Mechanisms of Dietary Restriction in Aging and Disease

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Publisher : Lulu.com
ISBN 13 : 0359617298
Total Pages : 206 pages
Book Rating : 4.3/5 (596 download)

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Book Synopsis Mechanisms of Dietary Restriction in Aging and Disease by : Charles V. Mobbs

Download or read book Mechanisms of Dietary Restriction in Aging and Disease written by Charles V. Mobbs and published by Lulu.com. This book was released on with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mechanisms of Dietary Restriction in Aging and Disease

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Publisher :
ISBN 13 : 9783318013900
Total Pages : 0 pages
Book Rating : 4.0/5 (139 download)

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Book Synopsis Mechanisms of Dietary Restriction in Aging and Disease by : C.V. Mobbs

Download or read book Mechanisms of Dietary Restriction in Aging and Disease written by C.V. Mobbs and published by . This book was released on 2006 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dietary restriction uniquely and robustly increases maximum lifespan and greatly reduces age-related diseases in many species, including yeast, flies, nematodes, and mammals. To study mechanisms mediating the protective effects of dietary restriction, the National Institute of Aging convened a program involving several leading gerontological laboratories. Results from many of these, as well as from other leading research institutions in the field, are presented in this book. The first three papers address general molecular mechanisms, derived in part from recent DNA microarray studies, that may mediate protective effects of dietary restriction. The subsequent articles examine specific model systems, including flies, nematodes and non-human primates, that have provided exciting new information about these mechanisms. Finally, mechanisms of dietary restriction mediating protective effects against cancer and neurological diseases are discussed. In addition to gerontologists and geriatricians, many other medical and nonmedical professionals in the field will find a great wealth of information on possible interventions that may ameliorate age-related diseases.

Caloric Restriction: A Key to Understanding and Modulating Aging

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Author :
Publisher : Elsevier
ISBN 13 : 0080528422
Total Pages : 193 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Caloric Restriction: A Key to Understanding and Modulating Aging by : E.J. Masoro

Download or read book Caloric Restriction: A Key to Understanding and Modulating Aging written by E.J. Masoro and published by Elsevier. This book was released on 2002-12-20 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: For many years, it has been known that when rats and mice are given a reduced amount of food, their life span is increased and they remain healthy and vigorous at advanced ages. What is the reason for this change in the usual pattern of aging? The evidence is overwhelming that the life extension results from a slowing of aging processes. And the factor responsible is the decrease in caloric intake. The obvious question: How does this factor work? A good question - and the reason that research on the anti-aging action of caloric restriction is today one of the most studied research areas in biological gerontology. For it is felt that if the biological mechanisms of the anti-aging action of caloric restriction can be uncovered, we would gain an understanding of the basic nature of aging processes, which would, in turn, yield possible interventions in human aging. This book aims to provide the growing number of researchers in this field (faculty, postdoctoral trainees, and graduate students) with a detailed knowledge of what is known about caloric restriction within the frame of gerontology, as well as insights on future of this field.

Calorie Restriction, Aging and Longevity

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9048185564
Total Pages : 327 pages
Book Rating : 4.0/5 (481 download)

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Book Synopsis Calorie Restriction, Aging and Longevity by : Arthur V. Everitt

Download or read book Calorie Restriction, Aging and Longevity written by Arthur V. Everitt and published by Springer Science & Business Media. This book was released on 2010-06-14 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: Food or calorie restriction has been shown in many short-lived animals and the rhesus monkey to prolong life-span. Life-long nutrition studies are not possible in humans because of their long survival. Studies over two to six years in healthy adult humans have, however, shown that a 20% reduction in food or calorie intake slows many indices of normal and disease-related aging. Thus, it is widely believed that long-term reduction in calorie or food intake will delay the onset of age-related diseases such as heart disease, diabetes and cancer, and so prolong life. Over the last 20 or more years there has been a progressive rise in food intake in many countries of the world, accompanied by a rising incidence of obesity. Thus our increasing food and calorie intake has been linked to the rising incidence of cardiovascular disease and diabetes in early adult life. It is accepted that overeating, accompanied by reduced physical exercise, will lead to more age-related diseases and shortening of life-span. The answer is to reduce our calorie intake, improve our diet, and exercise more. But calorie restriction is extremely difficult to maintain for long periods. How then can we solve this problem? Edited by a team of highly distinguished academics, this book provides the latest information on the beneficial effects of calorie restriction on health and life-span. This book brings us closer to an understanding at the molecular, cellular and whole organism level of the way forward.

Mechanisms of Dietary Restriction in Aging and Disease

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Author :
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 380558170X
Total Pages : 207 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis Mechanisms of Dietary Restriction in Aging and Disease by : Charles V. Mobbs

Download or read book Mechanisms of Dietary Restriction in Aging and Disease written by Charles V. Mobbs and published by Karger Medical and Scientific Publishers. This book was released on 2007 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dietary restriction uniquely and robustly increases maximum lifespan and greatly reduces age-related diseases in many species, including yeast, flies, nematodes, and mammals. To study mechanisms mediating the protective effects of dietary restriction, the

The Retardation of Aging and Disease by Dietary Restriction

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Publisher : Charles C Thomas Pub Limited
ISBN 13 : 9780398054960
Total Pages : 436 pages
Book Rating : 4.0/5 (549 download)

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Book Synopsis The Retardation of Aging and Disease by Dietary Restriction by : Richard Weindruch

Download or read book The Retardation of Aging and Disease by Dietary Restriction written by Richard Weindruch and published by Charles C Thomas Pub Limited. This book was released on 1988-01-01 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Providing Healthy and Safe Foods As We Age

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Publisher : National Academies Press
ISBN 13 : 0309158834
Total Pages : 192 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Providing Healthy and Safe Foods As We Age by : Institute of Medicine

Download or read book Providing Healthy and Safe Foods As We Age written by Institute of Medicine and published by National Academies Press. This book was released on 2010-11-29 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: Does a longer life mean a healthier life? The number of adults over 65 in the United States is growing, but many may not be aware that they are at greater risk from foodborne diseases and their nutritional needs change as they age. The IOM's Food Forum held a workshop October 29-30, 2009, to discuss food safety and nutrition concerns for older adults.

The Effect of Calorie Restriction and Intermittent Fasting on Health and Disease

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Publisher : MDPI
ISBN 13 : 3039438379
Total Pages : 186 pages
Book Rating : 4.0/5 (394 download)

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Book Synopsis The Effect of Calorie Restriction and Intermittent Fasting on Health and Disease by : Hae-Young Chung

Download or read book The Effect of Calorie Restriction and Intermittent Fasting on Health and Disease written by Hae-Young Chung and published by MDPI. This book was released on 2021-01-29 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent biochemical studies indicate that calorie restriction (CR) is a widely accepted method for anti-aging intervention. CR and intermittent fasting (IF), which involves reduced calories but proper nutritional intake during specific periods, are interventions that can consistently promote health benefits, delay biological aging, and extend both average and maximal lifespan. Furthermore, CR can modulate age-related diseases such as Alzheimer’s disease, atherosclerosis, diabetes, obesity, cancer, and others. Advances in omics technologies have provided a technical breakthrough that enabled the investigation of DNA, RNA, proteins, and other cellular molecules and their comprehensive interactions in a biological context. Nowadays, it is possible to analyze and integrate biological processes that occur in aging systems at the molecular level using state-of-the-art techniques such as next-generation sequencing (NGS), proteomics, lipidomics, metabolomics, and epigenomics. Omics technology and systems gerontology provide predictive information on CR effects, molecular mechanisms, and pathways underlying the anti-aging actions of CR and IF. This Special Issue, “The effects of calorie restriction and intermittent fasting on health and disease”, focuses on the effects of calorie restriction and intermittent fasting on age-related inflammation, autophagy, metabolism, longevity, mitochondrial function, and age-related diseases.

Modulation of Aging Processes by Dietary Restriction

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Publisher : CRC PressI Llc
ISBN 13 : 9780849349942
Total Pages : 281 pages
Book Rating : 4.3/5 (499 download)

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Book Synopsis Modulation of Aging Processes by Dietary Restriction by : Byung Pal Yu

Download or read book Modulation of Aging Processes by Dietary Restriction written by Byung Pal Yu and published by CRC PressI Llc. This book was released on 1994 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biological Effects of Dietary Restriction

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Publisher : Springer Science & Business Media
ISBN 13 : 3642581811
Total Pages : 361 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Biological Effects of Dietary Restriction by : Lawrence Fishbein

Download or read book Biological Effects of Dietary Restriction written by Lawrence Fishbein and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: How does dietary restriction affect the physiological and biochemical state of laboratory animals? How will the present conclusions affect further research? What are the implications for human health and safety assessment? These are the main questions asked in this book by leading international researchers. After a first look at feeding regimens and diets of laboratory animals, the book elaborates on a variety of age-associated toxicological and pathological endpoints including tumor development. The following sections detail the underlying mechanisms which may induce the broad spectrum of physiological and biochemical changes. This summary of current multidisciplinary research will enhance understanding of the practical applications and implications of dietary restriction.

Nutritional Approaches To Aging Research

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Publisher : CRC Press
ISBN 13 : 1351092022
Total Pages : 391 pages
Book Rating : 4.3/5 (51 download)

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Book Synopsis Nutritional Approaches To Aging Research by : Moment

Download or read book Nutritional Approaches To Aging Research written by Moment and published by CRC Press. This book was released on 2018-01-18 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: The general plan of this volume, Nutritional Approaches to Aging Research is for each chapter to present first a reasonably succinct state-of-the-art appraisal of present knowledge in the particular field or problem covered. This will vary considerable depending on the subject matter. Following this, each chapter will focus on the problems and pitfalls, both conceptual and technological, of work in the particular field and, no less important, present some of the opportunities and implications of work in that particular area.

Nutrition Across the Lifespan for Healthy Aging

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Publisher : National Academies Press
ISBN 13 : 0309457513
Total Pages : 169 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Nutrition Across the Lifespan for Healthy Aging by : National Academies of Sciences, Engineering, and Medicine

Download or read book Nutrition Across the Lifespan for Healthy Aging written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-05-11 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: In September 2016, the National Academies of Sciences, Engineering, and Medicine convened a workshop to examine trends and patterns in aging and factors related to healthy aging in the United States, with a focus on nutrition, and how nutrition can sustain and promote healthy aging, not just in late adulthood, but beginning in pregnancy and early childhood and extending throughout the lifespan. Participants discussed the role of nutrition in the aging process at various stages in life, changes in organ systems over the lifespan and changes that occur with age related to cognitive, brain, and mental health, and explored opportunities to move forward in promoting healthy aging in the United States. This publication summarizes the presentations and discussions from the workshop.

Geriatric Gastroenterology

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Publisher : Springer Science & Business Media
ISBN 13 : 1441916237
Total Pages : 660 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Geriatric Gastroenterology by : C. S. Pitchumoni

Download or read book Geriatric Gastroenterology written by C. S. Pitchumoni and published by Springer Science & Business Media. This book was released on 2012-07-26 with total page 660 pages. Available in PDF, EPUB and Kindle. Book excerpt: As aging trends in the United States and Europe in particular are strongly suggestive of increasingly older society, it would be prudent for health care providers to better prepare for such changes. By including physiology, disease, nutrition, pharmacology, pathology, radiology and other relevant associated topics, Geriatric Gastroenterology fills the void in the literature for a volume devoted specifically to gastrointestinal illness in the elderly. This unique volume includes provision of training for current and future generations of physicians to deal with the health problems of older adults. It will also serve as a comprehensive guide to practicing physicians for ease of reference. Relevant to the geriatric age group, the volume covers epidemiology, physiology of aging, gastrointestinal physiology, pharmacology, radiology, pathology, motility disorders, luminal disorders, hepato-biliary disease, systemic manifestations, neoplastic disorders, gastrointestinal bleeding, cancer and medication related interactions and adverse events, all extremely common in older adults; these are often hard to evaluate and judge, especially considering the complex aging physiology. All have become important components of modern medicine. Special emphasis is be given to nutrition and related disorders. Capsule endoscopy and its utility in the geriatric population is also covered. Presented in simple, easy to read style, the volume includes numerous tables, figures and key points enabling ease of understanding. Chapters on imaging and pathology are profusely illustrated. All chapters are written by specialists and include up to date scientific information. Geriatric Gastroenterology is of great utility to residents in internal medicine, fellows in gastroenterology and geriatric medicine as well as gastroenterologists, geriatricians and practicing physicians including primary care physicians caring for older adults.

Brain Aging

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Publisher : CRC Press
ISBN 13 : 9781420005523
Total Pages : 408 pages
Book Rating : 4.0/5 (55 download)

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Book Synopsis Brain Aging by : David R. Riddle

Download or read book Brain Aging written by David R. Riddle and published by CRC Press. This book was released on 2007-04-19 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recognition that aging is not the accumulation of disease, but rather comprises fundamental biological processes that are amenable to experimental study, is the basis for the recent growth of experimental biogerontology. As increasingly sophisticated studies provide greater understanding of what occurs in the aging brain and how these changes occur

Nutrition, Food and Diet in Ageing and Longevity

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Publisher : Springer Nature
ISBN 13 : 3030830179
Total Pages : 643 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Nutrition, Food and Diet in Ageing and Longevity by : Suresh I. S. Rattan

Download or read book Nutrition, Food and Diet in Ageing and Longevity written by Suresh I. S. Rattan and published by Springer Nature. This book was released on 2021-10-03 with total page 643 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited volume is a compilation of 30 articles discussing what constitutes food for health and longevity. The aim is to provide up-to-date information, insights, and future tendencies in the ongoing scientific research about nutritional components, food habits and dietary patterns in different cultures. The health-sustaining and health-promoting effects of food are certainly founded in its overall composition of macronutrients and micronutrients. However, the consumption of these nutrients is normally in the form of raw or prepared food from the animal and plant sources. The book is divided into four parts and a conclusion, and successfully convenes the well-established information and knowledge, along with the personal views of a diversified group of researchers and academicians on the multifaceted aspects of nutrition, food and diet. The first part reviews the scientific information about proteins, carbohydrates, fats and oils, micronutrients, pro- and pre-biotics, and hormetins, along with a discussion of the evolutionary principles and constraints about what is optimal food, if any. The second part discusses various kinds of foods and food supplements with respect to their claimed benefits for general health and prevention of some diseases. The third part brings in the cultural aspects, such as what are the principles of healthy eating according to the traditional Chinese and Indian systems, what is the importance of mealing times and daily rhythms, and how different cultures have developed different folk wisdoms for eating for health, longevity and immortality. In the part four, various approaches which are either already in practice or are still in the testing and research phases are discussed and evaluated critically, for example intermittent fasting and calorie restriction, food-based short peptides, senolytics, Ayurvedic compounds, optimal food for old people, and food for the prevention of obesity and other metabolic disorders. The overreaching aim of this book is to inform, inspire and encourage students, researchers, educators and medical health professionals thinking about food and food habits in a holistic context of our habits, cultures and patterns. Food cannot be reduced to a pill of nutritional components. Eating food is a complex human behavior culturally evolved over thousands of years. Perhaps the old adage “we are what we eat” needs to be modified to “we eat what we are”.

Principles of Nutrigenetics and Nutrigenomics

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Publisher : Academic Press
ISBN 13 : 0128045876
Total Pages : 586 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Principles of Nutrigenetics and Nutrigenomics by : Raffaele De Caterina

Download or read book Principles of Nutrigenetics and Nutrigenomics written by Raffaele De Caterina and published by Academic Press. This book was released on 2019-09-22 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Nutrigenetics and Nutrigenomics: Fundamentals for Individualized Nutrition is the most comprehensive foundational text on the complex topics of nutrigenetics and nutrigenomics. Edited by three leaders in the field with contributions from the most well-cited researchers conducting groundbreaking research in the field, the book covers how the genetic makeup influences the response to foods and nutrients and how nutrients affect gene expression. Principles of Nutrigenetics and Nutrigenomics: Fundamentals for Individualized Nutrition is broken into four parts providing a valuable overview of genetics, nutrigenetics, and nutrigenomics, and a conclusion that helps to translate research into practice. With an overview of the background, evidence, challenges, and opportunities in the field, readers will come away with a strong understanding of how this new science is the frontier of medical nutrition. Principles of Nutrigenetics and Nutrigenomics: Fundamentals for Individualized Nutrition is a valuable reference for students and researchers studying nutrition, genetics, medicine, and related fields. Uniquely foundational, comprehensive, and systematic approach with full evidence-based coverage of established and emerging topics in nutrigenetics and nutrigenomics Includes a valuable guide to ethics for genetic testing for nutritional advice Chapters include definitions, methods, summaries, figures, and tables to help students, researchers, and faculty grasp key concepts Companion website includes slide decks, images, questions, and other teaching and learning aids designed to facilitate communication and comprehension of the content presented in the book

Models, Molecules and Mechanisms in Biogerontology

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Author :
Publisher :
ISBN 13 : 9789811335860
Total Pages : pages
Book Rating : 4.3/5 (358 download)

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Book Synopsis Models, Molecules and Mechanisms in Biogerontology by : Pramod C. Rath

Download or read book Models, Molecules and Mechanisms in Biogerontology written by Pramod C. Rath and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines the basic cellular and molecular mechanisms associated with aging. It comprehensively describes the genetic, epigenetic, biochemical and metabolic regulation of aging, as well as some important age-related diseases. Divided into two major sections, it takes readers through the various aspects of aging in a story-like manner and suggests various interventions for healthy aging, such as dietary restriction, regular exercise, nutrition and maintaining a balanced and a non-stressful lifestyle. It describes the implications of aging on the nervous system, metabolism, immunity and stem cells as well as care for the elderly. The book is an ideal companion for both new and established researchers in the field and is also useful for educators, clinicians and policy makers.