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Liver Innervation And The Neural Control Of Hepatic Function
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Book Synopsis Liver Innervation and the Neural Control of Hepatic Function by : Takashi Shimazu
Download or read book Liver Innervation and the Neural Control of Hepatic Function written by Takashi Shimazu and published by John Libbey Eurotext. This book was released on 1996 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the liver, nutrients taken up from food are utilized for the synthesis of different components of the body, and the waste matter and harmful substances produced are disposed or detoxicated. These functions of the liver must be regulated in accordance with the state of the body. The nervous system plays this regulatory role, one which is reminiscent of the production management system in a factory.
Book Synopsis Liver and Nervous System by : D. Häussinger
Download or read book Liver and Nervous System written by D. Häussinger and published by Springer. This book was released on 1998-06-30 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the Falk Symposium 103, held in Freiburg, Germany, on October 4-5, 1997.
Book Synopsis Textbook of Hepatology by : Juan Rodés
Download or read book Textbook of Hepatology written by Juan Rodés and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 2359 pages. Available in PDF, EPUB and Kindle. Book excerpt: THE encyclopedic guide to hepatology – for consultation by clinicians and basic scientists Previously the Oxford Textbook of Clinical Hepatology, this two-volume textbook is now with Blackwell Publishing. It covers basic, clinical and translational science (converting basic science discoveries into the practical applications to benefit people). Edited by ten leading experts in the liver and biliary tract and their diseases, along with outstanding contributions from over 200 international clinicians, this text has global references, evidence and extensive subject matter – giving you the best science and clinical practice discussed by the best authors. It includes unique sections on: Symptoms and signs in liver disease Industrial diseases affecting the liver The effects of diseases of other systems on the liver The effects of liver diseases on other systems It's bigger and more extensive than other books and discusses new areas in more depth such as stem cells, genetics, genomics, proteomics, transplantation, mathematics and much more. Plus, it comes with a fully searchable CD ROM of the entire content. Click here to view a sample chapter on the liver and coagulation
Book Synopsis Cellular Osmolytes by : Laishram Rajendrakumar Singh
Download or read book Cellular Osmolytes written by Laishram Rajendrakumar Singh and published by Springer. This book was released on 2017-05-16 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides essential information on improving protein folding/stability, which is a result of the balance between the intra-molecular interactions of protein functional groups and their interactions with the solvent environment. The protein folding solvent environment mainly consists of salts, small molecule compounds, metabolites, molecular chaperones and other chemical species. Therefore, subtle change in the composition of the environment will alter the protein folding process. The importance of the solvent environment in protein folding is precisely due to the fact that various disease-causing proteopathies can be reversed by manipulating the solvent environment of the malfolded proteins. Hostile environmental stresses represent one of the basic causes of such challenges in protein folding or misfolding. Since cells commonly encounter extreme environmental fluctuations, it is crucial that they equip themselves with strategies to circumvent the hostile environmental conditions. Nature has developed many strategies to ensure that the complex and challenging protein folding reaction occurs with adequate efficiency and fidelity for the success of the organism. Among the strategies employed in a wide range of species and cell types is the elaboration of small organic molecules called osmolytes. Additionally, recent advances have also revealed that certain specific osmolytes might be key biomarkers of cancer, infectious diseases and vaccine flocculation. In fact, a large pool of data has been generated regarding their potential for the therapeutic intervention of neurodegenerative diseases and other metabolic disorders caused by protein aggregation or proteostasis failure. Reflecting the multiple applications of these small molecules in the health and other industries, this book combines contributions by respected leaders in the field and will help to inspire college students, basic researchers, and clinicians to translate these biological roles of osmolytes into clinical practice. It will also shed light on some important future prospects of osmolytes like their role as drug excipients and provide a deeper understanding of their mechanism of action in the prevention of neuro-degenerative diseases.
Book Synopsis Regulation of Hepatic Metabolism by : K. Jungermann
Download or read book Regulation of Hepatic Metabolism written by K. Jungermann and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: The liver is an exceptionally complex and diverse organ that functions both as an exocrine and an endocrine gland. It secretes bile, which contains many con stituents in addition to bile salts, and it synthesizes and releases many substances in response to the body's demands, including prohormones, albumin, clotting factors, glucose, fatty acids, and various lipoproteins. It has a dual blood supply providing a rich mixture of nutrients and other absorbed substances via the portal vein and oxygen-rich blood via the hepatic artery. This functional heterogeneity is accompanied by cellular heterogeneity. The liver contains many cell types including hepatic parachymal cells, Kiipffer cells, Ito cells, and endothelial cells. The most abundant cell type, the parenchymal cells, are biochemically and structurally heterogeneous. The cells in the oxygen-rich areas of the portal triad appear more dependent on oxidative metabolism, whereas those around the central vein (pericentral, perivenous, or centrolobular areas) are more dependent upon an anaerobic mechanism. Throughout this volume the latter three terms are used synonymously by various authors to indicate the five to eight layers of cells radiating from the central vein. Structural and metabolic heterogeneity of hepatic parenchymal cells has been demonstrated by a variety of approaches, including histochemical, ultra structural, and ultramicrobiochemical studies. This microheterogeneity is linked to the physiological functions of the liver and its response to injurious substances.
Book Synopsis Comprehensive Human Physiology by : Rainer Greger
Download or read book Comprehensive Human Physiology written by Rainer Greger and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 2478 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Human Physiology is a significantly important publication on physiology, presenting state-of-the-art knowledge about both the molecular mechanisms and the integrative regulation of body functions. This is the first time that such a broad range of perspectives on physiology have been combined to provide a unified overview of the field. This groundbreaking two-volume set reveals human physiology to be a highly dynamic science rooted in the ever-continuing process of learning more about life. Each chapter contains a wealth of original data, clear illustrations, and extensive references, making this a valuable and easy-to-use reference. This is the quintessential reference work in the fields of physiology and pathophysiology, essential reading for researchers, lecturers and advanced students.
Download or read book EJB Reviews written by P. Christen and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the mid-1980s the European Journal of Biochemistry set out to publish review articles. The enterprise proved successful resulting in high-level reviews written by well-known scientists appearing in the Journal. The reviews represent emerging and rapidly growing fields of research in fundamental as well as applied areas of biochemistry, such as medicine, biotechnology, agriculture and nutrition. Novel methodological andtechnological approaches which stimulate biochemical research are also included. The authors of the reviews are explicitly asked to be critical, selective, evaluative and interdisciplinarily oriented. The reviews should encourage young scientists toward independent and creative thinking, and inform active investigators about the state of the art in a given field.
Book Synopsis Canadian Journal of Physiology and Pharmacology by :
Download or read book Canadian Journal of Physiology and Pharmacology written by and published by . This book was released on 2002-09 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Bioelectronic Medicine by : Valentin A. Pavlov
Download or read book Bioelectronic Medicine written by Valentin A. Pavlov and published by Perspectives Cshl. This book was released on 2019 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Cold Spring Harbor perspectives in medicine."
Book Synopsis Hepatic Circulation by : W. Wayne Lautt
Download or read book Hepatic Circulation written by W. Wayne Lautt and published by Morgan & Claypool Publishers. This book was released on 2009-11-17 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Hepatic circulation is unique among vascular beds. The most obvious unique features include the dual vascular supply; the mechanism of intrinsic regulation of the hepatic artery (the hepatic arterial buffer response); the fact that portal blood flow, supplying two thirds of liver blood flow, is not controlled directly by the liver; the fact that 20% of the cardiac output rushes through the most vascularized organ in the body, driven by a pressure gradient of only a few millimeters of mercury; the extremely distensible capacitance and venous resistance sites; the unidirectional acinar blood flow that regulates parenchymal cell metabolic specialization; and the high concentration of macrophagic (Kupffer) cells filtering the blood. The liver is the only organ reported to have regional blood flow monitored by the autonomic nervous system. This mechanism, when dysfunctional, accounts for the hepatorenal syndrome and offers a mechanistic therapeutic target to treat this syndrome. The trigger for liver regeneration is dependent on hepatic hemodynamics so that chronic liver blood flow regulates liver cell mass. In severe liver disease, the whole body circulation is reorganized, by forming portacaval shunts, to accommodate the increased intrahepatic venous resistance. These shunts protect the venous drainage of the splanchnic organs but lead to loss of major regulatory roles of the liver. The development of knowledge of the hepatic vasculature is presented from a historical perspective with modern concepts summarized based on the perspective of the author's four decades of devotion to this most marvelous of organs. Table of Contents: Acknowledgements / Historical Perspectives / Overview / Fluid Exchange / Capacitance / Resistance in the Hepatic Artery / Resistance in the Venous System / Fetal and Neonatal Hepatic Circulation / In Vivo Pharmacodynamic Approaches / Nitric Oxide / Adenosine / Hepatic Nerves / Hepatic Circulation and Toxicology / Hepatorenal Syndrome / Integrative Hepatic Response to Hemorrhage / Blood Flow Regulation of Hepatocyte Proliferation / Multiple Mechanisms Maintaining a Constant Hepatic Blood Flow to Liver Mass Ratio / Pathopharmacology and Repurposing Drugs as a Research Strategy / References
Download or read book The Cumulative Book Index written by and published by . This book was released on 1997 with total page 2312 pages. Available in PDF, EPUB and Kindle. Book excerpt: A world list of books in the English language.
Book Synopsis Textbook of Medical Physiology_3rd Edition-E-book by : Indu Khurana
Download or read book Textbook of Medical Physiology_3rd Edition-E-book written by Indu Khurana and published by Elsevier Health Sciences. This book was released on 2019-11-11 with total page 1171 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third edition of this book incorporates thoroughly revised and updated text, organized into twelve sections and arranged in three parts. Part I: General Physiology includes one section having five chapters. Part II: Systemic Physiology has been arranged into ten sections, one on each body system. Part III: Specialized integrated physiology includes one section comprising of seven chapters. . - Complete and up-to-date text incorporating recent advances. - Illustrated by more than 1100 clear line diagrams. - Complemented with numerous tables and flowcharts for quick comprehension. - Applied aspects, highlighted in the boxes, have been expanded and updated with recent molecular concepts on pathophysiology, advances in investigations and therapeutic principles. - Additional important information has been highlighted as important notes. The above features of this book make it an indispensable text for postgraduates in Physiology. Candidate preparing for PG entrance examination would also find it as an authentic reference source. Complimentary access to full e-book.
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1972 with total page 1354 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Pituitary Adenylate Cyclase-Activating Polypeptide by : Hubert Vaudry
Download or read book Pituitary Adenylate Cyclase-Activating Polypeptide written by Hubert Vaudry and published by Springer Science & Business Media. This book was released on 2003 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pituitary Adenylate Cyclase-Activating Polypeptide is the first volume to be written on the neuropeptide PACAP. It covers all domains of PACAP from molecular and cellular aspects to physiological activities and promises for new therapeutic strategies. Pituitary Adenylate Cyclase-Activating Polypeptide is the twentieth volume published in the Endocrine Updates book series under the Series Editorship of Shlomo Melmed, MD.
Book Synopsis Kokuritsu Kokkai Toshokan shozō kagaku gijutsu kankei Ōbun kaigiroku mokuroku by : Kokuritsu Kokkai Toshokan (Japan)
Download or read book Kokuritsu Kokkai Toshokan shozō kagaku gijutsu kankei Ōbun kaigiroku mokuroku written by Kokuritsu Kokkai Toshokan (Japan) and published by . This book was released on 1997 with total page 1596 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Textbook of Medical Physiology - E-Book by : Indu Khurana
Download or read book Textbook of Medical Physiology - E-Book written by Indu Khurana and published by Elsevier Health Sciences. This book was released on 2024-08-15 with total page 1261 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fourth edition of this well-known book has been thoroughly revised and updated as per the suggestions and feedback from students and teachers. The text has been arranged in three parts and each part has been further subdivided in twelve sections and seventy-eight chapters:Part I: General Physiology includes one section having five chapters.Part II: Systemic Physiology has been arranged into ten sections, one on each body system.Part III: Specialized integrated physiology includes one section comprising of eight chapters.New to This Edition• Addition of a new chapter on Physiology of Yoga explains effectual relationship between aspects of yoga practice and human physiology.• New applied aspects to emphasize the clinical significance of physiology have been included.• Additional important notes have been threaded, re-emphasizing the core concepts.• Self-assessment of the topics studied have been introduced at the end of each chapter helps revision.• Clinical cases are presented for problem-based learning and knowledge at the end of chapters.Salient Features• Extensive revision of chapters as per the basis on scientific advancement and subject requirement.• 1140 Illustrations in the form of line diagrams, flowcharts, clinical photographs incorporated to enhance visual representation.• Applied aspects, highlighted in the boxes presented with recent molecular concepts on pathophysiology, advances in investigative and therapeutic principles.• Important notes highlight the additional valuable information, wherever relevant for quick revision.Online resource at www.medenact.com• Complimentary access to full ebook.
Book Synopsis Neural Control of Renal Function by : Ulla Kopp
Download or read book Neural Control of Renal Function written by Ulla Kopp and published by Morgan & Claypool Publishers. This book was released on 2011 with total page 99 pages. Available in PDF, EPUB and Kindle. Book excerpt: The kidney is innervated with efferent sympathetic nerve fibers reaching the renal vasculature, the tubules, the juxtaglomerular granular cells, and the renal pelvic wall. The renal sensory nerves are mainly found in the renal pelvic wall. Increases in efferent renal sympathetic nerve activity reduce renal blood flow and urinary sodium excretion by activation of α1-adrenoceptors and increase renin secretion rate by activation of β1-adrenoceptors. In response to normal physiological stimulation, changes in efferent renal sympathetic nerve activity contribute importantly to homeostatic regulation of sodium and water balance. The renal mechanosensory nerves are activated by stretch of the renal pelvic tissue produced by increases in renal pelvic tissue of a magnitude that may occur during increased urine flow rate. Activation of the sensory nerves elicits an inhibitory renorenal reflex response consisting of decreases in efferent renal sympathetic nerve activity leading to natriuresis. Increasing efferent sympathetic nerve activity increases afferent renal nerve activity which, in turn, decreases efferent renal sympathetic nerve activity by activation of the renorenal reflexes. Thus, activation of the afferent renal nerves buffers changes in efferent renal sympathetic nerve activity in the overall goal of maintaining sodium balance. In pathological conditions of sodium retention, impairment of the inhibitory renorenal reflexes contributes to an inappropriately increased efferent renal sympathetic nerve activity in the presence of sodium retention. In states of renal disease or injury, there is a shift from inhibitory to excitatory reflexes originating in the kidney. Studies in essential hypertensive patients have shown that renal denervation results in long-term reduction in arterial pressure, suggesting an important role for the efferent and afferent renal nerves in hypertension. Table of Contents: Part I: Efferent Renal Sympathetic Nerves / Introduction / Neuroanatomy / Neural Control of Renal Hemodynamics / Neural Control of Renal Tubular Function / Neural Control of Renin Secretion Rate / Part II: Afferent Renal Sensory Nerves / Introduction / Neuroanatomy / Renorenal Reflexes / Mechanisms Involved in the Activation of Afferent Renal Sensory Nerves / Part III: Pathophysiological States / Efferent Renal Sympathetic Nerves / Afferent Renal Sensory Nerves / Conclusions / References
