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Medical Statistics For Cancer Studies
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Book Synopsis Medical Statistics for Cancer Studies by : Trevor F. Cox
Download or read book Medical Statistics for Cancer Studies written by Trevor F. Cox and published by CRC Press. This book was released on 2022-06-23 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer is a dreaded disease. One in two people will be diagnosed with cancer within their lifetime. Medical Statistics for Cancer Studies shows how cancer data can be analysed in a variety of ways, covering cancer clinical trial data, epidemiological data, biological data, and genetic data. It gives some background in cancer biology and genetics, followed by detailed overviews of survival analysis, clinical trials, regression analysis, epidemiology, meta-analysis, biomarkers, and cancer informatics. It includes lots of examples using real data from the author’s many years of experience working in a cancer clinical trials unit. Features: A broad and accessible overview of statistical methods in cancer research Necessary background in cancer biology and genetics Details of statistical methodology with minimal algebra Many examples using real data from cancer clinical trials Appendix giving statistics revision.
Download or read book Advanced Medical Statistics written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Statistical Methods for Cancer Studies by : Richard G. Cornell
Download or read book Statistical Methods for Cancer Studies written by Richard G. Cornell and published by CRC Press. This book was released on 2020-11-26 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on public health and epidemiologic aspects of cancer, and explores the sources of information concerning the frequency of occurrence of human cancer. It describes statistical methods useful in studying problems arising in the field of cancer and its concurrent development.
Book Synopsis Medical Uses of Statistics by : John C. Bailar III
Download or read book Medical Uses of Statistics written by John C. Bailar III and published by CRC Press. This book was released on 2019-05-20 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work explains the purpose of statistical methods in medical studies and analyzes the statistical techniques used by clinical investigators, with special emphasis on studies published in "The New England Journal of Medicine". It clarifies fundamental concepts of statistical design and analysis, and facilitates the understanding of research results.
Book Synopsis Handbook of Statistics in Clinical Oncology, Third Edition by : John Crowley
Download or read book Handbook of Statistics in Clinical Oncology, Third Edition written by John Crowley and published by CRC Press. This book was released on 2012-03-26 with total page 661 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many new challenges have arisen in the area of oncology clinical trials. New cancer therapies are often based on cytostatic or targeted agents, which pose new challenges in the design and analysis of all phases of trials. The literature on adaptive trial designs and early stopping has been exploding. Inclusion of high-dimensional data and imaging techniques have become common practice, and statistical methods on how to analyse such data have been refined in this area. A compilation of statistical topics relevant to these new advances in cancer research, this third edition of Handbook of Statistics in Clinical Oncology focuses on the design and analysis of oncology clinical trials and translational research. Addressing the many challenges that have arisen since the publication of its predecessor, this third edition covers the newest developments involved in the design and analysis of cancer clinical trials, incorporating updates to all four parts: Phase I trials: Updated recommendations regarding the standard 3 + 3 and continual reassessment approaches, along with new chapters on phase 0 trials and phase I trial design for targeted agents. Phase II trials: Updates to current experience in single-arm and randomized phase II trial designs. New chapters include phase II designs with multiple strata and phase II/III designs. Phase III trials: Many new chapters include interim analyses and early stopping considerations, phase III trial designs for targeted agents and for testing the ability of markers, adaptive trial designs, cure rate survival models, statistical methods of imaging, as well as a thorough review of software for the design and analysis of clinical trials. Exploratory and high-dimensional data analyses: All chapters in this part have been thoroughly updated since the last edition. New chapters address methods for analyzing SNP data and for developing a score based on gene expression data. In addition, chapters on risk calculators and forensic bioinformatics have been added. Accessible to statisticians and oncologists interested in clinical trial methodology, the book is a single-source collection of up-to-date statistical approaches to research in clinical oncology.
Book Synopsis Analysis of Cancer Risks in Populations Near Nuclear Facilities by : National Research Council
Download or read book Analysis of Cancer Risks in Populations Near Nuclear Facilities written by National Research Council and published by National Academies Press. This book was released on 2012-06-29 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the late 1980s, the National Cancer Institute initiated an investigation of cancer risks in populations near 52 commercial nuclear power plants and 10 Department of Energy nuclear facilities (including research and nuclear weapons production facilities and one reprocessing plant) in the United States. The results of the NCI investigation were used a primary resource for communicating with the public about the cancer risks near the nuclear facilities. However, this study is now over 20 years old. The U.S. Nuclear Regulatory Commission requested that the National Academy of Sciences provide an updated assessment of cancer risks in populations near USNRC-licensed nuclear facilities that utilize or process uranium for the production of electricity. Analysis of Cancer Risks in Populations near Nuclear Facilities: Phase 1 focuses on identifying scientifically sound approaches for carrying out an assessment of cancer risks associated with living near a nuclear facility, judgments about the strengths and weaknesses of various statistical power, ability to assess potential confounding factors, possible biases, and required effort. The results from this Phase 1 study will be used to inform the design of cancer risk assessment, which will be carried out in Phase 2. This report is beneficial for the general public, communities near nuclear facilities, stakeholders, healthcare providers, policy makers, state and local officials, community leaders, and the media.
Book Synopsis Medical Statistics at a Glance by : Aviva Petrie
Download or read book Medical Statistics at a Glance written by Aviva Petrie and published by John Wiley & Sons. This book was released on 2013-11-08 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical Statistics at a Glance is a concise and accessible introduction and revision aid for this complex subject. The self-contained chapters explain the underlying concepts of medical statistics and provide a guide to the most commonly used statistical procedures. This new edition of Medical Statistics at a Glance: Presents key facts accompanied by clear and informative tables and diagrams Focuses on illustrative examples which show statistics in action, with an emphasis on the interpretation of computer data analysis rather than complex hand calculations Includes extensive cross-referencing, a comprehensive glossary of terms and flow-charts to make it easier to choose appropriate tests Now provides the learning objectives for each chapter Includes a new chapter on Developing Prognostic Scores Includes new or expanded material on study management, multi-centre studies, sequential trials, bias and different methods to remove confounding in observational studies, multiple comparisons, ROC curves and checking assumptions in a logistic regression analysis The companion website at www.medstatsaag.com contains supplementary material including an extensive reference list and multiple choice questions (MCQs) with interactive answers for self-assessment. Medical Statistics at a Glance will appeal to all medical students, junior doctors and researchers in biomedical and pharmaceutical disciplines. Reviews of the previous editions "The more familiar I have become with this book, the more I appreciate the clear presentation and unthreatening prose. It is now a valuable companion to my formal statistics course." –International Journal of Epidemiology "I heartily recommend it, especially to first years, but it's equally appropriate for an intercalated BSc or Postgraduate research. If statistics give you headaches - buy it. If statistics are all you think about - buy it." –GKT Gazette "...I unreservedly recommend this book to all medical students, especially those that dislike reading reams of text. This is one book that will not sit on your shelf collecting dust once you have graduated and will also function as a reference book." –4th Year Medical Student, Barts and the London Chronicle, Spring 2003
Book Synopsis Biostatistical Applications in Cancer Research by : Craig Beam
Download or read book Biostatistical Applications in Cancer Research written by Craig Beam and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biostatistics is defined as much by its application as it is by theory. This book provides an introduction to biostatistical applications in modern cancer research that is both accessible and valuable to the cancer biostatistician or to the cancer researcher, learning biostatistics. The topical areas include active areas of the application of biostatistics to modern cancer research: survival analysis, screening, diagnostics, spatial analysis and the analysis of microarray data. Biostatistics is an essential component of basic and clinical cancer research. The text, authored by distinguished figures in the field, addresses clinical issues in statistical analysis. The spectrum of topics discussed ranges from fundamental methodology to clinical and translational applications.
Book Synopsis Transforming Clinical Research in the United States by : Institute of Medicine
Download or read book Transforming Clinical Research in the United States written by Institute of Medicine and published by National Academies Press. This book was released on 2010-10-22 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt: An ideal health care system relies on efficiently generating timely, accurate evidence to deliver on its promise of diminishing the divide between clinical practice and research. There are growing indications, however, that the current health care system and the clinical research that guides medical decisions in the United States falls far short of this vision. The process of generating medical evidence through clinical trials in the United States is expensive and lengthy, includes a number of regulatory hurdles, and is based on a limited infrastructure. The link between clinical research and medical progress is also frequently misunderstood or unsupported by both patients and providers. The focus of clinical research changes as diseases emerge and new treatments create cures for old conditions. As diseases evolve, the ultimate goal remains to speed new and improved medical treatments to patients throughout the world. To keep pace with rapidly changing health care demands, clinical research resources need to be organized and on hand to address the numerous health care questions that continually emerge. Improving the overall capacity of the clinical research enterprise will depend on ensuring that there is an adequate infrastructure in place to support the investigators who conduct research, the patients with real diseases who volunteer to participate in experimental research, and the institutions that organize and carry out the trials. To address these issues and better understand the current state of clinical research in the United States, the Institute of Medicine's (IOM) Forum on Drug Discovery, Development, and Translation held a 2-day workshop entitled Transforming Clinical Research in the United States. The workshop, summarized in this volume, laid the foundation for a broader initiative of the Forum addressing different aspects of clinical research. Future Forum plans include further examining regulatory, administrative, and structural barriers to the effective conduct of clinical research; developing a vision for a stable, continuously funded clinical research infrastructure in the United States; and considering strategies and collaborative activities to facilitate more robust public engagement in the clinical research enterprise.
Book Synopsis Medical Statistics by : Michael J. Campbell
Download or read book Medical Statistics written by Michael J. Campbell and published by John Wiley & Sons. This book was released on 2010-10-26 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides students and practitioners with a clear, conciseintroduction to the statistics they will come across in theirregular reading of clinical papers. Written by three experts with wide teaching and consultingexperience, Medical Statistics: A Textbook for the HealthSciences, Fourth Edition: Assumes no prior knowledge of statistics Covers all essential statistical methods Completely revised, updated and expanded Includes numerous examples and exercises on the interpretationof the statistics in papers published in medical journals From the reviews of the previous edition: "The book has several excellent features: it is written bystatisticians, is.... well presented, is well referenced.... and isshort." THE LANCET "Many statisticians are concerned at the generally poorstandard of statistics in papers published in medical journals.Perhaps this could be remedied if more research workers would sparea few hours to read through Campbell and Machin's book."BRITISH MEDICAL JOURNAL "... a simple, interesting and insightful introduction tomedical statistics... highlyrecommended." STATISTICAL METHODS IN MEDICALRESEARCH "Campbell and Machin found the golden mean... this book canbe recommended for all students and all medicalresearchers." ISCB NEWSLETTER
Book Synopsis Handbook of Statistics in Clinical Oncology by : John Crowley
Download or read book Handbook of Statistics in Clinical Oncology written by John Crowley and published by CRC Press. This book was released on 2005-12-01 with total page 642 pages. Available in PDF, EPUB and Kindle. Book excerpt: A compendium of cutting-edge statistical approaches to solving problems in clinical oncology, Handbook of Statistics in Clinical Oncology, Second Edition focuses on clinical trials in phases I, II, and III, proteomic and genomic studies, complementary outcomes and exploratory methods. Cancer Forum called the first edition a
Book Synopsis Practical Statistics for Medical Research by : Douglas G. Altman
Download or read book Practical Statistics for Medical Research written by Douglas G. Altman and published by CRC Press. This book was released on 1990-11-22 with total page 630 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most medical researchers, whether clinical or non-clinical, receive some background in statistics as undergraduates. However, it is most often brief, a long time ago, and largely forgotten by the time it is needed. Furthermore, many introductory texts fall short of adequately explaining the underlying concepts of statistics, and often are divorced from the reality of conducting and assessing medical research. Practical Statistics for Medical Research is a problem-based text for medical researchers, medical students, and others in the medical arena who need to use statistics but have no specialized mathematics background. The author draws on twenty years of experience as a consulting medical statistician to provide clear explanations to key statistical concepts, with a firm emphasis on practical aspects of designing and analyzing medical research. The text gives special attention to the presentation and interpretation of results and the many real problems that arise in medical research.
Download or read book The Cancer Atlas written by Ahmedin Jemal and published by . This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This atlas illustrates the latest available data on the cancer epidemic, showing causes, stages of development, and prevalence rates of different types of cancers by gender, income group, and region. It also examines the cost of the disease, both in terms of health care and commercial interests, and the steps being taken to curb the epidemic, from research and screening to cancer management programs and health education.
Book Synopsis Medical Statistics at a Glance by : Aviva Petrie
Download or read book Medical Statistics at a Glance written by Aviva Petrie and published by Wiley-Blackwell. This book was released on 2000-08-16 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: In line with the other books in the at a Glance series, Medical Statistics at a Glance leads the reader through a number of self-contained topics, each covering a different aspect of medical statistics. The majority of these use the standard 'At a Glance' format of two pages per topic. The authors have provided a basic introduction to the underlying concepts of medical statistics and a guide to the most commonly used statistical procedures. Topics describing a statistical technique are accompanied by a worked example, using real data, illustrating its use. Where possible, the same data set has been used in more than one topic to reflect the reality of data analysis. Detailed and complex hand calculations have been avoided with a concentration on the interpretation of computer data analysis. Medical Statistics at a Glance is versatile in its use as an explanation, a revision summary and a long-term source of reference. Worked examples to accompany each topic. Emphasis on computer analysis of data rather than hand calculations. Supported by a website at http://www.medstatsaag.com/ - this site contains useful self-assessment questions to aid student learning.
Book Synopsis Handbook of Statistics in Clinical Oncology by : John Crowley
Download or read book Handbook of Statistics in Clinical Oncology written by John Crowley and published by CRC Press. This book was released on 2001-04-27 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book compiles state-of-the-art statistical approaches to solving problems in clinical oncology, focusing on clinical trials in phases I, II, and III, as well as quality of life and economic analyses, and exploratory methods. Examines trial design treatment based on toxicity and survival! Featuring over 1000 references, more than 40 world-renowned contributors, and 300 equations, tables, and drawings, the Handbook of Statistics in Clinical Oncology provides a comprehensive discussion of sample size considers analytical problems generated by controlling treatment costs and maintaining quality of life demonstrates the breadth and depth of current activity in the field of survival analysis sets the limits on what can and cannot be concluded from single and multiple clinical trials and more! The best single source for up-to-date graphical, tree-based, and other statistical methods, the Handbook of Statistics in Clinical Oncology is fascinating reading for oncologists, cancer researchers, biostatisticians, applied statisticians, and medical and graduate students in these disciplines.
Book Synopsis Fast Facts: Medical Statistics by : Richard Kay
Download or read book Fast Facts: Medical Statistics written by Richard Kay and published by Karger Medical and Scientific Publishers. This book was released on 2020-07-17 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using real examples from oncology trials, but keeping it simple, this concise resource explains the basic principles of medical statistics so that you can better appraise clinical trial results. Key concepts covered in this book include: • hypothesis testing • Kaplan–Meier curves and other graphic representations of data • calculating the power of a study • the stopping rules for efficacy and futility. ' Fast Facts: Medical Statistics' is aimed at all clinicians, clinical scientists, medical writers and regulatory personnel who need a better understanding of the statistical terms and methods used in the planning of studies and the analysis of clinical trial data. If you have ever wanted to know what a type I error is, how an odds ratio is calculated or what a forest plot is really all about, then this is the book for you. Contents: • Statistical inference • Analysis of time-to-event endpoints • Power and sample size • Multiplicity • Interim analysis • Modeling • Graphical methods
Book Synopsis Medical Statistics by : Stephen J. Walters
Download or read book Medical Statistics written by Stephen J. Walters and published by John Wiley & Sons. This book was released on 2021-02-01 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 5th edition of this popular introduction to statistics for the medical and health sciences has undergone a significant revision, with several new chapters added and examples refreshed throughout the book. Yet it retains its central philosophy to explain medical statistics with as little technical detail as possible, making it accessible to a wide audience. Helpful multi-choice exercises are included at the end of each chapter, with answers provided at the end of the book. Each analysis technique is carefully explained and the mathematics kept to minimum. Written in a style suitable for statisticians and clinicians alike, this edition features many real and original examples, taken from the authors' combined many years' experience of designing and analysing clinical trials and teaching statistics. Students of the health sciences, such as medicine, nursing, dentistry, physiotherapy, occupational therapy, and radiography should find the book useful, with examples relevant to their disciplines. The aim of training courses in medical statistics pertinent to these areas is not to turn the students into medical statisticians but rather to help them interpret the published scientific literature and appreciate how to design studies and analyse data arising from their own projects. However, the reader who is about to design their own study and collect, analyse and report on their own data will benefit from a clearly written book on the subject which provides practical guidance to such issues. The practical guidance provided by this book will be of use to professionals working in and/or managing clinical trials, in academic, public health, government and industry settings, particularly medical statisticians, clinicians, trial co-ordinators. Its practical approach will appeal to applied statisticians and biomedical researchers, in particular those in the biopharmaceutical industry, medical and public health organisations.