Membrane Defenses Against Attack by Complement and Perforins

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Publisher : Springer
ISBN 13 : 9783642770159
Total Pages : 188 pages
Book Rating : 4.7/5 (71 download)

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Book Synopsis Membrane Defenses Against Attack by Complement and Perforins by : Charles J. Parker

Download or read book Membrane Defenses Against Attack by Complement and Perforins written by Charles J. Parker and published by Springer. This book was released on 2011-12-27 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this volume a comprehensive review of membrane proteins that regulate complement and perforin-mediated cytolysis is presented. A detailed analysisis provided of the biochemical, molecular, and functional features of these proteins; the glycosyl phosphatidylinositol linked proteins are covered, with emphasis placed on the functional importance of this type of membrane anchor. Further chapters include reviews of the effects of complement activation on cells that are metabolically active, and of the regulation of cell killing by cytotoxic lymphocytes, considering the similarities and disparities between the complement and perforin systems. The therapeutic use of recombinant CR1 for immune-mediated pathophysiological processes is discussed in a separate section.

Membrane Defenses Against Attack by Complement and Perforins

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Publisher : Springer Science & Business Media
ISBN 13 : 3642770142
Total Pages : 193 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Membrane Defenses Against Attack by Complement and Perforins by : Charles J. Parker

Download or read book Membrane Defenses Against Attack by Complement and Perforins written by Charles J. Parker and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this volume a comprehensive review of membrane proteins that regulate complement and perforin-mediated cytolysis is presented. A detailed analysisis provided of the biochemical, molecular, and functional features of these proteins; the glycosyl phosphatidylinositol linked proteins are covered, with emphasis placed on the functional importance of this type of membrane anchor. Further chapters include reviews of the effects of complement activation on cells that are metabolically active, and of the regulation of cell killing by cytotoxic lymphocytes, considering the similarities and disparities between the complement and perforin systems. The therapeutic use of recombinant CR1 for immune-mediated pathophysiological processes is discussed in a separate section.

The Complement System

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Publisher : Springer Science & Business Media
ISBN 13 : 3642587534
Total Pages : 580 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis The Complement System by : K. Rother

Download or read book The Complement System written by K. Rother and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of the former editions remains unchanged in the present updated version, namely to put forward a general and comprehensive review on complement. It is intended not only for individual investigators working in this specific field, but also for those who are less familiar with it. Students or younger scientists will hopefully be stimulated and attracted by the fascination of complement biology. Again, it was clear from the beginning that the field has experienced an explosive expansion in various directions and continues to accumulate data too large to be dealt with by a single author in a critical and coherent manner. The editors are grateful that the invited authors, all of them leading scientists in their field, helped again to make The Complement System a true mirror of the state of the art. Some parallels in the various chapters were accepted, as was a particular emphasis on newer developments in some chapters.

National Library of Medicine Current Catalog

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Publisher :
ISBN 13 :
Total Pages : 1328 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis National Library of Medicine Current Catalog by : National Library of Medicine (U.S.)

Download or read book National Library of Medicine Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1993 with total page 1328 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Immunochemistry

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Publisher : CRC Press
ISBN 13 : 9780824791230
Total Pages : 1092 pages
Book Rating : 4.7/5 (912 download)

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Book Synopsis Immunochemistry by : Vanoss

Download or read book Immunochemistry written by Vanoss and published by CRC Press. This book was released on 1994-08-24 with total page 1092 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work offers comprehensive coverage of the chemical and physicochemical aspects of immunological interactions, as well as the molecules and moieties involved in these interactions. It covers in detail the Ag-Ab interaction, including attraction at a distance between epitope and paratope. College or university bookstores may order five or more copies at a special student price, available upon request.

Complement Regulatory Proteins

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Publisher : Academic Press
ISBN 13 : 9780080529561
Total Pages : 382 pages
Book Rating : 4.5/5 (295 download)

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Book Synopsis Complement Regulatory Proteins by : B. Paul Morgan

Download or read book Complement Regulatory Proteins written by B. Paul Morgan and published by Academic Press. This book was released on 1999-02-18 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: From small beginnings in the early 1970s, the study of complement regulatory proteins has grown in the last decade to the point where it dominates the complement field. This growth has been fueled by the discovery of new regulators, the cloning of old and new regulators, the discovery that many of the regulators are structurally and evolutionarily related to each other and the development of recombinant forms for use in therapy. There are now more proteins known to be involved in controlling the complement system than there are components of the system and the list continues to grow. The time is ripe for a comprehensive review of our current knowledge of these intriguing proteins. This book does just that. The first few chapters discuss the "nuts-and-bolts" of the complement regulators, describing their structures, functional roles and modes of action. The roles of the complement regulators in vivo are then described, focusing on the consequences of deficiency, roles in the reproductive system, interactions with pathogens and exploitation for therapy. The interesting developments in defining the complement regulators expressed in other species are also discussed. The book is written as a monograph, albeit by two people. The text is as readable as possible without compromising on scientific accuracy and completeness. The conversational style very evident in some sections is deliberate! Placing all references in a single bibliography at the end of the text further improves readability. The reader will go to the book to discover a specific fact but be persuaded to read more and derive pleasure from the process. The authors' enthusiasm for the subject comes over strongly in the text, and this enthusiasm proves infectious. Complement regulators--structure, functional roles and mode of action Comprehensive reviews of each of the individual regulators Roles of Complement regulators in vivo,in health and disease: Consequences of deficiency Roles in the reproductive system Interactions with pathogens Exploitation for therapy Complement regulators in other species

Breast Cancer Updates

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 1803559306
Total Pages : 308 pages
Book Rating : 4.8/5 (35 download)

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Book Synopsis Breast Cancer Updates by : Selim Sözen

Download or read book Breast Cancer Updates written by Selim Sözen and published by BoD – Books on Demand. This book was released on 2023-05-03 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Lupus

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Publisher : Springer Science & Business Media
ISBN 13 : 1592597033
Total Pages : 727 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Lupus by : Gary M. Kammer

Download or read book Lupus written by Gary M. Kammer and published by Springer Science & Business Media. This book was released on 1999-05-04 with total page 727 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading basic and clinical investigators from around the world summarize the most recent research on the molecular and cellular origins of lupus. Their cutting-edge articles review the mechanisms underlying abnormal immunity and introduce the powerful new concept that a disorder of multiple genes underlies the abnormal immune response, leading directly to the development of lupus. This pathophysiology is shown to involve a wide variety of cell types, including T cells, B cells, natural killer cells, macrophages/monocytes, and endothelial cells. Over time, the resulting long-term inflammation causes irreversible cell destruction and, ultimately, organ failure. Lupus: Molecular and Cellular Pathogenesis is a masterful new synthesis of all the new knowledge emerging today about lupus. Its new perspectives will sharpen the focus of research and ultimately lead to better and more effective treatment.

Janeway's Immunobiology

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Author :
Publisher : Garland Science
ISBN 13 : 9780815344575
Total Pages : pages
Book Rating : 4.3/5 (445 download)

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Book Synopsis Janeway's Immunobiology by : Kenneth Murphy

Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

MACPF/CDC Proteins - Agents of Defence, Attack and Invasion

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Author :
Publisher : Springer
ISBN 13 : 9401788812
Total Pages : 329 pages
Book Rating : 4.4/5 (17 download)

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Book Synopsis MACPF/CDC Proteins - Agents of Defence, Attack and Invasion by : Gregor Anderluh

Download or read book MACPF/CDC Proteins - Agents of Defence, Attack and Invasion written by Gregor Anderluh and published by Springer. This book was released on 2014-05-05 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focusses on evolutionary, structural and functional aspects of pore-forming proteins, bringing together prominent researchers in the fields of structural biology and cellular and biophysical techniques. The focus is on the MACPF/CDC protein super family that was originally discovered because of unexpected structural similarity between a domain present in bacterial cholesterol-dependent cytolysins (CDC) and proteins of the membrane attack complex/perforin (MACPF) family. Members of the MACPF/CDC super family are crucial for many biological processes, being efficient agents of development, defence, attack and invasion of cells and tissues. However, their best-known role is in bacterial pathogenesis and the proper functioning of the vertebrate immune system, via formation of transmembrane pores in target cell membranes. The book contains chapters on the distribution of MACPF/CDC proteins and on aspects of their evolution and structural properties, the similarities between different super family members and functional properties of some of the best known examples. The book also contains an overview of biophysical approaches that may be used in the future to provide further insights into how these interesting proteins function.

Current Catalog

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Publisher :
ISBN 13 :
Total Pages : 1628 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Current Catalog by : National Library of Medicine (U.S.)

Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1993 with total page 1628 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.

Immunobiology

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Publisher : Elsevier
ISBN 13 : 9780080534497
Total Pages : 336 pages
Book Rating : 4.5/5 (344 download)

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Book Synopsis Immunobiology by : Edward Bittar

Download or read book Immunobiology written by Edward Bittar and published by Elsevier. This book was released on 1996-12-17 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: As this volume demonstrates, immunobiology is a young science which is undergoing explosive growth. Judged by results, it is already an elaborate discipline which cuts across every other area in biomedical research and even has its own vocabolary (e.g., the "veto" effect). Rather than inculcate the habit of superficial learning by having the student go through a maze of details, we have sought to gather together sixteen essays that range from T-cells to psyhoneuroimmunology. This is keeping with the growing understanding that the student is expected to read and think far more for herself/himself. Next to nothing is known about innate immunity. However, recent evidence suggests that collectins might bridge the gap between innate immunity and specific clonal immune responses. Collectins are soluble effector proteins that include serum mannose-binding protein, and lung surfactants A and D. They are considered to be ante-antibodies.

Kelley's Textbook of Rheumatology E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 1455737674
Total Pages : 2345 pages
Book Rating : 4.4/5 (557 download)

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Book Synopsis Kelley's Textbook of Rheumatology E-Book by : Gary S. Firestein

Download or read book Kelley's Textbook of Rheumatology E-Book written by Gary S. Firestein and published by Elsevier Health Sciences. This book was released on 2012-08-31 with total page 2345 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kelley's Textbook of Rheumatology delivers the state-of-the-art scientific and clinical know-how you need to offer your patients the most effective diagnosis and care. This rheumatology book’s sweeping updates highlight current advances and breakthroughs that impact your practice. With Kelley's Textbook of Rheumatology, you'll be ready to handle the toughest clinical challenges you face. Search the entire contents online at www.expertconsult.com, download all of images, and watch videos demonstrating the complete musculoskeletal exam, including abnormal findings and the arthroscopic presentation of diseased joints. Review basic science advances and their clinical implications in one place and get dependable, evidence-based guidance with the integrated chapter format that readers of Kelley's Textbook of Rheumatology have always appreciated. Gain a thorough understanding of the "whys" and "hows" of rheumatic disease management with detailed coverage of the very latest breakthroughs and the newest clinical algorithms. Apply the latest therapeutic advances through new chapters in bioengineering and tissue engineering, as well as up-to-date coverage of gout and disease-modifying drugs. Learn how the study of biomarkers across populations can help you detect diseases earlier and with greater accuracy with a new chapter on epigenetics. Diagnose, monitor, and manage rheumatic disease more effectively with expanded information on the use of ultrasound and other imaging modalities.

Current Topics in Membranes and Transport

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Publisher : Academic Press
ISBN 13 : 9780080585079
Total Pages : 181 pages
Book Rating : 4.5/5 (85 download)

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Book Synopsis Current Topics in Membranes and Transport by :

Download or read book Current Topics in Membranes and Transport written by and published by Academic Press. This book was released on 1990-08-10 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current Topics in Membranes and Transport

Perforins and Cholesterol-Dependent Cytolysins in Immunity and Pathogenesis

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Publisher : Frontiers Media SA
ISBN 13 : 2889762173
Total Pages : 192 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Perforins and Cholesterol-Dependent Cytolysins in Immunity and Pathogenesis by : George P. Munson

Download or read book Perforins and Cholesterol-Dependent Cytolysins in Immunity and Pathogenesis written by George P. Munson and published by Frontiers Media SA. This book was released on 2022-07-25 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular Biology of The Cell

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Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of The Cell by : Bruce Alberts

Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Ciência E Cultura

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Publisher :
ISBN 13 :
Total Pages : 420 pages
Book Rating : 4.A/5 ( download)

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Book Synopsis Ciência E Cultura by :

Download or read book Ciência E Cultura written by and published by . This book was released on 1994 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: