Manual of Stroke Models in Rats

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Author :
Publisher : CRC Press
ISBN 13 : 0203881087
Total Pages : 437 pages
Book Rating : 4.2/5 (38 download)

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Book Synopsis Manual of Stroke Models in Rats by : Yanlin Wang-Fischer

Download or read book Manual of Stroke Models in Rats written by Yanlin Wang-Fischer and published by CRC Press. This book was released on 2008-07-31 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last few years, exciting new insights into mechanisms and treatment of stroke have been obtained from animal experiments. Hence, the use of animal models to induce stroke are of paramount importance as research tools. While a few articles on this topic have been published in select journals, until now there has not been a systematic technical book available which assists researchers in building upon commonly known knowledge. The Manual of Stroke Models in Rats explains in great detail the methods and techniques for accomplishing different stroke models in rats, as well as some techniques using mice. Expert contributors to this text include the most recent research information available, as well as generally recognized facts, making this volume an imperative tool for those researchers seeking to identify new areas of exploration. The first text in 20 years to detail new techniques in rat stroke models The book begins with a statistical update of stroke in America, and proceeds to discuss the rationale for using ischemic stroke models. Major sections include different surgical models of stroke induced by the occlusion of the distal middle cerebral artery, by intraluminal filament or embolic implantation, by photochemically induced thrombosis, global cerebral ischemia induced by asphyxia cardiac arrest or by four-vessel occlusion, and brain hemorrhage. The book also includes anesthesia procedures, general principles of microsurgery, and a study of microsurgical instruments. Numerous tables, figures, and color images are used to supplement the material. The editor, Dr. Yanlin Wang-Fischer, has published more than 40 scientific articles in various medical journals and contributed to several projects related to animal models and surgeries. In this volume, she brings together contributors who represent the cutting edge of research in the field. By reviewing the methods in this detailed technical treatise, researchers will be armed with the latest strategies in preparing their own experimental stroke models.

Rodent Models of Stroke

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Author :
Publisher : Humana
ISBN 13 : 9781493958078
Total Pages : 286 pages
Book Rating : 4.9/5 (58 download)

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Book Synopsis Rodent Models of Stroke by : Ulrich Dirnagl

Download or read book Rodent Models of Stroke written by Ulrich Dirnagl and published by Humana. This book was released on 2016-08-23 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: In view of the numerous failures of clinical trials aimed at improving stroke therapy, the role and potential benefit of experimentally modeling focal cerebral ischemia in rodents has been debated. When methods of systematic review and metaanalyis are applied, however, it turns out that experimental models actually faithfully predicted the negative outcomes of clinical trials. In addition, thrombolysis and neuroprotection by hypothermia, first described in animal models, are key examples of treatment modalities that have made it successfully into clinical practice. In Rodent Models of Stroke, an international consortium of authors aims at critically addressing the issues on a very practical level, from choosing the model and outcome measures, designing the experiment, conducting and analyzing it, to reporting it in a scientific publication. The structure and content of the book reflect both the authors’ longstanding expertise in experimental and clinical stroke research and their roles in training the scientific community in the tools of the trade. As a volume in the successful Neuromethods series, the chapters provide authoritative reviews of the most commonly used, well-honed approaches in the field today. Stimulating and easy-to-use, Rodent Models of Stroke will help its readers understand the limitations and the opportunities of modeling stroke in rodents and enable them to conduct experiments which will not only improve our understanding of the pathophysiology of this devastating disorder but also serve as the basis for developing new highly effective treatments.

Models and Techniques in Stroke Biology

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Author :
Publisher : Springer Nature
ISBN 13 : 9813366796
Total Pages : 115 pages
Book Rating : 4.8/5 (133 download)

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Book Synopsis Models and Techniques in Stroke Biology by : Amit Kumar Tripathi

Download or read book Models and Techniques in Stroke Biology written by Amit Kumar Tripathi and published by Springer Nature. This book was released on 2021-03-30 with total page 115 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes various tools and techniques used to provide insights into the cellular and molecular pathophysiology of stroke. It also presents rodent animal models to help shed light on the pathophysiology of ischemic stroke. Presenting the latest information on the different types of stroke, including embolic, filament, photothrombotic, and bilateral common carotid artery, the book also describes techniques that are used for confirmation of stroke surgery, such as laser speckle imaging (LSI) and laser Doppler flowmetry (LDF), and discusses the non-human primates that are used in stroke surgery, cerebral venous sinuous thrombosis, and neurobehavioral assessment. Lastly, it analyzes various neuroprotective agents to treat and prevent ischemic stroke, and examines the challenges and advances in treating and preventing acute ischemic stroke.

Experimental Surgical Models in the Laboratory Rat

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Author :
Publisher : CRC Press
ISBN 13 : 1420093274
Total Pages : 232 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Experimental Surgical Models in the Laboratory Rat by : Alfredo Rigalli

Download or read book Experimental Surgical Models in the Laboratory Rat written by Alfredo Rigalli and published by CRC Press. This book was released on 2016-04-19 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: An All-Inclusive Guide to Surgical Techniques on RatsThe design of an adequate surgical model, like the choice of the animal model itself, is extremely important for obtaining reliable valuable data. Experimental Surgical Models in the Laboratory Rat summarizes a series of techniques that were applied in the Bone Biology Laboratories, School of Med

Handbook of Exotic Pet Medicine

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Publisher : John Wiley & Sons
ISBN 13 : 111938995X
Total Pages : 524 pages
Book Rating : 4.1/5 (193 download)

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Book Synopsis Handbook of Exotic Pet Medicine by : Marie Kubiak

Download or read book Handbook of Exotic Pet Medicine written by Marie Kubiak and published by John Wiley & Sons. This book was released on 2020-08-24 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: Easy-to-use, comprehensive reference covering the less common species encountered in general veterinary practice Handbook of Exotic Pet Medicine provides easy-to-access, detailed information on a wide variety of exotic species that can be encountered in general veterinary practice. Offering excellent coverage of topics such as basic techniques, preventative health measures, and a formulary for each species, each chapter uses the same easy-to-follow format so that users can find information quickly while working in the clinic. Presented in full colour, with over 400 photographs, the book gives small animal practitioners the confidence to handle and treat more familiar pets such as budgerigars, African grey parrots, bearded dragons, corn snakes, tortoises, pygmy hedgehogs, hamsters and rats. Other species that may be presented less frequently including skunks, marmosets, sugar gliders, koi carp, chameleons and terrapins are also covered in detail to enable clinicians to quickly access relevant information. Provides comprehensive coverage of many exotic pet species that veterinarians may encounter in general practice situations Presents evidence-based discussions of topics including biological parameters, husbandry, clinical evaluation, hospitalization requirements, common medical and surgical conditions, radiographic imaging, and more The Handbook of Exotic Pet Medicine is an ideal one-stop reference for the busy general practitioner seeing the occasional exotic animal, veterinary surgeons with an established exotic animal caseload, veterinary students and veterinary nurses wishing to further their knowledge.

Neuromechanical Property Identification in Spastic Muscles: Perspectives for Instrumented Assessment, Modeling and Intervention Evaluation

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889711404
Total Pages : 143 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Neuromechanical Property Identification in Spastic Muscles: Perspectives for Instrumented Assessment, Modeling and Intervention Evaluation by : Ruoli Wang

Download or read book Neuromechanical Property Identification in Spastic Muscles: Perspectives for Instrumented Assessment, Modeling and Intervention Evaluation written by Ruoli Wang and published by Frontiers Media SA. This book was released on 2021-08-03 with total page 143 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Advances in Brain Imaging Techniques

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Publisher : Springer Nature
ISBN 13 : 9811913528
Total Pages : 265 pages
Book Rating : 4.8/5 (119 download)

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Book Synopsis Advances in Brain Imaging Techniques by : Nirmal Mazumder

Download or read book Advances in Brain Imaging Techniques written by Nirmal Mazumder and published by Springer Nature. This book was released on 2022-05-19 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book reviews the recent developments in brain imaging and their technological advancements to understand molecular mechanisms associated with neurological disorders and basic behaviors in humans and rodents at the structural, molecular, and functional levels. It discusses the usefulness of advanced optical microscopy techniques, including optical coherence tomography (OCT), miniscope, multiphoton fluorescence (2PF & 3PF), adaptive optics, harmonic generation, and Raman microscopy for understanding pathomechanism of brain disorders and pathological and physiological changes associated with neurodegenerative diseases. Also, the book presents conventional imaging modalities, including Magnetic Resonance Imaging (MRI), for delineating underlying mechanisms and precise early diagnosis of neurological disorders. This book is a useful resource for neuroscientists and researchers working in biomedical engineering and optics.

Quantitative Magnetic Resonance Imaging

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Publisher : Academic Press
ISBN 13 : 0128170581
Total Pages : 1094 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Quantitative Magnetic Resonance Imaging by : Nicole Seiberlich

Download or read book Quantitative Magnetic Resonance Imaging written by Nicole Seiberlich and published by Academic Press. This book was released on 2020-11-18 with total page 1094 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantitative Magnetic Resonance Imaging is a ‘go-to’ reference for methods and applications of quantitative magnetic resonance imaging, with specific sections on Relaxometry, Perfusion, and Diffusion. Each section will start with an explanation of the basic techniques for mapping the tissue property in question, including a description of the challenges that arise when using these basic approaches. For properties which can be measured in multiple ways, each of these basic methods will be described in separate chapters. Following the basics, a chapter in each section presents more advanced and recently proposed techniques for quantitative tissue property mapping, with a concluding chapter on clinical applications. The reader will learn: The basic physics behind tissue property mapping How to implement basic pulse sequences for the quantitative measurement of tissue properties The strengths and limitations to the basic and more rapid methods for mapping the magnetic relaxation properties T1, T2, and T2* The pros and cons for different approaches to mapping perfusion The methods of Diffusion-weighted imaging and how this approach can be used to generate diffusion tensor maps and more complex representations of diffusion How flow, magneto-electric tissue property, fat fraction, exchange, elastography, and temperature mapping are performed How fast imaging approaches including parallel imaging, compressed sensing, and Magnetic Resonance Fingerprinting can be used to accelerate or improve tissue property mapping schemes How tissue property mapping is used clinically in different organs Structured to cater for MRI researchers and graduate students with a wide variety of backgrounds Explains basic methods for quantitatively measuring tissue properties with MRI - including T1, T2, perfusion, diffusion, fat and iron fraction, elastography, flow, susceptibility - enabling the implementation of pulse sequences to perform measurements Shows the limitations of the techniques and explains the challenges to the clinical adoption of these traditional methods, presenting the latest research in rapid quantitative imaging which has the possibility to tackle these challenges Each section contains a chapter explaining the basics of novel ideas for quantitative mapping, such as compressed sensing and Magnetic Resonance Fingerprinting-based approaches

Animal Models of Acute Neurological Injuries

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1603271856
Total Pages : 490 pages
Book Rating : 4.6/5 (32 download)

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Book Synopsis Animal Models of Acute Neurological Injuries by : Jun Chen

Download or read book Animal Models of Acute Neurological Injuries written by Jun Chen and published by Springer Science & Business Media. This book was released on 2008-12-16 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite numerous recent studies and exciting discoveries in the field, only limited treatment is available today for the victims of acute neurological injuries. Animal Models of Acute Neurological Injuries provides a standardized methodology manual designed to eliminate the inconsistent preparations and variability that currently jeopardizes advances in the field. Contributed by top experts and many original developers of the models, each chapter contains a step-by-step, proven procedure and visual aids covering the most commonly used animal models of neurological injury in order to highlight the practical applications of animal models rather than the theoretical issues. This intensive volume presents its readily reproducible protocols with great clarity and consistency to best aid neuroscientists and neurobiologists in laboratory testing and experimentation. Comprehensive and cutting-edge, Animal Models of Acute Neurological Injuries is an ideal guide for scientists and researchers who wish to pursue this vital course of study with the proficiency and precision that the field requires.

Atlas of the Neonatal Rat Brain

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Publisher : CRC Press
ISBN 13 : 143984013X
Total Pages : 190 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Atlas of the Neonatal Rat Brain by : Renuka Ramachandra

Download or read book Atlas of the Neonatal Rat Brain written by Renuka Ramachandra and published by CRC Press. This book was released on 2016-04-19 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: Atlas of the Neonatal Rat Brain provides photographic, histological illustrations of the anatomical features of the neonatal rat brain at postnatal (P) days P-1, P-7, and P-14. The sections are Nissl stained with Cresyl violet, creating photomicrographs with high resolution and clarity. The structures are directly labeled on the images, making it e

Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research

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Publisher : National Academies Press
ISBN 13 : 030916785X
Total Pages : 223 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research by : National Research Council

Download or read book Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research written by National Research Council and published by National Academies Press. This book was released on 2003-08-22 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expanding on the National Research Council's Guide for the Care and Use of Laboratory Animals, this book deals specifically with mammals in neuroscience and behavioral research laboratories. It offers flexible guidelines for the care of these animals, and guidance on adapting these guidelines to various situations without hindering the research process. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research offers a more in-depth treatment of concerns specific to these disciplines than any previous guide on animal care and use. It treats on such important subjects as: The important role that the researcher and veterinarian play in developing animal protocols. Methods for assessing and ensuring an animal's well-being. General animal-care elements as they apply to neuroscience and behavioral research, and common animal welfare challenges this research can pose. The use of professional judgment and careful interpretation of regulations and guidelines to develop performance standards ensuring animal well-being and high-quality research. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research treats the development and evaluation of animal-use protocols as a decision-making process, not just a decision. To this end, it presents the most current, in-depth information about the best practices for animal care and use, as they pertain to the intricacies of neuroscience and behavioral research.

Stereotaxic Neurosurgery in Laboratory Rodent

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Publisher : Springer Science & Business
ISBN 13 : 2817804724
Total Pages : 198 pages
Book Rating : 4.8/5 (178 download)

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Book Synopsis Stereotaxic Neurosurgery in Laboratory Rodent by : Barbara Ferry

Download or read book Stereotaxic Neurosurgery in Laboratory Rodent written by Barbara Ferry and published by Springer Science & Business. This book was released on 2014-04-22 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stereotaxic neurosurgery in rodents is used by a variety of people working at research laboratories (research staff, technicians, students at animal facilities...). The present handbook presents all the steps necessary to complete a stereotaxic neurosurgery protocol in accordance with current animal welfare guidelines. This book will guide surgeons step by step, from anesthesia to the post-surgery recovery procedures, including asepsis of the surgical tools and surgical zone, analgesia, correctly identifying the reference points on the skull and brain targets, etc. In keeping with the current international trends, the authors above all focus on the following points: the consideration of pain and how to best treat it depending on the type of surgery; and ensuring asepsis. This book will serve as an important reference work and valuable guidebook for the scientific community.

Encyclopedia of the Neurological Sciences

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Publisher : Academic Press
ISBN 13 : 0123851580
Total Pages : 4744 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Encyclopedia of the Neurological Sciences by :

Download or read book Encyclopedia of the Neurological Sciences written by and published by Academic Press. This book was released on 2014-04-29 with total page 4744 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Encyclopedia of the Neurological Sciences, Second Edition, Four Volume Set develops from the first edition, covering all areas of neurological sciences through over 1000 entries focused on a wide variety of topics in neurology, neurosurgery, psychiatry and other related areas of neuroscience. The contributing authors represent all aspects of neurology from many viewpoints and disciplines to provide a complete overview of the field. Entries are designed to be understandable without detailed background knowledge in the subject matter, and cross-referencing and suggested further reading lead the reader from a basic knowledge of the subject to more advanced understanding. The easy-to-use 'encyclopedic-dictionary' format of the Encyclopedia of the Neurological Sciences, Second Edition features alphabetic entries, extensive cross-referencing, and a thorough index for quick reference. The wealth of information provided by these four volumes makes this reference work a trusted source of valuable information for a wide range of researchers, from undergraduate students to academic researchers. Provides comprehensive coverage of the field of neurological science in over 1,000 entries in 4 volumes "Encyclopedic-dictionary" format provides for concise, readable entries and easy searching Presents complete, up-to-date information on 32 separate areas of neurology Entries are supplemented with extensive cross-referencing, useful references to primary research articles, and an extensive index

Animal Experimentation: Working Towards a Paradigm Change

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Author :
Publisher : BRILL
ISBN 13 : 9004391193
Total Pages : 749 pages
Book Rating : 4.0/5 (43 download)

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Book Synopsis Animal Experimentation: Working Towards a Paradigm Change by : Kathrin Herrmann

Download or read book Animal Experimentation: Working Towards a Paradigm Change written by Kathrin Herrmann and published by BRILL. This book was released on 2019-04-30 with total page 749 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal experimentation has been one of the most controversial areas of animal use, mainly due to the intentional harms inflicted upon animals for the sake of hoped-for benefits in humans. Despite this rationale for continued animal experimentation, shortcomings of this practice have become increasingly more apparent and well-documented. However, these limitations are not yet widely known or appreciated, and there is a danger that they may simply be ignored. The 51 experts who have contributed to Animal Experimentation: Working Towards a Paradigm Change critically review current animal use in science, present new and innovative non-animal approaches to address urgent scientific questions, and offer a roadmap towards an animal-free world of science.

The Laboratory Rat, Second Edition

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Publisher : CRC Press
ISBN 13 : 1439829861
Total Pages : 403 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis The Laboratory Rat, Second Edition by : Patrick Sharp

Download or read book The Laboratory Rat, Second Edition written by Patrick Sharp and published by CRC Press. This book was released on 2012-12-11 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rats have long been recognized as a valuable biomedical research model, notably in the investigation of aging, toxicology, addiction, and common human diseases such as diabetes and hypertension. In many instances, individuals conducting such research studies are charged with important responsibilities, including animal facility management, animal husbandry, veterinary care, regulatory compliance, and various experimental methodologies. With the advent of genetic manipulations and biomedical research technological advances such as bioimaging, the versatility and usefulness of the rat as an animal model has soared. The Laboratory Rat, Second Edition captures the multiple advances in this important animal model’s husbandry, veterinary care, and experimental methodology. This edition features augmented, expanded, and novel information on biology, anesthesia, analgesia, and experimental techniques benefiting personnel working with rats—from the animal care staff to the researcher and everyone in between. The book is also extremely useful to institutional animal care and use program supporters and elements, including animal care and use committees, institutional officials, occupational health and safety professionals, veterinary technicians, and veterinarians.

Brain Repair After Stroke

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Publisher : Cambridge University Press
ISBN 13 : 1139490656
Total Pages : 307 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Brain Repair After Stroke by : Steven C. Cramer

Download or read book Brain Repair After Stroke written by Steven C. Cramer and published by Cambridge University Press. This book was released on 2010-10-28 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Increasing evidence identifies the possibility of restoring function to the damaged brain via exogenous therapies. One major target for these advances is stroke, where most patients can be left with significant disability. Treatments have the potential to improve the victim's quality of life significantly and reduce the time and expense of rehabilitation. Brain Repair After Stroke reviews the biology of spontaneous brain repair after stroke in animal models and in humans. Detailed chapters cover the many forms of therapy being explored to promote brain repair and consider clinical trial issues in this context. This book provides a summary of the neurobiology of innate and treatment-induced repair mechanisms after hypoxia and reviews the state of the art for human therapeutics in relation to promoting behavioral recovery after stroke. Essential reading for stroke physicians, neurologists, rehabilitation physicians and neuropsychologists.

Textbook of Stroke Medicine

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Author :
Publisher : Cambridge University Press
ISBN 13 : 1107047498
Total Pages : 425 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Textbook of Stroke Medicine by : Michael Brainin

Download or read book Textbook of Stroke Medicine written by Michael Brainin and published by Cambridge University Press. This book was released on 2014-09-11 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fully revised throughout, the new edition of this concise textbook is aimed at doctors preparing to specialize in stroke care.