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Author : Nedim Emil Altaras
Publisher :
ISBN 13 :
Total Pages : 418 pages
Book Rating : 4.:/5 (89 download)
Download or read book Metabolic Engineering for the Production of 1,2-propanediol written by Nedim Emil Altaras and published by . This book was released on 1999 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kazuyuki Shimizu
Publisher : CRC Press
ISBN 13 : 1498768385
Total Pages : 408 pages
Book Rating : 4.4/5 (987 download)
Download or read book Metabolic Regulation and Metabolic Engineering for Biofuel and Biochemical Production written by Kazuyuki Shimizu and published by CRC Press. This book was released on 2017-07-12 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: The global warming problem is becoming critical year by year, causing climate disaster all over the world, where it has been believed that the CO2 gas emitted from the factories and the burning of fossil fuels may be one of the reasons of global warming. Moreover, the global stock of fossil fuels is limited, and may run out soon within several tens of years. Although wind, geo-thermal, and tide energies have been considered as clean energy sources, those depend on the land or sea locations and subject to the climate change. Biofuel and biochemical production from renewable bio-resources has thus been paid recent attention from environmental protection and energy production points of view, where the current chemical and energy producing plants can be also utilized with slight modification. The so-called 1st generation biofuels have been produced from corn starch and sugarcane in particular in USA and Brazil. However, this causes the problem of the so-called "food and energy issues" as the production scale increases. The 2nd generation biofuel production from lingo-cellulosic biomass or wastes has thus been paid recent attention. However, it requires energy intensive pretreatment for the degradation of lingo-cellulosic biomass, and the fermentation is slow due to low growth rate, and thus the productivity of biofuels and bio-chemicals is low. The 3rd generation biofuel production from photosynthetic organisms such as cyanobacteria and algae has been also paid attention, because such organisms can grow with only sun light and CO2 in the air, but the cell growth rate and thus the productivity of the fuels is significantly low. The main part or core of such production processes is the fermentation by micro-organisms. In particular, it is critical to properly understand the cell metabolism followed by the efficient metabolic engineering. The book gives comprehensive explanation of the cell metabolism and the metabolic regulation mechanisms of a variety of micro-organisms. Then the efficient metabolic engineering approaches are explained to properly design the microbial cell factories for the efficient cell growth and biofuel and biochemical production.
Author : Stephen Van Dien
Publisher : Springer
ISBN 13 : 3319419668
Total Pages : 124 pages
Book Rating : 4.3/5 (194 download)
Download or read book Metabolic Engineering for Bioprocess Commercialization written by Stephen Van Dien and published by Springer. This book was released on 2016-07-16 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume reviews the current metabolic engineering tools and technologies from a practical point of view, and guides researchers as they overcome challenges at various stages of organism and bioprocess development. Microbes have been engineered to produce a variety of industrial products such as fuels, basic chemicals, fine chemicals, nutritional supplements, and pharmaceutical intermediates, and new tools such as gene synthesis, advanced cloning techniques, ‘omics’ analysis, and mathematical modeling have greatly accelerated the pace of innovation in the field. Written by leading experts in the field from both academia and industry, key topics include synthetic biology, pathway engineering, metabolic flux manipulation, adaptive evolution, and fermentation process scale-up. It is suitable for non-specialists, and is a valuable resource for anyone embarking on the exciting path to harnessing the metabolic potential of microorganisms.
Author : Christoph Wittmann
Publisher : Springer Science & Business Media
ISBN 13 : 9400745346
Total Pages : 391 pages
Book Rating : 4.4/5 (7 download)
Download or read book Systems Metabolic Engineering written by Christoph Wittmann and published by Springer Science & Business Media. This book was released on 2012-06-15 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systems Metabolic Engineering is changing the way microbial cell factories are designed and optimized for industrial production. Integrating systems biology and biotechnology with new concepts from synthetic biology enables the global analysis and engineering of microorganisms and bioprocesses at super efficiency and versatility otherwise not accessible. Without doubt, systems metabolic engineering is a major driver towards bio-based production of chemicals, materials and fuels from renewables and thus one of the core technologies of global green growth. In this book, Christoph Wittmann and Sang-Yup Lee have assembled the world leaders on systems metabolic engineering and cover the full story – from genomes and networks via discovery and design to industrial implementation practises. This book is a comprehensive resource for students and researchers from academia and industry interested in systems metabolic engineering. It provides us with the fundaments to targeted engineering of microbial cells for sustainable bio-production and stimulates those who are interested to enter this exiting research field.
Author : Sang Yup Lee
Publisher : John Wiley & Sons
ISBN 13 : 352782345X
Total Pages : 1075 pages
Book Rating : 4.5/5 (278 download)
Download or read book Metabolic Engineering written by Sang Yup Lee and published by John Wiley & Sons. This book was released on 2021-06-02 with total page 1075 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn more about foundational and advanced topics in metabolic engineering in this comprehensive resource edited by leaders in the field Metabolic Engineering: Concepts and Applications delivers a one-stop resource for readers seeking a complete description of the concepts, models, and applications of metabolic engineering. This guide offers practical insights into the metabolic engineering of major cell lines, including E. Coli, Bacillus and Yarrowia Lipolytica, and organisms, including human, animal, and plant). The distinguished editors also offer readers resources on microbiome engineering and the use of metabolic engineering in bioremediation. Written in two parts, Metabolic Engineering begins with the essential models and strategies of the field, like Flux Balance Analysis, Quantitative Flux Analysis, and Proteome Constrained Models. It also provides an overview of topics like Pathway Design, Metabolomics, and Genome Editing of Bacteria and Eukarya. The second part contains insightful descriptions of the practical applications of metabolic engineering, including specific examples that shed light on the topics within. In addition to subjects like the metabolic engineering of animals, humans, and plants, you’ll learn more about: Metabolic engineering concepts and a historical perspective on their development The different modes of analysis, including flux balance analysis and quantitative flux analysis An illuminating and complete discussion of the thermodynamics of metabolic pathways The Genome architecture of E. coli, as well as genome editing of both bacteria and eukarya An in-depth treatment of the application of metabolic engineering techniques to organisms including corynebacterial, bacillus, and pseudomonas, and more Perfect for students of biotechnology, bioengineers, and biotechnologists, Metabolic Engineering: Concepts and Applications also has a place on the bookshelves of research institutes, biotechnological institutes and industry labs, and university libraries. It's comprehensive treatment of all relevant metabolic engineering concepts, models, and applications will be of use to practicing biotechnologists and bioengineers who wish to solidify their understanding of the field.
Author : Michael L. Hoffman
Publisher :
ISBN 13 :
Total Pages : 470 pages
Book Rating : 4.:/5 (89 download)
Download or read book Metabolic Engineering of 1,2-Propanediol Production in Saccharomyces Cerevisiae written by Michael L. Hoffman and published by . This book was released on 1999 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Yebo Li
Publisher : John Wiley & Sons
ISBN 13 : 1118568362
Total Pages : 601 pages
Book Rating : 4.1/5 (185 download)
Download or read book Bioenergy written by Yebo Li and published by John Wiley & Sons. This book was released on 2016-09-15 with total page 601 pages. Available in PDF, EPUB and Kindle. Book excerpt: BIOENERGY: PRINCIPLES AND APPLICATIONS BIOENERGY: PRINCIPLES AND APPLICATIONS With growing concerns over climate change and energy insecurity coupled with dwindling reserves of fossil energy resources, there is a growing search for alternative, renewable energy resources. Energy derived from renewable bioresources such as biomass (energy crops, agri- and forest residues, algae, and biowastes) has received significant attention in recent years. With the growing interest in bioenergy, there has been increasing demand for a broad-ranging, introductory textbook that provides an essential overview of this very subject to students in the field. Bioenergy: Principles and Applications offers an invaluable introduction to both fundamental and applied aspects of bioenergy feedstocks and their processing, as well as lifecycle and techno-economic analyses, and policies as applied to bioenergy. Bioenergy: Principles and Applications provides readers with foundational information on first-, second-, and third-generation bioenergy, ranging from plant structure, carbohydrate chemistry, mass and energy balance, thermodynamics, and reaction kinetics to feedstock production, logistics, conversion technologies, biorefinery, lifecycle and techno-economic analyses, and government policies. This textbook gives students and professionals an incomparable overview of the rapidly growing field of bioenergy. Bioenergy: Principles and Applications will be an essential resource for students, engineers, researchers, and industry personnel interested in, and working in, the bioenergy field.
Author : Vipin Chandra Kalia
Publisher : Springer
ISBN 13 : 9811055114
Total Pages : 413 pages
Book Rating : 4.8/5 (11 download)
Download or read book Metabolic Engineering for Bioactive Compounds written by Vipin Chandra Kalia and published by Springer. This book was released on 2017-10-07 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book comprehensively discusses the latest research in the area of metabolic engineering. Metabolic engineering solutions for bioactive compounds are now being derived by means of heterologous gene expression, in a wide range of organisms. The book provides an overview of the model systems being employed for metabolic manipulation to yield bioactive molecules, such as single-cell proteins, antibody generation, metabolites, proteases, chaperones, therapeutic proteins, nanomaterials, polymeric conjugates, dendrimers and nanoassemblies, Escherichia coli, Agrobacterium, Saccharomyces cerevisiae and cell lines, etc. In addition, it shares insights into the scope of these methods in the areas of prevention, diagnosis and treatment of diseases, e.g. immunotherapy for curing various diseases like cancer, allergies, autoimmune diseases, etc.
Author : Paul Hudson
Publisher : John Wiley & Sons
ISBN 13 : 352782491X
Total Pages : 560 pages
Book Rating : 4.5/5 (278 download)
Download or read book Cyanobacteria Biotechnology written by Paul Hudson and published by John Wiley & Sons. This book was released on 2021-04-20 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unites a biological and a biotechnological perspective on cyanobacteria, and includes the industrial aspects and applications of cyanobacteria Cyanobacteria Biotechnology offers a guide to the interesting and useful features of cyanobacteria metabolism that keeps true to a biotechnology vision. In one volume the book brings together both biology and biotechnology to illuminate the core acpects and principles of cyanobacteria metabolism. Designed to offer a practical approach to the metabolic engineering of cyanobacteria, the book contains relevant examples of how this metabolic "module" is currently being engineered and how it could be engineered in the future. The author includes information on the requirements and real-world experiences of the industrial applications of cyanobacteria. This important book: Brings together biology and biotechnology in order to gain insight into the industrial relevant topic of cyanobacteria Introduces the key aspects of the metabolism of cyanobacteria Presents a grounded, practical approach to the metabolic engineering of cyanobacteria Offers an analysis of the requirements and experiences for industrial cyanobacteria Provides a framework for readers to design their own processes Written for biotechnologists, microbiologists, biologists, biochemists, Cyanobacteria Biotechnology provides a systematic and clear volume that brings together the biological and biotechnological perspective on cyanobacteria.
Author : Nami Tatsumi
Publisher : Springer Science & Business Media
ISBN 13 : 3642298575
Total Pages : 415 pages
Book Rating : 4.6/5 (422 download)
Download or read book Corynebacterium glutamicum written by Nami Tatsumi and published by Springer Science & Business Media. This book was released on 2012-08-14 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: Corynebacterium glutamicum was discovered in Japan in 1956 as a natural glutamate producer. Its “microbial factory” qualities, such as its physiological plasticity and robust catalytic functionalities, have since facilitated the development of efficient production processes for amino acids, nucleotides and vitamins. This monograph illustrates how the information gleaned from complete genome sequencing allows the rational engineering of the entire cellular metabolism and how systems biology permits the further optimization of C. glutamicum as a biocatalyst. Aspects of gene regulation, metabolic pathways, sugar uptake, protein secretion, cell division and biorefinery applications highlight the enormous biotechnological and biorefinery potential.
Author : Vipin Chandra Kalia
Publisher : Springer
ISBN 13 : 8132225988
Total Pages : 353 pages
Book Rating : 4.1/5 (322 download)
Download or read book Microbial Factories written by Vipin Chandra Kalia and published by Springer. This book was released on 2016-02-16 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the efforts made by distinguished scientific researchers world-wide to meet two key challenges: i) the limited reserves of polluting fossil fuels, and ii) the ever-increasing amounts of waste being generated. These case studies have brought to the foreground certain innovative biological solutions to real-life problems we now face on a global scale: environmental pollution and its role in deteriorating human health. The book also highlights major advances in microbial metabolisms, which can be used to produce bioenergy, biopolymers, bioactive molecules, enzymes, etc. Around the world, countries like China, Germany, France, Sweden and the US are now implementing major national programs for the production of biofuels. The book provides information on how to meet the chief technical challenges – identifying an industrially robust microbe and cheap raw material as feed. Of the various possibilities for generating bioenergy, the most attractive is the microbial production of biohydrogen, which has recently gained significant recognition worldwide, due to its high efficiency and eco-friendly nature. Further, the book highlights factors that can make these bioprocesses more economical, especially the cost of the feed. The anaerobic digestion (AD) process is more advantageous in comparison to aerobic processes for stabilizing biowastes and producing biofuels (hydrogen, biodiesel, 1,3-propanediol, methane, electricity), biopolymers (polyhydroxyalkanoates, cellulose, exopolysaccharides) and bioactive molecules (such as enzymes, volatile fatty acids, sugars, toxins, etc.) for biotechnological and medical applications. Information is provided on how the advent of molecular biological techniques can provide greater insights into novel microbial lineages. Bioinformatic tools and metagenomic techniques have extended the limits to which these biological processes can be exploited to improve human welfare. A new dimension to these scientific works has been added by the emergence of synthetic biology. The Big Question is: How can these Microbial Factories be improved through metabolic engineering and what cost targets need to be met?
Author : Sunita Varjani
Publisher : Elsevier
ISBN 13 : 0323910467
Total Pages : 674 pages
Book Rating : 4.3/5 (239 download)
Download or read book Biomass, Biofuels, Biochemicals written by Sunita Varjani and published by Elsevier. This book was released on 2021-12-04 with total page 674 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomass, Biofuels, Biochemicals: Circular Bioeconomy: Technologies for Biofuels and Biochemicals provides comprehensive information on strategies and approaches that facilitate the integration of technologies for the production of bio-based fuels, chemicals and other value-added products from wastes with waste biorefinery concepts and green strategies. The book also covers lifecycle assessment and techno-economic analyses of integrated biorefineries within a circular bioeconomy framework. As there has been continual research on new designs in production and consumerist approaches as we move towards sustainable development by scientists of various disciplines, law makers, environmental activists and industrialists, this book provides the latest details. Resources consumption and environment degradation necessitates a transition of our linear economy towards sustainable social and technical systems. As fossil resources are only projected to fulfill the needs of the population for the next couple of centuries, new tactics and standards must be created to ensure future success. - Covers recent developments and perspectives on biofuels and chemicals production - Provides the latest on the integration of technologies and processes for biofuels and chemicals production - Paves a way forward roadmap to achieve Sustainable Development Goals - Covers recent developments in lifecycle assessment and techno economic analysis using a waste biorefinery approach
Author : George Stephanopoulos
Publisher : Elsevier
ISBN 13 : 008053628X
Total Pages : 749 pages
Book Rating : 4.0/5 (85 download)
Download or read book Metabolic Engineering written by George Stephanopoulos and published by Elsevier. This book was released on 1998-10-17 with total page 749 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolic engineering is a new field with applications in the production of chemicals, fuels, materials, pharmaceuticals, and medicine at the genetic level. The field's novelty is in the synthesis of molecular biology techniques and the tools of mathematical analysis, which allow rational selection of targets for genetic modification through measurements and control of metabolic fluxes. The objective is to identify specific genetics or environmental manipulations that result in improvements in yield and productivities of biotechnological processes. Key features of the book are pathway integration and the focus on metabolic flux as a fundamental determinant of cell physiology. The book keeps mathematical complexity to a minimum, and provides a glossary of biological terms to facilitate use of the book by a broader spectrum of readers. A web page exists to communicate updates of the codes and homework problems. - Demonstrates metabolic engineering in action with numerous examples of pathway modification - Includes methods for identifying key enzymes in metabolic networks - Contains a comprehensive review of metabolic biochemistry - Discusses metabolic regulation at the gene, enzyme, operon, and cell levels - Explains concepts of stoichiometry, kinetics, and thermodynamics of metabolic pathways - Minimizes mathematical complexity - Links to a Web page to communicate updates of the software code and homework problems
Author : Rodrigo Ledesma-Amaro
Publisher : Frontiers Media SA
ISBN 13 : 2889637085
Total Pages : 142 pages
Book Rating : 4.8/5 (896 download)
Download or read book Synthetic Biology-Guided Metabolic Engineering written by Rodrigo Ledesma-Amaro and published by Frontiers Media SA. This book was released on 2020-05-05 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Author :
Publisher : Elsevier
ISBN 13 : 0323955622
Total Pages : 450 pages
Book Rating : 4.3/5 (239 download)
Download or read book Biochemical Pathways and Environmental Responses in Plants: Part A written by and published by Elsevier. This book was released on 2022-10-22 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemical Pathways and Environmental Responses in Plants, Part A, Volume 676 in the Methods in Enzymology series highlights new advances in the field with this new volume presenting interesting chapters on topics such as Structure, function, and engineering of plant polyketide synthases, A sensitive LC-MS/MS assay for enzymatic characterization of methylthioalkylmalate synthase involved in glucosinolate side-chain elongation, Assaying formate-tetrahydrofolate ligase with monoglutamylated and polyglutamylated substrates using a fluorescence-HPLC based assay, An Approach to Nearest Neighbor Analysis of Pigmented Protein Complexes by Using Chemical Crosslinking in Combination with Mass Spectrometry, and much more. Other chapters cover Biochemical characterization of plant aromatic aminotransferases, Functional Analysis of Phosphoethanolamine N-methyltransferase (PMT) in Plants and Parasites, A structure-guided computational screening approach for predicting plant enzyme-metabolite interactions, Plant metacaspase: an example of microcrystal structure determination and analysis, Biocatalytic system for comparative assessment of functional association of cytochrome P450 monooxygenases with their redox partners, Dirigent Protein Family Function and Structure, and more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in Methods in Enzymology series - Includes the latest information on Biochemical pathways and environmental responses in plants
Author : Guillermo Gosset
Publisher : Springer
ISBN 13 : 3319517295
Total Pages : 203 pages
Book Rating : 4.3/5 (195 download)
Download or read book Engineering of Microorganisms for the Production of Chemicals and Biofuels from Renewable Resources written by Guillermo Gosset and published by Springer. This book was released on 2017-01-26 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews state of the art regarding strategies for generating and improving microbial strains designed for utilizing renewable raw materials. It discusses methods for genetically engineering of thermophilic bacteria, Saccharomyces cerevisiae, Escherichia coli and Zymomonas mobilis, as well as approaches for obtaining useful products from these renewable raw materials based on biotechnological processes using microbes to chemically transform them. However, the efficient transformation of lignocellulosic biomass or glycerol to useful products represents a major challenge: Biomass has to be treated physically and chemically to release a mixture of sugars that potentially can be employed by the microbial production strains. These hydrolytic treatments result in diverse toxic compounds being generated and released, that negatively impact strain performance. Furthermore, most of the commonly used industrial microbes do not have the natural capacity to efficiently utilize and transform the generated sugar mixtures or glycerol. The microbial species reviewed in this book possess particular advantages as production strains and are currently employed for the synthesis of numerous biofuels and chemicals. The book reviews the general and strain-specific genetic engineering strategies for the improvement of sugar mixtures and glycerol catabolism. The issue of lignocellulosic hydrolysate toxicity is addressed in several chapters, where genetic engineering and adaptive laboratory evolution strategies are reviewed and discussed. The objective of this book is to provide the current knowledge regarding strategies for the generation and improvement of microbial strains designed for the transformation of renewable raw materials into useful products. This book aims to become a reference for researchers and students working in this field.
Author : Paul Hudson
Publisher : John Wiley & Sons
ISBN 13 : 3527824928
Total Pages : 560 pages
Book Rating : 4.5/5 (278 download)
Download or read book Cyanobacteria Biotechnology written by Paul Hudson and published by John Wiley & Sons. This book was released on 2021-04-20 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unites a biological and a biotechnological perspective on cyanobacteria, and includes the industrial aspects and applications of cyanobacteria Cyanobacteria Biotechnology offers a guide to the interesting and useful features of cyanobacteria metabolism that keeps true to a biotechnology vision. In one volume the book brings together both biology and biotechnology to illuminate the core acpects and principles of cyanobacteria metabolism. Designed to offer a practical approach to the metabolic engineering of cyanobacteria, the book contains relevant examples of how this metabolic "module" is currently being engineered and how it could be engineered in the future. The author includes information on the requirements and real-world experiences of the industrial applications of cyanobacteria. This important book: Brings together biology and biotechnology in order to gain insight into the industrial relevant topic of cyanobacteria Introduces the key aspects of the metabolism of cyanobacteria Presents a grounded, practical approach to the metabolic engineering of cyanobacteria Offers an analysis of the requirements and experiences for industrial cyanobacteria Provides a framework for readers to design their own processes Written for biotechnologists, microbiologists, biologists, biochemists, Cyanobacteria Biotechnology provides a systematic and clear volume that brings together the biological and biotechnological perspective on cyanobacteria.
