Polyfunctional Cytokines

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 0470514272
Total Pages : 290 pages
Book Rating : 4.4/5 (75 download)

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Book Synopsis Polyfunctional Cytokines by : Gregory R. Bock

Download or read book Polyfunctional Cytokines written by Gregory R. Bock and published by John Wiley & Sons. This book was released on 2008-04-30 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experts from a variety of areas compare and discuss IL-6 and LIF in order to provide a new understanding of their modes of action, the significance of their polyfunctionalization--why the body chooses to use one molecule to regulate various cell types--and their functional overlap. Covers such topics as actions of IL-6 and LIF on lymphoid populations, on megakaryocyte and platelet production, on bone metabolism, their effects on leukemic cells and much more. Includes contributions from researchers working on a variety of cell types and organ systems along with potential clinical applications regarding these two factors.

Molecular Exercise Physiology

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Author :
Publisher : Routledge
ISBN 13 : 1351617001
Total Pages : 549 pages
Book Rating : 4.3/5 (516 download)

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Book Synopsis Molecular Exercise Physiology by : Adam P Sharples

Download or read book Molecular Exercise Physiology written by Adam P Sharples and published by Routledge. This book was released on 2022-05-11 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fully revised and expanded, the second edition of Molecular Exercise Physiology offers a student-friendly introduction. It introduces a history documenting the emergence of molecular biology techniques to investigate exercise physiology, the methodology used, exercise genetics and epigenetics, and the molecular mechanisms that lead to adaptation after different types of exercise, with explicit links to outcomes in sport performance, nutrition, physical activity and clinical exercise. Structured around key topics in sport and exercise science and featuring contributions from pioneering scientists, such as Nobel Prize winners, this edition includes new chapters based on cutting-edge research in epigenetics and muscle memory, satellite cells, exercise in cancer, at altitude, and in hot and cold climates. Chapters include learning objectives, structured guides to further reading, review questions, overviews of work by key researchers and box discussions from important pioneers in the field, making it a complete resource for any molecular exercise physiology course. The book includes cell and molecular biology laboratory methods for dissertation and research projects in molecular exercise physiology and muscle physiology. This book is essential reading for upper-level undergraduate or postgraduate courses in cellular and molecular exercise physiology and muscle physiology. It is a valuable resource for any student with an advanced interest in exercise physiology in both sport performance and clinical settings.

Handbook of Dietary Phytochemicals

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Publisher : Springer
ISBN 13 : 9789811541476
Total Pages : 1953 pages
Book Rating : 4.5/5 (414 download)

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Book Synopsis Handbook of Dietary Phytochemicals by : Jianbo Xiao

Download or read book Handbook of Dietary Phytochemicals written by Jianbo Xiao and published by Springer. This book was released on 2021-09-02 with total page 1953 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes recent advances in the chemistry, bioactivity, nutrition, and functional aspects of dietary phytochemicals, as well as the health and functional aspects of foods rich in phytochemicals. Consisting of forty-four chapters, it discusses the different chemical types of phytochemicals in our diets and food and presents data collected from animal or human experiments that are directly related to human health. Each chapter covers the chemistry, epidemiological study, bioavailability, bioactivity (animal experiments) function in humans and safety, as well as products on the market. Moreover, the more than 200 figures make it easy to grasp the main findings in each area.

Muscle Atrophy

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Author :
Publisher : Springer
ISBN 13 : 9811314357
Total Pages : 618 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis Muscle Atrophy by : Junjie Xiao

Download or read book Muscle Atrophy written by Junjie Xiao and published by Springer. This book was released on 2018-11-02 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book addresses the development of muscle atrophy, which can be caused by denervation, disuse, excessive fasting, aging, and a variety of diseases including heart failure, chronic kidney diseases and cancers. Muscle atrophy reduces quality of life and increases morbidity and mortality worldwide. The book is divided into five parts, the first of which describes the general aspects of muscle atrophy including its characteristics, related economic and health burdens, and the current clinical therapy. Secondly, basic aspects of muscle atrophy including the composition, structure and function of skeletal muscle, muscle changes in response to atrophy, and experimental models are summarized. Thirdly, the book reviews the molecular mechanisms of muscle atrophy, including protein degradation and synthesis pathways, noncoding RNAs, inflammatory signaling, oxidative stress, mitochondria signaling, etc. Fourthly, it highlights the pathophysiological mechanisms of muscle atrophy in aging and disease. The book’s fifth and final part covers the diagnosis, treatment strategies, promising agents and future prospects of muscle atrophy. The book will appeal to a broad readership including scientists, undergraduate and graduate students in medicine and cell biology.

Spinal Muscular Atrophy

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Author :
Publisher : Academic Press
ISBN 13 : 0128036869
Total Pages : 508 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Spinal Muscular Atrophy by : Charlotte J Sumner

Download or read book Spinal Muscular Atrophy written by Charlotte J Sumner and published by Academic Press. This book was released on 2016-10-24 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spinal Muscular Atrophy: Disease Mechanisms and Therapy provides the latest information on a condition that is characterized by motoneuron loss and muscle atrophy, and is the leading genetic cause of infant mortality. Since the identification of the gene responsible for SMA in 1995, there have been important advances in the basic understanding of disease mechanisms, and in therapeutic development. This book provides a comprehensive accounting of recent advances in basic and clinical research that covers SMA clinical features and standards of care, multifaceted aspects of SMN protein functions and SMA disease pathology, various animal models, and biomarkers, as well as current therapeutic development. This title is ideal for graduate students/postdocs and principal investigators who are already in the SMA field and need to keep updated on recent findings and approaches, and for those who are new to, or would like to join, the field. Likewise, users will find an excellent source of reading for biotech/pharma scientists, clinical researchers, and practitioners, regulators, and patients and their advocacy organizations. Furthermore, this book is a handy reference for researchers and clinicians who may want to apply the research strategies and therapeutic approaches in SMA to other rare diseases. - Provides comprehensive, up-to-date reviews by leading investigators on diverse topics of SMA, including clinical features and patient care, SMN genetics and protein functions, animal models, disease pathology and mechanisms, biomarkers, current therapeutic development, and the role of non-profit organizations in therapeutic development - Written to bridge multiple disciplines and promote better communications among basic scientists, clinical researchers, and health care providers on the latest developments in SMA - Includes outstanding questions and perspectives for future investigations and key references for additional detailed study

Ruminant Physiology

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Author :
Publisher : CABI
ISBN 13 : 9780851997124
Total Pages : 492 pages
Book Rating : 4.9/5 (971 download)

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Book Synopsis Ruminant Physiology by : Pierre Cronjé

Download or read book Ruminant Physiology written by Pierre Cronjé and published by CABI. This book was released on 2000 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: The International Symposium on Ruminant Physiology (ISRP) is the premier forum for presentation and discussion of advances in knowledge of the physiology of ruminant animals. This book brings together edited versions of the keynote review papers presented at the symposium.

Insulin-Like Growth Factors in Development, Cancers and Aging

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Author :
Publisher : MDPI
ISBN 13 : 3036507701
Total Pages : 196 pages
Book Rating : 4.0/5 (365 download)

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Book Synopsis Insulin-Like Growth Factors in Development, Cancers and Aging by : Haim Werner

Download or read book Insulin-Like Growth Factors in Development, Cancers and Aging written by Haim Werner and published by MDPI. This book was released on 2021-08-30 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Special Issue of Cells on “Insulin-Like Growth Factors in Development, Cancers and Aging” provides a collection of modern articles dealing with the role of insulin-like growth factors (IGF1) in cancer biology, aging and development. Featured articles explore basic and clinical aspects of the IGF1 system, including post-genomic analyses as well as novel approaches to target the IGF1 receptor (IGF1R) in oncology.

Cytokine Inhibitors

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Publisher : CRC Press
ISBN 13 : 9780203904244
Total Pages : 392 pages
Book Rating : 4.9/5 (42 download)

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Book Synopsis Cytokine Inhibitors by : Gennaro Ciliberto

Download or read book Cytokine Inhibitors written by Gennaro Ciliberto and published by CRC Press. This book was released on 2000-11-14 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Compiling an up-to-date and detailed survey of the role cytokines play in cell-to-cell communication, development, and differentiation, this comprehensive reference highlights the medical advantages of cytokine inhibition and pursues novel methods of discovery for more potent and specific blocking agents. Investigates the pathogenic role of

Autophagy and Cancer

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Publisher : Springer Science & Business Media
ISBN 13 : 1461465613
Total Pages : 267 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Autophagy and Cancer by : Hong-Gang Wang

Download or read book Autophagy and Cancer written by Hong-Gang Wang and published by Springer Science & Business Media. This book was released on 2013-03-30 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the explosion of information on autophagy in cancer, this is an opportune time to speed the efforts to translate our current knowledge about autophagy regulation into better understanding of its role in cancer. This book will cover the latest advances in this area from the basics, such as the molecular machinery for autophagy induction and regulation, up to the current areas of interest such as modulation of autophagy and drug discovery for cancer prevention and treatment. The text will include an explanation on how autophagy can function in both oncogenesis and tumor suppression and a description of its function in tumor development and tumor suppression through its roles in cell survival, cell death, cell growth as well as its influences on inflammation, immunity, DNA damage, oxidative stress, tumor microenvironment, etc. The remaining chapters will cover topics on autophagy and cancer therapy. These pages will serve as a description on how the pro-survival function of autophagy may help cancer cells resist chemotherapy and radiation treatment as well as how the pro-death functions of autophagy may enhance cell death in response to cancer therapy, and how to target autophagy for cancer prevention and therapy − what to target and how to target it. ​

Biochemistry of Exercise X

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Author :
Publisher : Human Kinetics
ISBN 13 : 9780880117586
Total Pages : 356 pages
Book Rating : 4.1/5 (175 download)

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Book Synopsis Biochemistry of Exercise X by : Mark Hargreaves

Download or read book Biochemistry of Exercise X written by Mark Hargreaves and published by Human Kinetics. This book was released on 1999 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drawing from the work of leading researchers in 26 countries, Biochemistry of Exercise X delivers an up-to-date, wide-ranging examination of membranes, muscles, and exercise. Experts in the field of biochemistry offer the latest research findings on topics such as signaling, excitation-contraction, metabolism, and adaption. The book features the proceedings of the prestigious Tenth International Conference on Biochemistry of Exercise held in Sydney, Australia, by the Research Group on Biochemistry of Exercise (ICSSPE) July 15-19, 1997. Featuring 48 illustrations and 9 tables, Biochemistry of Exercise X thoroughly examines recent findings on the basic mechanisms shaping exercise biochemistry and details their applications to specific areas in the field.

Immune Function in Sport and Exercise

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 0443101183
Total Pages : 338 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Immune Function in Sport and Exercise by : Michael Gleeson

Download or read book Immune Function in Sport and Exercise written by Michael Gleeson and published by Elsevier Health Sciences. This book was released on 2006-01-01 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title is directed primarily towards health care professionals outside of the United States. Designed to help readers understand and evaluate the relationship between exercise, immune function and infection risk, this book presents evidence for the "J-shaped" relationship between exercise load and infection risk. It also describes the components of the human immune system and key functions that protect the body from disease, the impact of acute and chronic psychological stress on immune function, and practical guidelines for minimizing the risk of immunodepression and infection in athletes. Further chapters explore different ways of measuring immune function, as well as the effects of heavy training on innate and specific (acquired) immunity, exercise in environmental extremes, and nutrition. Connections between exercise, infection risk, and immune function in special populations (elderly, obese, diabetic and HIV patients) are also addressed. Authored by a team of highly experienced experts. The "J-shaped" relationship between exercise load and infection risk is described, backed by current research and evidence. Components of the immune system and normal immune function are explained in detail, as well as methods for measuring immune function. The impact of acute and chronic psychological stress on immune function is presented, along with suggestions for minimizing the risk of immunodepression and infection in athletes. The effects of heavy training, exercise in environmental extremes, and nutrition are discussed with regard to their impact on innate and specific (acquired) immunity. Immune function in special populations (elderly, obese, diabetic and HIV patients) is also addressed, exploring links between exercise and infection risk in these groups. Evidence-based coverage includes a list of references in each chapter, as well as suggestions for further reading that direct readers to important texts and review articles. Information is presented in an easily accessible format, following a logical progression of material. LEach chapter begins with a list of learning objectives and ends with a list of key points to reinforce learning. A glossary at the end of the book defines all key terms and abbreviations.

Pathology of Skeletal Muscle

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Author :
Publisher : New York : Churchill Livingstone
ISBN 13 :
Total Pages : 812 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Pathology of Skeletal Muscle by : Stirling Carpenter

Download or read book Pathology of Skeletal Muscle written by Stirling Carpenter and published by New York : Churchill Livingstone. This book was released on 1984 with total page 812 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book has been described as the bible of muscle disease, from both a scientific and a clinical point of view. It is a comprehensive work that explains and illustrates in detail all pathological reactions of skeletal muscles that occur in human disease. The microscopic changes are illustrated by histochemistry, immunocytochemistry, resin histology, and electron microscopy. The pathological findings are correlated with the clinical picture whenever possible. The interpretation of the findings is scientifically based. To facilitate this process, the fundamentals of normal histology and biology of the muscle cell are also covered.The book has been thoroughly revised and expanded for this Second Edition to provide up-to-date coverage of the relevant molecular biology and molecular genetics, as well as extensive references. It has been well organized and richly illustrated by the authors, who have been at the forefront of muscle pathology and neuromuscular research for 35 years. This practical reference work is intended for neuropathologists, neurologists, and general pathologists who look at muscle biopsies. It will also serve as an introduction to muscle disease for neurology and pathology residents.

Lipid Modification of Proteins

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Author :
Publisher : Oxford University Press, USA
ISBN 13 :
Total Pages : 318 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Lipid Modification of Proteins by : N. M. Hooper

Download or read book Lipid Modification of Proteins written by N. M. Hooper and published by Oxford University Press, USA. This book was released on 1992 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lipid Modification of Proteins: A Practical Approach is a unique guide to the latest methods is use, written by the acknowledged experts in the field. Detailed protocols are provided for all the key techniques, and the relevant background material is included. This book is an essential manual for a wide range of scientists studying the modification of protein by lipids, including membrane and protein biochemists, cell biologists, immunologists, bacteriologists, parasitologists, and virologists.