Liv And Mouse

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Liv and Mouse

Author : Olga Zagulova
Publisher : Independently Published
ISBN 13 :
Total Pages : 24 pages
Book Rating : 4.4/5 (818 download)

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Book Synopsis Liv and Mouse by : Olga Zagulova

Download or read book Liv and Mouse written by Olga Zagulova and published by Independently Published. This book was released on 2021-11-26 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt: Liv and Mouse is a humorous children's book about kindness and imagination. Short rhyming stories describe the main character's adventures with her family members and demonstrate the love they have for each other. As Liv talks about family, her best friend Mouse is always by her side, joining all of the fun activities. Liv and Mouse are inseparable and have a unique bond, as Liv truly believes that Mouse is alive. Whether Liv is playing dress up or riding a bike, Mouse is near her, highlighting the importance of friendship in children's lives. Liv shares stories about her Mommy, Daddy, Grandma, Grandpa, Little Brother and her Doggy Rozzi. This vivid book reminds the reader about the significance of family connections and brings out the pureness of children's hearts through humor and storytelling. The poetry came to the author during countless hours spent chatting and laughing with her own children, Olivia and Maximus, who were the inspiration behind the stories. Author's vision and ability to capture her kids' memories created the foundation for this funny and kind-hearted book. Liv and Mouse offers a glimpse into Liv's family and allows readers to draw parallels with their own lives. As you read and smile with Liv, do any of the characters remind you of your own family members?

Humanized Mice

Author : Tatsuji Nomura
Publisher : Springer Science & Business Media
ISBN 13 : 3540756477
Total Pages : 209 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Humanized Mice by : Tatsuji Nomura

Download or read book Humanized Mice written by Tatsuji Nomura and published by Springer Science & Business Media. This book was released on 2008-03-11 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: The term humanized mouse in this text refers to a mouse in which human tissues and cells have been transplanted and show the same biological function as they do in the human body. That is, the physiological properties and functions of tra- planted human tissues and cells can be analyzed in the mouse instead of using a living human body. It should therefore be possible to study the pathophysiology and treatment of human diseases in mice with good reproducibility. Thus, the hum- ized mouse can be used as a potent tool in both basic and clinical research in the future. The development of appropriate immunodeficient mice has been indispensable in the creation of the humanized mouse, which has been achieved through many years of efforts by several laboratories. The first stage on the road to the humanized mouse was the report on nude mice by Isaacson and Cattanach in 1962. Thereafter, nude mice were studied in detail by Falanagan and, in 1968, Pantelouris found that these mice have no thymus gland, which suggested that the mice lack transplan- tion immunity against xenografts such as human hematopoietic stem cells. At the Nude Mouse Workshops (organized by Regard, Povlsen, Nomura and colleagues) that were held nine times between 1972 and 1997, the possibility of creating a humanized mouse using nude mice was extensively examined. The results, however, showed that certain human cancers can be engrafted in nude mice, but unfortunately engraftment of normal human tissue was almost impossible.

Liv and Mouse

Author : Olga Zagulova
Publisher :
ISBN 13 : 9781087985039
Total Pages : 0 pages
Book Rating : 4.9/5 (85 download)

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Book Synopsis Liv and Mouse by : Olga Zagulova

Download or read book Liv and Mouse written by Olga Zagulova and published by . This book was released on 2021-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Humanized Mice for HIV Research

Author : Larisa Y. Poluektova
Publisher : Springer
ISBN 13 : 1493916556
Total Pages : 536 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Humanized Mice for HIV Research by : Larisa Y. Poluektova

Download or read book Humanized Mice for HIV Research written by Larisa Y. Poluektova and published by Springer. This book was released on 2015-02-18 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last several years the field of humanized mice has matured and developed into an essential component of translational research for HIV/AIDS. Humanized mice serve both as vehicles for discovery and as highly sophisticated platforms for biomedical research. In addition, humanized mice have demonstrated outstanding potential for the investigation of critical aspects of the infection and pathogenesis of the hepatitis and herpes viruses, as well as highly relevant microbial infections such as tuberculosis and malaria. Humanized Mice for HIV Research provides a comprehensive presentation of the history, evolution, applications, and current state of the art of this unique animal model. An expansion of twelve review articles that were published in Humanized Mice by Springer in 2008 (Eds: Nomura T, Watanabe T, Habu S), this book expertly captures the outstanding progress that has been made in the development, improvement, implementation, and validation of humanized mouse models. The first two parts of this book cover the basics of human-to-mouse xenotransplantation biology, and provide critical information about human immune cell development and function based on individual models created from different immunodeficient strains of mice. The third and fourth parts investigate HIV-1 biology, including different routes of transmission, prevention, treatment, pathogenesis, and the development of adaptive immunity in humanized mice. The fifth part shows the broad applicability of humanized mice for therapeutic development, from long-acting antiretroviral combinations to genetic manipulations with human cells and cell-based approaches. The sixth part includes liver tissue engineering and the expansion of humanized mice for many other human cell-tropic pathogens.

Handbook of Animal Models of Infection

Author : Merle A. Sande
Publisher : Academic Press
ISBN 13 : 0080533558
Total Pages : 1169 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Handbook of Animal Models of Infection by : Merle A. Sande

Download or read book Handbook of Animal Models of Infection written by Merle A. Sande and published by Academic Press. This book was released on 1999-05-28 with total page 1169 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Animal Models of Infection is a complete revision of a three-volume text that was published in 1986. It incorporates the major advances in the field during the past decade, in particular those concerning molecular biological procedures and new models that have been developed. It focuses on both methods and techniques, which makes it an essential and comprehensive reference as well as a benchtop manual. The Handbook will help investigators save time and effort in formulating an approach to test a new potential therapeutic agent or combination of agents for in vivo efficacy and to position the therapy for specific infections where it may have therapeutic promise. The book is divided into five sections; the first covering the general methodologies, followed by sections describing experimental bacterial, mycotic, parasitic, and viral infections. - Discusses ethical and safety aspects in an introductory background section - Covers principles of animal care and current techniques appropriate for the use of animal models of infection - Details a wide range of animals including rodents, rabbits, cats, and primates - Provides hands-on descriptions of how to set up the model - Discusses the major advantages and limitations of each model - Ensures full coverage of bacterial, fungal, viral, and parasitic infections

Lysterium

Author : Bethany Shehorn
Publisher : iUniverse
ISBN 13 : 1450283403
Total Pages : 149 pages
Book Rating : 4.4/5 (52 download)

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Book Synopsis Lysterium by : Bethany Shehorn

Download or read book Lysterium written by Bethany Shehorn and published by iUniverse. This book was released on 2011-02-03 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite the devastating loss of her mother as a teenager, Liv Worthington has grown to become a successful newspaper editorliving a normal workaholic life in New York City. But her secure and comfortable existence changes the day she meets Wes, a handsome stranger who has been following her. This chance meeting with Wes turns Livs life upside down and forces her grandmother to reveal a long-held family secreta secret linked to her mothers deaththat could have even more dire consequences. Liv discovers that the fairytales her grandmother spun years ago about another world called Lysterium are actually true. For more than sixty years, she has been harboring Lysteriums book of prophecy, a tome that speaks about a woman in the family who would overthrow the evil Umaro and restore peace to Lysterium. Liv discovers that she is the woman spoken about in the bookthe key to Lysteriums salvation or demise. As her past unravels, Liv must make a difficult decision that will not only greatly affect her future, but Lysteriums as well.

Innovative Medicine

Author : Kazuwa Nakao
Publisher : Springer
ISBN 13 : 4431556516
Total Pages : 330 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis Innovative Medicine by : Kazuwa Nakao

Download or read book Innovative Medicine written by Kazuwa Nakao and published by Springer. This book was released on 2015-10-13 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is also considerable demand for progress in drug research, new surgical procedures, and new clinical devices and equipment. While the original research target may be rare diseases, it is also important to apply those findings more broadly to common diseases. The book covers a wide range of topics and is organized into three complementary parts. The first part is basic research for innovative medicine, the second is translational research for innovative medicine, and the third is new technology for innovative medicine. This book helps to understand innovative medicine and to make progress in its realization.

Gene Therapy for HIV

Author : Gerhard Bauer
Publisher : Springer Science & Business Media
ISBN 13 : 1493904345
Total Pages : 77 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Gene Therapy for HIV by : Gerhard Bauer

Download or read book Gene Therapy for HIV written by Gerhard Bauer and published by Springer Science & Business Media. This book was released on 2014-02-07 with total page 77 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Brief describes the concept and realization of gene therapy for HIV from the unique historic perspective and insight of two pioneers of the clinical applications of stem cell gene therapy for HIV. Gerhard Bauer applied ribozyme-anti-HIV and other vectors to manufacture clinical grade, HIV-resistant hematopoietic stem cells for the first patients that received stem cell gene therapy for HIV, including the first child in the world and the first fully marrow-ablated HIV infected patient. Joseph Anderson developed the most recent and most potent combination anti-HIV lentiviral vectors and pluripotent stem cell applications for HIV gene therapy and tested these in the appropriate in vitro and vivo models, paving the way for novel HIV gene therapy approaches to possibly cure patients. In Gene Therapy for HIV, Bauer and Anderson discuss the unique aspects of this therapy, including its limitations and proper safety precautions and outline a path for a possible functional cure for HIV using stem cell gene therapy based on a cure already achieved with a bone marrow stem cell transplantation performed in Germany using donor stem cells with a naturally arising CCR5 mutation. In addition, the Brief provides a thorough and methodical explanation of the basics of gene therapy, gene therapy vector development, in vitro and in vivo models for HIV gene therapy and clinical applications of HIV gene therapy, including Good Manufacturing Practices.

Xenotransplantation

Author : David K.C. Cooper
Publisher : Springer Science & Business Media
ISBN 13 : 3642605729
Total Pages : 877 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Xenotransplantation by : David K.C. Cooper

Download or read book Xenotransplantation written by David K.C. Cooper and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 877 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a time ofexcitement and progress in the field ofxenotransplantation. The work described in this book traces the development of the science of cross-spe cies transplantation, summarizes the current state ofour knowledge, and focuses on approaches directed toward future clinical application. The important question is not whether xenotransplantation will succeed, but rather how and under what circumstances xenografts will provide predictable enough results to warrant clinical application. The fact that the best results to date in clinical xenografting were achieved over three decades ago should not be a matter of discouragement, but rather a stimulus to apply new approaches to this area of work. The shortage of human organs for transplantation is cited frequently as the driving force behind the increased interest in xenotransplantation. This shortage is an undeniable fact, but there are additional potential advantages of xenotrans plantation, such as the ability to schedule replacement surgery on an elective basis and the modification of animals, organs, and tissues to improve acceptabil ity in the human host. The advances in the basic science ofxenotransplantation outlined in this book give hope that the immunologic barriers to xenotransplantation will be overcome and that transplanted organs and tissues will succeed consistently in humans. However, if our experience with human allografts provides an analogy, we may anticipate that clinical progress in xenografts will be plagued by failures and rewarded by successes, often without a complete understanding of the mechan isms involved.

HIV-Host Interactions

Author : Theresa Li-Yun Chang
Publisher : BoD – Books on Demand
ISBN 13 : 9533074426
Total Pages : 380 pages
Book Rating : 4.5/5 (33 download)

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Book Synopsis HIV-Host Interactions by : Theresa Li-Yun Chang

Download or read book HIV-Host Interactions written by Theresa Li-Yun Chang and published by BoD – Books on Demand. This book was released on 2011-11-02 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: HIV remains the major global health threat, and neither vaccine nor cure is available. Increasing our knowledge on HIV infection will help overcome the challenge of HIV/AIDS. This book covers several aspects of HIV-host interactions in vitro and in vivo. The first section covers the interaction between cellular components and HIV proteins, Integrase, Tat, and Nef. It also discusses the clinical relevance of HIV superinfection. The next two chapters focus on the role of innate immunity including dendritic cells and defensins in HIV infection followed by the section on the impact of host factors on HIV pathogenesis. The section of co-infection includes the impact of Human herpesvirus 6 and Trichomonas vaginalis on HIV infection. The final section focuses on generation of HIV molecular clones that can be used in macaques and the potential use of cotton rats for HIV studies.

Readers' Guide to Periodical Literature

Author : Anna Lorraine Guthrie
Publisher :
ISBN 13 :
Total Pages : 1260 pages
Book Rating : 4.A/5 ( download)

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Book Synopsis Readers' Guide to Periodical Literature by : Anna Lorraine Guthrie

Download or read book Readers' Guide to Periodical Literature written by Anna Lorraine Guthrie and published by . This book was released on 1910 with total page 1260 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Drug Delivery and Development of Anti-HIV Microbicides

Author : Jose das Neves
Publisher : CRC Press
ISBN 13 : 9814463574
Total Pages : 679 pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis Drug Delivery and Development of Anti-HIV Microbicides by : Jose das Neves

Download or read book Drug Delivery and Development of Anti-HIV Microbicides written by Jose das Neves and published by CRC Press. This book was released on 2014-10-16 with total page 679 pages. Available in PDF, EPUB and Kindle. Book excerpt: The worldwide impact of HIV/AIDS is well recognized. This book provides for the first time a thorough and critical overview of current aspects, recent developments, and trends in the formulation and drug delivery concerning anti-HIV microbicides by leading scientists in the field. Additionally, pertinent regulatory aspects and socioeconomical issue

Principles of Tissue Engineering

Author : Robert Lanza
Publisher : Academic Press
ISBN 13 : 0123983703
Total Pages : 1937 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Principles of Tissue Engineering by : Robert Lanza

Download or read book Principles of Tissue Engineering written by Robert Lanza and published by Academic Press. This book was released on 2013-10-17 with total page 1937 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its fourth edition, Principles of Tissue Engineering has been the definite resource in the field of tissue engineering for more than a decade. The fourth edition provides an update on this rapidly progressing field, combining the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation by the world's experts of what is currently known about each specific organ system. As in previous editions, this book creates a comprehensive work that strikes a balance among the diversity of subjects that are related to tissue engineering, including biology, chemistry, material science, and engineering, among others, while also emphasizing those research areas that are likely to be of clinical value in the future. This edition includes greatly expanded focus on stem cells, including induced pluripotent stem (iPS) cells, stem cell niches, and blood components from stem cells. This research has already produced applications in disease modeling, toxicity testing, drug development, and clinical therapies. This up-to-date coverage of stem cell biology and other emerging technologies –such as brain-machine interfaces for controlling bionics and neuroprostheses– is complemented by a series of new and updated chapters on recent clinical experience in applying tissue engineering, as well as a new section on the application of tissue-engineering techniques for food production. The result is a comprehensive textbook that will be useful to students and experts alike. - Includes new chapters on biomaterial-protein interactions, nanocomposite and three-dimensional scaffolds, skin substitutes, spinal cord, vision enhancement, and heart valves - Offers expanded coverage of adult and embryonic stem cells of the cardiovascular, hematopoietic, musculoskeletal, nervous, and other organ systems - Full-color presentation throughout

Environment, Chemistry, and metabolism

Author : Harry Gelboin
Publisher : Elsevier
ISBN 13 : 032315056X
Total Pages : 433 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Environment, Chemistry, and metabolism by : Harry Gelboin

Download or read book Environment, Chemistry, and metabolism written by Harry Gelboin and published by Elsevier. This book was released on 2012-12-02 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polycyclic Hydrocarbons and Cancer, Volume 1: Environment, Chemistry, and Metabolism brings together information from many diverse disciplines in the environmental, chemical, biological, and medical sciences to provide a comprehensive account of the link between polycyclic aromatic hydrocarbons (PAHs) and cancer. This volume consists of 19 chapters divided into seven sections based on the following themes: Energy Sources; Environmental Occurrence and Monitoring; Tobacco Carcinogenesis; Chemistry, Carcinogenicity, and Theory; Metabolism and Activation; Enzymology; and Pharmacokinetics. The first three chapters focus on the energy sources, occurrence and surveillance, and environmental monitoring of PAHs. The discussion then turns to the link between smoking and cancer; the carcinogenicity of 5-methylchrysene; synthesis and reactions of diol epoxides and related metabolites of carcinogenic hydrocarbons; and enzymes of oxygenation. The final chapter is devoted to the pharmacokinetics of chemically reactive metabolites. This book will be of interest to investigators and educators concerned with scientific aspects of PAH research; government officials and elected representatives as well as industry leaders who must confront and solve the problems related to PAHs; and others in various fields such as chemistry, environmental science, biochemistry and enzymology, pharmacology, molecular and cell biology, and genetics.

Translational Immunology

Author : Seng-Lai Tan
Publisher : Academic Press
ISBN 13 : 0128017570
Total Pages : 386 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Translational Immunology by : Seng-Lai Tan

Download or read book Translational Immunology written by Seng-Lai Tan and published by Academic Press. This book was released on 2015-11-18 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Immunology: Mechanisms and Pharmacologic Approaches highlights and summarizes the most important advances in human immunology, clinical translations, new tools to analyze therapeutic targets, and new pharmacological approaches for autoimmunity, inflammatory disorders, and cancer. The book is an essential resource for those seeking to understand the potential translational applications of burgeoning studies in human immunology, helping readers make sense of the existing and emerging scientific advances. The book grounds fundamental science in the translational realm, providing insights from world renowned researchers at the top of their game in their respective fields, in both industry and academic settings. Readers will gain an understanding of the rationale and mechanisms underlying current and emerging pharmacologic approaches for interventional immunology, the gaps therein, and new ideas for better and safer therapeutic approaches, and physicians will glean information about pharmacological limitations in altering disease progression and complications. This reference on the translational realization of the burgeoning findings in immunology provides a go-to reference for experienced professional clinicians, researchers, industry scientists, and those seeking more information on the field. - Delivers comprehensive coverage of seminal human immunology discoveries and the resulting impact on therapeutic strategies - Presents potential novel targets and approaches for clinical applications in organ specific and systemic autoimmunity, transplant rejection, cancer, and vaccine development - Discusses lessons learned from successful and failed clinical trials with specific interventions, including pharmacological issues and limitations, and complications due to immunosuppression - Provides information on new strategies and outstanding issues that should be addressed in future research

United States Naval Medical Bulletin

Author :
Publisher :
ISBN 13 :
Total Pages : 1336 pages
Book Rating : 4.:/5 (29 download)

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Book Synopsis United States Naval Medical Bulletin by :

Download or read book United States Naval Medical Bulletin written by and published by . This book was released on 1945 with total page 1336 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Introduction to Statistical Data Analysis for the Life Sciences

Author : Claus Thorn Ekstrom
Publisher : CRC Press
ISBN 13 : 1482238942
Total Pages : 526 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Introduction to Statistical Data Analysis for the Life Sciences by : Claus Thorn Ekstrom

Download or read book Introduction to Statistical Data Analysis for the Life Sciences written by Claus Thorn Ekstrom and published by CRC Press. This book was released on 2014-11-06 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Hands-On Approach to Teaching Introductory StatisticsExpanded with over 100 more pages, Introduction to Statistical Data Analysis for the Life Sciences, Second Edition presents the right balance of data examples, statistical theory, and computing to teach introductory statistics to students in the life sciences. This popular textbook covers the m