Lipid Mediators And Their Metabolism In The Brain

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Lipid Mediators and Their Metabolism in the Brain

Author : Akhlaq A. Farooqui
Publisher : Springer Science & Business Media
ISBN 13 : 144199940X
Total Pages : 344 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Lipid Mediators and Their Metabolism in the Brain by : Akhlaq A. Farooqui

Download or read book Lipid Mediators and Their Metabolism in the Brain written by Akhlaq A. Farooqui and published by Springer Science & Business Media. This book was released on 2011-08-12 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lipid Mediators and Their Metabolism in the Brain presents readers with cutting edge and comprehensive information not only on the synthesis and degradation of glycerophospholipid-, sphingolipid-, and cholesterol-derived lipid mediators, but also their involvement in neurological disorders. It is hoped that this monograph will be useful not only to postgraduate student and their teachers, but also to research scientists and physicians, who are curious about the generation and roles of lipid mediators in the brain.

Metabolism and Functions of Bioactive Ether Lipids in the Brain

Author : Akhlaq A. Farooqui
Publisher : Springer Science & Business Media
ISBN 13 : 0387774017
Total Pages : 269 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Metabolism and Functions of Bioactive Ether Lipids in the Brain by : Akhlaq A. Farooqui

Download or read book Metabolism and Functions of Bioactive Ether Lipids in the Brain written by Akhlaq A. Farooqui and published by Springer Science & Business Media. This book was released on 2008-04-13 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: Information on bioactive ether lipids and their involvement in neurological disorders is currently scattered throughout the literature. This book provides readers with a comprehensive description of metabolism of bioactive ether lipids in the brain, activities of enzymes involved in their metabolism, and their involvement in neurological disorders. It is the first book to describe the involvement of these lipids with abnormal signal transduction processes in neurological disorders.

Hot Topics in Neural Membrane Lipidology

Author : Akhlaq A. Farooqui
Publisher : Springer Science & Business Media
ISBN 13 : 0387096930
Total Pages : 423 pages
Book Rating : 4.3/5 (87 download)

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Book Synopsis Hot Topics in Neural Membrane Lipidology by : Akhlaq A. Farooqui

Download or read book Hot Topics in Neural Membrane Lipidology written by Akhlaq A. Farooqui and published by Springer Science & Business Media. This book was released on 2009-04-05 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glycerophospholipid and sphingolipid-derived lipid mediators facilitate the transfer of messages not only from one cell to another but also from one subcellular organelle to another. These molecules are not only components of neural membranes but also storage depots for lipid mediators. Information on the generation and involvement of lipid mediators in neurological disorders is scattered throughout the literature in the form of original papers and reviews. This book will provide readers with a comprehensive description of glycerophospholipid, sphingolipid and cholesterol-derived lipid mediators and their involvement in neurological disorders.

Hot Topics in Neural Membrane Lipidology

Author : Akhlaq A. Farooqui
Publisher : Springer
ISBN 13 : 9780387561431
Total Pages : 0 pages
Book Rating : 4.5/5 (614 download)

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Book Synopsis Hot Topics in Neural Membrane Lipidology by : Akhlaq A. Farooqui

Download or read book Hot Topics in Neural Membrane Lipidology written by Akhlaq A. Farooqui and published by Springer. This book was released on 2008-11-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glycerophospholipid and sphingolipid-derived lipid mediators facilitate the transfer of messages not only from one cell to another but also from one subcellular organelle to another. These molecules are not only components of neural membranes but also storage depots for lipid mediators. Information on the generation and involvement of lipid mediators in neurological disorders is scattered throughout the literature in the form of original papers and reviews. This book will provide readers with a comprehensive description of glycerophospholipid, sphingolipid and cholesterol-derived lipid mediators and their involvement in neurological disorders.

Lipids in the Brain

Author : Elisabetta Albi
Publisher : Frontiers Media SA
ISBN 13 : 288963986X
Total Pages : 109 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Lipids in the Brain by : Elisabetta Albi

Download or read book Lipids in the Brain written by Elisabetta Albi and published by Frontiers Media SA. This book was released on 2020-09-03 with total page 109 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Polyunsaturated Fatty Acid Metabolism

Author : Graham C. Burdge
Publisher : Elsevier
ISBN 13 : 012811231X
Total Pages : 252 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Polyunsaturated Fatty Acid Metabolism by : Graham C. Burdge

Download or read book Polyunsaturated Fatty Acid Metabolism written by Graham C. Burdge and published by Elsevier. This book was released on 2018-05-04 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polyunsaturated Fatty Acid Metabolism explores a number of major roles of PUFA in the body, including its role as a component of cell membranes and how it provides substrates for the synthesis of lipid second messengers. Recent studies are unraveling the effect of interactions between diet and endocrine factors and genetic and epigenetic variation on the regulation of PUFA biosynthesis in animals. Together, these recent findings provide novel insights into the impact of differences in PUFA supply on health. This book captures these findings in a manner that marks the state-of-the-art, placing them in the wider context of PUFA metabolism and nutritional science. Users will find a comprehensive discussion on the topic that presents the contributions of leading researchers who combine their knowledge to create a cohesive academic resource for researchers, those involved in production, and health policymakers. Provides a comprehensive view of polyunsaturated fatty acid metabolism Describes underlying metabolism on lipids that include polyunsaturated fatty acids Includes discussions on recent findings on the genetic and epigenetic regulation of polyunsaturated fatty acid metabolism

Bioactive Lipid Mediators

Author : Takehiko Yokomizo
Publisher : Springer
ISBN 13 : 4431556699
Total Pages : 426 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis Bioactive Lipid Mediators by : Takehiko Yokomizo

Download or read book Bioactive Lipid Mediators written by Takehiko Yokomizo and published by Springer. This book was released on 2015-10-27 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes the most recent progress in the studies of lipid mediators from the molecular to clinical level and introduces newly created tools for analysis including imaging mass spectrometry. Comprising 29 chapters divided into four major parts, the book describes the molecular natures of enzymes, transporters, and receptors for lipid mediators (Part I), the function of lipid mediators in Drosophila and Zebrafish (Part II), the relationships between lipid mediators and various diseases (Part III), and detailed procedures of extraction, preparation, and quantification of lipid mediators (Part IV). Research on lipid mediators initially started with analysis of the action of aspirin, and subsequent biochemical experiments identified many enzymes and receptors responsible for the biosynthesis and signal transduction of individual lipid mediators. Through the phenotypic analyses of transgenic and knockout mice, it has been shown that the dysregulation of some lipid mediators causes inflammatory, immune, or oncogenic disorders. Lipid mediators have attracted increased attention because their structures are conserved among different species, and their biosynthetic and signaling pathways have been deciphered at the molecular level. Many drugs that target lipid mediators are already being used in hospitals, and this book suggests further possibilities for development of a wide variety of such drugs. Very recently, highly sensitive mass spectrometry has begun to be used to identify novel lipid mediators that are present only in trace amounts in tissues but with robust biological activity. Written by international experts, this book provides readers a comprehensive view of lipid mediators and related topics and helps in the process of determining research targets for the near future.

Brain Development

Author : Jacqueline Jumpsen
Publisher : The American Oil Chemists Society
ISBN 13 : 9780935315653
Total Pages : 140 pages
Book Rating : 4.3/5 (156 download)

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Book Synopsis Brain Development by : Jacqueline Jumpsen

Download or read book Brain Development written by Jacqueline Jumpsen and published by The American Oil Chemists Society. This book was released on 1995-08-30 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book's objective is to provide a focused overview (morphological, biochemical, and functional) of brain development, to exemplify the role of lipids in the important developmental events, and to develop the concepts explaining why physiological changes in brain lipid composition potentially alter these events.

The Resolution of Inflammation

Author : Adriano Rossi
Publisher : Springer Science & Business Media
ISBN 13 : 376437506X
Total Pages : 246 pages
Book Rating : 4.7/5 (643 download)

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Book Synopsis The Resolution of Inflammation by : Adriano Rossi

Download or read book The Resolution of Inflammation written by Adriano Rossi and published by Springer Science & Business Media. This book was released on 2008-03-17 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides readers with an up-to-date and comprehensive view on the resolution of inflammation and on new developments in this area, including pro-resolution mediators, apoptosis, macrophage clearance of apoptotic cells, possible novel drug developments.

Beneficial Effects of Fish Oil on Human Brain

Author : Akhlaq A. Farooqui
Publisher : Springer
ISBN 13 : 9781489983930
Total Pages : 0 pages
Book Rating : 4.9/5 (839 download)

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Book Synopsis Beneficial Effects of Fish Oil on Human Brain by : Akhlaq A. Farooqui

Download or read book Beneficial Effects of Fish Oil on Human Brain written by Akhlaq A. Farooqui and published by Springer. This book was released on 2014-11-26 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is becoming increasingly evident that the deficiency of n-3 fatty acids in diet is not only associated with cardiovascular diseases, but also involved in stroke, epilepsy and other neurological and neurodegenerative diseases, such as Alzheimer disease, Parkinson disease, and peroxisomal diseases. In his newest book, Beneficial Effects of Fish Oil on Human Brain, Dr. Akhlaq A. Farooqui expands on the status and therapeutic importance of n-3 fatty acids (major components of fish oil) and their mediators in normal brain and those with neurodegenerative and neuropsychiatric diseases. Farooqui presents the benefits of n-3 fatty acids on Western diet, which is enriched in n-6 fatty acids (major components of vegetable oil) and may promote the above neurological disorders. The book will present readers with cutting edge and comprehensive information on metabolism and roles of neural membrane n-3 fatty acids.

Emerging Role of Lipids in Metabolism and Disease

Author : Marco Segatto
Publisher : MDPI
ISBN 13 : 3039437011
Total Pages : 308 pages
Book Rating : 4.0/5 (394 download)

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Book Synopsis Emerging Role of Lipids in Metabolism and Disease by : Marco Segatto

Download or read book Emerging Role of Lipids in Metabolism and Disease written by Marco Segatto and published by MDPI. This book was released on 2021-04-01 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Even though initially considered as a passive means for storing energy, lipids are now regarded as multifaceted molecules with crucial structural and functional activities. For instance, some of them play essential roles as key components of cell membranes whereas others act as signaling molecules in the regulation of cell homeostasis. In recent years, lipid research has attracted increasing interest because of the involvement of this class of compounds in human health. Indeed, a plethora of pathological conditions are characterized by alterations in lipid metabolism, such as cardiovascular diseases and brain disorders. This Special Issue is a collection of papers from different experts in lipid research, with the aim of providing new insights into the physiopathological involvement of lipids and their impact on human health. This collection also demonstrates the usefulness of interdisciplinary approaches in the development of novel methods to study and manipulate lipid metabolism, which may represent an attractive target for designing effective therapeutic strategies to counteract numerous pathologies.

Omega Fatty Acids in Brain and Neurological Health

Author : Ronald Ross Watson
Publisher : Academic Press
ISBN 13 : 0128152397
Total Pages : 518 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Omega Fatty Acids in Brain and Neurological Health by : Ronald Ross Watson

Download or read book Omega Fatty Acids in Brain and Neurological Health written by Ronald Ross Watson and published by Academic Press. This book was released on 2019-06-12 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research has clearly established a link between omega fatty acids and general health, particularly cardiovascular health. Omega Fatty Acids in Brain and Neurological Health, Second Edition, illustrates the importance of omega-3 fatty acids in longevity, cognitive impairment and structure and function of the brain's neurons and also the adverse effects of omega-6 fatty acids on neurological function. This book encompasses some of the most recent research on the links between omega fatty acids and the developing brain, aging, dementia, Alzheimer's disease and multiple sclerosis, including the role of omega-3 fatty acid supplements on hippocampal neurogenesis, substantia nigra modulation, migraine headaches, the developing brain in animals, sleep and neurodegenerative diseases. This completely updated second edition focuses on the counterbalancing dietary and tissue omega-6 fatty acids as well as it studies the effects in pregnancy and early infancy, animal model studies and autoimmune neurological diseases. Provides a comprehensive introduction to omega-3 and omega-6 fatty acids in neurological health and directions for future research Features novel focus on the adverse effects of omega-6 fatty acids on neurological function and the counterbalancing of dietary and tissue omega-6 Illustrates the importance of omega-3 fatty acids in longevity and cognitive impairment Features new chapters on early effects in pregnancy and early infancy, animal model studies and autoimmune neurological diseases Discusses links between omega fatty acids and the developing brain, aging, dementia, Alzheimer's disease and multiple sclerosis, including the role of omega-3 fatty acid supplements

Neuroinflammation, Resolution, and Neuroprotection in the Brain

Author : Akhlaq A. Farooqui
Publisher : Academic Press
ISBN 13 : 032388461X
Total Pages : 334 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Neuroinflammation, Resolution, and Neuroprotection in the Brain by : Akhlaq A. Farooqui

Download or read book Neuroinflammation, Resolution, and Neuroprotection in the Brain written by Akhlaq A. Farooqui and published by Academic Press. This book was released on 2021-09-15 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroinflammation, Resolution, and Neuroprotection in the Brain discusses the molecular aspects of neuroinflammation in neurological disorders. The book examines the effect of diet and exercise on neuroinflammatory diseases. Chapters focus on bioactive lipids, cytokines and chemokines, as well as the involvement of neuroinflammation, resolution and neuroprotection in neurotraumatic diseases, neurodegenerative diseases and neuropsychiatric diseases. The comprehensive information in this monograph will help readers understand molecular cross-talk among mediators of phospholipid, sphingolipid and cholesterol metabolism. The book's goal is to jumpstart more studies on molecular mechanisms and the therapeutic aspects of neurological disorders in human subjects. Discusses the molecular aspects of neuroinflammation, resolution and neuroprotection Examines the role of diet and exercise on neuroinflammatory diseases Provides cutting-edge research on signal transduction processes Explores the treatment of neurological disorders caused by neuroinflammation

Ischemic and Traumatic Brain and Spinal Cord Injuries

Author : Akhlaq A. Farooqui
Publisher : Academic Press
ISBN 13 : 0128135972
Total Pages : 484 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Ischemic and Traumatic Brain and Spinal Cord Injuries by : Akhlaq A. Farooqui

Download or read book Ischemic and Traumatic Brain and Spinal Cord Injuries written by Akhlaq A. Farooqui and published by Academic Press. This book was released on 2018-03-21 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ischemic and Traumatic Brain and Spinal Cord Injuries: Mechanisms and Potential Therapies presents readers with comprehensive and cutting-edge information on molecular mechanisms, including the signal transduction processes associated with neurodegeneration and neuroprotection in ischemic, spinal cord, severe and mild brain injuries. The book also covers the molecular mechanisms of drugs used for the treatment of neurotraumatic disease. Chapters are organized by molecular aspects and neuroprotective strategies by disease, including ischemic injury, spinal cord injury, traumatic brain injury, and chronic traumatic encephalopathy. The book integrates and consolidates knowledge on neurotraumatic diseases, with the hope of bringing forth more dramatic advances and developments, not only on molecular mechanisms, but also on the causes of, and treatments for, neurotraumatic diseases. Offers a clearly written, logically organized, comprehensive overview on the molecular aspects of risk factors, pathogenesis, biomarkers, and therapeutic strategies for ischemic, spinal cord, severe and mild brain injuries Provides cutting-edge research information on the signal transduction processes associated with neurodegeneration and neuroprotection in ischemic, spinal cord, severe and mild brain injuries Presents chapters that are organized by molecular aspects and neuroprotective strategies by disease, including ischemic injury, spinal cord injury, traumatic brain injury, and chronic traumatic encephalopathy

Neurochemical Aspects of Alzheimer's Disease

Author : Akhlaq A. Farooqui
Publisher : Academic Press
ISBN 13 : 0128099380
Total Pages : 414 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Neurochemical Aspects of Alzheimer's Disease by : Akhlaq A. Farooqui

Download or read book Neurochemical Aspects of Alzheimer's Disease written by Akhlaq A. Farooqui and published by Academic Press. This book was released on 2017-05-25 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurochemical Aspects of Alzheimer's Disease provides a comprehensive overview of molecular aspects of risk factors, pathogenesis, biomarkers, and therapeutic strategies. The book focuses on molecular mechanisms and signal transduction processes associated with the pathogenesis, biomarkers, and therapeutic strategies of AD. The comprehensive and cutting edge information in this monograph may not only help in early detection of AD, but also promote discovery of new drugs to treat this chronic disease. Chapters discuss involvement of neural membrane phospholipids, sphingolipids, and cholesterol-derived lipid mediators, abnormal APP processing, and nucleic acid damage, risk factors, biomarker, and therapeutic strategies of Alzheimer's disease. This book is written for neurologists, neuroscientists, neurochemists, neuropharmacologists, and clinicianswho are interested in molecular mechanisms associated with the pathogenesis of age-related neurological disorders. Provides a comprehensive overview of molecular aspects of risk factors, pathogenesis, biomarkers, and therapeutic strategies for Alzheimer's disease Written for researchers, clinicians, and advanced graduate students in neurology, neuroscience, neurochemistry, and neuropharmacology Acts as the first book to provide a comprehensive description of the signal transduction processes associated with pathogenesis of Alzheimer's disease

High Calorie Diet and the Human Brain

Author : Akhlaq A. Farooqui
Publisher : Springer
ISBN 13 : 3319152548
Total Pages : 325 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis High Calorie Diet and the Human Brain by : Akhlaq A. Farooqui

Download or read book High Calorie Diet and the Human Brain written by Akhlaq A. Farooqui and published by Springer. This book was released on 2015-03-25 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this monograph is to present readers with a comprehensive and cutting edge description of neurochemical effects of diet (beneficial and harmful effects) in normal human brain and to discuss how present day diet promotes pathogenesis of stroke, AD, PD, and depression in a manner that is useful not only to students and teachers but also to researchers, dietitians, nutritionists and physicians. A diet in sufficient amount and appropriate macronutrients is essential for optimal health of human body tissues. In brain, over-nutrition, particularly with high-calorie diet, not only alters cellular homeostasis, but also results in changes in the intensity of signal transduction processes in reward centers of the brain resulting in food addiction. Over-nutrition produces detrimental effects on human health in general and brain health in particular because it chronically increases the systemic and brain inflammation and oxidative stress along with induction of insulin resistance and leptin resistance in the brain as well as visceral organs. Onset of chronic inflammation and oxidative stress not only leads to obesity and heart disease, but also promotes type II diabetes and metabolic syndrome, which are risk factors for both acute neural trauma (stroke) and chronic age-related neurodegenerative and neuropsychological disorders, such as Alzheimer disease (AD), Parkinson disease (PD) and depression.

Molecular Mechanisms of Dementia

Author : Akhlaq A. Farooqui
Publisher : Academic Press
ISBN 13 : 0128167319
Total Pages : 386 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Molecular Mechanisms of Dementia by : Akhlaq A. Farooqui

Download or read book Molecular Mechanisms of Dementia written by Akhlaq A. Farooqui and published by Academic Press. This book was released on 2019-04-15 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Considerable progress has been made in neurochemical and therapeutic aspects of dementia research in recent years. Molecular and Therapeutic Aspects of Dementia presents readers with comprehensive and cutting-edge information on the neurochemical mechanisms of various types of dementias. It provides a clearly written and logically organized and comprehensive overview of molecular aspects of risk factors, symptoms, pathogenesis, biomarkers, and therapeutic strategies for various types of dementia. This book is written for the international audience of neurochemists, neuroscientists, neurologists, neuropharmacologists, and clinicians. The hope is that this discussion will not only integrate and consolidate knowledge in this field, but will jumpstart more studies on molecular mechanisms and therapeutic aspects of dementia. The comprehensive information in this monograph may not only help in early detection of various types of dementia and dementia linked neurological disorders, but also promote discovery of new drugs, which may block or delay the onset of dementia in elderly patients. Understanding the course of dementia is important not only for patients, caregivers, and health professionals, but also for health policy-makers, who have to plan for national resources needed in the management of an increasing number of dementia cases. Provides a comprehensive overview of molecular aspects of risk factors, symptoms, pathogenesis, biomarkers, and therapeutic strategies for various types of dementia Summarizes cutting edge research information on signal transduction processes associated with neurochemistry of dementia Discusses the synthesis, metabolism, and role of lipid mediators in dementia