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Metabolism Of Pesticides An Update
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Book Synopsis Pesticide Biotransformation and Disposition by : Ernest Hodgson
Download or read book Pesticide Biotransformation and Disposition written by Ernest Hodgson and published by Academic Press. This book was released on 2012-01-01 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biotransformation of Pesticides is an updated, "one-stop" resource for academic, industry and regulatory scientists involved in research and regulatory activities related to pesticide biotransformation and human health. This book provides an in depth look at how pesticides are biotransformed, which is essential to understanding exposure, dose, toxicity and health risks. This essential reference contains the biotransformation of pesticides from uptake to excretion, including toxicokinetics and emphasizes metabolism in non-target species, including experimental animals and humans. - Includes four new chapters and expanded material on pesticide biotransformation and disposition, an active area of pesticide toxicology that is becoming increasingly important for human health risk assessment - Offers a practical and portable guide covering the most up-to-date research results on metabolic transformations of pesticides - Provides scientists and regulatory researchers with the information they need to conduct accurate risk assessments and make informed decisions on which exposures to study further in human populations
Book Synopsis Intentional Human Dosing Studies for EPA Regulatory Purposes by : National Research Council
Download or read book Intentional Human Dosing Studies for EPA Regulatory Purposes written by National Research Council and published by National Academies Press. This book was released on 2004-06-04 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: The EPA commissioned The National Academies to provide advice on the vexing question of whether and, if so, under what circumstances EPA should accept and consider intentional human dosing studies conducted by companies or other sources outside the agency (so-called third parties) to gather evidence relating to the risks of a chemical or the conditions under which exposure to it could be judged safe. This report recommends that such studies be conducted and used for regulatory purposes only if all of several strict conditions are met, including the following: The study is necessary and scientifically valid, meaning that it addresses an important regulatory question that can't be answered with animal studies or nondosing human studies; The societal benefits of the study outweigh any anticipated risks to participants. At no time, even when benefits beyond improved regulation exist, can a human dosing study be justified that is anticipated to cause lasting harm to study participants; and All recognized ethical standards and procedures for protecting the interests of study participants are observed. In addition, EPA should establish a Human Studies Review Board (HSRB) to evaluate all human dosing studiesâ€"both at the beginning and upon completion of the experimentsâ€"if they are carried out with the intent of affecting the agency's policy-making.
Book Synopsis Pesticides in the Diets of Infants and Children by : National Research Council
Download or read book Pesticides in the Diets of Infants and Children written by National Research Council and published by National Academies Press. This book was released on 1993-02-01 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many of the pesticides applied to food crops in this country are present in foods and may pose risks to human health. Current regulations are intended to protect the health of the general population by controlling pesticide use. This book explores whether the present regulatory approaches adequately protect infants and children, who may differ from adults in susceptibility and in dietary exposures to pesticide residues. The committee focuses on four major areas: Susceptibility: Are children more susceptible or less susceptible than adults to the effects of dietary exposure to pesticides? Exposure: What foods do infants and children eat, and which pesticides and how much of them are present in those foods? Is the current information on consumption and residues adequate to estimate exposure? Toxicity: Are toxicity tests in laboratory animals adequate to predict toxicity in human infants and children? Do the extent and type of toxicity of some chemicals vary by species and by age? Assessing risk: How is dietary exposure to pesticide residues associated with response? How can laboratory data on lifetime exposures of animals be used to derive meaningful estimates of risk to children? Does risk accumulate more rapidly during the early years of life? This book will be of interest to policymakers, administrators of research in the public and private sectors, toxicologists, pediatricians and other health professionals, and the pesticide industry.
Author :IARC Working Group on the Evaluation of Carcinogenic Risks to Humans Publisher :World Health Organization ISBN 13 :9789283201502 Total Pages :0 pages Book Rating :4.2/5 (15 download)
Book Synopsis Some Organophosphate Insecticides and Herbicides by : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
Download or read book Some Organophosphate Insecticides and Herbicides written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by World Health Organization. This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of the IARC Monographs provides evaluations of the carcinogenicity of some organophosphate insecticides and herbicides, including diazinon, glyphosate, malathion, parathion, and tetrachlorvinphos. Diazinon acts on a wide range of insects on crops, gardens, livestock, and pets, but most uses have been restricted in the USA, Canada, and the European Union since the 1980s. Glyphosate is the most heavily used agricultural and residential herbicide in the world, and has been detected in soil, air, surface water, and groundwater, as well as in food. Malathion is one of the oldest and most widely used organophosphate insecticides, and has a broad spectrum of applications in agriculture and public health, notably mosquito control. The insecticide parathion has been largely banned or restricted throughout the world due to toxicity to wildlife and humans. Tetrachlorvinphos is banned in the European Union, but continues to be used in the USA and elsewhere as an insecticide on animals, including in pet flea collars. The IARC Monographs Working Group reviewed epidemiological evidence, animal bioassays, and mechanistic and other relevant data to reach conclusions as to the carcinogenic hazard to humans of these agents.
Book Synopsis Pesticides in Crop Production by : Prabhat Kumar Srivastava
Download or read book Pesticides in Crop Production written by Prabhat Kumar Srivastava and published by John Wiley & Sons. This book was released on 2020-04-27 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to the diversity of pesticides used in modern agricultural practices, and the relevant social and environmental issues Pesticides in Crop Production offers an important resource that explores pesticide action in plants; pesticide metabolism in soil microbes, plants and animals; bioaccumulation of pesticides and sensitiveness of microbiome towards pesticides. The authors explore pesticide risk assessment, the development of pesticide resistance in pests, microbial remediation of pesticide intoxicated legumes and pesticide toxicity amelioration in plants by plant hormones. The authors include information on eco-friendly pest management. They review the impact of pesticides on soil microorganism, crops and other plants along with the impact on other organisms like aquatic fauna and terrestrial animals including human beings. The book also contains an analysis of pesticide by GC-MS/MS (Gas Chromatography tandem Mass Spectrometry) a reliable method for the quantification and confirmation of multiclass pesticide residues. This important book: Offers a comprehensive guide to the use of the diversity of pesticides and the pertinent social and environmental issues Explores the impact of pesticides from morphological, anatomical, physiological and biochemical perspectives Shows how pesticides affects soil microorganisms, crops and other plants along with the impact on other organisms like aquatic fauna and animals Critically examines whether chemical pesticides are boon or bane and whether they can be replaced by environmental friendly pesticides Written for students, researchers and professionals in agriculture, botany, entomology and biotechnology, Pesticides in Crop Production examines the effects of chemical pesticides and the feasibility of using bio-pesticides.
Book Synopsis Mode of Action, Metabolism and Toxicology by : S. Matsunaka
Download or read book Mode of Action, Metabolism and Toxicology written by S. Matsunaka and published by Elsevier. This book was released on 2013-10-22 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pesticide Chemistry: Human Welfare and the Environment, Volume 3: Mode of Action, Metabolism and Toxicology covers the proceeding of the Fifth International Congress of Pesticide Chemistry. This book is organized into three parts that tackle relevant issues regarding the use of pesticide. The opening part tackles topics relevant to the biochemistry of pests and mode of action of pesticides, such as influence of chlorinated and parathyroid insecticide on cellular calcium regulatory mechanisms; behavioral and lethal actions of amidines on invertebrates; and insect chitin synthetase as biochemical probe for insecticidal compounds. The second part encompasses metabolism and degradation of pesticides and xenobiotics and includes topics on propesticides; selective toxicity conferred by activation; and comparative biochemistry of animal, plant, and microorganism oxidases. The last part covers the toxicology of pesticides and xenobiotics, including the role of biochemical studies in modern toxicological assessment of pesticides; neurophysiological and behavioral assessment of pesticide toxicity; and genetic toxicology applied to the assessment of mutagenic, carcinogenic, and teratogenic action of pesticides and related compounds. This book will be of great interest to chemists, biologists, botanists, and entomologists or professionals whose line of work involves the use of pesticides and who are concerned with pesticide side-effects to the users and the environment.
Book Synopsis Fate of Pesticides in Large Animals by : American Chemical Society. Division of Pesticide Chemistry
Download or read book Fate of Pesticides in Large Animals written by American Chemical Society. Division of Pesticide Chemistry and published by . This book was released on 1977 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fate of Pesticides in Large Animals ...
Book Synopsis Pesticide Chemistry and Toxicology by : Dileep K. Singh
Download or read book Pesticide Chemistry and Toxicology written by Dileep K. Singh and published by Bentham Science Publishers. This book was released on 2012-01-30 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pesticide control involves killing pest organisms or otherwise preventing them from destructive behavior. Pesticides are either natural or synthetic and are applied to target pests in a myriad of formulations (EC,WP, SP, FP, G etc.) and application technology systems (sprays, baits, slow-release diffusion, dust, etc.). In recent years, the bacterial genes coding for insecticidal proteins have been incorporated into various crops that dealt with the mortality of the pests feeding on them. Many other eco-friendly methods for insect pest control such as Integrated Pest Management (IPM), use of bio-pesticides etc., are becoming popular. Bio-pesticides and IPM should show good growth in the future, as there is growing concern for the eco-friendly organic agriculture and could be achieved through Good Agriculture Practices (GAP). Use of pesticides requires a proper understanding of the chemistry, their handling and their use in crop protection or hygiene. These are toxic chemicals and require a good understanding of therapy and antidotes at the time of poisoning. This e-book covers pesticide chemistry, metabolic/degradation pathways, biochemical toxicology, therapy and antidotes, nano-pesticides and terminologies associated with pesticide toxicology. the book should serve as a text book for academia, or as a reference work for agriculturists, environmentalists and industry professionals.
Book Synopsis Metabolic Pathways of Agrochemicals by : Terry R Roberts
Download or read book Metabolic Pathways of Agrochemicals written by Terry R Roberts and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 872 pages. Available in PDF, EPUB and Kindle. Book excerpt: This important publication provides a comprehensive summary of data and information on the metabolism and chemical degradation of agrochemicals in soils, plants and animals. Part 1, Herbicides and Plant Growth Regulators, and Part 2, Insecticides and Fungicides, together provide a major bibliography, as each entry is fully referenced. Contents include metabolic products, pathways and mechanisms, together with useful details on physico-chemical properties and mode of action. Both parts are organised by class of chemical for easy reference. There are separate entries for each pesticide, covering most commercially available chemicals in use today. In addition, an overview of the metabolism of each major class provides the reader with an informed summary of key similarities and significant differences between individual chemicals. Information is based primarily on literature from the past 40 years of research, together with some important, previously unpublished work provided by the agrochemical companies. Presented in a systematic, easy-to-read style, with extensive indexing to facilitate the rapid location of required information and the comparison of related compounds, Metabolic Pathways of Agrochemicals is an invaluable reference for chemists, biochemists and biologists working in the discovery, development and registration of agrochemicals, as well as scientists in related areas such as design and mode of action of pharmaceuticals.
Book Synopsis The Toxicology and Biochemistry of Insecticides by : Simon J. Yu
Download or read book The Toxicology and Biochemistry of Insecticides written by Simon J. Yu and published by CRC Press. This book was released on 2011-03-05 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first book in two decades to address this multi-faceted field, The Toxicology and Biochemistry of Insecticides provides the most up-to-date information on insecticide classification, formulation, mode of action, resistance, metabolism, environmental fate, and regulatory legislation. The book draws on the author's groundbreaking research
Book Synopsis Perils of Pesticides by : Mukund Joshi
Download or read book Perils of Pesticides written by Mukund Joshi and published by Foundation Books. This book was released on 2005 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: This concise book is intended to create public awareness about aspects of pesticide use in India. Ignorance about pesticides in India is widespread and administrative and legislative lacunae have aggravated the situation. This book is a small step in the long and ardous process of helping to make our society and environment pesticide free.
Book Synopsis Pesticide Impact on Fish Metabolism by : K.R.S. Rao
Download or read book Pesticide Impact on Fish Metabolism written by K.R.S. Rao and published by Discovery Publishing House. This book was released on 1999 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contents: Introduction, Material and Methods, Independent and Combined Toxicity of Carbaryl and Phenthoate Determination of LC50 Values and Confirmation of Synergism, Some Observations and Physical, Morphological and Behavioural Changes in Channa Punctatus, Studies on Acetylcholinesterase, Studies on whole Animal and Tissue Respiration, Studies on Some Haematological Parameters, Studies on Some Aspects of Carbohydrate Metabolism, Studies on Some Aspects of Nitrogen Metabolism, General Discussion, Summary.
Book Synopsis Pesticide Toxicology by : Eugenia Gallardo
Download or read book Pesticide Toxicology written by Eugenia Gallardo and published by . This book was released on 2022 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed volume explores practical procedures on the identification and quantification of pesticides in a variety of samples. Chapters guide the reader through methods and protocols for the extraction of pesticides from biological and non-biological samples, pitfalls in dosing techniques and structures identification, and also provide an overview of the problems that these pesticides cause in human populations. As part of the Methods in Pharmacology and Toxicology series, chapters include introductions to their respective topics, lists of reagents and materials, step-by-step guides and reproducible lab protocols, as well as valuable tips on addressing common problems and avoiding known pitfalls. Authoritative and practical, Pesticide Toxicology is an ideal reference for academia, analysts, toxicologists, environmentalists, and health and industry professionals aiming to understand the associated risks and to limit the use of these substances and minimize their potential damage to human health and the environment.
Book Synopsis Pesticide Biotransformation in Plants and Microorganisms by : J. Christopher Hall
Download or read book Pesticide Biotransformation in Plants and Microorganisms written by J. Christopher Hall and published by . This book was released on 2001 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pesticide Biotransformation in Plants and Microorganisms examines major enzymatic processes involved in pesticide transformation such as hydrolysis, oxidative and reductive metabolism, conjugation and dehalogenation in plants and microbes in the area of xenobiotic metabolism.
Book Synopsis Regulating Pesticides in Food by : National Research Council
Download or read book Regulating Pesticides in Food written by National Research Council and published by National Academies Press. This book was released on 1987-02-01 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Concern about health effects from exposure to pesticides in foods is growing as scientists learn more about the toxic properties of pesticides. The Delaney Clause, a provision of the Food, Drug and Cosmetic Act, prohibits tolerances for any pesticide that causes cancer in test animals or in humans if the pesticide concentrates in processed food or feeds. This volume examines the impacts of the Delaney Clause on agricultural innovation and on the public's dietary exposure to potentially carcinogenic pesticide residues. Four regulatory scenarios are described to illustrate the effects of varying approaches to managing oncogenic pesticide residues in food.
Download or read book Neurotoxicity of Pesticides written by and published by Academic Press. This book was released on 2020-03-21 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurotoxicity of Pesticides, Volume Four, in this comprehensive serial addresses contemporary advances in neurotoxicology of pesticides by providing authoritative review articles on key issues in the field. Edited by leading subject experts, topics of note in this new release include Organophosphates, OPs, Nerve agents, Pyrethroids, Neonicotinoids and Formamidines, among others.
Book Synopsis Metabolism of Agrochemicals in Plants by : Terence Robert Roberts
Download or read book Metabolism of Agrochemicals in Plants written by Terence Robert Roberts and published by John Wiley & Sons. This book was released on 2000-04-07 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: The importance of understanding the metabolism of agrochemicals in plants has never been greater. In a world where food safety and environmental concerns are increasing, knowledge of the metabolic processes within plants and the terminal residues of agrochemicals in food crops is invaluable. Written by experts in the agrochemical industry and academia, Metabolism of Agrochemicals in Plants is the first text to give systematic coverage of this important topic. This text brings together the current status of the subject with chapters on regulatory considerations, comparative metabolism of plants and animals, and the different phases of metabolism. Including new and novel research in primary metabolism, herbicide metabolism and bound residues, this work is unique and thoroughly up to date. This is an essential text for chemists and biochemists working in the agrochemical and pharmaceutical industries and academia as well as analytical chemists, regulatory chemists and environmental scientists. Metabolism of Agrochemicals in Plants is a volume in the Wiley Series in Agrochemicals and Plant Protection. This series brings together current scientific and regulatory knowledge and perspectives on all aspects of the use of chemicals and biotechnology in agriculture.
