Cooperation of Liver Cells in Health and Disease

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Publisher : Springer Science & Business Media
ISBN 13 : 3642565530
Total Pages : 154 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Cooperation of Liver Cells in Health and Disease by : Z. Kmiec

Download or read book Cooperation of Liver Cells in Health and Disease written by Z. Kmiec and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is only during the last decade that the functions of sinusoidal endothelial cells, Kupffer cells, hepatic stellate cells, pit cells and other intrahepatic lymphocytes have been better understood. The development of methods for isolation and co-culturing various types of liver cells has established that they communicate and cooperate via secretion of various intercellular mediators. This monograph summarizes multiple data that suggest the important role of cellular cross-talk for the functions of both normal and diseased liver. Special features of the book include concise presentation of the majority of detailed data in 19 tables. Original schemes allow for the clear illustration of complicated intercellular relationships. This is the first ever presentation of the newly emerging field of liver biology, which is important for hepatic function in health and disease and opens new avenues for therapeutic interventions.

Stellate Cells in Health and Disease

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Publisher : Academic Press
ISBN 13 : 0128005440
Total Pages : 335 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Stellate Cells in Health and Disease by : Chandrashekhar Gandhi

Download or read book Stellate Cells in Health and Disease written by Chandrashekhar Gandhi and published by Academic Press. This book was released on 2015-04-10 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stellate Cells in Health and Disease is a comprehensive reference providing the most up-to-date knowledge and perspectives on the function of stellate cells affecting the liver and other organs. The text presents comprehensive coverage of their already established role in hepatic fibrosis along with the newer emerging evidence for stellate cell participation in the liver cell (hepatocyte) survival and regeneration, hepatic immunobiology, transplant tolerance, and liver cancer. Chapters describe both animal and human research and the relevance of findings from animal research to human pathophysiology, and also contain sections on future directions which will be of special interest to basic and clinical researchers working on liver fibrosis, hepatic biology, and pathobiology. Presents coverage of the mechanisms of liver fibrosis with stellate cells as a target for therapy. Shows stellate cells as a major participant in hepatic immunobiology, including transplantation immunology. Key illustrations show the phenotypical changes in stellate cells in situ and tissue culture, their interactions with other cell types, signaling pathways and demonstrate the functions and roles of stellate cell in pathological processes.

Biology of Myelomonocytic Cells

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Publisher : BoD – Books on Demand
ISBN 13 : 9535131230
Total Pages : 174 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Biology of Myelomonocytic Cells by : Anirban Ghosh

Download or read book Biology of Myelomonocytic Cells written by Anirban Ghosh and published by BoD – Books on Demand. This book was released on 2017-05-10 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: Myelomonocytes are the multipotent cells in the stage of blood cell differentiation, which mainly comprise blood monocytes, tissue macrophages and subset of dendritic cells. Actually, their position and ability of judgement of the health of tissue or organ environment are the key initiators of tissue-specific immune response in a local and global fashion. Interestingly, the morpho-functional aspects of this group of cells vary to a wide range with their positional diversity. Their ability to communicate or represent the tissue microenvironment to the peripheral immune system and efficiency to engage the system to effector activation hold the key for a successful immune endeavour. The present volume shows some glimpses of such an extensive area of current immunology research.

Macrophages: Biology and Role in the Pathology of Diseases

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Publisher : Springer
ISBN 13 : 1493913115
Total Pages : 603 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Macrophages: Biology and Role in the Pathology of Diseases by : Subhra K. Biswas

Download or read book Macrophages: Biology and Role in the Pathology of Diseases written by Subhra K. Biswas and published by Springer. This book was released on 2014-11-12 with total page 603 pages. Available in PDF, EPUB and Kindle. Book excerpt: Macrophages are a key component of the innate immune system and play an integral role in host defense and homeostasis. On one hand, these cells contribute to host defence by triggering inflammation, displaying microbicidal/tumoricidal properties, regulating the activation of adaptive immunity and promoting resolution of inflammation. On the other hand, they contribute to essential trophic functions such as neural patterning, bone morphogenesis and ductal branching in mammary glands. Thus, macrophages are extremely versatile cells that can respond efficiently to tissue micro environmental cues by polarizing to distinct phenotypes, depending on the functions they need to perform. Indeed, functional diversity and plasticity are hallmarks of these cells. Macrophages may also play a detrimental role. An overwhelming body of literature has indicated their crucial role in pathogenesis. The list includes sepsis, cancer, metabolic syndrome, immunodeficiency, auto-immune disease-virtually impacting every major pathology that we know. These observations have suggested macrophages and their related molecules as potential targets in therapeutic applications. Available evidence proclaims macrophages as a key player in homeostasis, host defense and disease. Crucial developments in the past few years call for a re-evaluation and update of our understanding of macrophages. The present book is an endeavour that attempts provide state-of-the art knowledge of these cells in health and disease.

Hepatocyte and Kupffer Cell Interactions (1992)

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Author :
Publisher : CRC Press
ISBN 13 : 1351361678
Total Pages : 413 pages
Book Rating : 4.3/5 (513 download)

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Book Synopsis Hepatocyte and Kupffer Cell Interactions (1992) by : Timothy R. Billiar

Download or read book Hepatocyte and Kupffer Cell Interactions (1992) written by Timothy R. Billiar and published by CRC Press. This book was released on 2017-11-22 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hepatocyte and Kupffer Cell Interactions presents a comprehensive discussion of historical and recent information regarding this diverse field of research. The role of Kupffer cells and hepatoctyes in normal physiology, nonseptic pathological states, and in sepsis is examined. Microanatomy and methods of experimental study are covered as well. In each of the book's chapters, the role of the Kupffer cell and hepatocyte interaction is placed in context with information on particular liver functions or disease states. Hepatocyte and Kupffer Cell Interactions is an essential reference for leukocyte specialists, gastroenterologists, immunologists, and other researchers working in this fascinating field.

Kupffer Cells

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Publisher : Humana
ISBN 13 : 9781071607060
Total Pages : 160 pages
Book Rating : 4.6/5 (7 download)

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Book Synopsis Kupffer Cells by : Myriam Aouadi

Download or read book Kupffer Cells written by Myriam Aouadi and published by Humana. This book was released on 2021-07-15 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a complete overview of kupffer cell biology, from isolation to phenotyping. Chapters guide readers through methods and protocols on phenotyping, including RNA sequencing, Mass cytometry and 3D microscopy, as well as gene manipulation in vivo, and disease models from fatty liver disease to cancer. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Kupffer Cells: Methods and Protocols aims to ensure successful investigation of this growing field.

Alpha-1 Antitrypsin Deficiency

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Author :
Publisher :
ISBN 13 : 9781493971633
Total Pages : 278 pages
Book Rating : 4.9/5 (716 download)

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Book Synopsis Alpha-1 Antitrypsin Deficiency by : Florie Borel

Download or read book Alpha-1 Antitrypsin Deficiency written by Florie Borel and published by . This book was released on 2017 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides protocols that expand on the latest alpha-1 antitrypsin (AAT) research. The chapters in this book are divided in to three sections: Part I is dedicated to patient-oriented research; part II discusses animal models; and Part III focuses on in vitro studies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and authoritative, Alpha-1 Antitrypsin Deficiency: Methods and Protocols is a valuable resource for researchers, students, and clinican-scientists interested in AAT deficiency, as well as anyone working in the fields of pulmonology and hepatology.

Kupffer Cells

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Author :
Publisher : Humana
ISBN 13 : 9781071607039
Total Pages : 0 pages
Book Rating : 4.6/5 (7 download)

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Book Synopsis Kupffer Cells by : Myriam Aouadi

Download or read book Kupffer Cells written by Myriam Aouadi and published by Humana. This book was released on 2020-07-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a complete overview of kupffer cell biology, from isolation to phenotyping. Chapters guide readers through methods and protocols on phenotyping, including RNA sequencing, Mass cytometry and 3D microscopy, as well as gene manipulation in vivo, and disease models from fatty liver disease to cancer. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Kupffer Cells: Methods and Protocols aims to ensure successful investigation of this growing field.

Liver Pathophysiology

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Publisher : Academic Press
ISBN 13 : 0128043210
Total Pages : 914 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Liver Pathophysiology by : Pablo Muriel

Download or read book Liver Pathophysiology written by Pablo Muriel and published by Academic Press. This book was released on 2017-03-02 with total page 914 pages. Available in PDF, EPUB and Kindle. Book excerpt: Liver Pathophysiology: Therapies and Antioxidants is a complete volume on morphology, physiology, biochemistry, molecular biology and treatment of liver diseases. It uses an integral approach towards the role of free radicals in the pathogenesis of hepatic injury, and how their deleterious effects may be abrogated by the use of antioxidants. Written by the most prominent authors in the field, this book will be of use to basic and clinical scientists and clinicians working in the biological sciences, especially those dedicated to the study and treatment of liver pathologies. Presents the most recent advances in hepatology, with a special focus on the role of oxidative stress in liver injury. Provides in vivo and in vitro models to study human liver pathology. Explains the beneficial effects of antioxidants on liver diseases. Contains the most recent and modern treatments of hepatic pathologies, including, but not limited to, stem cells repopulation, gene therapy and liver transplantation.

Taurine 10

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Publisher : Springer
ISBN 13 : 9402410791
Total Pages : 1181 pages
Book Rating : 4.4/5 (24 download)

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Book Synopsis Taurine 10 by : Dong-Hee Lee

Download or read book Taurine 10 written by Dong-Hee Lee and published by Springer. This book was released on 2017-08-28 with total page 1181 pages. Available in PDF, EPUB and Kindle. Book excerpt: Taurine 10 contains original articles and critical reviews based on the oral and poster presentations of XX International Taurine Meeting held in Seoul, Korea in May 2016. The purpose of the book is to present current ideas, new avenues and research regarding biological functions and clinical applications of taurine and taurine derivatives. It focuses on all aspects of taurine research including the cardiovascular system, the immune system, diabetes, the central nervous system, endocrine system and the role of taurine supplements in nutrition. It also includes presentations of novel animal experimental models using Cdo1 and CSAD knock-out mice.

Antimicrobial Immune Response

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Publisher : BoD – Books on Demand
ISBN 13 : 1839687827
Total Pages : 102 pages
Book Rating : 4.8/5 (396 download)

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Book Synopsis Antimicrobial Immune Response by : Maria Del Mar Ortega-Villaizan

Download or read book Antimicrobial Immune Response written by Maria Del Mar Ortega-Villaizan and published by BoD – Books on Demand. This book was released on 2021-11-24 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious microbial agents such as viruses, bacteria, fungi, and parasites can cause pathological disorders and even death in organisms exposed to the environment. However, organisms have an immune system to control infection caused by pathogens. The immune system is divided into the innate and the adaptive immune systems. The innate immune system is the first mechanism to respond to infections, whereas the adaptive immune system is based on immune memory. This book provides an overview of antiviral and antibacterial immune responses in different immune-reactive organs and across different animal species, from higher to lower vertebrates.

Signaling Pathways in Liver Diseases

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Publisher : John Wiley & Sons
ISBN 13 : 1118663365
Total Pages : 520 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Signaling Pathways in Liver Diseases by : Jean-Francois Dufour

Download or read book Signaling Pathways in Liver Diseases written by Jean-Francois Dufour and published by John Wiley & Sons. This book was released on 2015-08-24 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Signaling Pathways in Liver Diseases, Third Edition again provides hepatologists and hepatology researchers with an expert overview of the complex and novel cellular/extracellular signaling pathways in the liver, and their role in liver diseases. The last few years have seen a great number of developments in this field, which in turn have led to new opportunities for innovative treatments; however, the intricacy of these pathways and their interactions continue to provide a real challenge for clinicians. This outstanding book compiles the emerging knowledge into a single expert resource, cataloguing and organizing it into an accessible and understandable format. With increased focus on the comprehension of cellular mechanisms involved in steatohepatitis, cirrhosis, and liver tumors, which has led to changes in the management of these diseases, this new edition also sees the introduction of exciting new chapters on key emerging areas such as: Autophagy Notch Pathway P13K/PTEN Signaling in Liver Diseases Sirtuins Hepcidin and Iron Epigenetic Regulation of Hepatic Stellate Cells and Liver Fibrosis Oxidative Stress and Signaling in the Liver. Professors Dufour and Clavien have assembled an all-star cast of chapter authors, each of whom has provided clear and appropriate illustrations to reinforce the text, with a key points box offering a concise and handy summary. Self-assessment questions and answers allow the reader to test their own knowledge. Signaling Pathways in Liver Disease, Third Edition is the perfect educational and reference tool to bridge the information exchange between the laboratory, the clinical ward, and the operating room, and an essential tool for the modern-day hepatologist.

Liver Transplantation

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Publisher : John Wiley & Sons
ISBN 13 : 1119633990
Total Pages : 592 pages
Book Rating : 4.1/5 (196 download)

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Book Synopsis Liver Transplantation by : James Neuberger

Download or read book Liver Transplantation written by James Neuberger and published by John Wiley & Sons. This book was released on 2021-02-25 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explore this practical and step-by-step guide to managing liver transplant patients from leading international clinicians in Hepatology The newly revised Second Edition of Liver Transplantation: Clinical Assessment and Management delivers expert clinical guidance on best practices in managing the care of liver transplant patients. Authors are all experts in their field and cover a world-wide perspective. Organized in an accessible, stepwise fashion and packed with text features such as key points, the book covers all critical areas of each stage of the liver transplant journey, from assessment, to management on the list, to long term care. Readers will learn when to refer a patient for liver transplantation, how to assess a potential liver transplant recipient, learn the principles of the procedure and the long term management of the transplant recipient. Liver Transplantation provides the entire hepatology and surgical team the information required for a sound understanding of the entire procedure, from pre- to post-operative care and management. Clinically oriented and management-focused, the book is far more accessible than the liver transplant sections in traditional hepatology textbooks. Readers will also enjoy: A thorough discussion of when to refer a patient for liver transplantation, including general considerations and the use and abuse of prognostic models An exploration of the selection, assessment, and management of patients on the transplant list, including how to manage a patient with chronic liver disease while on the waiting list A treatment of liver transplantation for acute liver failure (ALF), including assessment and management of ALF patients on the transplant waiting list A discussion of care of the liver transplant recipient after the procedure in the short and long term Perfect for gastroenterologists, hepatologists, and surgeons and other health care professionals managing patients with liver disease who are awaiting, undergoing and following liver transplantation, Liver Transplantation: Clinical Assessment and Management will also earn a place in the libraries of medical students, residents, internal medicine physicians, and GI/Hepatology trainees and all health care professionals providing clinical care to people with liver disease, before, during and after transplantation.

Liver Diseases and Hepatic Sinusoidal Cells

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Author :
Publisher : Springer
ISBN 13 : 9784431680123
Total Pages : 0 pages
Book Rating : 4.6/5 (81 download)

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Book Synopsis Liver Diseases and Hepatic Sinusoidal Cells by : Kyuichi Tanikawa

Download or read book Liver Diseases and Hepatic Sinusoidal Cells written by Kyuichi Tanikawa and published by Springer. This book was released on 2013-10-03 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hepatic sinusoidal cells such as sinusoidal endothelial cells, Kupffer cells, hepatic stellate cells, and pit cells play an important role in hemodynamic and metabolic function and are involved in various liver diseases. The frequent involvement of sinusoidal cells in pathologic conditions is explained by the diverse actions of those cells, an understanding of which is essential to clinicians. Generously illustrated, this volume presents results of recent studies on hepatic sinusoidal cells in liver diseases, with an introduction to the structure and function of the various types of sinusoidal cells. The in-depth focus of the book is on the role of hepatic sinusoidal cells in relation to liver injury and regeneration, hepatic sinusoidal microcirculation, alcoholic liver diseases, hepatic fibrosis, liver tumor, liver transplantation, cholestasis, and congenital lipidosis, thus providing a valuable reference source for practitioners and researchers.

Molecules, Systems and Signaling in Liver Injury

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Publisher : Springer
ISBN 13 : 9783319863221
Total Pages : 0 pages
Book Rating : 4.8/5 (632 download)

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Book Synopsis Molecules, Systems and Signaling in Liver Injury by : Wen-Xing Ding

Download or read book Molecules, Systems and Signaling in Liver Injury written by Wen-Xing Ding and published by Springer. This book was released on 2018-08-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This essential volume presents comprehensive information on cell death and autophagy in liver diseases, including the role and molecular signaling pathways of cell death in alcohol and non-alcoholic fatty liver disease, bile acids, hepatitis C virus and drug-induced liver injury. The book starts with a discussion of lipotoxicity in non-parenchymal cells, followed by a discussion of cell death and autophagy in cholangiocytes, hepatic stellate cells and Kupffer cells in hepatic biliary diseases, fibrosis and liver inflammation. The book also covers Bcl-2 family proteins, beta-catenin and HMGB1 signaling in regulating cell death in the liver as well as mitochondria, ER stress and gut microbiota on liver injury. The Cell Death in Biology and Diseases series has recruited world experts ranging from basic scientists to clinicians on cell death in liver diseases. Likewise the contributors of this volume are leaders in their fields with worldwide expertise and perspective. Molecul es, Systems and Signaling in Liver Injury is an essential companion to Hepatocytes and Non-Parenchymal Cells and Diseases. It is beneficial for both clinicians and basic scientists and is relevant to those working on drug discovery for preventing and treating liver diseases by targeting cell death and autophagy pathways.

The Stem Cell Niche during Ageing

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Publisher : Academic Press
ISBN 13 : 0128220198
Total Pages : 252 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis The Stem Cell Niche during Ageing by : Susie Prof. Nilsson

Download or read book The Stem Cell Niche during Ageing written by Susie Prof. Nilsson and published by Academic Press. This book was released on 2020-09-08 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Stem Cells and Their Niches addresses stem cells during development, homeostasis, and disease/injury of the respective organs, presenting new developments in the field, including new data on disease and clinical applications. Video content illustrates such areas as protocols, transplantation techniques, and work with mice. Explores not only reviews of research, but also shares methods, protocols, and transplantation techniques Contains video content to illustrate such areas as protocols, transplantation techniques, and work with mice Each volume concentrates on one organ, making this a unique publication

Kupffer Cells and Other Liver Sinusoidal Cells

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Author :
Publisher : North-Holland
ISBN 13 :
Total Pages : 586 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis Kupffer Cells and Other Liver Sinusoidal Cells by : E. Wisse

Download or read book Kupffer Cells and Other Liver Sinusoidal Cells written by E. Wisse and published by North-Holland. This book was released on 1977 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: