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Low Level Radiation And Immune System Damage
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Book Synopsis Low-Level Radiation and Immune System Damage by : Joseph J. Mangano
Download or read book Low-Level Radiation and Immune System Damage written by Joseph J. Mangano and published by CRC Press. This book was released on 2018-01-31 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: Atomic weapons and nuclear power plants: they promised to ensure world peace and provide efficient energy to Americans during the 1940s and 1950s. Meanwhile, the post war prosperity led to the most dramatic population explosion ever witnessed in the United States: the "baby boomer" generation.Times and politics may change, but many baby boomers-as well as their descendants-now live with an unforeseen result of the nuclear age. Rates of immune-related diseases have risen steadily throughout the past few decades, from allergies to cancer. While advances in medical care have kept death rates relatively low, the increased prevalence of certain diseases cannot be ignored.Low Level Radiation and Immune System Damage: An Atomic Era Legacy establishes an undeniable connection between the nuclear build up of the past and the widespread health problems seen today. While baby boomers were growing up in the 40s and 50s, above-ground atomic bomb tests and start ups of civilian nuclear power plants were carried out without fear of public exposure to radioactive emissions.Although the consequences of low-level radiation are still hotly debated, Mangano's research findings emphasize a direct link between nuclear exposure and immune system deficiency. In addition to substantial data on immune disease trends among Americans born between the mid-1940s and mid-1960s, Mangano also examines similar issues concerning baby boomer children and grandchildren. Health professionals, environmentalists, historians and students alike will find much to learn from these pages.As America and the world come to terms with the post-Cold War era, there are still many lessons to recognize, consider, and learn from the still-recent past. Low Level Radiation and Immune System Damage: An Atomic Era Legacy explores a relentless trend that will not soon be over-with potential repercussions into the 21st century.
Book Synopsis Radiation and the Immune System: Current Knowledge and Future Perspectives by : Katalin Lumniczky
Download or read book Radiation and the Immune System: Current Knowledge and Future Perspectives written by Katalin Lumniczky and published by Frontiers Media SA. This book was released on 2018-05-03 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: For long, high dose ionizing radiation was considered as a net immune suppressing agent, as shown, among others, by the exquisite radiosensitivity of the lymphoid system to radiation-induced cell killing. However, recent advances in radiobiology and immunology have made this picture more complex. For example, the recognition that radiation-induced bystander effects, share common mediators with various immunological signalling processes, suggests that they are at least partly immune mediated. Another milestone was the finding, in the field of onco-immunology, that local tumor irradiation can modulate the immunogenicity of tumor cells and the anti-tumor immune responsiveness both locally, in the tumor microenvironment, and at systemic level. These observations paved the way for studies exploring optimal combinations of radiotherapy and immunotherapy in order to achieve a synergistic effect to eradicate tumors. However, not all interactions between radiation and the immune system are beneficial, as it was recognized that many of radiation-induced late side effects are also of immune and inflammatory nature. Currently perhaps the most studied field of research in radiation biology is focused around the biological effects of low doses, where many of the observed pathophysiological endpoints are due to mechanisms other than direct radiation-induced cell killing and are immune-related. Finally, it must not be forgotten that the interactions between the ionizing radiations and the immune system are bi-directional, and activation of the immune system also influences the outcome of radiation exposure. This Research Topic brings together 23 articles and aims to give an overview of the complex and very often contradictory nature of the interactions between ionizing radiation and the immune system. Due to its increasing penetrance in the population both through medical diagnostic or environmental sources or during cosmic travel low dose ionizing radiation exposure is becoming a major epidemiological concern world-wide. Several of the articles within the Research Topic specifically address potential long-term health consequences and the underlying mechanisms of low dose radiation exposure. A major intention of the Editors was also to draw the attention of the non-radiobiological scientific community on the fact that ionizing radiation is by far more than purely an immune suppressing agent.
Book Synopsis Low-Level Radiation and Immune System Damage by : Joseph J. Mangano
Download or read book Low-Level Radiation and Immune System Damage written by Joseph J. Mangano and published by CRC Press. This book was released on 2018-01-31 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Atomic weapons and nuclear power plants: they promised to ensure world peace and provide efficient energy to Americans during the 1940s and 1950s. Meanwhile, the post war prosperity led to the most dramatic population explosion ever witnessed in the United States: the "baby boomer" generation.Times and politics may change, but many baby boomers-as well as their descendants-now live with an unforeseen result of the nuclear age. Rates of immune-related diseases have risen steadily throughout the past few decades, from allergies to cancer. While advances in medical care have kept death rates relatively low, the increased prevalence of certain diseases cannot be ignored.Low Level Radiation and Immune System Damage: An Atomic Era Legacy establishes an undeniable connection between the nuclear build up of the past and the widespread health problems seen today. While baby boomers were growing up in the 40s and 50s, above-ground atomic bomb tests and start ups of civilian nuclear power plants were carried out without fear of public exposure to radioactive emissions.Although the consequences of low-level radiation are still hotly debated, Mangano's research findings emphasize a direct link between nuclear exposure and immune system deficiency. In addition to substantial data on immune disease trends among Americans born between the mid-1940s and mid-1960s, Mangano also examines similar issues concerning baby boomer children and grandchildren. Health professionals, environmentalists, historians and students alike will find much to learn from these pages.As America and the world come to terms with the post-Cold War era, there are still many lessons to recognize, consider, and learn from the still-recent past. Low Level Radiation and Immune System Damage: An Atomic Era Legacy explores a relentless trend that will not soon be over-with potential repercussions into the 21st century.
Book Synopsis Problems in Assessing the Cancer Risks of Low-level Ionizing Radiation Exposure by : United States. General Accounting Office
Download or read book Problems in Assessing the Cancer Risks of Low-level Ionizing Radiation Exposure written by United States. General Accounting Office and published by . This book was released on 1981 with total page 1452 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Health Effects of Low-level Radiation by : Sōhei Kondō
Download or read book Health Effects of Low-level Radiation written by Sōhei Kondō and published by . This book was released on 1993 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Problems in Assessing the Cancer Risks of Low-level Ionizing Radiation Exposure by : United States. General Accounting Office
Download or read book Problems in Assessing the Cancer Risks of Low-level Ionizing Radiation Exposure written by United States. General Accounting Office and published by . This book was released on 1981 with total page 826 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation Publisher :National Academies Press ISBN 13 :0309133343 Total Pages :422 pages Book Rating :4.3/5 (91 download)
Book Synopsis Health Risks from Exposure to Low Levels of Ionizing Radiation by : Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation
Download or read book Health Risks from Exposure to Low Levels of Ionizing Radiation written by Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation and published by National Academies Press. This book was released on 2006-03-23 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the seventh in a series of titles from the National Research Council that addresses the effects of exposure to low dose LET (Linear Energy Transfer) ionizing radiation and human health. Updating information previously presented in the 1990 publication, Health Effects of Exposure to Low Levels of Ionizing Radiation: BEIR V, this book draws upon new data in both epidemiologic and experimental research. Ionizing radiation arises from both natural and man-made sources and at very high doses can produce damaging effects in human tissue that can be evident within days after exposure. However, it is the low-dose exposures that are the focus of this book. So-called “late” effects, such as cancer, are produced many years after the initial exposure. This book is among the first of its kind to include detailed risk estimates for cancer incidence in addition to cancer mortality. BEIR VII offers a full review of the available biological, biophysical, and epidemiological literature since the last BEIR report on the subject and develops the most up-to-date and comprehensive risk estimates for cancer and other health effects from exposure to low-level ionizing radiation.
Book Synopsis Problems in Assessing the Cancer Risks of Low-level Ionizing Radiation Exposure by : United States. General Accounting Office
Download or read book Problems in Assessing the Cancer Risks of Low-level Ionizing Radiation Exposure written by United States. General Accounting Office and published by . This book was released on 1981 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Analysis of Cancer Risks in Populations Near Nuclear Facilities by : National Research Council
Download or read book Analysis of Cancer Risks in Populations Near Nuclear Facilities written by National Research Council and published by National Academies Press. This book was released on 2012-06-29 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the late 1980s, the National Cancer Institute initiated an investigation of cancer risks in populations near 52 commercial nuclear power plants and 10 Department of Energy nuclear facilities (including research and nuclear weapons production facilities and one reprocessing plant) in the United States. The results of the NCI investigation were used a primary resource for communicating with the public about the cancer risks near the nuclear facilities. However, this study is now over 20 years old. The U.S. Nuclear Regulatory Commission requested that the National Academy of Sciences provide an updated assessment of cancer risks in populations near USNRC-licensed nuclear facilities that utilize or process uranium for the production of electricity. Analysis of Cancer Risks in Populations near Nuclear Facilities: Phase 1 focuses on identifying scientifically sound approaches for carrying out an assessment of cancer risks associated with living near a nuclear facility, judgments about the strengths and weaknesses of various statistical power, ability to assess potential confounding factors, possible biases, and required effort. The results from this Phase 1 study will be used to inform the design of cancer risk assessment, which will be carried out in Phase 2. This report is beneficial for the general public, communities near nuclear facilities, stakeholders, healthcare providers, policy makers, state and local officials, community leaders, and the media.
Book Synopsis Implications of Recent Epidemiologic Studies for the Linear Nonthreshold Model and Radiation Protection by :
Download or read book Implications of Recent Epidemiologic Studies for the Linear Nonthreshold Model and Radiation Protection written by and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Stereotactic Body Radiation Therapy by : Simon S. Lo
Download or read book Stereotactic Body Radiation Therapy written by Simon S. Lo and published by Springer Science & Business Media. This book was released on 2012-08-28 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stereotactic body radiation therapy (SBRT) has emerged as an important innovative treatment for various primary and metastatic cancers. This book provides a comprehensive and up-to-date account of the physical/technological, biological, and clinical aspects of SBRT. It will serve as a detailed resource for this rapidly developing treatment modality. The organ sites covered include lung, liver, spine, pancreas, prostate, adrenal, head and neck, and female reproductive tract. Retrospective studies and prospective clinical trials on SBRT for various organ sites from around the world are examined, and toxicities and normal tissue constraints are discussed. This book features unique insights from world-renowned experts in SBRT from North America, Asia, and Europe. It will be necessary reading for radiation oncologists, radiation oncology residents and fellows, medical physicists, medical physics residents, medical oncologists, surgical oncologists, and cancer scientists.
Book Synopsis Regulatory T Cells in Health and Disease by :
Download or read book Regulatory T Cells in Health and Disease written by and published by Academic Press. This book was released on 2015-11-26 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regulatory T Cells in Health and Disease focuses on the mechanism by which T cells become regulatory T cells, the processes which control the number of regulatory T cells in the blood and tissue, and the ways in which regulatory T cell prevent autoimmune disease and interact with infections and cancer. Contains contributions from leading authorities in the field of regulatory T cell biology Informs and updates on all the latest developments in the field Explores the processes which control the number of regulatory T cells in the blood and tissue, and the ways in which regulatory T cell prevent autoimmune disease and interact with infections and cancer
Author :National Academies of Sciences, Engineering, and Medicine Publisher :National Academies Press ISBN 13 :030949771X Total Pages :143 pages Book Rating :4.3/5 (94 download)
Book Synopsis The Future of Low Dose Radiation Research in the United States by : National Academies of Sciences, Engineering, and Medicine
Download or read book The Future of Low Dose Radiation Research in the United States written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-01-13 with total page 143 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exposures at low doses of radiation, generally taken to mean doses below 100 millisieverts, are of primary interest for setting standards for protecting individuals against the adverse effects of ionizing radiation. However, there are considerable uncertainties associated with current best estimates of risks and gaps in knowledge on critical scientific issues that relate to low dose radiation. The Nuclear and Radiation Studies Board of the National Academies hosted the symposium on The Future of Low Dose Radiation Research in the United States on May 8 and 9, 2019. The goal of the symposium was to provide an open forum for a national discussion on the need for a long-term strategy to guide a low dose radiation research program in the United States. The symposium featured presentations on low dose radiation programs around the world, panel discussions with representatives from governmental and nongovernmental organizations about the need for a low dose radiation research program, reviews of low dose radiation research in epidemiology and radiation biology including new directions, and lessons to be learned from setting up large research programs in non-radiation research fields. This publication summarizes the presentation and discussion of the symposium.
Book Synopsis Immune Damage in Irradiated Mice by : Kelley A. Chambers
Download or read book Immune Damage in Irradiated Mice written by Kelley A. Chambers and published by . This book was released on 1997 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :Michael Heinrich Seegenschmiedt Publisher :Springer Science & Business Media ISBN 13 :3540689435 Total Pages :729 pages Book Rating :4.5/5 (46 download)
Book Synopsis Radiotherapy for Non-Malignant Disorders by : Michael Heinrich Seegenschmiedt
Download or read book Radiotherapy for Non-Malignant Disorders written by Michael Heinrich Seegenschmiedt and published by Springer Science & Business Media. This book was released on 2009-04-15 with total page 729 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume discusses the background and various clinical applications of radiation therapy in the treatment of non-malignant diseases. It documents the radiobiological and physical principles of treatment and the rationale underlying the use of radiotherapy for various disorders of the CNS, head and neck, eye, skin and soft tissues, bone and joints, and vascular system. In so doing, it draws attention to and elucidates the scope for application of radiotherapy beyond the treatment of malignancies. Both the risks and the benefits of such treatment are fully considered, the former ranging from minor clinical problems to life-threatening diseases.
Book Synopsis Inflammation and Immunity in Cancer by : Tsukasa Seya
Download or read book Inflammation and Immunity in Cancer written by Tsukasa Seya and published by Springer. This book was released on 2015-03-26 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book overviews cancer immunity from broad scientific fields, based on the concept that cancer is a sort of by-product of infection, inflammation, and host immune response. The innate and acquired arms of the immune system mainly participate in tumor immune surveillance, and their activation is critically modulated by the situation of the tumor microenvironment. Many types of immune cells join the formation of the microenvironment. In particular, macrophages and dendritic cells enter the tumor mass to be main players in the inflammatory milieu of tumors. After introducing these topics, the book discusses immunotherapy for cancer patients as an outgrowth of this concept of infection and inflammation. With the contributions of leading scientists actively involved in the field of antitumor immunity study, this book encourages readers to understand the mechanism of general cancers based on inflammation and will facilitate prevention and the development of therapeutics for cancer.
Book Synopsis Military Radiobiology by : James J. Conklin
Download or read book Military Radiobiology written by James J. Conklin and published by . This book was released on 1987 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contents: Military Radiobiology: A Perspective; Physical Principles of Nuclear Weapons; Nuclear Weapons Fallout; Ionizing Radiations and Their Interactions with Matter; Cellular Radiation Biology; Radiation Effects on the Lymphohematopoietic System: A Compromise in Immune Competency; Effect of Ionizing Radiation on Gastrointestinal Physiology; Postirradiation Cardiovascular Dysfunction; Acute Radiation Syndrome; The Combined Injury Syndrome; Mechanisms and Management of Infectious Complications of Combined Injury; Diagnosis, Triage, and Treatment of Casualties; Internal Contamination with Medically Significant Radionuclides; Radioprotectants; Psychological Effects of Nuclear Warfare; Effects of Ionizing Radiation on Behavior and the Brain; Nuclear Weapons Accident Response Procedure; Management of Radiation Accidents; Medical Operations in Nuclear War; Low-Level Effects. (Reprints).
