Medicinal Chemistry Iii

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Comprehensive Medicinal Chemistry III

Author :
Publisher : Elsevier
ISBN 13 : 0128032014
Total Pages : 4609 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Comprehensive Medicinal Chemistry III by :

Download or read book Comprehensive Medicinal Chemistry III written by and published by Elsevier. This book was released on 2017-06-03 with total page 4609 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Medicinal Chemistry III, Eight Volume Set provides a contemporary and forward-looking critical analysis and summary of recent developments, emerging trends, and recently identified new areas where medicinal chemistry is having an impact. The discipline of medicinal chemistry continues to evolve as it adapts to new opportunities and strives to solve new challenges. These include drug targeting, biomolecular therapeutics, development of chemical biology tools, data collection and analysis, in silico models as predictors for biological properties, identification and validation of new targets, approaches to quantify target engagement, new methods for synthesis of drug candidates such as green chemistry, development of novel scaffolds for drug discovery, and the role of regulatory agencies in drug discovery. Reviews the strategies, technologies, principles, and applications of modern medicinal chemistry Provides a global and current perspective of today's drug discovery process and discusses the major therapeutic classes and targets Includes a unique collection of case studies and personal assays reviewing the discovery and development of key drugs

Comprehensive Medicinal Chemistry III

Author :
Publisher : Elsevier
ISBN 13 : 9780128032008
Total Pages : 0 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Comprehensive Medicinal Chemistry III by :

Download or read book Comprehensive Medicinal Chemistry III written by and published by Elsevier. This book was released on 2017-07-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Medicinal Chemistry III, Eight Volume Set provides a contemporary and forward-looking critical analysis and summary of recent developments, emerging trends, and recently identified new areas where medicinal chemistry is having an impact. The discipline of medicinal chemistry continues to evolve as it adapts to new opportunities and strives to solve new challenges. These include drug targeting, biomolecular therapeutics, development of chemical biology tools, data collection and analysis, in silico models as predictors for biological properties, identification and validation of new targets, approaches to quantify target engagement, new methods for synthesis of drug candidates such as green chemistry, development of novel scaffolds for drug discovery, and the role of regulatory agencies in drug discovery. Reviews the strategies, technologies, principles, and applications of modern medicinal chemistry Provides a global and current perspective of today's drug discovery process and discusses the major therapeutic classes and targets Includes a unique collection of case studies and personal assays reviewing the discovery and development of key drugs

Medicinal Chemistry - III

Author : K G Bothara
Publisher :
ISBN 13 : 9789386084460
Total Pages : 148 pages
Book Rating : 4.0/5 (844 download)

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Book Synopsis Medicinal Chemistry - III by : K G Bothara

Download or read book Medicinal Chemistry - III written by K G Bothara and published by . This book was released on 2016-07-16 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: 1 Narcotic analgesics 2 Anti inflammatory agents 3 Autacoids 4 Drugs acting on respiratory tract 5 Drugs acting on gastrointestinal tract Index

Comprehensive Medicinal Chemistry III

Author : Samuel Chackalamannil
Publisher :
ISBN 13 : 9780081022405
Total Pages : 610 pages
Book Rating : 4.0/5 (224 download)

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Book Synopsis Comprehensive Medicinal Chemistry III by : Samuel Chackalamannil

Download or read book Comprehensive Medicinal Chemistry III written by Samuel Chackalamannil and published by . This book was released on 2017 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Medicinal Chemistry—III

Author : P. Pratesi
Publisher : Elsevier
ISBN 13 : 1483284743
Total Pages : 177 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Medicinal Chemistry—III by : P. Pratesi

Download or read book Medicinal Chemistry—III written by P. Pratesi and published by Elsevier. This book was released on 2013-10-22 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal Chemistry–III provides information pertinent to the fundamental aspects of medicinal chemistry. This book discusses the mechanism of action of drugs at the molecular level. Organized into eight chapters, this book begins with an overview of the systems for protein biosynthesis that are classified according to their mechanism and the selective action of drugs on their reactions. This text then examines the key structure in the biosynthesis of the peptidoglycans of bacterial cell walls. Other chapters consider the enzymes that transcribe DNA synthesizing RNA, which have structural differences in eukaryotic and prokaryotic cells. This book discusses as well the concepts for drug screening as they have been emerged from neurochemical research. The final chapter deals with the significance of molecular orbital theory in the hands of the biologist or chemists, which lies in its ability to derive information regarding the properties of molecules. This book is a valuable resource for organic, physical, and biological chemists.

Pharmaceutical Chemistry III

Author :
Publisher : Krishna Prakashan Media
ISBN 13 : 9788182830585
Total Pages : 256 pages
Book Rating : 4.8/5 (35 download)

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Book Synopsis Pharmaceutical Chemistry III by :

Download or read book Pharmaceutical Chemistry III written by and published by Krishna Prakashan Media. This book was released on with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Medicinal Chemistry

Author : Thomas Nogrady
Publisher : Oxford University Press
ISBN 13 : 0190282967
Total Pages : 664 pages
Book Rating : 4.1/5 (92 download)

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Book Synopsis Medicinal Chemistry by : Thomas Nogrady

Download or read book Medicinal Chemistry written by Thomas Nogrady and published by Oxford University Press. This book was released on 2005-08-11 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fully updated and rewritten by a basic scientist who is also a practicing physician, the third edition of this popular textbook remains comprehensive, authoritative and readable. Taking a receptor-based, target-centered approach, it presents the concepts central to the study of drug action in a logical, mechanistic way grounded on molecular and principles. Students of pharmacy, chemistry and pharmacology, as well as researchers interested in a better understanding of drug design, will find this book an invaluable resource. Starting with an overview of basic principles, Medicinal Chemistry examines the properties of drug molecules, the characteristics of drug receptors, and the nature of drug-receptor interactions. Then it systematically examines the various families of receptors involved in human disease and drug design. The first three classes of receptors are related to endogenous molecules: neurotransmitters, hormones and immunomodulators. Next, receptors associated with cellular organelles (mitochondria, cell nucleus), endogenous macromolecules (membrane proteins, cytoplasmic enzymes) and pathogens (viruses, bacteria) are examined. Through this evaluation of receptors, all the main types of human disease and all major categories of drugs are considered. There have been many changes in the third edition, including a new chapter on the immune system. Because of their increasingly prominent role in drug discovery, molecular modeling techniques, high throughput screening, neuropharmacology and genetics/genomics are given much more attention. The chapter on hormonal therapies has been thoroughly updated and re-organized. Emerging enzyme targets in drug design (e.g. kinases, caspases) are discussed, and recent information on voltage-gated and ligand-gated ion channels has been incorporated. The sections on antihypertensive, antiviral, antibacterial, anti-inflammatory, antiarrhythmic, and anticancer drugs, as well as treatments for hyperlipidemia and peptic ulcer, have been substantially expanded. One new feature will enhance the book's appeal to all readers: clinical-molecular interface sections that facilitate understanding of the treatment of human disease at a molecular level.

The Practice of Medicinal Chemistry

Author : Camille Georges Wermuth
Publisher : Elsevier
ISBN 13 : 012417213X
Total Pages : 903 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis The Practice of Medicinal Chemistry by : Camille Georges Wermuth

Download or read book The Practice of Medicinal Chemistry written by Camille Georges Wermuth and published by Elsevier. This book was released on 2015-07-01 with total page 903 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Practice of Medicinal Chemistry, Fourth Edition provides a practical and comprehensive overview of the daily issues facing pharmaceutical researchers and chemists. In addition to its thorough treatment of basic medicinal chemistry principles, this updated edition has been revised to provide new and expanded coverage of the latest technologies and approaches in drug discovery. With topics like high content screening, scoring, docking, binding free energy calculations, polypharmacology, QSAR, chemical collections and databases, and much more, this book is the go-to reference for all academic and pharmaceutical researchers who need a complete understanding of medicinal chemistry and its application to drug discovery and development. Includes updated and expanded material on systems biology, chemogenomics, computer-aided drug design, and other important recent advances in the field Incorporates extensive color figures, case studies, and practical examples to help users gain a further understanding of key concepts Provides high-quality content in a comprehensive manner, including contributions from international chapter authors to illustrate the global nature of medicinal chemistry and drug development research An image bank is available for instructors at www.textbooks.elsevier.com

MEDICINAL CHEMISTRY - III

Author : SunilaT. Patil
Publisher :
ISBN 13 : 9789389686753
Total Pages : 58 pages
Book Rating : 4.6/5 (867 download)

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Book Synopsis MEDICINAL CHEMISTRY - III by : SunilaT. Patil

Download or read book MEDICINAL CHEMISTRY - III written by SunilaT. Patil and published by . This book was released on 2020 with total page 58 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Medicinal chemistry - III: main lectures, ed

Author : International Symposium on Medicinal Chemistry, 3rd, Milan, 1972
Publisher :
ISBN 13 : 9780408705387
Total Pages : 170 pages
Book Rating : 4.7/5 (53 download)

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Book Synopsis Medicinal chemistry - III: main lectures, ed by : International Symposium on Medicinal Chemistry, 3rd, Milan, 1972

Download or read book Medicinal chemistry - III: main lectures, ed written by International Symposium on Medicinal Chemistry, 3rd, Milan, 1972 and published by . This book was released on with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt:

MEDICINAL CHEMISTRY - III

Author : SanjayG. Walode
Publisher :
ISBN 13 : 9789389944068
Total Pages : 260 pages
Book Rating : 4.9/5 (44 download)

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Book Synopsis MEDICINAL CHEMISTRY - III by : SanjayG. Walode

Download or read book MEDICINAL CHEMISTRY - III written by SanjayG. Walode and published by . This book was released on 2020-02 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt:

MEDICINAL CHEMISTRY - III

Author : SunilaT. Patil
Publisher :
ISBN 13 : 9789389686753
Total Pages : 58 pages
Book Rating : 4.6/5 (867 download)

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Book Synopsis MEDICINAL CHEMISTRY - III by : SunilaT. Patil

Download or read book MEDICINAL CHEMISTRY - III written by SunilaT. Patil and published by . This book was released on 2020 with total page 58 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Platform Technologies in Drug Discovery and Validation

Author :
Publisher : Academic Press
ISBN 13 : 0128130709
Total Pages : 690 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Platform Technologies in Drug Discovery and Validation by :

Download or read book Platform Technologies in Drug Discovery and Validation written by and published by Academic Press. This book was released on 2017-11-21 with total page 690 pages. Available in PDF, EPUB and Kindle. Book excerpt: Platform Technologies in Drug Discovery and Validation, Volume 50, the latest release in the Annual Reports in Medicinal Chemistry series, provides timely and critical reviews of important topics in medicinal chemistry, with an emphasis on emerging topics in the biological sciences. Topics covered in this new volume include DELT, Oligos: ASO, siRNA, CRISPR, Micro-fluidic chemistry, High throughput screening, Kinase-centric computational drug development, Virtual Screening, Phenotypic screening, PROTACS, Chemical Biology, Fragment-based lead generation, Antibody-Drug Conjugates, Antibody-recruiting small molecules, Deuteration, and Peptides. Unique for its treatment of platform technologies for medicinal chemistry and target validation Provides a single, rich volume that summaries a broad spectrum of expertise relevant to the field Presents state-of-the-art summaries of platform technologies

Basic Concepts in Medicinal Chemistry

Author : Marc Harrold
Publisher : ASHP
ISBN 13 : 1585283649
Total Pages : 405 pages
Book Rating : 4.5/5 (852 download)

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Book Synopsis Basic Concepts in Medicinal Chemistry by : Marc Harrold

Download or read book Basic Concepts in Medicinal Chemistry written by Marc Harrold and published by ASHP. This book was released on 2013-01-18 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal chemistry is a complex topic. Written in an easy to follow and conversational style, Basic Concepts in Medicinal Chemistry focuses on the fundamental concepts that govern the discipline of medicinal chemistry as well as how and why these concepts are essential to therapeutic decisions. The book emphasizes functional group analysis and the basics of drug structure evaluation. In a systematic fashion, learn how to identify and evaluate the functional groups that comprise the structure of a drug molecule and their influences on solubility, absorption, acid/base character, binding interactions, and stereochemical orientation. Relevant Phase I and Phase II metabolic transformations are also discussed for each functional group. Key features include: • Discussions on the roles and characteristics of organic functional groups, including the identification of acidic and basic functional groups. • How to solve problems involving pH, pKa, and ionization; salts and solubility; drug binding interactions; stereochemistry; and drug metabolism. • Numerous examples and expanded discussions for complex concepts. • Therapeutic examples that link the importance of medicinal chemistry to pharmacy and healthcare practice. • An overview of structure activity relationships (SARs) and concepts that govern drug design. • Review questions and practice problems at the end of each chapter that allow readers to test their understanding, with the answers provided in an appendix. Whether you are just starting your education toward a career in a healthcare field or need to brush up on your organic chemistry concepts, this book is here to help you navigate medicinal chemistry. About the Authors Marc W. Harrold, BS, Pharm, PhD, is Professor of Medicinal Chemistry at the Mylan School of Pharmacy, Duquesne University, Pittsburgh, PA. Professor Harrold is the 2011 winner of the Omicron Delta Kappa "Teacher of the Year" award at Duquesne University. He is also the two-time winner of the "TOPS" (Teacher of the Pharmacy School) award at the Mylan School of Pharmacy. Robin M. Zavod, PhD, is Associate Professor for Pharmaceutical Sciences at the Chicago College of Pharmacy, Midwestern University, Downers Grove, IL, where she was awarded the 2012 Outstanding Faculty of the Year award. Professor Zavod also serves on the adjunct faculty for Elmhurst College and the Illinois Institute of Technology. She currently serves as Editor-in-Chief of the journal Currents in Pharmacy Teaching and Learning.

Advances in Medicinal Chemistry

Author : B.E. Maryanoff
Publisher : Elsevier
ISBN 13 : 0080526373
Total Pages : 338 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Advances in Medicinal Chemistry by : B.E. Maryanoff

Download or read book Advances in Medicinal Chemistry written by B.E. Maryanoff and published by Elsevier. This book was released on 1999-04-01 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 4 of Advances in Medicinal Chemistry is comprised of six chapters on a wide range of topics in medicinal chemistry, including molecular modeling, structure-based drug design, organic synthesis, peptide conformational analysis, biological assessment, structure-activity correlation, and lead optimization. Chapter 1 presents an account about amino acid-based peptide mimetics corresponding to b-turn, loop, helical motifs in proteins as a probe of ligand-receptor and ligand-enzyme molecular interactions. Chapter 2 addresses new facets of the medicinal chemistry of the important anticancer drug Taxol® (paclitaxel). Chapter 3 relates an account of the search for new drugs for the treatment of malaria based on the natural product artemisinin. Chapter 4 applies computational chemistry to the evaluation of compound libraries for biological testing. Chapter 5 describes the construction of a 3-dimensional molecular model of the human thrombin receptor, the first protease-activated G-protein coupled receptor (PAR-1), as a means to explore the intermolecular contacts involved in agonist peptide recognition. Finally, Chapter 6 describes the research conducted at Merck on inhibitors of farnesyl transferase as a potential treatment for human cancers.

Textbook of Medicinal Chemistry Vol II - E-Book

Author : V Alagarsamy
Publisher : Elsevier Health Sciences
ISBN 13 : 813123259X
Total Pages : 833 pages
Book Rating : 4.1/5 (312 download)

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Book Synopsis Textbook of Medicinal Chemistry Vol II - E-Book by : V Alagarsamy

Download or read book Textbook of Medicinal Chemistry Vol II - E-Book written by V Alagarsamy and published by Elsevier Health Sciences. This book was released on 2012-06-16 with total page 833 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr Alagarsamy's Textbook of Medicinal Chemistry is a much-awaited masterpiece in its arena. Targeted mainly to B. Pharm. students, this book will also be useful for M. Pharm. as well as M. Sc. organic chemistry and pharmaceutical chemistry students. It aims at eliminating the inadequacies in teaching and learning of medicinal chemistry by providing enormous information on all the topics in medicinal chemistry of synthetic drugs. Salient Features Contains clear classification, synthetic schemes, mode of action, metabolism, assay, pharmacological uses with the dose and structure–activity relationship (SAR) of the following classes of drugs: Drugs acting on inflammation Drugs acting on respiratory system Drugs acting on digestive system Drugs acting on blood and blood-forming organs Drugs acting on endocrine system Contains a complete section on chemotherapy and the various classes of chemotherapeutic agents. Also includes recent topics like anti-HIV agents Contains brief introduction about the physiological and pathophysiological conditions of diseases and their treatment under each topic Provides well-illustrated synthetic schemes and alternative synthetic routes for majority of drugs that help in quick and enhanced understanding of the subject Covers the syllabi of majority of Indian universities

A Textbook of Medicinal Chemistry III

Author : A Rajendiran, Ajay Kumar Gupta and Anju Singh
Publisher : Shashwat Publication
ISBN 13 : 8119517997
Total Pages : 186 pages
Book Rating : 4.1/5 (195 download)

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Book Synopsis A Textbook of Medicinal Chemistry III by : A Rajendiran, Ajay Kumar Gupta and Anju Singh

Download or read book A Textbook of Medicinal Chemistry III written by A Rajendiran, Ajay Kumar Gupta and Anju Singh and published by Shashwat Publication. This book was released on 2023-11-03 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook of Medicinal Chemistry is useful for all the disciplines, course and programs related to medicinal chemistry that involves the integration of principles of medicinal chemistry with pharmacology, pharmaceutics, and therapeutics into a multi-semester course called pharmacodynamics, pharmacotherapeutics, or another similar name. But this book is more precise for students of pharmaceutical sciences, with special emphasis on syllabus prescribed by Pharmacy Council of India (PCI) for undergraduate students of all Indian Universities. The chapters of this textbook include a combination of principles of pharmacology and medicinal chemistry, necessary for understanding structure–activity relationships (SAR) and mechanisms of drug action (MOA), the book should be useful in supporting courses in medicinal chemistry and in complementing pharmacology courses. The authors of this textbook of Medicinal Chemistry III are pharmacy professionals, and are influenced by respective academic backgrounds, with the objective of continuing the tradition of a modern textbook for undergraduate students and also for graduate students who need a general review of medicinal chemistry. We believe that our collaboration on this textbook represents a blending of our perspectives that will provide new dimensions of appreciation and better understanding for students of pharmaceutical sciences. Finally in writing this multi-authored textbook we have tried to simplify with consistent style in the respective chapters.