Mathematical Modeling In Biology

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A Biologist's Guide to Mathematical Modeling in Ecology and Evolution

Author : Sarah P. Otto
Publisher : Princeton University Press
ISBN 13 : 1400840910
Total Pages : 745 pages
Book Rating : 4.4/5 (8 download)

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Book Synopsis A Biologist's Guide to Mathematical Modeling in Ecology and Evolution by : Sarah P. Otto

Download or read book A Biologist's Guide to Mathematical Modeling in Ecology and Evolution written by Sarah P. Otto and published by Princeton University Press. This book was released on 2011-09-19 with total page 745 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thirty years ago, biologists could get by with a rudimentary grasp of mathematics and modeling. Not so today. In seeking to answer fundamental questions about how biological systems function and change over time, the modern biologist is as likely to rely on sophisticated mathematical and computer-based models as traditional fieldwork. In this book, Sarah Otto and Troy Day provide biology students with the tools necessary to both interpret models and to build their own. The book starts at an elementary level of mathematical modeling, assuming that the reader has had high school mathematics and first-year calculus. Otto and Day then gradually build in depth and complexity, from classic models in ecology and evolution to more intricate class-structured and probabilistic models. The authors provide primers with instructive exercises to introduce readers to the more advanced subjects of linear algebra and probability theory. Through examples, they describe how models have been used to understand such topics as the spread of HIV, chaos, the age structure of a country, speciation, and extinction. Ecologists and evolutionary biologists today need enough mathematical training to be able to assess the power and limits of biological models and to develop theories and models themselves. This innovative book will be an indispensable guide to the world of mathematical models for the next generation of biologists. A how-to guide for developing new mathematical models in biology Provides step-by-step recipes for constructing and analyzing models Interesting biological applications Explores classical models in ecology and evolution Questions at the end of every chapter Primers cover important mathematical topics Exercises with answers Appendixes summarize useful rules Labs and advanced material available

Mathematical Models in Biology

Author : Leah Edelstein-Keshet
Publisher : SIAM
ISBN 13 : 9780898719147
Total Pages : 629 pages
Book Rating : 4.7/5 (191 download)

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Book Synopsis Mathematical Models in Biology by : Leah Edelstein-Keshet

Download or read book Mathematical Models in Biology written by Leah Edelstein-Keshet and published by SIAM. This book was released on 1988-01-01 with total page 629 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematical Models in Biology is an introductory book for readers interested in biological applications of mathematics and modeling in biology. A favorite in the mathematical biology community, it shows how relatively simple mathematics can be applied to a variety of models to draw interesting conclusions. Connections are made between diverse biological examples linked by common mathematical themes. A variety of discrete and continuous ordinary and partial differential equation models are explored. Although great advances have taken place in many of the topics covered, the simple lessons contained in this book are still important and informative. Audience: the book does not assume too much background knowledge--essentially some calculus and high-school algebra. It was originally written with third- and fourth-year undergraduate mathematical-biology majors in mind; however, it was picked up by beginning graduate students as well as researchers in math (and some in biology) who wanted to learn about this field.

Mathematical Modeling in Systems Biology

Author : Brian P. Ingalls
Publisher : MIT Press
ISBN 13 : 0262545829
Total Pages : 423 pages
Book Rating : 4.2/5 (625 download)

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Book Synopsis Mathematical Modeling in Systems Biology by : Brian P. Ingalls

Download or read book Mathematical Modeling in Systems Biology written by Brian P. Ingalls and published by MIT Press. This book was released on 2022-06-07 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: An introduction to the mathematical concepts and techniques needed for the construction and analysis of models in molecular systems biology. Systems techniques are integral to current research in molecular cell biology, and system-level investigations are often accompanied by mathematical models. These models serve as working hypotheses: they help us to understand and predict the behavior of complex systems. This book offers an introduction to mathematical concepts and techniques needed for the construction and interpretation of models in molecular systems biology. It is accessible to upper-level undergraduate or graduate students in life science or engineering who have some familiarity with calculus, and will be a useful reference for researchers at all levels. The first four chapters cover the basics of mathematical modeling in molecular systems biology. The last four chapters address specific biological domains, treating modeling of metabolic networks, of signal transduction pathways, of gene regulatory networks, and of electrophysiology and neuronal action potentials. Chapters 3–8 end with optional sections that address more specialized modeling topics. Exercises, solvable with pen-and-paper calculations, appear throughout the text to encourage interaction with the mathematical techniques. More involved end-of-chapter problem sets require computational software. Appendixes provide a review of basic concepts of molecular biology, additional mathematical background material, and tutorials for two computational software packages (XPPAUT and MATLAB) that can be used for model simulation and analysis.

Mathematical Models in Biology

Author : Elizabeth Spencer Allman
Publisher : Cambridge University Press
ISBN 13 : 9780521525862
Total Pages : 388 pages
Book Rating : 4.5/5 (258 download)

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Book Synopsis Mathematical Models in Biology by : Elizabeth Spencer Allman

Download or read book Mathematical Models in Biology written by Elizabeth Spencer Allman and published by Cambridge University Press. This book was released on 2004 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: This introductory textbook on mathematical biology focuses on discrete models across a variety of biological subdisciplines. Biological topics treated include linear and non-linear models of populations, Markov models of molecular evolution, phylogenetic tree construction, genetics, and infectious disease models. The coverage of models of molecular evolution and phylogenetic tree construction from DNA sequence data is unique among books at this level. Computer investigations with MATLAB are incorporated throughout, in both exercises and more extensive projects, to give readers hands-on experience with the mathematical models developed. MATLAB programs accompany the text. Mathematical tools, such as matrix algebra, eigenvector analysis, and basic probability, are motivated by biological models and given self-contained developments, so that mathematical prerequisites are minimal.

A Primer in Mathematical Models in Biology

Author : Lee A. Segel
Publisher : SIAM
ISBN 13 : 1611972493
Total Pages : 435 pages
Book Rating : 4.6/5 (119 download)

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Book Synopsis A Primer in Mathematical Models in Biology by : Lee A. Segel

Download or read book A Primer in Mathematical Models in Biology written by Lee A. Segel and published by SIAM. This book was released on 2013-05-09 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: A textbook on mathematical modelling techniques with powerful applications to biology, combining theoretical exposition with exercises and examples.

Mathematical Biology II

Author : James D. Murray
Publisher : Springer Science & Business Media
ISBN 13 : 0387952284
Total Pages : 834 pages
Book Rating : 4.3/5 (879 download)

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Book Synopsis Mathematical Biology II by : James D. Murray

Download or read book Mathematical Biology II written by James D. Murray and published by Springer Science & Business Media. This book was released on 2011-02-15 with total page 834 pages. Available in PDF, EPUB and Kindle. Book excerpt: This richly illustrated third edition provides a thorough training in practical mathematical biology and shows how exciting mathematical challenges can arise from a genuinely interdisciplinary involvement with the biosciences. It has been extensively updated and extended to cover much of the growth of mathematical biology. From the reviews: ""This book, a classical text in mathematical biology, cleverly combines mathematical tools with subject area sciences."--SHORT BOOK REVIEWS

Mathematical Modeling of Biological Processes

Author : Avner Friedman
Publisher : Springer
ISBN 13 : 3319083147
Total Pages : 154 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Mathematical Modeling of Biological Processes by : Avner Friedman

Download or read book Mathematical Modeling of Biological Processes written by Avner Friedman and published by Springer. This book was released on 2014-09-19 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book on mathematical modeling of biological processes includes a wide selection of biological topics that demonstrate the power of mathematics and computational codes in setting up biological processes with a rigorous and predictive framework. Topics include: enzyme dynamics, spread of disease, harvesting bacteria, competition among live species, neuronal oscillations, transport of neurofilaments in axon, cancer and cancer therapy, and granulomas. Complete with a description of the biological background and biological question that requires the use of mathematics, this book is developed for graduate students and advanced undergraduate students with only basic knowledge of ordinary differential equations and partial differential equations; background in biology is not required. Students will gain knowledge on how to program with MATLAB without previous programming experience and how to use codes in order to test biological hypothesis.

A Course in Mathematical Biology

Author : Gerda de Vries
Publisher : SIAM
ISBN 13 : 0898718252
Total Pages : 307 pages
Book Rating : 4.8/5 (987 download)

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Book Synopsis A Course in Mathematical Biology by : Gerda de Vries

Download or read book A Course in Mathematical Biology written by Gerda de Vries and published by SIAM. This book was released on 2006-07-01 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the only book that teaches all aspects of modern mathematical modeling and that is specifically designed to introduce undergraduate students to problem solving in the context of biology. Included is an integrated package of theoretical modeling and analysis tools, computational modeling techniques, and parameter estimation and model validation methods, with a focus on integrating analytical and computational tools in the modeling of biological processes. Divided into three parts, it covers basic analytical modeling techniques; introduces computational tools used in the modeling of biological problems; and includes various problems from epidemiology, ecology, and physiology. All chapters include realistic biological examples, including many exercises related to biological questions. In addition, 25 open-ended research projects are provided, suitable for students. An accompanying Web site contains solutions and a tutorial for the implementation of the computational modeling techniques. Calculations can be done in modern computing languages such as Maple, Mathematica, and MATLAB?.

Systems Biology

Author : Andreas Kremling
Publisher : CRC Press
ISBN 13 : 1466567899
Total Pages : 382 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Systems Biology by : Andreas Kremling

Download or read book Systems Biology written by Andreas Kremling and published by CRC Press. This book was released on 2013-11-12 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drawing on the latest research in the field, Systems Biology: Mathematical Modeling and Model Analysis presents many methods for modeling and analyzing biological systems, in particular cellular systems. It shows how to use predictive mathematical models to acquire and analyze knowledge about cellular systems. It also explores how the models are systematically applied in biotechnology. The first part of the book introduces biological basics, such as metabolism, signaling, gene expression, and control as well as mathematical modeling fundamentals, including deterministic models and thermodynamics. The text also discusses linear regression methods, explains the differences between linear and nonlinear regression, and illustrates how to determine input variables to improve estimation accuracy during experimental design. The second part covers intracellular processes, including enzymatic reactions, polymerization processes, and signal transduction. The author highlights the process–function–behavior sequence in cells and shows how modeling and analysis of signal transduction units play a mediating role between process and function. The third part presents theoretical methods that address the dynamics of subsystems and the behavior near a steady state. It covers techniques for determining different time scales, sensitivity analysis, structural kinetic modeling, and theoretical control engineering aspects, including a method for robust control. It also explores frequent patterns (motifs) in biochemical networks, such as the feed-forward loop in the transcriptional network of E. coli. Moving on to models that describe a large number of individual reactions, the last part looks at how these cellular models are used in biotechnology. The book also explains how graphs can illustrate the link between two components in large networks with several interactions.

Introduction to Mathematical Biology

Author : Ching Shan Chou
Publisher : Springer
ISBN 13 : 3319296388
Total Pages : 172 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Introduction to Mathematical Biology by : Ching Shan Chou

Download or read book Introduction to Mathematical Biology written by Ching Shan Chou and published by Springer. This book was released on 2016-04-27 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is based on a one semester course that the authors have been teaching for several years, and includes two sets of case studies. The first includes chemostat models, predator-prey interaction, competition among species, the spread of infectious diseases, and oscillations arising from bifurcations. In developing these topics, readers will also be introduced to the basic theory of ordinary differential equations, and how to work with MATLAB without having any prior programming experience. The second set of case studies were adapted from recent and current research papers to the level of the students. Topics have been selected based on public health interest. This includes the risk of atherosclerosis associated with high cholesterol levels, cancer and immune interactions, cancer therapy, and tuberculosis. Readers will experience how mathematical models and their numerical simulations can provide explanations that guide biological and biomedical research. Considered to be the undergraduate companion to the more advanced book "Mathematical Modeling of Biological Processes" (A. Friedman, C.-Y. Kao, Springer – 2014), this book is geared towards undergraduate students with little background in mathematics and no biological background.

Mathematical Biology: Modeling and Analysis

Author : Avner Friedman
Publisher : American Mathematical Soc.
ISBN 13 : 1470447150
Total Pages : 100 pages
Book Rating : 4.4/5 (74 download)

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Book Synopsis Mathematical Biology: Modeling and Analysis by : Avner Friedman

Download or read book Mathematical Biology: Modeling and Analysis written by Avner Friedman and published by American Mathematical Soc.. This book was released on 2018-06-14 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fast growing field of mathematical biology addresses biological questions using mathematical models from areas such as dynamical systems, probability, statistics, and discrete mathematics. This book considers models that are described by systems of partial differential equations, and it focuses on modeling, rather than on numerical methods and simulations. The models studied are concerned with population dynamics, cancer, risk of plaque growth associated with high cholesterol, and wound healing. A rich variety of open problems demonstrates the exciting challenges and opportunities for research at the interface of mathematics and biology. This book primarily addresses students and researchers in mathematics who do not necessarily have any background in biology and who may have had little exposure to PDEs.

Methods and Models in Mathematical Biology

Author : Johannes Müller
Publisher : Springer
ISBN 13 : 3642272517
Total Pages : 711 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Methods and Models in Mathematical Biology by : Johannes Müller

Download or read book Methods and Models in Mathematical Biology written by Johannes Müller and published by Springer. This book was released on 2015-08-13 with total page 711 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book developed from classes in mathematical biology taught by the authors over several years at the Technische Universität München. The main themes are modeling principles, mathematical principles for the analysis of these models and model-based analysis of data. The key topics of modern biomathematics are covered: ecology, epidemiology, biochemistry, regulatory networks, neuronal networks and population genetics. A variety of mathematical methods are introduced, ranging from ordinary and partial differential equations to stochastic graph theory and branching processes. A special emphasis is placed on the interplay between stochastic and deterministic models.

Mathematical Models in Biology

Author : Valeria Zazzu
Publisher : Springer
ISBN 13 : 3319234978
Total Pages : 199 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Mathematical Models in Biology by : Valeria Zazzu

Download or read book Mathematical Models in Biology written by Valeria Zazzu and published by Springer. This book was released on 2015-11-26 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents an exciting collection of contributions based on the workshop “Bringing Maths to Life” held October 27-29, 2014 in Naples, Italy. The state-of-the art research in biology and the statistical and analytical challenges facing huge masses of data collection are treated in this Work. Specific topics explored in depth surround the sessions and special invited sessions of the workshop and include genetic variability via differential expression, molecular dynamics and modeling, complex biological systems viewed from quantitative models, and microscopy images processing, to name several. In depth discussions of the mathematical analysis required to extract insights from complex bodies of biological datasets, to aid development in the field novel algorithms, methods and software tools for genetic variability, molecular dynamics, and complex biological systems are presented in this book. Researchers and graduate students in biology, life science, and mathematics/statistics will find the content useful as it addresses existing challenges in identifying the gaps between mathematical modeling and biological research. The shared solutions will aid and promote further collaboration between life sciences and mathematics.

Exploring Mathematical Modeling in Biology Through Case Studies and Experimental Activities

Author : Rebecca Sanft
Publisher : Academic Press
ISBN 13 : 0128195959
Total Pages : 260 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Exploring Mathematical Modeling in Biology Through Case Studies and Experimental Activities by : Rebecca Sanft

Download or read book Exploring Mathematical Modeling in Biology Through Case Studies and Experimental Activities written by Rebecca Sanft and published by Academic Press. This book was released on 2020-04-15 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exploring Mathematical Modeling in Biology through Case Studies and Experimental Activities provides supporting materials for courses taken by students majoring in mathematics, computer science or in the life sciences. The book's cases and lab exercises focus on hypothesis testing and model development in the context of real data. The supporting mathematical, coding and biological background permit readers to explore a problem, understand assumptions, and the meaning of their results. The experiential components provide hands-on learning both in the lab and on the computer. As a beginning text in modeling, readers will learn to value the approach and apply competencies in other settings. Included case studies focus on building a model to solve a particular biological problem from concept and translation into a mathematical form, to validating the parameters, testing the quality of the model and finally interpreting the outcome in biological terms. The book also shows how particular mathematical approaches are adapted to a variety of problems at multiple biological scales. Finally, the labs bring the biological problems and the practical issues of collecting data to actually test the model and/or adapting the mathematics to the data that can be collected. Presents a single volume on mathematics and biological examples, with data and wet lab experiences suitable for non-experts Contains three real-world biological case studies and one wet lab for application of the mathematical models Includes R code templates throughout the text, which are also available through an online repository, along with the necessary data files to complete all projects and labs

Explorations of Mathematical Models in Biology with MATLAB

Author : Mazen Shahin
Publisher : John Wiley & Sons
ISBN 13 : 1118548531
Total Pages : 304 pages
Book Rating : 4.1/5 (185 download)

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Book Synopsis Explorations of Mathematical Models in Biology with MATLAB by : Mazen Shahin

Download or read book Explorations of Mathematical Models in Biology with MATLAB written by Mazen Shahin and published by John Wiley & Sons. This book was released on 2013-12-24 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explore and analyze the solutions of mathematical models from diverse disciplines As biology increasingly depends on data, algorithms, and models, it has become necessary to use a computing language, such as the user-friendly MATLAB, to focus more on building and analyzing models as opposed to configuring tedious calculations. Explorations of Mathematical Models in Biology with MATLAB provides an introduction to model creation using MATLAB, followed by the translation, analysis, interpretation, and observation of the models. With an integrated and interdisciplinary approach that embeds mathematical modeling into biological applications, the book illustrates numerous applications of mathematical techniques within biology, ecology, and environmental sciences. Featuring a quantitative, computational, and mathematical approach, the book includes: Examples of real-world applications, such as population dynamics, genetics, drug administration, interacting species, and the spread of contagious diseases, to showcase the relevancy and wide applicability of abstract mathematical techniques Discussion of various mathematical concepts, such as Markov chains, matrix algebra, eigenvalues, eigenvectors, first-order linear difference equations, and nonlinear first-order difference equations Coverage of difference equations to model a wide range of real-life discrete time situations in diverse areas as well as discussions on matrices to model linear problems Solutions to selected exercises and additional MATLAB codes Explorations of Mathematical Models in Biology with MATLAB is an ideal textbook for upper-undergraduate courses in mathematical models in biology, theoretical ecology, bioeconomics, forensic science, applied mathematics, and environmental science. The book is also an excellent reference for biologists, ecologists, mathematicians, biomathematicians, and environmental and resource economists.

Mathematical Models in Population Biology and Epidemiology

Author : Fred Brauer
Publisher : Springer Science & Business Media
ISBN 13 : 1475735162
Total Pages : 432 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Mathematical Models in Population Biology and Epidemiology by : Fred Brauer

Download or read book Mathematical Models in Population Biology and Epidemiology written by Fred Brauer and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: The goal of this book is to search for a balance between simple and analyzable models and unsolvable models which are capable of addressing important questions on population biology. Part I focusses on single species simple models including those which have been used to predict the growth of human and animal population in the past. Single population models are, in some sense, the building blocks of more realistic models -- the subject of Part II. Their role is fundamental to the study of ecological and demographic processes including the role of population structure and spatial heterogeneity -- the subject of Part III. This book, which will include both examples and exercises, is of use to practitioners, graduate students, and scientists working in the field.

Mathematical Modeling of Biological Systems

Author : Harvey J. Gold
Publisher : John Wiley & Sons
ISBN 13 :
Total Pages : 392 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Mathematical Modeling of Biological Systems by : Harvey J. Gold

Download or read book Mathematical Modeling of Biological Systems written by Harvey J. Gold and published by John Wiley & Sons. This book was released on 1977 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: The modeling process - an overview. Dimension and similarity. Probability models. Dynamic processes. Interacting dynamic processes. Feedback control and stability of biological systems. Curve fiting: estimating the parameters. Computing.