Mechanisms And Genetics Of Neurodevelopmental Cognitive Disorders

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Mechanisms and Genetics of Neurodevelopmental Cognitive Disorders

Author : Moyra Smith
Publisher : Academic Press
ISBN 13 : 0128232528
Total Pages : 308 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Mechanisms and Genetics of Neurodevelopmental Cognitive Disorders by : Moyra Smith

Download or read book Mechanisms and Genetics of Neurodevelopmental Cognitive Disorders written by Moyra Smith and published by Academic Press. This book was released on 2021-04-25 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mechanisms and Genetics of Neurodevelopmental Cognitive Disorders connects neurodevelopment with genetics and behavior to better understand the underlying factors leading to cognitive neurodevelopmental disorders. This book focuses on mechanisms of disease and follows the development of specific brain regions, functions, and gene expression to causes and processes in autism, attention deficit disorder, and learning disabilities. Topics include brain mapping, brain plasticity, epigenetics, neuroimmunology, and many other factors that influence the development of these diseases. This book will promote understanding of recent investigations and developments related to brain development from fetal life onward with specific relevance to neurodevelopmental cognitive disorders and conditions. This is an essential reference for anyone who is looking to learn more about different aspects of neurodevelopment and emerging concepts in psychiatric disorders. - Discusses links between brain development, gene expression, and brain function - Covers neural stem cells, proliferation, migration, differentiation, and neurogenesis - Includes brain mapping, brain plasticity, epigenetics, neuroimmunology, and more - Provides insight into causation and brain function in autism, attention deficit disorder, and learning disabilities - Examines impact of society and environmental factors on mental health

Neurodevelopmental Disorders

Author : Helen Tager-Flusberg
Publisher : MIT Press
ISBN 13 : 9780262201162
Total Pages : 634 pages
Book Rating : 4.2/5 (11 download)

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Book Synopsis Neurodevelopmental Disorders by : Helen Tager-Flusberg

Download or read book Neurodevelopmental Disorders written by Helen Tager-Flusberg and published by MIT Press. This book was released on 1999 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt: Content Description #"A Bradford Book."#Includes bibliographical references and index.

Treatment of Neurodevelopmental Disorders

Author : Randi Jenssen Hagerman
Publisher : Oxford University Press, USA
ISBN 13 : 019993780X
Total Pages : 401 pages
Book Rating : 4.1/5 (999 download)

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Book Synopsis Treatment of Neurodevelopmental Disorders by : Randi Jenssen Hagerman

Download or read book Treatment of Neurodevelopmental Disorders written by Randi Jenssen Hagerman and published by Oxford University Press, USA. This book was released on 2014 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: This cutting-edge book brings advances in genetics, neurobiology, and psychopharmacology to the clinic to enhance treatment for neurodevelopmental disorders. Significant progress has been made in identifying the neurobiological mechanisms of several disorders and targeted treatments are modifying the outcome of these disorders. However, the ability to utilize this knowledge has not been summarized in one place for the practicing clinician. This book will fill that gap by providing the theoretical underpinnings and the latest advances in targeted treatments. Several neurodevelopmental disorders are reviewed in detail including clinical features and behavioral phenotypes, standard treatments and new targeted treatments based on the latest advances in neurobiology and the animal model studies that have lead to new treatments. The disorders covered include psychiatric disorders: schizophrenia, depression, autism and ADHD; single gene disorders including Tuberous Sclerosis, Fragile X Syndrome and fragile X- associated disorders, Angelman Syndrome, PKU, and Muscular Dystrophies; and complex genetic disorders such as Down syndrome. This book also highlights the commonalities across disorders and new genetic and molecular concepts in an easy to read format. This is a very exciting time for new targeted treatments and this volume is a landmark treatise on this new age of treatment.

Neurodevelopmental Disorders

Author : Bin Chen
Publisher : Academic Press
ISBN 13 : 0128144106
Total Pages : 428 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Neurodevelopmental Disorders by : Bin Chen

Download or read book Neurodevelopmental Disorders written by Bin Chen and published by Academic Press. This book was released on 2020-05-24 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurodevelopmental Disorders, the latest release in the Comprehensive Developmental Neuroscience series, presents the most thorough coverage available, addressing all aspects on how the nervous system and its components develop. This book brings together the latest research in this rapidly evolving field, with section editors discussing the technological advances that are enabling the pursuit of new research on brain development. This volume focuses on neurodevelopmental disorders in humans and experimental organisms. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms. - Features leading experts in various subfields as section editors and article authors - Presents articles that have been peer reviewed to ensure accuracy, thoroughness and scholarship - Covers disorders of the nervous system that arise through defects in neural development

The Genetics of Neurodevelopmental Disorders

Author : Kevin J. Mitchell
Publisher : John Wiley & Sons
ISBN 13 : 1118524888
Total Pages : 384 pages
Book Rating : 4.1/5 (185 download)

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Book Synopsis The Genetics of Neurodevelopmental Disorders by : Kevin J. Mitchell

Download or read book The Genetics of Neurodevelopmental Disorders written by Kevin J. Mitchell and published by John Wiley & Sons. This book was released on 2015-09-28 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurodevelopmental disorders arise from disturbances to various processes of brain development, which can manifest in diverse ways. They encompass many rare genetic syndromes as well as common, heritable conditions such as intellectual disability, autism, ADHD, schizophrenia and many types of epilepsy. The Genetics of Neurodevelopmental Disorders examines recent revolutionary advances in our understanding of the genetics of these disorders, exploring both basic discoveries and the translation of new findings into the clinical setting. The book begins by examining the genetic architecture and etiology of neurodevelopmental disorders. It describes the striking recent progress in identifying pathogenic mutations, which are grouped here based on the neurodevelopmental processes impacted. Subsequent chapters consider the use of cellular and animal models to elucidate the cascading consequences of such mutations, from molecular and cellular levels to emergent effects on neural circuits, brain systems and subsequent psychological development. The text concludes by examining the important clinical implications of the recent advances in the field, from recognition of the genetic causes in individual patients to development of new treatments and interventions. A timely synthesis, The Genetics of Neurodevelopmental Disorders is a unique and essential resource for neuroscientists, geneticists, neurologists and psychiatrists and an accessible and up-to-date overview for medical and science students.

Neurocognitive Development: Normative Development

Author :
Publisher : Elsevier
ISBN 13 : 0444641513
Total Pages : 534 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Neurocognitive Development: Normative Development by :

Download or read book Neurocognitive Development: Normative Development written by and published by Elsevier. This book was released on 2019-09-22 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is one of a two-volume work on neurocognitive development, focusing separately on normative and non-normative development. The normative volume focuses on neurology, biology, genetics, and psychology of normative cognitive development. It covers the development of intellectual abilities, visual perception, motor function, language, memory, attention, executive function, social cognition, learning abilities, and affect and behavior. The book identifies when and how these functions develop, the genetics and neurophysiology of their operation, and their evaluation and assessment in clinical practice. This book will serve as a comprehensive reference to researchers in cognitive development in neuroscience, psychology, and medicine, as well as to clinicians and allied health professionals focused on developmental disabilities (child neurologists, pediatric neuropsychologists, child psychiatrists, speech and language therapists, and occupational therapists.) - Summarizes research on normative neurocognitive development - Includes intellectual abilities, language, memory, attention, motor function, and more - Discusses genetics and environmental influences on development - Provides interdisciplinary information of use to both researchers and clinicians

Environmental Epigenetics

Author : L. Joseph Su
Publisher : Springer
ISBN 13 : 1447166787
Total Pages : 327 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis Environmental Epigenetics by : L. Joseph Su

Download or read book Environmental Epigenetics written by L. Joseph Su and published by Springer. This book was released on 2015-05-18 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines the toxicological and health implications of environmental epigenetics and provides knowledge through an interdisciplinary approach. Included in this volume are chapters outlining various environmental risk factors such as phthalates and dietary components, life states such as pregnancy and ageing, hormonal and metabolic considerations and specific disease risks such as cancer cardiovascular diseases and other non-communicable diseases. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses.

Autism Spectrum Disorders

Author : Andreas M. Grabrucker
Publisher :
ISBN 13 :
Total Pages : 117 pages
Book Rating : 4.:/5 (128 download)

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Book Synopsis Autism Spectrum Disorders by : Andreas M. Grabrucker

Download or read book Autism Spectrum Disorders written by Andreas M. Grabrucker and published by . This book was released on 2021 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autism spectrum disorders are developmental disorders. Individuals with autism spectrum disorders develop differently. These differences are usually present in social interaction, communication, and sensory processing, and become visible through a wide variety of behavioral responses that differ from individuals without autism spectrum disorders. Despite significant research efforts, the exact causes of autism spectrum disorders remain poorly understood; however, researchers have gained extensive insights into possible pathomechanisms, even at the molecular level of cells. Many diagnostic criteria have been developed, adapted, and improved. The eight chapters in this book highlight the current state-of-the-art in many areas of autism spectrum disorders. Chapter 1 provides an overview of the epidemiology of autism spectrum disorders and the current knowledge of the underlying pathogenic mechanisms. Chapter 2 summarizes the diagnostic criteria and procedures and highlights present and upcoming therapeutic strategies. Chapter 3 reviews the adverse events and trauma in people with autism spectrum disorders. Chapters 4 and 5 focus on atypical sensory processing, and Chapter 6 discusses the genetic overlap of autism spectrum disorders with other neuropsychiatric disorders such as attention deficit hyperactivity disorder (ADHD), depression, and schizophrenia. Chapter 7 focuses on the contribution of abnormalities in mitochondria, and chapter 8 discusses gut-brain interactions and a potential role for microbiota in autism spectrum disorders. This book is aimed primarily at clinicians and scientists, but many areas will also be of interest to the layperson.

From Neurons to Neighborhoods

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309069882
Total Pages : 610 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis From Neurons to Neighborhoods by : National Research Council

Download or read book From Neurons to Neighborhoods written by National Research Council and published by National Academies Press. This book was released on 2000-11-13 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: How we raise young children is one of today's most highly personalized and sharply politicized issues, in part because each of us can claim some level of "expertise." The debate has intensified as discoveries about our development-in the womb and in the first months and years-have reached the popular media. How can we use our burgeoning knowledge to assure the well-being of all young children, for their own sake as well as for the sake of our nation? Drawing from new findings, this book presents important conclusions about nature-versus-nurture, the impact of being born into a working family, the effect of politics on programs for children, the costs and benefits of intervention, and other issues. The committee issues a series of challenges to decision makers regarding the quality of child care, issues of racial and ethnic diversity, the integration of children's cognitive and emotional development, and more. Authoritative yet accessible, From Neurons to Neighborhoods presents the evidence about "brain wiring" and how kids learn to speak, think, and regulate their behavior. It examines the effect of the climate-family, child care, community-within which the child grows.

A Time for Metabolism and Hormones

Author : Paolo Sassone-Corsi
Publisher : Springer
ISBN 13 : 3319270699
Total Pages : 141 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis A Time for Metabolism and Hormones by : Paolo Sassone-Corsi

Download or read book A Time for Metabolism and Hormones written by Paolo Sassone-Corsi and published by Springer. This book was released on 2016-04-04 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent years have seen spectacular advances in the field of circadian biology. These have attracted the interest of researchers in many fields, including endocrinology, neurosciences, cancer, and behavior. By integrating a circadian view within the fields of endocrinology and metabolism, researchers will be able to reveal many, yet-unsuspected aspects of how organisms cope with changes in the environment and subsequent control of homeostasis. This field is opening new avenues in our understanding of metabolism and endocrinology. A panel of the most distinguished investigators in the field gathered together to discuss the present state and the future of the field. The editors trust that this volume will be of use to those colleagues who will be picking up the challenge to unravel how the circadian clock can be targeted for the future development of specific pharmacological strategies toward a number of pathologies.

Jasper's Basic Mechanisms of the Epilepsies

Author : Jeffrey Noebels
Publisher : OUP USA
ISBN 13 : 0199746540
Total Pages : 1258 pages
Book Rating : 4.1/5 (997 download)

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Book Synopsis Jasper's Basic Mechanisms of the Epilepsies by : Jeffrey Noebels

Download or read book Jasper's Basic Mechanisms of the Epilepsies written by Jeffrey Noebels and published by OUP USA. This book was released on 2012-06-29 with total page 1258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.

Management of Genetic Syndromes

Author : Suzanne B. Cassidy
Publisher : John Wiley & Sons
ISBN 13 : 1118210670
Total Pages : 1678 pages
Book Rating : 4.1/5 (182 download)

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Book Synopsis Management of Genetic Syndromes by : Suzanne B. Cassidy

Download or read book Management of Genetic Syndromes written by Suzanne B. Cassidy and published by John Wiley & Sons. This book was released on 2011-09-20 with total page 1678 pages. Available in PDF, EPUB and Kindle. Book excerpt: The bestselling guide to the medical management of common genetic syndromes —now fully revised and expanded A review in the American Journal of Medical Genetics heralded the first edition of Management of Genetic Syndromes as an "unparalleled collection of knowledge." Since publication of the first edition, improvements in the molecular diagnostic testing of genetic conditions have greatly facilitated the identification of affected individuals. This thorough revision of the critically acclaimed bestseller offers original insights into the medical management of sixty common genetic syndromes seen in children and adults, and incorporates new research findings and the latest advances in diagnosis and treatment of these disorders. Expanded to cover five new syndromes, this comprehensive new edition also features updates of chapters from the previous editions. Each chapter is written by an expert with extensive direct professional experience with that disorder and incorporates thoroughly updated material on new genetic findings, consensus diagnostic criteria, and management strategies. Edited by two of the field's most highly esteemed experts, this landmark volume provides: A precise reference of the physical manifestations of common genetic syndromes, clearly written for professionals and families Extensive updates, particularly in sections on diagnostic criteria and diagnostic testing, pathogenesis, and management A tried-and-tested, user-friendly format, with each chapter including information on incidence, etiology and pathogenesis, diagnostic criteria and testing, and differential diagnosis Up-to-date and well-written summaries of the manifestations followed by comprehensive management guidelines, with specific advice on evaluation and treatment for each system affected, including references to original studies and reviews A list of family support organizations and resources for professionals and families Management of Genetic Syndromes, Third Edition is a premier source to guide family physicians, pediatricians, internists, medical geneticists, and genetic counselors in the clinical evaluation and treatment of syndromes. It is also the reference of choice for ancillary health professionals, educators, and families of affected individuals looking to understand appropriate guidelines for the management of these disorders. From a review of the first edition: "An unparalleled collection of knowledge . . . unique, offering a gold mine of information." —American Journal of Medical Genetics

Medical Genetics in Pediatric Practice

Author : American Academy of Pediatrics
Publisher :
ISBN 13 : 9781581104967
Total Pages : 0 pages
Book Rating : 4.1/5 (49 download)

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Book Synopsis Medical Genetics in Pediatric Practice by : American Academy of Pediatrics

Download or read book Medical Genetics in Pediatric Practice written by American Academy of Pediatrics and published by . This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Embodying current Policy of the American Academy of Pediatrics (AAP), this all-new resource provides practice-focused help for addressing virtually any genetics-related issue you're likely to confront. It's replete with expert insights, pediatric-specific solutions, and quick-access aids you won't find anywhere else. Consult this one-stop problem-solver for: - Must-know basics on genetic processes, inheritance patterns, and genetic testing - Concise summaries of common genetic disorders - Recognition, evaluation, diagnosis, and treatment how-to's - Illuminating images of anomalies that may indicate genetic conditions - Case-based examples of ethical issues Here's the how, why, where, and when of pediatric genetic care: - How to recognize diverse genetic disorders - How to take a complete genetic history - How to spot at-risk patients - Why to create a pedigree - When to consider a genetic evaluation - How to conduct genetic screening and testing - How to identify appropriate therapeutic approaches - Where to find critical resources - When to refer to a geneticist - And much more

Autism and William's Syndrome

Author : Helen Tager-Flusberg
Publisher : Psychology Press
ISBN 13 : 9781841690087
Total Pages : 275 pages
Book Rating : 4.6/5 (9 download)

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Book Synopsis Autism and William's Syndrome by : Helen Tager-Flusberg

Download or read book Autism and William's Syndrome written by Helen Tager-Flusberg and published by Psychology Press. This book was released on 2015-10-01 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a new perspective on the development of theory of mind based on an integration of empirical research that has been conducted on autism and William's syndrome.

Neurodevelopmental Disorders

Author : Randi Jenssen Hagerman
Publisher : Oxford University Press
ISBN 13 : 0198028695
Total Pages : 425 pages
Book Rating : 4.1/5 (98 download)

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Book Synopsis Neurodevelopmental Disorders by : Randi Jenssen Hagerman

Download or read book Neurodevelopmental Disorders written by Randi Jenssen Hagerman and published by Oxford University Press. This book was released on 1999-09-16 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurodevelopmental Disorders: Diagnosis and Treatment summarizes a vast body of literature concerning diagnosis and treatment for a variety of neurodevelopmental disorders, including both common and rare conditions. Throughout the book, Dr. Hagerman synthesizes treatment information for many disciplines that work together to provide multi-modality intervention. Psychopharmacological information and recommendations as well as the latest knowledge regarding genetic and diagnostic aspects of each disorder are explained in detail. And all chapters have one or more case studies to model the treatment recommendations, which are enhanced by extensive appendices reviewing educational programs, computer software, and supplementary reading. In addition, a detailed resource list of organizations, educational materials, and internet connections accompanies each chapter. This book not only integrates but also advances our knowledge of treatment, which is of prime importance for clinicians, therapists, educators, and parents.

The Wiley Handbook on What Works for Offenders with Intellectual and Developmental Disabilities

Author : William R. Lindsay
Publisher : John Wiley & Sons
ISBN 13 : 1119316235
Total Pages : 479 pages
Book Rating : 4.1/5 (193 download)

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Book Synopsis The Wiley Handbook on What Works for Offenders with Intellectual and Developmental Disabilities by : William R. Lindsay

Download or read book The Wiley Handbook on What Works for Offenders with Intellectual and Developmental Disabilities written by William R. Lindsay and published by John Wiley & Sons. This book was released on 2019-12-16 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brings together the growing amount of evidence on the assessment and treatment of offenders with intellectual and developmental disabilities. Written by a team of international experts, this comprehensive and informative book provides a contemporary picture of evidence-based practice for offenders with intellectual and developmental disabilities. By adopting a scientist-practitioner position directed at an academic level with practitioner guidelines, it provides a valuable reference source for professionals from allied disciplines who are using or seeking to apply research for this client group. The Wiley Handbook of What Works for Offenders with Intellectual and Developmental Disabilities: An Evidence Based Approach to Theory, Assessment and Treatment is divided into five sections: Introduction, Phenotypes & Genotypes and Offending Behavior, Validated Assessments, Treatment, and Conclusions. The Introduction offers an overview of the entire book and is followed by a second overview covering the ethics of evidence-based practice. After that come chapters on protecting the rights of people with intellectual disabilities in correctional settings, and behavioral and cognitive phenotypes in genetic disorders associated with offending. The third part of the book studies the assessment of individuals with anger and violence issues, inappropriate sexual behavior, alcohol abuse, and emotional difficulties. Next comes a section that looks how to offenders can be treated. The final section discusses future directions and requirements for offenders with intellectual and developmental disabilities. Provides an overview of the ethical challenges and issues faced by those who work with intellectually and developmentally disabled offenders Focuses on proof of treatment effectiveness and validation of assessment methods to direct readers toward "What Works" Features contributions from authors across the entire English-speaking world including the UK, US, Canada, Australia, and New Zealand The Wiley Handbook of What Works for Offenders with Intellectual and Developmental Disabilities: An Evidence Based Approach to Theory, Assessment and Treatment will appeal to all who work in the field of offenders with intellectual and developmental disabilities, including nursing staff, social workers and probation officers, medical and psychology staff, and more.

Homeostatic Control of Brain Function

Author : Detlev Boison
Publisher : Oxford University Press
ISBN 13 : 0199322295
Total Pages : 657 pages
Book Rating : 4.1/5 (993 download)

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Book Synopsis Homeostatic Control of Brain Function by : Detlev Boison

Download or read book Homeostatic Control of Brain Function written by Detlev Boison and published by Oxford University Press. This book was released on 2016 with total page 657 pages. Available in PDF, EPUB and Kindle. Book excerpt: Homeostatic Control of Brain Function offers a broad view of brain health and diverse perspectives for potential treatments, targeting key areas such as mitochondria, the immune system, epigenetic changes, and regulatory molecules such as ions, neuropeptides, and neuromodulators. Loss of homeostasis becomes expressed as a diverse array of neurological disorders. Each disorder has multiple comorbidities - with some crossing over several conditions - and often disease-specific treatments remain elusive. When current pharmacological therapies result in ineffective and inadequate outcomes, therapies to restore and maintain homeostatic functions can help improve brain health, no matter the diagnosis. Employing homeostatic therapies may lead to future cures or treatments that address multiple comorbidities. In an age where brain diseases such as Alzheimer's or Parkinson's are ever present, the incorporation of homeostatic techniques could successfully promote better overall brain health. Key Features include · A focus on the homeostatic controls that significantly depend on the way one lives, eats, and drinks. · Highlights from emerging research in non-pharmaceutical therapies including botanical medications, meditation, diet, and exercise. · Incorporation of homeostatic therapies into existing basic and clinical research paradigms. · Extensive scientific basic and clinical research ranging from molecules to disorders. · Emerging practical information for improving homeostasis. · Examples of homeostatic therapies in preventing and delaying dysfunction. Both editors, Detlev Boison and Susan Masino, bring their unique expertise in homeostatic research to the overall scope of this work. This book is accessible to all with an interest in brain health; scientist, clinician, student, and lay reader alike.