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Lysosomes A Survey
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Download or read book Lysosomes written by Eric Holtzman and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1976 I wrote a monograph on lysosomes (Lysosomes: A Survey, Springer Verlag, Vienna) that was intended as an up-to-date, comprehensive survey. Whatever success I may have achieved then in fulfilling that intention, even the effort now would be foolhardy. The literature has grown so rapidly in the past decade that I certainly could not even read all of the essential papers, let alone understand and analyze them. My goal here, therefore, is simply to introduce the major features of lysosomes at a level I hope will be useful both to I;ldvanced students and to researchers interested in obtaining a broad background. This is in keeping with the design of the Cellular Organelles series: the series is more a set of advanced texts than of review monographs. This design carries with it the decision not to support each point by refer ences to the original literature. I apologize for the injustice involved in such a decision but feel that in any event it would be impossibly unwieldy to cite, adequately and in a balanced manner, the contributions of the vast network of researchers responsible for the information upon which I draw.
Download or read book Fabry Disease written by Deborah Elstein and published by Springer Science & Business Media. This book was released on 2010-08-02 with total page 525 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fabry disease is an X-linked inborn error of metabolism wherein deficiency of a lysosomal enzyme results in systemic deposition of glycosphingolipids. Storage deposition, and hence pathological disease, occurs preferentially in renal glomerular and tubular epithelial cells, myocardial cells, heart valve fibrocytes, neurons of dorsal root ganglia, and in endothelial smooth muscle cells of blood vessels. Thus, Fabry disease is a multi-system disorder, albeit with considerable phenotypic heterogeneity in onset and in severity; however, it is progressive, exhibits extensive morbidity, and is life-threatening. Within the past two decades, there has been a radical change in the natural course Fabry disease by virtue of the availability of specific enzyme replacement therapy. Moreover, there has been a concerted effort to better understand the underlying pathology and equally to identify patients prior to the onset of irreversible end-organ damage. It is to be hoped that the future for patients with Fabry disease can be viewed with greater, albeit guarded, optimism. This state-of-the-art textbook attempts to bridge the span of pre-clinical studies, clinical finding, and management options in a readable but comprehensive manner for the medical practitioner as well as the interested non-medical reader.
Book Synopsis Lysosomes by : Frederick R. Maxfield
Download or read book Lysosomes written by Frederick R. Maxfield and published by John Wiley & Sons. This book was released on 2016-06-22 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discussing recent findings, up-to-date research, and novel strategies, the book integrates perspectives from pharmacology, toxicology, and biochemistry to illustrate the potential of lysosomes in drug discovery and development. • Explores basic principles and properties of lysosomes that allow them to act as regulators of cell metabolism, therapeutic targets, and sites for activation of drug conjugates • Discusses the role of lysosomes in metabolism, drug targeting, apoptosis, cancer, aging, inflammation, autophagy, metabolism, toxicity, and membrane repair • Introduces new pathways in therapeutic development and new mechanisms in drug development
Book Synopsis Anatomy and Physiology by : J. Gordon Betts
Download or read book Anatomy and Physiology written by J. Gordon Betts and published by . This book was released on 2013-04-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Cells, Tissues, and Disease by : Guido Majno
Download or read book Cells, Tissues, and Disease written by Guido Majno and published by Oxford University Press. This book was released on 2004-08-26 with total page 1037 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book lays out the principles of general pathology for biomedical researchers, grad students, medical students, and physicians, with elegance and deep insight. Disease processes are explained in the light of malfunctions at the cellular level, offering a rich understanding of the clinical correlates of all aspects of fundamental cellular physiology and basic biomedicine. The book has been fully revised and updated to present a current but deep understanding of disease states at the cell and tissue levels - cellular pathology, inflammation, immunopathology vascular disturbance, and tumor biology.
Book Synopsis National Institute of Dental Research Programs by : National Institute of Dental Research (U.S.)
Download or read book National Institute of Dental Research Programs written by National Institute of Dental Research (U.S.) and published by . This book was released on with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Dental Research in the United States, Canada, and Great Britain by : National Institute of Dental Research (U.S.)
Download or read book Dental Research in the United States, Canada, and Great Britain written by National Institute of Dental Research (U.S.) and published by . This book was released on 1971 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Dental Research in the United States and Other Countries by :
Download or read book Dental Research in the United States and Other Countries written by and published by . This book was released on 1972 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: A catalog of dental research projects sponsored by federal and non-federal organizations.
Download or read book DHEW Publication written by and published by . This book was released on 1971 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Research Awards Index written by and published by . This book was released on with total page 1128 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Research Grants Index by : National Institutes of Health (U.S.). Division of Research Grants
Download or read book Research Grants Index written by National Institutes of Health (U.S.). Division of Research Grants and published by . This book was released on 1965 with total page 1126 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Acta Morphologica Academiae Scientiarum Hungaricae by :
Download or read book Acta Morphologica Academiae Scientiarum Hungaricae written by and published by . This book was released on 1977 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :University of Michigan. Mental Health Research Institute Publisher :UM Libraries ISBN 13 : Total Pages :644 pages Book Rating :4.3/5 (91 download)
Book Synopsis Mental Health Research Institute Staff Publications by : University of Michigan. Mental Health Research Institute
Download or read book Mental Health Research Institute Staff Publications written by University of Michigan. Mental Health Research Institute and published by UM Libraries. This book was released on 1971 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Genetic and Biochemical Studies on the Expression of Lysosomal Enzymes in Cultured Human Fibroblasts by : Phillip Gerrit de Groot
Download or read book Genetic and Biochemical Studies on the Expression of Lysosomal Enzymes in Cultured Human Fibroblasts written by Phillip Gerrit de Groot and published by . This book was released on 1982 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Cytoplasmic Vesicles—Advances in Research and Application: 2012 Edition by :
Download or read book Cytoplasmic Vesicles—Advances in Research and Application: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cytoplasmic Vesicles—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Cytoplasmic Vesicles. The editors have built Cytoplasmic Vesicles—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Cytoplasmic Vesicles in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Cytoplasmic Vesicles—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1968 with total page 1712 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Biomedical Index to PHS-supported Research by :
Download or read book Biomedical Index to PHS-supported Research written by and published by . This book was released on 1995 with total page 1216 pages. Available in PDF, EPUB and Kindle. Book excerpt:
