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Mammary Gland Development Methods And Protocols
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Book Synopsis Mammary Gland Development by : Finian Martin
Download or read book Mammary Gland Development written by Finian Martin and published by Humana. This book was released on 2016-10-29 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides key molecular biological protocols and experimental strategies currently employed to study the various stages of mammary gland development. Chapters are divided into four parts covering genetically modified mouse models that exhibit prenatal and pubertal mammary gland phenotypes, 2D and 3D-model culture systems, methodologies for mammary stem cell isolation, and translational applications that provide a bridge between experimental studies of mammary gland development and the study of human breast cancer. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Mammary Gland Development: Methods and Protocols will be useful for researchers whose primary interest is in mammary gland development; developmental biologists, epithelial cell biologists, and those with an interest in molecular mechanisms underlying breast cancer.
Book Synopsis Mammary Stem Cells by : Maria del Mar Vivanco
Download or read book Mammary Stem Cells written by Maria del Mar Vivanco and published by Humana. This book was released on 2015-06-04 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The identification of normal and breast cancer stem cells has offered a new vision of this heterogeneous disease and new hopes for its prognosis and treatment. This volume provides an overview of recent developments in mammary stem cell research and discusses the many varieties of approaches used by researchers to investigate the properties and functions of mammary stem cells. The beginning chapters provide readers with an introduction to mammary stem cells, and the processes used to characterize stem cells and isolate them via fluorescent activated cell sorting. The next few chapters discuss DNA and mRNA sequencing, proteomic techniques to help profile cells, lentiviral cell transduction for gene expression, and in vivo lineage tracing. The final few chapters are dedicated to following stem cells from their initial niche to the new microenvironment at their metastasis site, and to studying these cells using physical and mathematical approaches. Written in the highly successful Methods in Molecular Biology series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory. Authoritative and cutting-edge, Mammary Stem Cells: Methods and Protocols aims to help members of the scientific community explore the behavior of stem cells and how to work with them in order to guide the design of new and complimentary strategies to be applied in the clinic with the ultimate end goal of fighting breast cancer.
Book Synopsis Biology of the Mammary Gland by : John A. Mol
Download or read book Biology of the Mammary Gland written by John A. Mol and published by Springer Science & Business Media. This book was released on 2006-04-11 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the European Cooperation in the Field of Scientific and Technical Research (COST 825) Symposium on Mammary Gland Biology, held September 16-18, 1999, in Tours, France. It is difficult to overstate the evolutionary and functional significance of mammary tissue in biology. Substantial progress has been made by researchers in various disciplines, particularly over the last fifteen years, towards realizing the potential of this tissue to yield powerful experimental models for morphogenesis and tissue development; for cellular differentiation; for the biosynthesis and secretion of proteins, lipids, small molecules and inorganic salts; and for the coordination and regulation of these processes. More recently, the possibility of exploiting the secretory epithelial cells of mammary tissue as `cell factories' has become a reality and the recombinant production by lactating animals of an increasing number of proteins, valuable both in the pharmaceutical and `nutraceutical' fields, is in progress or under development. Also in this sphere of agricultural production, genetic as well as nutritional technologies are under investigation and exploitation to optimize milk composition for various end-uses - for instance in food process and manufacture. The possibilities of deriving health benefit from the bioactive properties of some of the minor constituents of milk are emerging to counter the highly-publicized negative health impact of excessive consumption of saturated animal fats. In human nutrition and medicine, the mammary gland is both a source of nutrition to the neonate and a potential health threat to the adult female - breast cancer remains the major single cause of female mortality in most developed countries. This volume provides a unique glimpse into our understanding, at the cutting edge of a variety of disciplines, of this versatile and extraordinary tissue, at the birth of the twenty-first century.
Book Synopsis Mammary Glands by : Edmund B. Rucker
Download or read book Mammary Glands written by Edmund B. Rucker and published by . This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a compilation of manuscripts that encompass a breadth of information from different species including rodents, dogs, cows, goats, and sheep. Normal developmental processes are covered and anatomical features are discussed, as well as the impact and significance of environmental chemicals and epigenetics on the mammary gland. In terms of disease states, cancer and mastitis are the most impactful in the fields of human medicine and livestock management, respectively, in the context of mammary gland biology. Therefore, this book presents in depth analyses of these diseases over several chapters and different model systems. Rodent and canine cancer models are discussed, which are very relevant in understanding the roles that genes and the environment play in human breast cancer. In the livestock industry, mastitis in the dairy sector has a deep economic impact globally, and results in over a billion dollar loss annually. Several chapters are devoted towards this disease in dairy cattle, sheep and goats, with an underlying theme of generating newer detection strategies to detect infections at an earlier stage. An up-to-date description of the most important signaling pathways and mechanisms that impact both development and disease are included. A gamut of sub-disciplines are found throughout the book that covers the main aspects of anatomy, physiology, cell biology, genetics, and molecular biology in both development and diseases of the mammary gland.
Book Synopsis Methods in Mammary Gland Biology and Breast Cancer Research by : Margot M Ip
Download or read book Methods in Mammary Gland Biology and Breast Cancer Research written by Margot M Ip and published by . This book was released on 2000-12-31 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Mammary Gland by : Margaret C. Neville
Download or read book The Mammary Gland written by Margaret C. Neville and published by Springer. This book was released on 2013-10-09 with total page 625 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Mammary Gland as an Experimental Model by : Mina Bissell
Download or read book The Mammary Gland as an Experimental Model written by Mina Bissell and published by . This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Studies of mammary gland biology are critically important given the prevalence of breast cancer in the population. There are many other reasons to study this organ, however. It represents an excellent model system for research into developmental mechanisms, gene regulation, tissue organization, hormonal action, secretion, and stem cell biology, revealing general principles that can be extended to other organs and tissues. This book provides valuable lessons for all cell, developmental, and cancer biologists.
Download or read book Lactogenesis written by Monica Reynolds and published by University of Pennsylvania Press. This book was released on 2016-11-11 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of a symposium, satellite to the 24th International Congress of Physiological Sciences, University of Pennsylvania.
Book Synopsis Designing Foods by : National Research Council
Download or read book Designing Foods written by National Research Council and published by National Academies Press. This book was released on 1988-02-01 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: This lively book examines recent trends in animal product consumption and diet; reviews industry efforts, policies, and programs aimed at improving the nutritional attributes of animal products; and offers suggestions for further research. In addition, the volume reviews dietary and health recommendations from major health organizations and notes specific target levels for nutrients.
Book Synopsis Diseases of Swine by : Jeffrey J. Zimmerman
Download or read book Diseases of Swine written by Jeffrey J. Zimmerman and published by John Wiley & Sons. This book was released on 2019-06-18 with total page 1136 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a fully revised Eleventh Edition of the definitive reference to swine health and disease Diseases of Swine has been the definitive reference on swine health and disease for over 60 years. This new edition has been completely revised to include the latest information, developments, and research in the field. Now with full color images throughout, this comprehensive and authoritative resource has been redesigned for improved consistency and readability, with a reorganized format for more intuitive access to information. Diseases of Swine covers a wide range of essential topics on swine production, health, and management, with contributions from more than 100 of the foremost international experts in the field. This revised edition makes the information easy to find and includes expanded information on welfare and behavior. A key reference for anyone involved in the swine industry, Diseases of Swine, Eleventh Edition: Presents a thorough revision to the gold-standard reference on pig health and disease Features full color images throughout the book Includes information on the most current advances in the field Provides comprehensive information on swine welfare and behavior Offers a reorganized format to make the information more accessible Written for veterinarians, academicians, students, and individuals and agencies responsible for swine health and public health, Diseases of Swine, Eleventh Edition is an essential guide to swine health. "The 11th edition of Diseases of Swine continues to serve as the gold-standard resource for anything and everything related to swine herd health...this edition does an outstanding job of keeping up with the advanced diagnostic technologies and the latest research on new or emerging diseases and syndromes...there is no other informational resource that comes close to providing the depth or quality of information on the topic of swine diseases as does this book"
Book Synopsis Anti-Inflammatory Cytokine II-10 and Mammary Gland Development by :
Download or read book Anti-Inflammatory Cytokine II-10 and Mammary Gland Development written by and published by . This book was released on 2008 with total page 11 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of the award is to compare mammary glands from wildtype and IL-10 knockout mice at critical stages of development. IL10-knockout mice were imported and maintained in University at Buffalo lab animal specific pathogen-free facility. During the first year of the funding (July 06-July 07), we established protocols in our lab for genotyping, mammary gland whole mount preparation and the preparation of paraffin sections of mammary glands. We then mated IL10+/- male with IL10+/- females to generate 144 experimental female mice with +/+ or -/- genotype (72 each) from 80 litters. After excising and processing the glands at 5 critical stages of mammary gland development as described in the grant, we developed data analysis methods to perform the planned comparison. There were no differences between the wildtype (IL10+/+) and IL10-/- mice at up to age day 55. At age day 80 and 150, IL10-/- mice had less terminal end buds suggesting an alteration in mammary gland development. Part of the results are presented in the 2008 Era of Hope meeting (meeting abstract attached).
Book Synopsis 3D Cell Culture by : Zuzana Sumbalova Koledova
Download or read book 3D Cell Culture written by Zuzana Sumbalova Koledova and published by Springer Nature. This book was released on with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Comparative Oncology by : Alecsandru Ioan Baba
Download or read book Comparative Oncology written by Alecsandru Ioan Baba and published by . This book was released on 2007 with total page 787 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Mammography and Beyond by : National Research Council
Download or read book Mammography and Beyond written by National Research Council and published by National Academies Press. This book was released on 2001-07-23 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each year more than 180,000 new cases of breast cancer are diagnosed in women in the U.S. If cancer is detected when small and local, treatment options are less dangerous, intrusive, and costly-and more likely to lead to a cure. Yet those simple facts belie the complexity of developing and disseminating acceptable techniques for breast cancer diagnosis. Even the most exciting new technologies remain clouded with uncertainty. Mammography and Beyond provides a comprehensive and up-to-date perspective on the state of breast cancer screening and diagnosis and recommends steps for developing the most reliable breast cancer detection methods possible. This book reviews the dramatic expansion of breast cancer awareness and screening, examining the capabilities and limitations of current and emerging technologies for breast cancer detection and their effectiveness at actually reducing deaths. The committee discusses issues including national policy toward breast cancer detection, roles of public and private agencies, problems in determining the success of a technique, availability of detection methods to specific populations of women, women's experience during the detection process, cost-benefit analyses, and more. Examining current practices and specifying research and other needs, Mammography and Beyond will be an indispensable resource to policy makers, public health officials, medical practitioners, researchers, women's health advocates, and concerned women and their families.
Book Synopsis Plastic and Reconstructive Surgery by : Ross Farhadieh
Download or read book Plastic and Reconstructive Surgery written by Ross Farhadieh and published by John Wiley & Sons. This book was released on 2015-06-02 with total page 1218 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plastic and reconstructive surgery continues to evolve as new techniques open up new possibilities for the surgeon. In this groundbreaking textbook, contemporary approaches are explained and demonstrated to allow trainee and experienced surgeons alike to understand and assimilate best practice. Containing over 300 outstanding color figures demonstrating surgical practice, an international cast of leading surgeons show the paths to effective plastic surgery technique and outcomes. They cover all the major bases including: Integument Pediatric Plastic Surgery Head and Neck Reconstruction The Breast Trunk, Lower Limb and Sarcomas Upper Limb and Hand Surgery Aesthetic Surgery Comprehensive in scope, practical in nature, Plastic and Reconstructive Surgery is your one-stop guide to successful surgical management of your patients. "This textbook is aimed at the trainee and young plastic surgeon, but it is extremely comprehensive and sufficiently detailed for any practitioner. The information is succinct, yet complete and up to date. . . . For a single-volume book, the detailed knowledge presented is impressive. . . . I think this is a great book. It is packed with good and up-to-date information, and I think it will be an invaluable resource for trainees but also for all plastic surgeons. The editors are to be congratulated on achieving a very difficult task with such success." —from a review by Peter C. Neligan, MB, in Plastic and Reconstructive Surgery "This is exactly what the editors of Plastic and reconstructive surgery: Approaches and Techniques set out to achieve in producing this excellent textbook. . . . It is truly an international effort at all levels, as the editors, from Australia (Ross D. Farhadieh), the UK (Neil W. Bulstrode) and Canada (Sabrina Cugno), have joined forces to recruit over 130 international contributors and produce a resource of over 1100 pages that provides a well-organized and thorough, yet succinct, text of the essentials of current plastic surgery. . . .Many of the contributors are world-renowned experts; however, there is also a new generation of young rising stars whose contributions are equally good, providing a new, fresh and contemporary feel." —from the Foreword by Julian J. Pribaz, Professor of Surgery, Harvard Medical School "The authors here have concentrated all this useful information into their chapters in a quite outstanding manner. Any plastic surgeon of whatever maturity will find this an excellent purchase which he/she will have no reason to regret." —from a review by Douglas H. Harrison in Journal of Plastic, Reconstructive & Aesthetic Surgery
Book Synopsis Guidebook for the Preparation of HACCP Plans by :
Download or read book Guidebook for the Preparation of HACCP Plans written by and published by . This book was released on 1997 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Breasts: A Natural and Unnatural History by : Florence Williams
Download or read book Breasts: A Natural and Unnatural History written by Florence Williams and published by W. W. Norton & Company. This book was released on 2012-05-07 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: A 2012 New York Times Notable Book A 2013 Los Angeles Times Book Award Winner in the Science & Technology category An engaging narrative about an incredible, life-giving organ and its imperiled modern fate. Did you know that breast milk contains substances similar to cannabis? Or that it’s sold on the Internet for 262 times the price of oil? Feted and fetishized, the breast is an evolutionary masterpiece. But in the modern world, the breast is changing. Breasts are getting bigger, arriving earlier, and attracting newfangled chemicals. Increasingly, the odds are stacked against us in the struggle with breast cancer, even among men. What makes breasts so mercurial—and so vulnerable? In this informative and highly entertaining account, intrepid science reporter Florence Williams sets out to uncover the latest scientific findings from the fields of anthropology, biology, and medicine. Her investigation follows the life cycle of the breast from puberty to pregnancy to menopause, taking her from a plastic surgeon’s office where she learns about the importance of cup size in Texas to the laboratory where she discovers the presence of environmental toxins in her own breast milk. The result is a fascinating exploration of where breasts came from, where they have ended up, and what we can do to save them.
