book reviews the neurotoxic effects of aluminum and its important role in the pathogenesis of AD. Given its depth of coverage, the book provides readers with a systematic summary of aluminum neurotoxicity.
Book Synopsis Cellular Effects of Heavy Metals by : Gaspar Banfalvi
Download or read book Cellular Effects of Heavy Metals written by Gaspar Banfalvi and published by Springer Science & Business Media. This book was released on 2011-03-02 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: The term “heavy metals” is used as a group name of toxic metals and metalloids (semimetals) causing contaminations and ecotoxicity. In strict chemical sense the density of heavy metals is higher than 5 g/cm3. From biological point of view as microelements they can be divided into two major groups. a. For their physiological function organisms and cells require essential microelements such as iron, chromium (III), cobalt, copper, manganese, molidenium, zinc. b. The other group of heavy metals is toxic to the health or environment. Of highest concern are the emissions of As, Cd, Co, Cu, Hg, Mn, Ni, Pb, Sn, Tl. The toxicity of heavy metals is well known at organizational level, while less attention has been paid to their cellular effects. This book describes the toxicity of heavy metals on microorganisms, yeast, plant and animal cells. Other chapters of the book deal with their genotoxic, mutagenic and carcinogenic effects. The toxicity of several metals touch upon the aspects of environmental hazard, ecosystems and human health. Among the cellular responses of heavy metals irregularities in cellular mechanisms such as gene expression, protein folding, stress signaling pathways are among the most important ones. The final chapters deal with biosensors and removal of heavy metals. As everybody is eating, drinking and exposed to heavy metals on a daily basis, the spirit of the book will attract a wide audience.
Book Synopsis Metal Chelation in Medicine by : Robert R Crichton
Download or read book Metal Chelation in Medicine written by Robert R Crichton and published by Royal Society of Chemistry. This book was released on 2016-10-18 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal chelators are emerging as versatile tool with many medical applications. Their versatility allows them to be used in chelation therapy for treating diseases caused by toxic and heavy metal poisoning, chelating agents are capable of binding to toxic metal ions to form complex structures which are easily excreted from the body removing them from intracellular or extracellular spaces. In addition, metal chelators can also be applied as contrast agents in MRI scanning. Metal Chelation in Medicine provides a clear and timely perspective on the role of chelating agents in the management of metal intoxications and storage diseases. Written by leaders in the field of chelators, this publication is at the cutting-edge of the subject. It covers a broad range of topics such as the use of metal chelators in non-invasive assessment of brain iron overload, and the treatment of systemic iron overload and neurodegenerative diseases. As such it is particularly valuable to clinicians treating metal poisonings and metal storage diseases. However, it is also a useful text for researchers, industry professionals and university students with a specific interest in medicinal chemistry, chelation, metal ions, imaging and non-invasive techniques.
Book Synopsis Metal, Metal Oxides and Metal Sulphides for Biomedical Applications by : Saravanan Rajendran
Download or read book Metal, Metal Oxides and Metal Sulphides for Biomedical Applications written by Saravanan Rajendran and published by Springer Nature. This book was released on 2021-01-25 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents recent advances in inorganic nanomaterials for healthcare, with focus on the synthesis, medical applications and toxicity of metals, metal oxides and metal sulfides. Major applications include diagnosis, bioimaging, biosensing, healing and therapy in cancer, diabetes, cardiovascular diseases, obesity, metabolic syndrome, dentistry and antimicrobials.
Book Synopsis Physiologic and Chemical Basis for Metal Toxicity by : B. Venugopal
Download or read book Physiologic and Chemical Basis for Metal Toxicity written by B. Venugopal and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our purpose is to provide understanding for appropriate use of metals in a technical society. Knowledge of metal toxicity is needed for the preven tion, prediction, diagnosis, and therapy of adverse reactions from excess metals in mammals. Metal Toxicity in Mammals is presented in two volumes. Volume 1, Physiologic and Chemical Basis for Metal Toxic ity, provides the basis for understanding the toxic actions of metals recorded in Volume 2, Chemical Toxicity of Metals and Metalloids. The details and bases for many concepts summarized in Volume I are given, with appropriate references, in Volume 2. Thus, references for specific items in Volume 2 are not generally given in Volume 1. The authors reviewed the known toxicity of several heavy metals in anticipation of their use as multinutrient markers for NASA. As more and more metals were considered, the need for a complete review became obvious. This treatise supplants onerous searches of metal-toxicity litera ture up to 1975 and reviews the toxicity of all the metals of the periodic table on the basis of available relevant data. Books on pharmacological, nutritional, medical, veterinary, or industrial toxicity contain information about selected metals. More complete data about metals of public concern, such as mercury, lead, and cadmium, may be found in numerous books and reviews. The reader should refer to general texts and basic reference works, when specific references are not given, for general information.
