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Author : Bruce Alberts
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Fumio Hanaoka
Publisher : Springer
ISBN 13 : 443155873X
Total Pages : 555 pages
Book Rating : 4.4/5 (315 download)
Download or read book DNA Replication, Recombination, and Repair written by Fumio Hanaoka and published by Springer. This book was released on 2016-01-22 with total page 555 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive review of the detailed molecular mechanisms of and functional crosstalk among the replication, recombination, and repair of DNA (collectively called the "3Rs") and the related processes, with special consciousness of their biological and clinical consequences. The 3Rs are fundamental molecular mechanisms for organisms to maintain and sometimes intentionally alter genetic information. DNA replication, recombination, and repair, individually, have been important subjects of molecular biology since its emergence, but we have recently become aware that the 3Rs are actually much more intimately related to one another than we used to realize. Furthermore, the 3R research fields have been growing even more interdisciplinary, with better understanding of molecular mechanisms underlying other important processes, such as chromosome structures and functions, cell cycle and checkpoints, transcriptional and epigenetic regulation, and so on. This book comprises 7 parts and 21 chapters: Part 1 (Chapters 1–3), DNA Replication; Part 2 (Chapters 4–6), DNA Recombination; Part 3 (Chapters 7–9), DNA Repair; Part 4 (Chapters 10–13), Genome Instability and Mutagenesis; Part 5 (Chapters 14–15), Chromosome Dynamics and Functions; Part 6 (Chapters 16–18), Cell Cycle and Checkpoints; Part 7 (Chapters 19–21), Interplay with Transcription and Epigenetic Regulation. This volume should attract the great interest of graduate students, postdoctoral fellows, and senior scientists in broad research fields of basic molecular biology, not only the core 3Rs, but also the various related fields (chromosome, cell cycle, transcription, epigenetics, and similar areas). Additionally, researchers in neurological sciences, developmental biology, immunology, evolutionary biology, and many other fields will find this book valuable.
Author : Nicholas R. Cozzarelli
Publisher :
ISBN 13 :
Total Pages : 912 pages
Book Rating : 4.:/5 (44 download)
Download or read book Mechanisms of DNA Replication and Recombination written by Nicholas R. Cozzarelli and published by . This book was released on 1983 with total page 912 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of a UCLA Symposium held in Keystone, Colorado, April, 3-9, 1983.
Author : Bruce Alberts
Publisher : Elsevier
ISBN 13 : 032314179X
Total Pages : 1034 pages
Book Rating : 4.3/5 (231 download)
Download or read book mechanistic studies of DNA replication and genetic recombination written by Bruce Alberts and published by Elsevier. This book was released on 2012-12-02 with total page 1034 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mechanistic Studies of DNA Replication and Genetic Recombination emerged from a symposium on DNA replication and genetic recombination held from March 16-21, 1980 in Keystone, Colorado. The event featured 30 plenary session talks, 13 workshop discussion groups, and the 210 poster sessions. The studies described in this book are paving the way for the elucidation of other basic genetic mechanisms, including ""new"" areas in molecular genetics such as those of eukaryotic gene expression and the transposition of mobile genetic elements. This book is divided into 10 parts: summaries of workshop discussion groups (Part I); studies on eukaryotic model systems for DNA replication (Part II); studies on bacterial replication origins (Part III); studies on replication origins of bacterial phages and plasmids (Part IV); studies on eukaryotic replication origins (Part V); studies on prokaryotic replication enzymology (Part VI); studies on eukaryotic replication enzymology (Part VII); studies on the fidelity of DNA replication (Part VIII); studies on DNA topoisomerases (Part IX); and studies of genetic recombination mechanisms (Part X).
Author : Nicholas R. Cozzarelli
Publisher : John Wiley & Sons
ISBN 13 : 9780471834977
Total Pages : 902 pages
Book Rating : 4.8/5 (349 download)
Download or read book Mechanisms of DNA Replication and Recombination written by Nicholas R. Cozzarelli and published by John Wiley & Sons. This book was released on 1985-04-01 with total page 902 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Rhoda Grell
Publisher : Springer Science & Business Media
ISBN 13 : 1468421336
Total Pages : 443 pages
Book Rating : 4.4/5 (684 download)
Download or read book Mechanisms in Recombination written by Rhoda Grell and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains the papers presented at the Twenty-Seventh Annual Biology Division Research Conference which was held April 1-4, 1974 in Gatlinburg, Tennessee. The topic of the symposium was Mechanisms in Recombination and it follows by exactly twenty years the previous Gatlinburg Symposium on Genetic Recombination. During this interval, and the preceding years as well, the process of recombination has remained a central and tantalizing problem for geneticists. The subject assumes added significance with the recent appeal by a committee of leading scientists for a moratorium on the construction of certain types of recombinant molecules. That autonomously replicating molecules linking portions of pro karyotic and eukaryotic DNA can now be produced in vitro attests to the technical advances that have taken place in this field. Nevertheless, the details underlying the process in vivo continue to be elusive. This symposium brought together individuals studying recombi nation in organisms as widely separated as bacteriophage and mammals and using disciplinary approaches of comparable diversity. Conse quently the present volume summarizes much of current strategies and concepts concerning the subject. The meeting was sponsored by the Biology Division of the Oak Ridge National Laboratory (operated by the Union Carbide Corporation for the U. S. Atomic Energy Commission) with the support and encour agement of its director, H. I. Adler. The organizing committee was chaired by J. K. Setlow and included R. F. Grell, R. D. Hotchkiss and E. Volkin. Special thanks are due to the speakers, to I. R.
Author : David Stuart
Publisher : BoD – Books on Demand
ISBN 13 : 953510991X
Total Pages : 502 pages
Book Rating : 4.5/5 (351 download)
Download or read book The Mechanisms of DNA Replication written by David Stuart and published by BoD – Books on Demand. This book was released on 2013-02-20 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA replication is a fundamental part of the life cycle of all organisms. Not surprisingly many aspects of this process display profound conservation across organisms in all domains of life. The chapters in this volume outline and review the current state of knowledge on several key aspects of the DNA replication process. This is a critical process in both normal growth and development and in relation to a broad variety of pathological conditions including cancer. The reader will be provided with new insights into the initiation, regulation, and progression of DNA replication as well as a collection of thought provoking questions and summaries to direct future investigations.
Author : Charles C. Richardson
Publisher : Wiely-Liss
ISBN 13 :
Total Pages : 448 pages
Book Rating : 4.:/5 (45 download)
Download or read book Molecular Mechanisms in DNA Replication and Recombination written by Charles C. Richardson and published by Wiely-Liss. This book was released on 1990 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: "DNA to DNA transitions are spectacular events involving phenomenal biochemical and topological complexity and astounding requisites for precision and control. Molecular Mechanisms in DNA Replication and Recombination offers a detailed understanding of the molecular mechanisms of DNA replication and recombination and their regulation. The book represents a thorough picture of the various topological forms that the DNA double helix can assume, and the way in which these forms can recognize and interact with their cognate bindings proteins and enzymes. This volume features the work of X-ray crystallographers, structural chemists, and nucleic acid enzymologists to promote the cross-fertilization of ideas, experimental approaches, and techniques. It assesses major advances in the field such as: the ways in which replication od duplex DNA genomes, both prokaryotic and eukaryotic are initiated, the replication potential of SV40 (the state of phosphorylation of large T antigen and presumably its host cell analogue) and ori C (the functional interaction of the DNA protein with phospholipids, and presumably the cell membrane), the structure and dynamics of DNA polymerase action, and the molecular mechanism of site specific and homologous recombination. Molecular Mechanisms in DNA Replication and Recombination is of importance to scientists involved in nucleic acid research, molecular biology, enzymology, and celluar biochemistry." --
Author :
Publisher : Academic Press
ISBN 13 : 0128144300
Total Pages : 610 pages
Book Rating : 4.1/5 (281 download)
Download or read book Mechanisms of DNA Recombination and Genome Rearrangements: Methods to Study Homologous Recombination written by and published by Academic Press. This book was released on 2018-02-17 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mechanisms of DNA Recombination and Genome Rearrangements: Methods to Study Homologous Recombination, Volume 600, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Homologous genetic recombination remains the most enigmatic process in DNA metabolism. The molecular machines of recombination preserve the integrity of the genetic material in all organisms and generate genetic diversity in evolution. The same molecular machines that support genetic integrity by orchestrating accurate repair of the most deleterious DNA lesions, however, also promote survival of cancerous cells and emergence of radiation and chemotherapy resistance. This two-volume set offers a comprehensive set of cutting edge methods to study various aspects of homologous recombination and cellular processes that utilize the enzymatic machinery of recombination The chapters are written by the leading researches and cover a broad range of topics from the basic molecular mechanisms of recombinational proteins and enzymes to emerging cellular techniques and drug discovery efforts. Contributions by the leading experts in the field of DNA repair, recombination, replication and genome stability Documents cutting edge methods
Author :
Publisher : Academic Press
ISBN 13 : 0128139803
Total Pages : 436 pages
Book Rating : 4.1/5 (281 download)
Download or read book Mechanisms of DNA Recombination and Genome Rearrangements: Intersection Between Homologous Recombination, DNA Replication and DNA Repair written by and published by Academic Press. This book was released on 2018-03-06 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mechanisms of DNA Recombination and Genome Rearrangements: Intersection between Homologous Recombination, DNA Replication and DNA Repair, Volume 601, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Homologous genetic recombination remains the most enigmatic process in DNA metabolism. The molecular machines of recombination preserve the integrity of the genetic material in all organisms and generate genetic diversity in evolution. The same molecular machines that support genetic integrity by orchestrating accurate repair of the most deleterious DNA lesions, however, also promote survival of cancerous cells and emergence of radiation and chemotherapy resistance. This two-volume set offers a comprehensive set of cutting edge methods to study various aspects of homologous recombination and cellular processes that utilize the enzymatic machinery of recombination. The chapters are written by the leading researches and cover a broad range of topics from the basic molecular mechanisms of recombinational proteins and enzymes to emerging cellular techniques and drug discovery efforts. contributions by the leading experts in the field of DNA repair, recombination, replication and genome stability documents cutting edge methods
Author : Nicholas R. Cozzarelli
Publisher :
ISBN 13 :
Total Pages : 876 pages
Book Rating : 4.:/5 (878 download)
Download or read book Mechanisms of DNA Replication and Recombination written by Nicholas R. Cozzarelli and published by . This book was released on 1983 with total page 876 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kenneth N Kreuzer
Publisher : World Scientific
ISBN 13 : 9811215715
Total Pages : 438 pages
Book Rating : 4.8/5 (112 download)
Download or read book Replicating And Repairing The Genome: From Basic Mechanisms To Modern Genetic Technologies written by Kenneth N Kreuzer and published by World Scientific. This book was released on 2020-03-16 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: Replicating and Repairing the Genome provides a concise overview of the fields of DNA replication and repair. The book is particularly appropriate for graduate students and advanced undergraduates, and scientists entering the field or working in related fields. The breadth of information regarding DNA replication and repair is vast and often difficult to absorb, with terminology that differs between experimental systems and with complex interconnections of these processes with other cellular pathways. This book provides simple conceptual descriptions of replication and repair pathways using mostly generic protein names, laying out the logic for how the pathways function and highlighting fascinating aspects of the underlying biochemical mechanisms and biology. The book incorporates extensive and informative diagrams and figures, as well as descriptions of a number of carefully chosen experiments that had major influences in the field.The process of DNA replication is explained progressively by starting with the system of a simple bacterial virus that uses only a few proteins, followed by the well-understood bacterial (E coli) system, and then culminating with the more complex eukaryotic systems. In the second half of the book, individual chapters cover key areas of DNA repair — postreplication repair of mismatches and incorporated ribonucleotides, direct damage reversal, excision repair, and DNA break repair, as well as the related areas of DNA damage tolerance (including translesion DNA polymerases) and DNA damage responses. The book closes with chapters that describe the huge impact of DNA replication and repair on aspects of human health and on modern biotechnology.
Author : Hisao Masai
Publisher : Springer
ISBN 13 : 9811069557
Total Pages : 581 pages
Book Rating : 4.8/5 (11 download)
Download or read book DNA Replication written by Hisao Masai and published by Springer. This book was released on 2018-01-22 with total page 581 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the latest trends and future directions of DNA replication research. The contents reflect upon the principles that have been established through the genetic and enzymatic studies of bacterial, viral, and cellular replication during the past decades. The book begins with a historical overview of the studies on eukaryotic DNA replication by Professor Thomas Kelly, a pioneer of the field. The following chapters include genome-wide studies of replication origins and initiation factor binding, as well as the timing of DNA replications, mechanisms of initiation, DNA chain elongation and termination of DNA replication, the structural basis of functions of protein complexes responsible for execution of DNA replication, cell cycle-dependent regulation of DNA replication, the nature of replication stress and cells’ strategy to deal with the stress, and finally how all these phenomena are interconnected to genome instability and development of various diseases. By reviewing the existing concepts ranging from the old principles to the newest ideas, the book gives readers an opportunity to learn how the classical replication principles are now being modified and new concepts are being generated to explain how genome DNA replication is achieved with such high adaptability and plasticity. With the development of new methods including cryoelectron microscopy analyses of huge protein complexes, single molecular analyses of initiation and elongation of DNA replication, and total reconstitution of eukaryotic DNA replication with purified factors, the field is enjoying one of its most exciting moments, and this highly timely book conveys that excitement to all interested readers.
Author : Roger J. A. Grand
Publisher : Garland Science
ISBN 13 : 0429876548
Total Pages : 368 pages
Book Rating : 4.4/5 (298 download)
Download or read book DNA Repair and Replication written by Roger J. A. Grand and published by Garland Science. This book was released on 2018-09-03 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA Repair and Replication brings together contributions from active researchers. The first part of this book covers most aspects of the DNA damage response, emphasizing the relationship to replication stress. The second part concentrates on the relevance of this to human disease, with particular focus on both the causes and treatments which make use of DNA Damage Repair (DDR) pathways. Key Selling Features: Chapters written by leading researchers Includes description of replication processes, causes of damage, and methods of repair
Author : Wiesława Widłak
Publisher : Springer
ISBN 13 : 3642453619
Total Pages : 159 pages
Book Rating : 4.6/5 (424 download)
Download or read book Molecular Biology - Not Only for Bioinformaticians written by Wiesława Widłak and published by Springer. This book was released on 2013-12-05 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioinformatics, which can be defined as the application of computer science and information technology to the field of biology and medicine, has been rapidly developing over the past few decades. It generates new knowledge as well as the computational tools to create that knowledge. Understanding the basic processes in living organisms is therefore indispensable for bioinformaticians. This book addresses beginners in molecular biology, especially computer scientists who would like to work as bioinformaticians. It presents basic processes in living organisms in a condensed manner. Additionally, principles of several high-throughput technologies in molecular biology, which need the assistance of bioinformaticians, are explained from a biological point of view. It is structured in the following 9 chapters: cells and viruses; protein structure and function; nucleic acids; DNA replication, mutations, and repair; transcription and posttranscriptional processes; synthesis and posttranslational modifications of proteins; cell division; cell signaling pathways; and high-throughput technologies in molecular biology.
Author : Philip Hanawalt
Publisher : Elsevier
ISBN 13 : 032314232X
Total Pages : 832 pages
Book Rating : 4.3/5 (231 download)
Download or read book DNA Repair Mechanisms written by Philip Hanawalt and published by Elsevier. This book was released on 2012-12-02 with total page 832 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA Repair Mechanisms is an account of the proceedings at a major international conference on DNA Repair Mechanisms held at Keystone, Colorado on February 1978. The conference discusses through plenary sessions the overall standpoint of DNA repair. The papers presented and other important documents, such as short summaries by the workshop session conveners, comprise this book. The compilation describes the opposing views, those that agree and dispute about certain topic areas. This book, divided into 15 parts, is arranged according to the proceedings in the conference. The plenary sessions are grouped with the related workshop and poster manuscripts. The first two parts generally tackle repair in terms of its identification and quantification, as well as the models, systems, and perspectives it utilizes. The following parts discuss the various types of repair including base excision, nucleotide excision repair in bacteria, excision repair in mammalian cells, inducible/error-prone repair in prokaryotes, and strand break repair in mammalian cells among others. This reference material looks into the replicative bypass mechanisms in mammalian cells, viral probes, and hereditary repair defects. It explains repair deficiency and human disease, as well as mutagenesis and carcinogenesis. The last part of this book deals with the consequences and effects of DNA repair. This volume is a helpful source of reference for students, teachers, scientists, and researchers in the different fields of genetics, radiology, biochemistry, and environmental biology.
Author : Jelena Kusic-Tisma
Publisher : BoD – Books on Demand
ISBN 13 : 9533072598
Total Pages : 322 pages
Book Rating : 4.5/5 (33 download)
Download or read book Fundamental Aspects of DNA Replication written by Jelena Kusic-Tisma and published by BoD – Books on Demand. This book was released on 2011-09-26 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA replication, the process of copying one double stranded DNA molecule to produce two identical copies, is at the heart of cell proliferation. This book highlights new insights into the replication process in eukaryotes, from the assembly of pre-replication complex and features of DNA replication origins, through polymerization mechanisms, to propagation of epigenetic states. It also covers cell cycle control of replication initiation and includes the latest on mechanisms of replication in prokaryotes. The association between genome replication and transcription is also addressed. We hope that readers will find this book interesting, helpful and inspiring.
