Toxines et cancer

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Publisher : Lavoisier
ISBN 13 : 2743019530
Total Pages : 333 pages
Book Rating : 4.7/5 (43 download)

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Book Synopsis Toxines et cancer by : GOUDEY-PERRIÈRE Françoise

Download or read book Toxines et cancer written by GOUDEY-PERRIÈRE Françoise and published by Lavoisier. This book was released on 2006-11-26 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: De tout temps, l'homme a eu conscience de l'intérêt thérapeutique des toxines. Certaines toxines végétales depuis longtemps utilisées figurent encore dans la pharmacopée actuelle. Viennent s'y ajouter depuis peu des toxines microbiennes. Cependant le maniement des toxines natives ou à peine modifiées reste délicat tant est faible la marge entre les effets toxiques et l'efficacité thérapeutique. Comment, dans une perspective médicale, canaliser la puissance d'action et l'efficacité d'une toxine ? Connaître sa structure, comprendre son mécanisme d'action n'est pas suffisant : il faut aussi identifier sa cible privilégiée, autrement dit un récepteur cellulaire, faute de quoi l'entreprise apparemment chimérique d'un détournement de sa puissance et de sa spécificité reste aveugle. Ce cap est franchi, depuis un certain nombre d'années, et le développement des recherches sur les toxines axées sur la thérapeutique est devenu foisonnant. Voyez telle ou telle toxine protéique ternaire, avec ses trois domaines, de fixation sur un récepteur membranaire, de translocation qui lui permet de franchir la membrane cellulaire, et d'activité enzymatique qui va alors pouvoir s'exercer dans la cellule. Qu'on parvienne à dissocier chacun de ces trois domaines en leur conservant leurs propriétés, et des possibilités nouvelles d'utilisation thérapeutique vont s'ouvrir, presque à l'infini semble-t-il. Car chacun d'entre eux pourra être couplé à une molécule active bien ciblée, et leur efficacité sera même améliorée pour peu qu'on parvienne à conjuguer leur action. Qu'un récepteur, qu'une molécule, propres au métabolisme ou à la physiologie d'une cellule cancéreuse soient identifiés, et des toxines conjuguées à un ligand de ce récepteur, de cette molécule (ce peut être un anticorps) bloqueront les canaux ioniques ou exerceront leur effet cytolytique sur cette seule cellule, sans nuire aux cellules saines. Nous voilà dégagés de l'utopie, le contenu de cet ouvrage le prouve abondamment. Et même si la concrétisation des promesses reste délicate, le champ d'action est si vaste initialement qu'il ne saurait rester improductif : il ne l'est d'ailleurs déjà plus.

Liquid Sample Introduction in ICP Spectrometry

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Publisher : Elsevier
ISBN 13 : 0080932274
Total Pages : 301 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Liquid Sample Introduction in ICP Spectrometry by : José-Luis Todoli

Download or read book Liquid Sample Introduction in ICP Spectrometry written by José-Luis Todoli and published by Elsevier. This book was released on 2011-04-18 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inductively coupled plasma atomic or mass spectrometry is one of the most common techniques for elemental analysis. Samples to be analyzed are usually in the form of solutions and need to be introduced into the plasma by means of a sample introduction system, so as to obtain a mist of very fine droplets. Because the sample introduction system can be a limiting factor in the analytical performance, it is crucial to optimize its design and its use. It is the purpose of this book to provide fundamental knowledge along with practical instructions to obtain the best out of the technique. - Fundamental as well as practical character - Troubleshooting section - Flow charts with optimum systems to be used for a given application

Mass Spectrometry of Polymers

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Publisher : CRC Press
ISBN 13 : 1420037757
Total Pages : 601 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Mass Spectrometry of Polymers by : Giorgio Montaudo

Download or read book Mass Spectrometry of Polymers written by Giorgio Montaudo and published by CRC Press. This book was released on 2001-10-29 with total page 601 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass Spectrometry (MS) has rapidly become an indispensable tool in polymer analysis, and modern MS today complements in many ways the structural data provided by Nuclear Magnetic Resonance (NMR) and Infrared (IR) methods. Recent advances have sparked a growing interest in this field and established a need for a summary of progress made and results

Proceedings

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Publisher :
ISBN 13 :
Total Pages : 374 pages
Book Rating : 4.0/5 ( download)

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Book Synopsis Proceedings by :

Download or read book Proceedings written by and published by . This book was released on with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt:

UVX 94

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Publisher :
ISBN 13 :
Total Pages : 324 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis UVX 94 by : Jean-Michele Pouvesle

Download or read book UVX 94 written by Jean-Michele Pouvesle and published by . This book was released on 1994 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Commentarium Scientificum Internationale Tractans de Re Spectrochimica

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Publisher :
ISBN 13 :
Total Pages : 1054 pages
Book Rating : 4.:/5 (321 download)

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Book Synopsis Commentarium Scientificum Internationale Tractans de Re Spectrochimica by :

Download or read book Commentarium Scientificum Internationale Tractans de Re Spectrochimica written by and published by . This book was released on 1975 with total page 1054 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Analusis

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Publisher :
ISBN 13 :
Total Pages : 1098 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Analusis by :

Download or read book Analusis written by and published by . This book was released on 1993 with total page 1098 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Physics Briefs

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Publisher :
ISBN 13 :
Total Pages : 1354 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Physics Briefs by :

Download or read book Physics Briefs written by and published by . This book was released on 1988 with total page 1354 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Principles and Practice of Variable Pressure / Environmental Scanning Electron Microscopy (VP-ESEM)

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Publisher : John Wiley & Sons
ISBN 13 : 0470065400
Total Pages : 247 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Principles and Practice of Variable Pressure / Environmental Scanning Electron Microscopy (VP-ESEM) by : Debbie Stokes

Download or read book Principles and Practice of Variable Pressure / Environmental Scanning Electron Microscopy (VP-ESEM) written by Debbie Stokes and published by John Wiley & Sons. This book was released on 2008-12-22 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offers a simple starting point to VPSEM, especially for new users, technicians and students containing clear, concise explanations Crucially, the principles and applications outlined in this book are completely generic: i.e. applicable to all types of VPSEM, irrespective of manufacturer. Information presented will enable reader to turn principles into practice Published in association with the Royal Microscopical Society (RMS) -www.rms.org.uk

Canadian Journal of Physics

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Publisher :
ISBN 13 :
Total Pages : 962 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis Canadian Journal of Physics by :

Download or read book Canadian Journal of Physics written by and published by . This book was released on 1992 with total page 962 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Plasma Polymer Films

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Publisher : World Scientific
ISBN 13 : 1860944671
Total Pages : 391 pages
Book Rating : 4.8/5 (69 download)

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Book Synopsis Plasma Polymer Films by : Hynek Biederman

Download or read book Plasma Polymer Films written by Hynek Biederman and published by World Scientific. This book was released on 2004 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plasma Polymer Films examines the current status of the deposition and characterization of fluorocarbon-, hydrocarbon- and silicon-containing plasma polymer films and nanocomposites, with plasma polymer matrix. It introduces plasma polymerization process diagnostics such as optical emission spectroscopy (OES, AOES), and describes special deposition techniques such as atmospheric pressure glow discharge. Important issues for applications such as degradation and stability are treated in detail, and structural characterization, basic electrical and optical properties and biomedical applications are discussed.

Index bibliographique du vide

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Publisher :
ISBN 13 :
Total Pages : 666 pages
Book Rating : 4.F/5 ( download)

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Download or read book Index bibliographique du vide written by and published by . This book was released on 1967 with total page 666 pages. Available in PDF, EPUB and Kindle. Book excerpt:

ICREEC 2019

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Publisher : Springer Nature
ISBN 13 : 9811554447
Total Pages : 659 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis ICREEC 2019 by : Ahmed Belasri

Download or read book ICREEC 2019 written by Ahmed Belasri and published by Springer Nature. This book was released on 2020-06-10 with total page 659 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights peer reviewed articles from the 1st International Conference on Renewable Energy and Energy Conversion, ICREEC 2019, held at Oran in Algeria. It presents recent advances, brings together researchers and professionals in the area and presents a platform to exchange ideas and establish opportunities for a sustainable future. Topics covered in this proceedings, but not limited to, are photovoltaic systems, bioenergy, laser and plasma technology, fluid and flow for energy, software for energy and impact of energy on the environment.

Principles and Technical Aspects of PCR Amplification

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Publisher : Springer Science & Business Media
ISBN 13 : 1402062419
Total Pages : 333 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Principles and Technical Aspects of PCR Amplification by : Elizabeth van Pelt-Verkuil

Download or read book Principles and Technical Aspects of PCR Amplification written by Elizabeth van Pelt-Verkuil and published by Springer Science & Business Media. This book was released on 2008-03-14 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kary Mullis was awarded a Nobel Prize for inventing the PCR technique more than a decade ago in 1993. Since its "discovery", multiple adaptations and variations of the standard PCR technique have been described. This publication aims to provide the reader with a guide to the standard PCR technique and its many available variants, with particular emphasis being placed on the role of these PCR techniques in the clinical diagnostic laboratory (the central theme of this book).

Cerebrospinal Fluid Biomarkers

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Publisher : Humana
ISBN 13 : 9781071613214
Total Pages : 236 pages
Book Rating : 4.6/5 (132 download)

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Book Synopsis Cerebrospinal Fluid Biomarkers by : Charlotte E. Teunissen

Download or read book Cerebrospinal Fluid Biomarkers written by Charlotte E. Teunissen and published by Humana. This book was released on 2022-05-19 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers the latest methods used in clinical neurochemistry laboratories for both clinical practice and research. Chapters in this book discuss topics such as techniques for cerebrospinal fluid (CSF) collection, pre-analytical processing, and basic CSF analysis; an examination of biomarkers including ELISA and automated immunochemical assays for amyloid and tau markers for Alzheimer’s disease; the analysis of neurofilaments by digital ELISA; and an example of successful novel immunoassay development. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and thorough, Cerebrospinal Fluid Biomarkers is a valuable resource for clinicians and researchers to use in CSF labs and CSF courses.

Advances in Penicillium and Aspergillus Systematics

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Publisher : Springer Science & Business Media
ISBN 13 : 147571856X
Total Pages : 465 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Advances in Penicillium and Aspergillus Systematics by : Robert Samson

Download or read book Advances in Penicillium and Aspergillus Systematics written by Robert Samson and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Indirect Food Additives and Polymers

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Publisher : CRC Press
ISBN 13 : 148229382X
Total Pages : 1321 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Indirect Food Additives and Polymers by : Victor O. Sheftel

Download or read book Indirect Food Additives and Polymers written by Victor O. Sheftel and published by CRC Press. This book was released on 2000-03-30 with total page 1321 pages. Available in PDF, EPUB and Kindle. Book excerpt: More foods are now packaged in containers designed for direct cooking or heating, which encourages movement of substances into the foods. Indirect Food Additives and Polymers: Migration and Toxicology is an impressive review of basic regulatory, toxicological, and other scientific information necessary to identify, characterize, measure, and predict the hazards of nearly 2,000 of the plastic-like materials employed in packaging and identified by the FDA as indirect food additives. It presents the data underlying federal regulations, previously unavailable in one volume, and is a convenient resource for anyone working in the large number of related disciplines.