Mechanisms of Intracellular Trafficking and Processing of Proproteins

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Publisher : CRC Press
ISBN 13 : 9780849368707
Total Pages : 312 pages
Book Rating : 4.3/5 (687 download)

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Book Synopsis Mechanisms of Intracellular Trafficking and Processing of Proproteins by : Y. Peng Loh

Download or read book Mechanisms of Intracellular Trafficking and Processing of Proproteins written by Y. Peng Loh and published by CRC Press. This book was released on 1992-10-23 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mechanisms of Intracellular Trafficking and Processing of ProProteins provides an in-depth discussion of the cellular organization and current views of the molecular mechanisms underlying the trafficking, sorting, and processing of various classes of proproteins. The book covers the mechanisms of pro-protein translocation across the rough endoplasmic reticulum (RER) membrane and subsequent transport to the Golgi apparatus, molecular sorting and retention signals involved in directing pro-proteins to various cellular compartments, and the specific enzymes mediating different posttranslational modification steps. It is the only book that covers the principles of intracellular trafficking and processing of proproteins using examples representative of different classes of proproteins in the cell. New classes of enzymes, especially proteases with unique specificities, are examined as well. Mechanisms of Intracellular Trafficking and Processing of ProProteins presents a wealth of information valuable to cell biologists, endocrinologists, neurobiologists, enzymologists, and biochemists. Students studying molecular endocrinology, neurobiology, and cell biology will also find the book to be a useful text.

Aspartic Proteinases

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Publisher : Springer Science & Business Media
ISBN 13 : 1461518717
Total Pages : 614 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Aspartic Proteinases by : Kenji Takahashi

Download or read book Aspartic Proteinases written by Kenji Takahashi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 614 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 5th International Conference on Aspartic Proteinases was held on September 19 through 24, 1993, at Naito Museum of Pharmaceutical Science and Industry, Kawashima cho, Gifu Prefecture, Japan, about 15 miles northwest of Nagoya City. About 100 scientists attended the conference, including 52 from 14 countries outside Japan, and 32 papers were presented by invited speakers, and 58 papers as posters. The purpose of this conference was to present and discuss new information on the structure, function, and biology, and related topics, including biomedical implications, of aspartic proteinases, and this book is a collec tion of nearly all the papers presented at the meeting. Aspartic proteinases belong to one of the four major classes of proteinases, the others being serine, cysteine, and metalloproteinases, and are so called since they have two catalytic aspartic acid residues in common in their active sites. Most of them are optimally active at acidic pH, hence the long-used name "acid proteinases," which, indeed, was the major title of the first conference of this series. However, some of them are active at around neutral pH, indicating their physiological roles in a wider range of pH than hitherto considered.

Exploring Genetic Mechanisms

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Publisher : University Science Books
ISBN 13 : 9780935702705
Total Pages : 702 pages
Book Rating : 4.7/5 (27 download)

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Book Synopsis Exploring Genetic Mechanisms by : Maxine Singer

Download or read book Exploring Genetic Mechanisms written by Maxine Singer and published by University Science Books. This book was released on 1997-05-07 with total page 702 pages. Available in PDF, EPUB and Kindle. Book excerpt: An outstanding group of scientists have collaborated in the collection of case studies that comprise this major text-reference book. It examines in detail how genes operate in diverse living systems, including viruses, cells and more complex organisms; investigates how genotypes can be altered; and looks at the mapping and sequencing of human and other genomes. Students and professionals in biochemistry, molecular biology and genetics will enjoy this book.

Neurosecretion: Secretory Mechanisms

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Publisher : Springer Nature
ISBN 13 : 3030229890
Total Pages : 318 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Neurosecretion: Secretory Mechanisms by : José R. Lemos

Download or read book Neurosecretion: Secretory Mechanisms written by José R. Lemos and published by Springer Nature. This book was released on 2020-03-31 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: How do electrical activity and calcium signals in neurons influence the secretion of peptide hormones? This volume presents the current state of knowledge regarding the electrical, calcium signaling and synaptic properties of neuroendocrine systems from both vertebrate and invertebrate systems. The contributions span in vivo and in vitro studies that address: state‐dependent plasticity, relevance of firing patterns, membrane properties, calcium flux (including dynamic imaging and homeostasis), and molecular mechanisms of exocytosis, including from non-neuronal secretory cells. The chapters focus not only on research results but also on how experiments are conducted using state-of-the-art techniques, and how the resulting data are interpreted. While there are many books on the secretory properties of neurons, this is the first to focus on the distinctive secretory properties of neuroendocrine neurons. Accordingly, it offers an important text for undergraduate and graduate neuroscience students, and will also appeal to established scientists and postdoctoral fellows. This is the eighth volume in the Masterclass in Neuroendocrinology series* - now a co-publication between Springer Nature and the INF (International Neuroendocrine Federation). *Volumes 1-7 published by Wiley

Textbook of Energy Balance, Neuropeptide Hormones, and Neuroendocrine Function

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Author :
Publisher : Springer
ISBN 13 : 3319895060
Total Pages : 379 pages
Book Rating : 4.3/5 (198 download)

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Book Synopsis Textbook of Energy Balance, Neuropeptide Hormones, and Neuroendocrine Function by : Eduardo A. Nillni

Download or read book Textbook of Energy Balance, Neuropeptide Hormones, and Neuroendocrine Function written by Eduardo A. Nillni and published by Springer. This book was released on 2018-07-20 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook presents for the first time a comprehensive body of the latest knowledge in the field of neuropeptides and their action on energy balance. It contains a detailed and comprehensive account of the specific hypothalamic peptides in regards to their roles in energy balance, food intake control and co-morbidities, to better understand the patho-physiology of obesity. The textbook includes an examination the history of the evolution of human society from a thin to the obese phenotype and, within that context, how modern society habits and industrial food production did not respect the evolutionary trait resulting in changes in the energy balance set point. It provides a novel conceptualization of the problem of obesity when considering the biochemistry of peptide hormones and entertaining novel ideas on multiple approaches to the problems of energy balance, as well as demonstrates and explains why alterations in pro-hormone processing are paramount to understand metabolic disease. This text is excellent material for teaching graduate and medical school courses, as well as a valuable resource for researchers in biochemistry, cell, and molecular biology, neuroscientists, physician endocrinologists, and nutritionists.

The Peptidergic Neuron

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Publisher : Birkhäuser
ISBN 13 : 3034890109
Total Pages : 358 pages
Book Rating : 4.0/5 (348 download)

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Book Synopsis The Peptidergic Neuron by : B. Krisch

Download or read book The Peptidergic Neuron written by B. Krisch and published by Birkhäuser. This book was released on 2012-12-06 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuropeptides rank among the phylogenetically oldest interneuronal signal substances. In the concept of neuro-secretion they were identified as neurohormones by which - via the blood - the brain regulates peripheral functions. It is now evident that the neuropeptides act as neurotransmitters/-modulators, as (neuro-)hormones, and paracrine or autocrine signal substances in diverse parts of the body. This book reviews, in several comprehensive articles written by distinguished specialists, the state of the art in the field of neuropeptides and peptidergic neurons. Special topics concern molecular aspects of processing, release and degradation of neuropeptides, receptors and signal transduction, comparative and behavioural aspects, and immunoregulatory effects of neuropeptides and their involvement on pathology of the central nervous system.

Aspartic Proteinases Physiology and Pathology

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Publisher : CRC Press
ISBN 13 : 0429536003
Total Pages : 324 pages
Book Rating : 4.4/5 (295 download)

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Book Synopsis Aspartic Proteinases Physiology and Pathology by : Martin Fusek

Download or read book Aspartic Proteinases Physiology and Pathology written by Martin Fusek and published by CRC Press. This book was released on 2019-10-10 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Published in 1995: Aspartic Proteinases: Physiology and Pathology focuses on the advantages and limitations of the use of proteinases and their inhibitors in human pathology. A virus-specific aspartic proteinase enzyme is required for the maturation of a virus. If the enzyme can be eliminated, so can the maturation of the virus. This book reviews the wealth of recently published information sparked by the renewed interest in these enzymes.

Trafficking Inside Cells

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Publisher : Springer Science & Business Media
ISBN 13 : 038793877X
Total Pages : 459 pages
Book Rating : 4.3/5 (879 download)

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Book Synopsis Trafficking Inside Cells by : Nava Segev

Download or read book Trafficking Inside Cells written by Nava Segev and published by Springer Science & Business Media. This book was released on 2010-05-30 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the past, present and future of the intra-cellular trafficking field, which has made a quantum leap in the last few decades. It details how the field has developed and evolved as well as examines future directions.

National Library of Medicine Current Catalog

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Publisher :
ISBN 13 :
Total Pages : 1328 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis National Library of Medicine Current Catalog by : National Library of Medicine (U.S.)

Download or read book National Library of Medicine Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1993 with total page 1328 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Parathyroids

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Publisher : Elsevier
ISBN 13 : 0080525776
Total Pages : 921 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis The Parathyroids by : John P. Bilezikian

Download or read book The Parathyroids written by John P. Bilezikian and published by Elsevier. This book was released on 2001-07-21 with total page 921 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by world experts, this books follows upon the monumental success of the first edition of The Parathyroids, which was universally acclaimed as the best text on the subject. An authoritative reference that spans the basic science of parathyroid hormone treatment to major clinical disorders in a superb, single compendium, The Parathyroids offers an objective and authoritative view on controversial clinical issues in this rapidly changing field. Every medical school library and virtually every major hospital library will need this book as a reference for students and clinicians. Key Features * Offers objective and authoritative reviews on controversial clinical issues * Written by world experts on parathyroid hormone and its disorders * Superb, state-of-the-art compendium in one convenient volume * Bridges basic science of parathyroid hormone to major clinical disorders * Practical information on clinical management of parathyroid hormone disorders

ABC Transporters: Biochemical, Cellular, and Molecular Aspects

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Publisher : Gulf Professional Publishing
ISBN 13 : 9780121821937
Total Pages : 902 pages
Book Rating : 4.8/5 (219 download)

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Book Synopsis ABC Transporters: Biochemical, Cellular, and Molecular Aspects by : Suresh V. Ambudkar

Download or read book ABC Transporters: Biochemical, Cellular, and Molecular Aspects written by Suresh V. Ambudkar and published by Gulf Professional Publishing. This book was released on 1998-07-31 with total page 902 pages. Available in PDF, EPUB and Kindle. Book excerpt: The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. More than 285 volumes have been published (all of them still in print) and much of the material is relevant even today-truly an essential publication for researchersin all fields of life sciences. Prokaryotic ABC Transporters Eukaryotic ABC Transporters Nonmammalian ABC Transport Systems Mammalian P-Glycoproteins Multidrug Resistance Associated Protein Cystic Fibrosis Transmembrane Conductance Regulator Sulfonylurea Receptor Intracellular ABC Transporters

Glyco-and Cellbiology

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Publisher : Springer Science & Business Media
ISBN 13 : 3642787290
Total Pages : 194 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Glyco-and Cellbiology by : Felix Wieland

Download or read book Glyco-and Cellbiology written by Felix Wieland and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding the biological role of the diverse oligosaccharides of glycoproteins and glycolipids has been a major challenge in cell biology. Glycosylation is an essential step during molecular recognition and is involved in protein folding, sorting, targeting and intracellular translocation. Further, glycoproteins of the cell membrane play a major role in cell adhesion, hormone function, antibody action and signal mediation. Current knowledge of the molecular and cellular mechanisms involved in these processes is presented.

Current Catalog

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Author :
Publisher :
ISBN 13 :
Total Pages : 824 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Current Catalog by : National Library of Medicine (U.S.)

Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1993 with total page 824 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.

Handbook of Proteolytic Enzymes

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Publisher : Academic Press
ISBN 13 : 0123822203
Total Pages : 4097 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Handbook of Proteolytic Enzymes by : Alan J. Barrett

Download or read book Handbook of Proteolytic Enzymes written by Alan J. Barrett and published by Academic Press. This book was released on 2012-10-30 with total page 4097 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extensively revised and updated, the new edition of the highly regarded Handbook of Proteolytic Enzymes is an essential reference for biochemists, biotechnologists and molecular biologists. Edited by world-renowned experts in the field, this comprehensive work provides detailed information on all known proteolytic enzymes to date. This two-volume set unveils new developments on proteolytic enzymes which are being investigatedin pharmaceutical research for such diseases as HIV, Hepatitis C, and the common cold. Volume I covers aspartic and metallo petidases while Volume II examines peptidases of cysteine, serine, threonine and unknown catalytic type. A CD-ROM accompanies the book containing fully searchable text, specialised scissile bond searches, 3-D color structures and much more. The only comprehensive book on proteolytic enzymes Includes 671 chapters, each written by experts in their field, on proteolytic enzymes from all groups of living organisms and the viruses, including those that are currently major targets of pharmaceutical research Accompanying CD-ROM provides fully searchable text, 2D structures of peptidases in color and links directly to PubMed and MEROPS databases Each chapter describes in detail the enzyme name, its history, activity and specificity, structural chemistry, preparation, biological aspects and distinguishing features Over 1000 peptidases included

Principles and Practice of Endocrinology and Metabolism

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Publisher : Lippincott Williams & Wilkins
ISBN 13 : 9780781717502
Total Pages : 2500 pages
Book Rating : 4.7/5 (175 download)

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Book Synopsis Principles and Practice of Endocrinology and Metabolism by : Kenneth L. Becker

Download or read book Principles and Practice of Endocrinology and Metabolism written by Kenneth L. Becker and published by Lippincott Williams & Wilkins. This book was released on 2001 with total page 2500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Established as the foremost text in the field, Principles and Practice of Endocrinology and Metabolism is now in its thoroughly revised, updated Third Edition. This practical, clinically relevant, and comprehensive text covers the entire field of endocrinology and metabolism, including the diffuse endocrine system; morphology and physiology; diagnosis and treatment of endocrine diseases; endocrinology of the female; hormones and cancer; and much more. The Third Edition contains new chapters reflecting the latest advances and features expanded coverage of genetics and the endocrinology of sepsis. More than 1,400 illustrations complement the text. A drug formulary appears at the back of the book.

Neuropeptides

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Publisher : MIT Press
ISBN 13 : 9780262194075
Total Pages : 678 pages
Book Rating : 4.1/5 (94 download)

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Book Synopsis Neuropeptides by : Fleur L. Strand

Download or read book Neuropeptides written by Fleur L. Strand and published by MIT Press. This book was released on 1999 with total page 678 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook is the first to bring together and synthesize the neuropeptide research of the past decade in such a comprehensive, scholarly manner. In recent years there has been increasing interest and, subsequently, active research in neuropeptides. These neuroactive molecules coordinate, integrate, and regulate physiological processes in all organisms, throughout all phases of development. Acting as neurohormones, neurotransmitters, and/or neuromodulators, they maintain physiological homeostasis and influence important behavioral patterns. This textbook is the first to bring together and synthesize the neuropeptide research of the past decade in such a comprehensive, scholarly manner. The book is divided into two parts. In Part I the author defines the basic principles of neuropeptide action, including their biosynthesis, processing, transport, distribution, and interactions with receptors and second messenger systems. Strand also discusses the intimate interaction between the neuropeptides, stress, and the immune system. In Part II she discusses the regulatory functions of the families of neuropeptide in sufficient detail to provide both the advanced student and senior investigator with a thorough understanding of the most important neuropeptides. The text also contains a complete and up-to-date reference/reading list.

Journal of Cell Science

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Author :
Publisher :
ISBN 13 :
Total Pages : 796 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Journal of Cell Science by :

Download or read book Journal of Cell Science written by and published by . This book was released on 2004 with total page 796 pages. Available in PDF, EPUB and Kindle. Book excerpt: