Mammalian Cell Cytotoxicity and Genotoxicity of Disinfection By-products

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Publisher : American Water Works Association
ISBN 13 : 9781605730523
Total Pages : 134 pages
Book Rating : 4.7/5 (35 download)

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Book Synopsis Mammalian Cell Cytotoxicity and Genotoxicity of Disinfection By-products by :

Download or read book Mammalian Cell Cytotoxicity and Genotoxicity of Disinfection By-products written by and published by American Water Works Association. This book was released on 2009 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: This project represents basic research to generate quantitative, comparative in vitro mammalian cell toxicity data of emerging DBPs and related compounds. It is the first systematic cytotoxicity and genotoxicity analysis of its kind --

Comparative Cytotoxicity and Genotoxicity of Drinking Water Disinfection By-products

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Author :
Publisher :
ISBN 13 :
Total Pages : 366 pages
Book Rating : 4.:/5 (517 download)

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Book Synopsis Comparative Cytotoxicity and Genotoxicity of Drinking Water Disinfection By-products by : Yahya Kargalioglu

Download or read book Comparative Cytotoxicity and Genotoxicity of Drinking Water Disinfection By-products written by Yahya Kargalioglu and published by . This book was released on 2001 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Quantitative, Comparative Toxicity and Toxicogenomic Analyses of Nitrogenous Drinking Water Disinfection By-Products

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (931 download)

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Book Synopsis Quantitative, Comparative Toxicity and Toxicogenomic Analyses of Nitrogenous Drinking Water Disinfection By-Products by :

Download or read book Quantitative, Comparative Toxicity and Toxicogenomic Analyses of Nitrogenous Drinking Water Disinfection By-Products written by and published by . This book was released on 2008 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Comparative Cytotoxicity, Genotoxicity, and DNA Repair Kinetics of Drinking Water Disinfection By-products

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Publisher :
ISBN 13 :
Total Pages : 134 pages
Book Rating : 4.:/5 (429 download)

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Book Synopsis Comparative Cytotoxicity, Genotoxicity, and DNA Repair Kinetics of Drinking Water Disinfection By-products by : Justin A. Pals

Download or read book Comparative Cytotoxicity, Genotoxicity, and DNA Repair Kinetics of Drinking Water Disinfection By-products written by Justin A. Pals and published by . This book was released on 2009 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Disinfection By-products in Drinking Water

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Author :
Publisher : Academic
ISBN 13 :
Total Pages : 434 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Disinfection By-products in Drinking Water by : Tanju Karanfil

Download or read book Disinfection By-products in Drinking Water written by Tanju Karanfil and published by Academic. This book was released on 2008 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a collection of chapters on the latest international research findings, including emerging issues and state-of-the-art studies, related to disinfection by-product formation and control in drinking waters and treated wastewaters.

Comparative Genotoxicity Assessment of DBPs in Drinking Water

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Author :
Publisher : Amer Water Works Assn
ISBN 13 : 9781583212592
Total Pages : 83 pages
Book Rating : 4.2/5 (125 download)

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Book Synopsis Comparative Genotoxicity Assessment of DBPs in Drinking Water by : R. A. Minear

Download or read book Comparative Genotoxicity Assessment of DBPs in Drinking Water written by R. A. Minear and published by Amer Water Works Assn. This book was released on 2003 with total page 83 pages. Available in PDF, EPUB and Kindle. Book excerpt: This research resulted in a quantitative analysis of the relative cytotoxicity and genotoxicity of the chlorinated and brominated disinfection by-products (DBPs) as well as DBP mixtures isolated from the disinfection of a well-characterized natural organic matter. A principal component of this study was the development of novel microplate-based cytotoxicity and genotoxicity methods for "Salmonella typhimurium" and mammalian cell assay systems. These assays allowed the analytical biology to be integrated with the analytical chemistry portion of this work -- foreword.

Iodinated X-ray Contrast Media (ICM) as Precursors to Disinfection Byproduct (DBP) Formation and Enhanced Toxicity as a Function of PH and Chlorinated Oxidant

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Publisher :
ISBN 13 :
Total Pages : 178 pages
Book Rating : 4.:/5 (128 download)

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Book Synopsis Iodinated X-ray Contrast Media (ICM) as Precursors to Disinfection Byproduct (DBP) Formation and Enhanced Toxicity as a Function of PH and Chlorinated Oxidant by : Alexis Helen Killinger

Download or read book Iodinated X-ray Contrast Media (ICM) as Precursors to Disinfection Byproduct (DBP) Formation and Enhanced Toxicity as a Function of PH and Chlorinated Oxidant written by Alexis Helen Killinger and published by . This book was released on 2016 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: The objective of this study was to investigate the formation of iodinated disinfection by-products (iodo-DBPs) and mammalian cell cyto/genotoxicity in the presence of iodinated x-ray contrast media (ICM), chlorinated oxidants, and natural organic matter (NOM). The ICM chosen as the source of iodide for these experiments were iopamidol and iohexol. The experiments were conducted with aqueous chlorine or monochloramine as the chlorinated oxidant. The experiments were conducted at pH 6.5 - 9.0. The NOM concentration was constant [DOC] = 5.57 mg/L. Chloroform formation in the presence of iopamidol, a regulated DBP, was highest at pH 9.0 with aqueous chlorine (up to 4014 nM) and pH 6.5 with monochloramine (up to 56 nM). Additionally, dichloroiodomethane followed a similar trend in the presence of iopamidol with concentrations in the chlorine experiments forming up to 650 nM and the monochloramine experiments forming up to 52 nM. Trichloroacetic acid (TCAA) formation generally decreased as pH increased; however, iopamidol significantly contributes to TCAA formation at pH 7.5 disrupting the normally observed TCAA formation trend in the presence of NOM. Toxicity of the iopamidol transformation in the presence of chlorinated oxidants and NOM was also investigated. The cytotoxicity index (CTI) values were highest for chlorine (i.e., 21.0) and monochloramine (i.e., 16.5) when compared to control experiments without iopamidol. Genotoxicity index (GTI) values were highest for chlorine (i.e., 7.1) and monochloramine (i.e., 3.5) when compared to control experiments. Iohexol DBP experiments resulted in an enhanced formation of chloroform, while very little dichloroiodomethane formed, and the TCAA formation observed was comparable to the chlorinated source water controls. With iohexol as the iodide source, the CTI and GIT values were highest with aqueous chlorine at 21.6 and 3.8, respectively, when compared to control experiments without iohexol present. Iopamidol acts as a precursor to DBP formation, while also enhancing mammalian cell cytotoxicity and genotoxicity after chlorine or chloramine disinfection. While iohexol formed regulated and unregulated DBPs, it also enhanced mammalian cell cytotoxicity and genotoxicity, though to a lesser extent than iopamidol.

Disinfection By-products in Drinking Water

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Author :
Publisher : Royal Society of Chemistry
ISBN 13 : 1782622713
Total Pages : 368 pages
Book Rating : 4.7/5 (826 download)

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Book Synopsis Disinfection By-products in Drinking Water by : K Clive Thompson

Download or read book Disinfection By-products in Drinking Water written by K Clive Thompson and published by Royal Society of Chemistry. This book was released on 2015-09-29 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering the latest developments in themes related to water disinfection by-products, this book brings the reader right up to date. Stemming from an international conference, contributions are from decision-makers, regulators and the relevant scientific community. Coverage includes emerging disinfection by-products, water treatment, water recycling, monitoring, regulation and health and toxicology aspects. It will be of interest to water companies, public health professionals, drinking water quality regulators, suppliers of laboratory and on-line monitoring equipment, analytical chemists, and academic and industry researchers working in the area of disinfection by-products.

Some Drinking-water Disinfectants and Contaminants, Including Arsenic

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Publisher : IARC
ISBN 13 : 9789283212843
Total Pages : 540 pages
Book Rating : 4.2/5 (128 download)

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Book Synopsis Some Drinking-water Disinfectants and Contaminants, Including Arsenic by : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans

Download or read book Some Drinking-water Disinfectants and Contaminants, Including Arsenic written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by IARC. This book was released on 2004 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: A working group of 23 experts from 13 countries met in Lyon to evaluate the evidence for carcinogenicity of arsenic (mostly naturally occurring) as a contaminant of drinking-water, and of the water-disinfectant chloramine. The working group also evaluated or re-evaluated four chlorination by-products found in drinking-water, namely chloral hydrate, di- and trichloroacetic acids, and 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (also known as MX). High-level exposure to arsenic in drinking-water occurs in some regions such as China, Latin America, Bangladesh and West Bengal. The Working Group reviewed epidemiological studies of human cancer (mainly ecological studies in Taiwan and Chile, and several case-control and cohort studies) in relation to arsenic in drinking-water. Arsenic in drinking-water (primarily inorganic, as arsenate and to a lesser extent arsenite) was evaluated as carcinogenic to humans (Group 1) on the basis of sufficient evidence for an increased risk for cancer of the urinary bladder, lung and skin. Studies on inorganic arsenic in experimental animals provided limited evidence for its carcinogenicity, but sufficient evidence was found in experimental animals for the carcinogenicity of dimethylarsinic acid (an organic form of arsenic), which produced urinary bladder tumours in rats and lung tumours in mice after oral administration.

Disinfection By-products in Drinking Water

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Author :
Publisher : Royal Society of Chemistry
ISBN 13 : 1782620885
Total Pages : 368 pages
Book Rating : 4.7/5 (826 download)

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Book Synopsis Disinfection By-products in Drinking Water by : K. Clive Thompson

Download or read book Disinfection By-products in Drinking Water written by K. Clive Thompson and published by Royal Society of Chemistry. This book was released on 2016 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering the latest developments in themes related to water disinfection by-products, this book brings the academic and industry researchers right up to date.

Toxic Effects on Model Mammalian Cells by Monohalogenated Disinfection Byproducts: Haloacetic Acids and Haloacetonitriles

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (932 download)

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Book Synopsis Toxic Effects on Model Mammalian Cells by Monohalogenated Disinfection Byproducts: Haloacetic Acids and Haloacetonitriles by :

Download or read book Toxic Effects on Model Mammalian Cells by Monohalogenated Disinfection Byproducts: Haloacetic Acids and Haloacetonitriles written by and published by . This book was released on 2013 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Disinfection By-products in Drinking Water

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Author :
Publisher : Butterworth-Heinemann
ISBN 13 : 0081029780
Total Pages : 492 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Disinfection By-products in Drinking Water by : M.N.V. Prasad

Download or read book Disinfection By-products in Drinking Water written by M.N.V. Prasad and published by Butterworth-Heinemann. This book was released on 2020-02-18 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: Disinfection Byproducts in Drinking Water: Detection and Treatment presents cutting-edge research on how to understand the procedures, processes and considerations for detecting and treating disinfection by-products from drinking water, swimming pool water, and wastewater. The book begins with an overview of the different groups of Disinfection Byproducts (DBPs), such as: Trihalomethanes (THM), Halo acetic acids, and Haloacetonitrile (HAN). This coverage is quickly followed by a clear and rigorous exposition of the latest methods and technologies for the characterization, occurrence, formation, transformation and removal of DBPs in drinking water. Other chapters focus on ultraviolet-visible spectroscopy, electron spin resonance, and gas chromatography-mass spectrometry. Researchers will find a valuable resource to a breath of topics for DBP detection and treatment, including various recent techniques, such as microfiltration, nanofiltration membrane and nanotechnology. - Explains the latest research in detection, treatment processes and remediation technologies - Includes sampling, analytical and characterization methods and approaches - Covers cutting-edge research, including membrane based technologies, nanotechnology treatment technologies and bioremediation treatment technologies - Provides background information regarding contamination sources

Disinfection By-Products and Human Health

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Publisher : IWA Publishing
ISBN 13 : 1843395193
Total Pages : 327 pages
Book Rating : 4.8/5 (433 download)

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Book Synopsis Disinfection By-Products and Human Health by : Steve E. Hrudey

Download or read book Disinfection By-Products and Human Health written by Steve E. Hrudey and published by IWA Publishing. This book was released on 2012-04-30 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: Disinfection By-Products and Human Health is based on contributions from speakers who participated in May 2011 workshops on Disinfection By-Products (DBPs) and Human Health at Ozwater 11 in Adelaide, Australia or at an AWA sponsored workshop at the Curtin Water Quality Research Centre, Perth, Australia. The contributions are prepared to facilitate communication with practitioners, rather than researchers, making use of overview illustrations rather than dense text or data tables. Each chapter concludes with up to 5 key findings that are take-home messages for practitioners. Disinfection By-Products and Human Health is aimed specifically at drinking water professionals (engineers, chemists and public health professionals) working on the front lines of drinking water issues where they must encounter actual day-to-day issues of risk management concerning DBPs in relation to all the other regulatory and water quality issues they must manage. Although a topic this complex is certainly not amenable to simplistic explanations, this book aims to provide drinking water professionals with a pragmatic assessment of the current evidence and emerging issues concerning DBPs and public health. Disinfection By-Products and Human Health is an essential, practical and accessible guide for drinking water professionals, engineers, chemists and public health professionals. Editors: Steve E. Hrudey, Professor Emeritus, Analytical & Environmental Toxicology, University of Alberta, Canada, Jeffrey W.A. Charrois, Director and Associate Professor, Curtin Water Quality Research Centre, Curtin University of Technology, Australia, Steve Hrudey is professor emeritus in analytical and environmental toxicology in the University of Alberta's Faculty of Medicine & Dentistry. He spent 13 years as a cabinet-appointed member of the Alberta Environmental Appeals Board, the last four as chair, and was the first non-lawyer to hold this position. During this period, he served on 36 public hearing panels, 19 as chair of the panel. In addition he has testified before senate committees in Canada and the Legislative Council in Western Australia. Hrudey has served on a number of high-profile expert panels, including the Research Advisory Panel to the Walkerton Inquiry (2000-2002), the Expert Panel on Safe Drinking Water for First Nations (2006), the Technical Advisory Committee to the B.C. Minister of Health on turbidity and microbial risk in drinking water (2007-2008, as chair), the Expert Advisory Panel on Water Quality for Washington, D.C., to the U.S. Army Corps of Engineers (2009-2011) and chair of the Royal Society of Canada Expert Panel on Environmental and Health Impacts of Canada's Oil Sands Industry (2009-2010). He has also co-authored or edited nine books, including the widely acclaimed book inspired by the Walkerton tragedy: Safe Drinking Water - Lessons from Recent Outbreaks in Affluent Nations (IWA Publishing, 2004). He has written 26 book chapters, 19 expert panel reports, 163 refereed journal articles, 15 science discussions, six media op-eds and 73 conference proceeding papers. Hrudey is the 2012 winner of the American Water Works Association A.P. Black Research Award for contributions to water science and water supply. This book is sponsored by Australian Water Association (AWA)

Some Chemicals Present in Industrial and Consumer Products, Food and Drinking-water

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Author :
Publisher : IARC Monographs on the Evaluat
ISBN 13 : 9789283213246
Total Pages : 0 pages
Book Rating : 4.2/5 (132 download)

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Book Synopsis Some Chemicals Present in Industrial and Consumer Products, Food and Drinking-water by : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans

Download or read book Some Chemicals Present in Industrial and Consumer Products, Food and Drinking-water written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by IARC Monographs on the Evaluat. This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of the IARC Monographs provides an assessment of the carcinogenicity of 18 chemicals present in industrial and consumer products or food (natural constituents, contaminants, or flavorings) or occurring as water-chlorination by-products. The compounds evaluated include the widely used plasticizer di(2-ethylhexyl) phthalate and the food contaminant 4-methylimidazole. In view of the limited agent-specific information available from epidemiological studies, the IARC Monographs Working Group relied mainly on carcinogenicity bioassays, and mechanistic and other relevant data to evaluate the carcinogenic hazards to humans exposed to these agents.

Analysis and Formation of Disinfection Byproducts in Drinking Water

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Author :
Publisher : Elsevier
ISBN 13 : 0444643443
Total Pages : 180 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Analysis and Formation of Disinfection Byproducts in Drinking Water by :

Download or read book Analysis and Formation of Disinfection Byproducts in Drinking Water written by and published by Elsevier. This book was released on 2021-04-01 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drinking water disinfection has markedly reduced diseases causes by waterborne pathogenic microorganisms. However, an unintended consequence of disinfection and/or oxidation processes is the generation of disinfection byproducts (DBPs) which are formed from the reactions of disinfectants/oxidants with water matrix components. This volume of the Comprehensive Analytical Chemistry Handbook presents recent advances about the formation, identification, and quantification of inorganic and organic DBPs during oxidative processes. The book begins with a first chapter reviewing the most recent non-targeted screening approaches and workflows to characterize DBPs using low-, high-, and ultra-high-resolution mass spectrometry. The second chapter discusses the analysis of inorganic chloramines in waters using on-site and/or in-lab analytical methods. The third chapter provides an overview of the current knowledge about the mechanisms of chlorine dioxide reactions and byproducts formation. The fourth chapter presents some fundamental and practical aspects about ozonation processes in water treatment and provides an overview about ozone reaction mechanisms and byproducts formation. The fifth chapter focuses on the reactivity of halide ions, particularly bromide and iodide, with common oxidants and the role they play in determining the speciation of DBPs in treated waters. The chapter also presents strategies to mitigate the formation of DBPs during oxidation processes. Finally, the last chapter tackles the topic of DBPs formation during potable water reuse. It discusses the formation of DBPs of major concern in both memebrane-based and non-membrane-based potable water reuse treatment schemes.Researchers, water treatment specialists, and regulators will find in this book a valuable and compact resource on several key topics regarding the formation, identification, quantification, and mitigation of DBPs. - Identification and quantification of known and unknown DBPs - Formation of DBPs during different disinfection/oxidation processes - DBPs of concern in new technologies and/or new applications of existing technologies in water treatment

Encyclopedia of Environmental Health

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Author :
Publisher : Elsevier
ISBN 13 : 0444639527
Total Pages : 4896 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Encyclopedia of Environmental Health by :

Download or read book Encyclopedia of Environmental Health written by and published by Elsevier. This book was released on 2019-08-22 with total page 4896 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedia of Environmental Health, Second Edition, Six Volume Set presents the newest release in this fundamental reference that updates and broadens the umbrella of environmental health, especially social and environmental health for its readers. There is ongoing revolution in governance, policies and intervention strategies aimed at evolving changes in health disparities, disease burden, trans-boundary transport and health hazards. This new edition reflects these realities, mapping new directions in the field that include how to minimize threats and develop new scientific paradigms that address emerging local, national and global environmental concerns. Represents a one-stop resource for scientifically reliable information on environmental health Fills a critical gap, with information on one of the most rapidly growing scientific fields of our time Provides comparative approaches to environmental health practice and research in different countries and regions of the world Covers issues behind specific questions and describes the best available scientific methods for environmental risk assessment

Bioanalytical Tools in Water Quality Assessment

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Publisher : IWA Publishing
ISBN 13 : 1843393689
Total Pages : 273 pages
Book Rating : 4.8/5 (433 download)

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Book Synopsis Bioanalytical Tools in Water Quality Assessment by : Beate Escher

Download or read book Bioanalytical Tools in Water Quality Assessment written by Beate Escher and published by IWA Publishing. This book was released on 2011-12-15 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part of Water Quality Set - Buy all four books and save over 30% on buying separately! Bioanalytical Tools in Water Quality Assessment reviews the application of bioanalytical tools to the assessment of water quality including surveillance monitoring. The types of water included range from wastewater to drinking water, including recycled water, as well as treatment processes and advanced water treatment. Bioanalytical Tools in Water Quality Assessment not only demonstrates applications but also fills in the background knowledge in toxicology/ecotoxicology needed to appreciate these applications. Each chapter summarises fundamental material in a targeted way so that information can be applied to better understand the use of bioanalytical tools in water quality assessment. Bioanalytical tools in Water Quality Assessment can be used by lecturers teaching academic and professional courses and also by risk assessors, regulators, experts, consultants, researchers and managers working in the water sector. It can also be a reference manual for environmental engineers, analytical chemists, and toxicologists. Authors: Beate Escher, National Research Centre for Environmental Toxicology (EnTox), The University of Queensland, Australia, Frederic Leusch, Smart Water Research Facility (G51), Griffith University Gold Coast Campus, Australia. With contributions by Heather Chapman and Anita Poulsen