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Author : Joaquin Teixidó
Publisher : Frontiers Media SA
ISBN 13 : 2889632962
Total Pages : 153 pages
Book Rating : 4.8/5 (896 download)
Download or read book Leukocyte Trafficking in Homeostasis and Disease written by Joaquin Teixidó and published by Frontiers Media SA. This book was released on 2019-12-30 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Raffaele Badolato
Publisher : Birkhäuser
ISBN 13 : 9783764390853
Total Pages : 253 pages
Book Rating : 4.3/5 (98 download)
Download or read book Lymphocyte Trafficking in Health and Disease written by Raffaele Badolato and published by Birkhäuser. This book was released on 2009-09-03 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with the description of the role of chemokines in immune response and underlines potential targets of therapeutical intervention. It offers a series of international contributions of the most challenging aspects of lymphocyte migration in homeostasis and in disease, and has a special focus on diseases and targets of therapeutical intervention. The book will interest researchers and clinicians from inflammation research.
Author : Raffaele Badolato
Publisher : Birkhäuser
ISBN 13 : 9783764373085
Total Pages : 253 pages
Book Rating : 4.3/5 (73 download)
Download or read book Lymphocyte Trafficking in Health and Disease written by Raffaele Badolato and published by Birkhäuser. This book was released on 2006-07-18 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with the description of the role of chemokines in immune response and underlines potential targets of therapeutical intervention. It offers a series of international contributions of the most challenging aspects of lymphocyte migration in homeostasis and in disease, and has a special focus on diseases and targets of therapeutical intervention. The book will interest researchers and clinicians from inflammation research.
Author : Raffaele Badolato
Publisher : Springer Science & Business Media
ISBN 13 : 376437442X
Total Pages : 249 pages
Book Rating : 4.7/5 (643 download)
Download or read book Lymphocyte Trafficking in Health and Disease written by Raffaele Badolato and published by Springer Science & Business Media. This book was released on 2006-09-05 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with the description of the role of chemokines in immune response and underlines potential targets of therapeutical intervention. It offers a series of international contributions of the most challenging aspects of lymphocyte migration in homeostasis and in disease, and has a special focus on diseases and targets of therapeutical intervention. The book will interest researchers and clinicians from inflammation research.
Author : Klaus Ley
Publisher : Frontiers Media SA
ISBN 13 : 2889194302
Total Pages : 109 pages
Book Rating : 4.8/5 (891 download)
Download or read book Arrest chemokines written by Klaus Ley and published by Frontiers Media SA. This book was released on 2015-05-20 with total page 109 pages. Available in PDF, EPUB and Kindle. Book excerpt: Arrest chemokines are a small group of chemokines that promote leukocyte arrest from rolling by triggering rapid integrin activation. Arrest chemokines have been described for neutrophils, monocytes, eosinophils, naïve lymphocytes and effector memory T cells. Most arrest chemokines are immobilized on the endothelial surface by binding to heparin sulfate proteoglycans. Whether soluble chemokines can promote integrin activation and arrest is controversial (Alon-Gerszten). Many aspects of the signaling pathway from the GPCR chemokine receptor to integrin activation are the subject of active investigation. Leukocyte adhesion deficiency III is a human disease in which chemokine-triggered integrin activation is defective because of a mutation in the cytoskeletal protein kindlin-3. About 10 different such mutations have been described. The defects seen in patients with LAD-III elucidate the importance of rapid integrin activation for host defense in humans. We welcome reports that help clarifying this crucial first step in the process of leukocyte transendothelial migration.
Author : Koichi Ikuta
Publisher : Frontiers Media SA
ISBN 13 : 2889664325
Total Pages : 105 pages
Book Rating : 4.8/5 (896 download)
Download or read book Circadian Control of Immunity written by Koichi Ikuta and published by Frontiers Media SA. This book was released on 2021-02-03 with total page 105 pages. Available in PDF, EPUB and Kindle. Book excerpt: We acknowledge the initiation and support of this Research Topic by the International Union of Immunological Societies (IUIS). We hereby state publicly that the IUIS has had no editorial input in articles included in this Research Topic, thus ensuring that all aspects of this Research Topic are evaluated objectively, unbiased by any specific policy or opinion of the IUIS.
Author : Alf Hamann
Publisher : John Wiley & Sons
ISBN 13 : 3527607013
Total Pages : 557 pages
Book Rating : 4.5/5 (276 download)
Download or read book Leukocyte Trafficking written by Alf Hamann and published by John Wiley & Sons. This book was released on 2006-05-12 with total page 557 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by known specialists in the field, this is a comprehensive and timely overview of a central and expanding topic. Simultaneously an introduction and a description of the latest concepts, findings and methods, the handbook provides basic knowledge on technical issues required for those intending to research in the field. It covers the functional role of involved molecules and the cellular mechanisms, and addresses selected examples for their possible application in therapy -- bridging the gap between trafficking mechanisms and novel therapeutic strategies. In addition, it includes selection of proven and timesaving methods for studying cell trafficking in vitro and in vivo. The accompanying CD-ROM makes leukocyte migration videos available to a broad audience for the first time.
Author : Patricia Lalor
Publisher : Frontiers Media SA
ISBN 13 : 2889747948
Total Pages : 174 pages
Book Rating : 4.8/5 (897 download)
Download or read book Roles of Liver Sinusoidal Endothelial Cells in Liver Homeostasis and Disease written by Patricia Lalor and published by Frontiers Media SA. This book was released on 2022-03-30 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kenneth Murphy
Publisher : Garland Science
ISBN 13 : 9780815344575
Total Pages : pages
Book Rating : 4.3/5 (445 download)
Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Author : Michel Félétou
Publisher : Morgan & Claypool Publishers
ISBN 13 : 1615041230
Total Pages : 309 pages
Book Rating : 4.6/5 (15 download)
Download or read book The Endothelium written by Michel Félétou and published by Morgan & Claypool Publishers. This book was released on 2011 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in direct contact with the blood/lymph and the circulating cells. The endothelium is a major player in the control of blood fluidity, platelet aggregation and vascular tone, a major actor in the regulation of immunology, inflammation and angiogenesis, and an important metabolizing and an endocrine organ. Endothelial cells controls vascular tone, and thereby blood flow, by synthesizing and releasing relaxing and contracting factors such as nitric oxide, metabolites of arachidonic acid via the cyclooxygenases, lipoxygenases and cytochrome P450 pathways, various peptides (endothelin, urotensin, CNP, adrenomedullin, etc.), adenosine, purines, reactive oxygen species and so on. Additionally, endothelial ectoenzymes are required steps in the generation of vasoactive hormones such as angiotensin II. An endothelial dysfunction linked to an imbalance in the synthesis and/or the release of these various endothelial factors may explain the initiation of cardiovascular pathologies (from hypertension to atherosclerosis) or their development and perpetuation. Table of Contents: Introduction / Multiple Functions of the Endothelial Cells / Calcium Signaling in Vascular Cells and Cell-to-Cell Communications / Endothelium-Dependent Regulation of Vascular Tone / Conclusion / References
Author : Ajit Varki
Publisher : CSHL Press
ISBN 13 : 9780879696818
Total Pages : 694 pages
Book Rating : 4.6/5 (968 download)
Download or read book Essentials of Glycobiology written by Ajit Varki and published by CSHL Press. This book was released on 1999 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.
Author : Gyorgy Hasko
Publisher : CRC Press
ISBN 13 : 1420005774
Total Pages : 377 pages
Book Rating : 4.4/5 (2 download)
Download or read book Adenosine Receptors written by Gyorgy Hasko and published by CRC Press. This book was released on 2006-07-20 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: After a century of research, several lines of evidence now indicate that the ability of adenosine to directly control inflammatory cells has a major impact on the functions of the inflammatory and immune systems. Consequently, many promising therapeutic approaches are beginning to emerge that focus on the modulation of adenosine, including the deve
Author : Kaushik Parthasarathi
Publisher : Springer
ISBN 13 : 9783319684826
Total Pages : 86 pages
Book Rating : 4.6/5 (848 download)
Download or read book Molecular and Functional Insights Into the Pulmonary Vasculature written by Kaushik Parthasarathi and published by Springer. This book was released on 2018-01-09 with total page 86 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive review of the structure, function and pathophysiology of the pulmonary vasculature. Emerging evidence reveals the multifaceted roles played by the pulmonary vasculature. To reflect those roles, the individual chapters address topics ranging from pulmonary blood vessel development to vascular endothelial apoptosis, and delve deeply into our current understanding of various aspects of the pulmonary vasculature.
Author : Helen Michelle McGettrick
Publisher : Frontiers Media SA
ISBN 13 : 2889742857
Total Pages : 172 pages
Book Rating : 4.8/5 (897 download)
Download or read book Targeting Leukocyte Trafficking: Insights and Future Directions written by Helen Michelle McGettrick and published by Frontiers Media SA. This book was released on 2022-02-04 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Zhichao Fan
Publisher : Frontiers Media SA
ISBN 13 : 2889669750
Total Pages : 443 pages
Book Rating : 4.8/5 (896 download)
Download or read book Imaging and Mechanism of Leukocyte Recruitment and Function in Inflammation and Infections written by Zhichao Fan and published by Frontiers Media SA. This book was released on 2021-07-05 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Soichiro Miura
Publisher : Morgan & Claypool Publishers
ISBN 13 : 1615041443
Total Pages : 125 pages
Book Rating : 4.6/5 (15 download)
Download or read book Intestinal Immune System written by Soichiro Miura and published by Morgan & Claypool Publishers. This book was released on 2011 with total page 125 pages. Available in PDF, EPUB and Kindle. Book excerpt: These negative regulatory mechanisms of the intestinal immune system are disturbed in certain disease conditions, causing the immunocompetent cells to respond to food components and commensal bacteria by becoming activated and to overproduce inflammatory cytokines and chemokines. These disease conditions include food allergies, such as celiac disease, and the inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease, although their exact etiological mechanisms remain to be revealed. --Book Jacket.
Author : Yoshiro Maru
Publisher : Springer
ISBN 13 : 4431560246
Total Pages : 505 pages
Book Rating : 4.4/5 (315 download)
Download or read book Inflammation and Metastasis written by Yoshiro Maru and published by Springer. This book was released on 2016-07-25 with total page 505 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the latest information on cancer metastasis from the standpoint of inflammation, especially innate immune reactions caused by endogenous mediators but not exogenous pathogens, with ideas on how to understand the complicated mechanisms of metastasis as well as to interpret therapeutic targets. The book includes the topic of the emerging roles of endogenous TLR4 ligands whose functions are shared intriguingly by metastasis and auto-inflammatory diseases such as rheumatoid arthritis. For example, most cancer therapies established so far are effective initially. However, they eventually face the great obstacles of drug resistance, immune evasion, and metastatic progression. One of the endogenous TLR4 ligands is thought to contribute to all three processes. The most important features of the book are to explain a concept of homeostatic inflammation, disturbance of which in the lungs gives rise to the establishment of a pre-metastatic pulmonary microenvironment based on primary tumor-mediated hijacking of the innate immune defense system against respiratory infection. In addition, structure-based thinking is another important feature of this book. It is proposed that inflammation forms a functional triangle with angiogenesis and coagulation, in the center of which cancer is located. Given the proposal of precision medicine by President Obama in the United States in 2015 and the recent success of immune-modulator-based therapy, this book will appeal to researchers in a variety of fields with the title of the book connecting the worst disease (metastasis) and the most fundamental event (inflammation) that is common to many diseases.
