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Knockdown

Author : William W. Johnstone
Publisher : Pinnacle Books
ISBN 13 : 0786044292
Total Pages : 322 pages
Book Rating : 4.7/5 (86 download)

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Book Synopsis Knockdown by : William W. Johnstone

Download or read book Knockdown written by William W. Johnstone and published by Pinnacle Books. This book was released on 2020-08-25 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: JOHNSTONE COUNTRY. WHERE THE WILL DEFIES FEAR. They call him “The Rig Warrior.” Name: Barry Rivers. Occupation: Long haul trucker. Special skills: Defender of freedom. Patriot. Government sanctioned killer. A NATION OFF THE RAILS No one saw the first attack coming. A perfectly orchestrated assault on a mass-transit railroad line that left countless Americans dead. Then came more attacks. More rail systems sabotaged. More civilian lives lost. Intelligence experts are convinced this is no ordinary terrorist attack. To pull off something like this, it would take a deep-state traitor with dark foreign connections. And to stop them, it will take someone who isn’t afraid to shed blood. A HERO OFF THE GRID Enter Barry Rivers, the Rig Warrior. An urban legend in the intelligence community, Rivers has been living off the radar for years. But when he sees his country under attack, he reaches out to his son in the FBI to track down the enemies in our own government. To these high-ranking traitors, Rivers is a threat to their global agenda. But when Rivers revs up his tricked-out 18-wheeler—and goes after a runaway train on a collision course with disaster—all bets are off. The war is on. And with Barry Rivers at the wheel, it’s going to be the ultimate knockdown, drag-out fight for America’s future . . . Live Free. Read Hard.

Knockdown Knits

Author : Toni Carr
Publisher : Turner Publishing Company
ISBN 13 : 047038865X
Total Pages : 405 pages
Book Rating : 4.4/5 (73 download)

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Book Synopsis Knockdown Knits by : Toni Carr

Download or read book Knockdown Knits written by Toni Carr and published by Turner Publishing Company. This book was released on 2008-10-13 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Knit neat items inspired by sassy roller derby girls with the thirty hip knitting patterns that you will find in Knockdown Knits: 30 Projects from the Roller Derby Track. Roller derby, with its cheeky players, fast-paced jams, heart-stopping pileups, and rowdy, raucous atmosphere, is just as hot as the designs in this unconventional book. The Naptown Roller Girls of Indianapolis, Indiana, share the patterns they use when they’re knitting in the off-time. On skates, they're hell on wheels; in their spare time, they've discovered that knitting is a relaxing, creative outlet.

Knockdown

Author : Sarah Graves
Publisher : Bantam
ISBN 13 : 0440423120
Total Pages : 289 pages
Book Rating : 4.4/5 (44 download)

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Book Synopsis Knockdown by : Sarah Graves

Download or read book Knockdown written by Sarah Graves and published by Bantam. This book was released on 2011-04-26 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: Jacobia “Jake” Tiptree is deep in her latest home improvement project—repainting the porch of her lovingly restored house in Eastport, Maine—when she notices the man repeatedly biking past her house. His face is unsettlingly familiar, but his chilling message seems inexplicable: Blood shows up again. Murder will out. Then there’s the anonymous email warning her to beware the Fourth of July—just two days away. Jake remembers some shady characters from her days as a hotshot financial manager, but she’s baffled as to the identity of her nemesis—until she receives a photo of a murdered man. From home invasion to kidnapping, this twisted killer is slowly but surely plotting a knockdown, not just for Jake but for the entire town of Eastport. BONUS: This edition includes an excerpt from Sarah Graves's Dead Level.

Systems Biology and the Challenge of Deciphering the Metabolic Mechanisms Underlying Cancer

Author : Osbaldo Resendis-Antonio
Publisher : Frontiers Media SA
ISBN 13 : 2889453332
Total Pages : 144 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Systems Biology and the Challenge of Deciphering the Metabolic Mechanisms Underlying Cancer by : Osbaldo Resendis-Antonio

Download or read book Systems Biology and the Challenge of Deciphering the Metabolic Mechanisms Underlying Cancer written by Osbaldo Resendis-Antonio and published by Frontiers Media SA. This book was released on 2017-11-23 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the discovery of the Warburg effect in the 1920s cancer has been tightly associated with the genetic and metabolic state of the cell. One of the hallmarks of cancer is the alteration of the cellular metabolism in order to promote proliferation and undermine cellular defense mechanisms such as apoptosis or detection by the immune system. However, the strategies by which this is achieved in different cancers and sometimes even in different patients of the same cancer is very heterogeneous, which hinders the design of general treatment options. Recently, there has been an ongoing effort to study this phenomenon on a genomic scale in order to understand the causality underlying the disease. Hence, current “omics” technologies have contributed to identify and monitor different biological pieces at different biological levels, such as genes, proteins or metabolites. These technological capacities have provided us with vast amounts of clinical data where a single patient may often give rise to various tissue samples, each of them being characterized in detail by genomescale data on the sequence, expression, proteome and metabolome level. Data with such detail poses the imminent problem of extracting meaningful interpretations and translating them into specific treatment options. To this purpose, Systems Biology provides a set of promising computational tools in order to decipher the mechanisms driving a healthy cell’s metabolism into a cancerous one. However, this enterprise requires bridging the gap between large data resources, mathematical analysis and modeling specifically designed to work with the available data. This is by no means trivial and requires high levels of communication and adaptation between the experimental and theoretical side of research.

Molecular Biology of Bamboo Mosaic Virus – A Type Member of the Potexvirus Genus

Author : Yau-Heiu Hsu
Publisher : Frontiers Media SA
ISBN 13 : 2889454398
Total Pages : 109 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Molecular Biology of Bamboo Mosaic Virus – A Type Member of the Potexvirus Genus by : Yau-Heiu Hsu

Download or read book Molecular Biology of Bamboo Mosaic Virus – A Type Member of the Potexvirus Genus written by Yau-Heiu Hsu and published by Frontiers Media SA. This book was released on 2018-04-06 with total page 109 pages. Available in PDF, EPUB and Kindle. Book excerpt: The flexible filamentous plant viruses are responsible for more than half of all agricultural loss worldwide. Potexvirus is one of the two most important flexible filamentous plant viruses. Bamboo mosaic virus (BaMV), a single-stranded positive-sense RNA virus, is a member of the Potexvirus genus of Alphaflexiviridae. It can infect at least 12 species of bamboo, causing a huge economic impact on the bamboo industry in Taiwan. The study of BaMV did not start extensively until the completion of the full-length sequencing of genomic RNA of BaMV and generation of the BaMV infectious cDNA clone in the early 1990s. Since then, BaMV has been extensively studied at the molecular, cellular and ecological level, covering both basic and applied researches, by a group of researchers in Taiwan. In this eBook, the content comprises 6 reviews and 4 articles. Seven of them are involved in the infection of BaMV covering viral RNA replication, viral RNA trafficking, and the host factors. Two of them are related to the vector transmission and the ecology of BaMV. The last one is the application of using BaMV as a viral vector to produce vaccines in plants.

RNA Interference

Author : Ibrokhim Y. Abdurakhmonov
Publisher : BoD – Books on Demand
ISBN 13 : 953512272X
Total Pages : 460 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis RNA Interference by : Ibrokhim Y. Abdurakhmonov

Download or read book RNA Interference written by Ibrokhim Y. Abdurakhmonov and published by BoD – Books on Demand. This book was released on 2016-04-06 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: RNA interference (RNAi), a hallmark of all biological sciences of twenty-first century, is an evolutionarily conserved and double-stranded RNA-dependent eukaryotic cell defense process. Opportunity to utilize an organisms own gene and to systematically induce and trigger RNAi for any desired sequence made RNAi an efficient approach for functional genomics, providing a solution for conventional longstanding obstacles in life sciences. RNAi research and application have significantly advanced during past two decades. This book RNA interference provides an updated knowledge and progress on RNAi in various organisms, explaining basic principles, types, and property of inducers, structural modifications, delivery systems/methodologies, and various successful bench-to-field or clinic applications and disease therapies with some aspects of limitations, alternative tools, safety, and risk assessment.

Cerebellum as a CNS Hub

Author : Hidehiro Mizusawa
Publisher : Springer Nature
ISBN 13 : 3030758176
Total Pages : 543 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis Cerebellum as a CNS Hub by : Hidehiro Mizusawa

Download or read book Cerebellum as a CNS Hub written by Hidehiro Mizusawa and published by Springer Nature. This book was released on 2021-11-10 with total page 543 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on the 75th Fujihara Seminar held in December 2018 in Tokyo, Japan, this volume explores the latest research on the cerebellum. Contributors seek to examine the cerebellum's role as a unique hub for brain activity and discover new information about its purpose. The discussion is broad, ranging from evolutionary topics to therapeutic strategy and addresses both physiology and pathology. Subjects covered include anatomy, information processing, complex spikes, plasticity, modeling, and spinocerebellar ataxias. The volume is intended to set the stage for the future of cerebellar research and guide both basic and clinical researchers.

RNA Diseases in Humans – From Fundamental Research to Therapeutic Applications

Author : Naoyuki Kataoka
Publisher : Frontiers Media SA
ISBN 13 : 2889630978
Total Pages : 123 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis RNA Diseases in Humans – From Fundamental Research to Therapeutic Applications by : Naoyuki Kataoka

Download or read book RNA Diseases in Humans – From Fundamental Research to Therapeutic Applications written by Naoyuki Kataoka and published by Frontiers Media SA. This book was released on 2019-10-15 with total page 123 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Research Topic addresses the human diseases caused by a malfunction of the RNA metabolism. We aim at strengthening the link between fundamental research and therapeutic applications. In eukaryotes, RNA is transcribed from genomic DNA. RNA molecules undergo multiple post-transcriptional processes such as splicing, editing, modification, translation, and degradation. A defect, mis-regulation, or malfunction of these processes often results in diseases in humans, referred to as 'RNA diseases'. There is an increasing number of studies focused on RNA diseases, which are aimed at uncovering the fundamental molecular mechanisms at play in order to develop therapeutic approaches.

Development, metabolism, senescence and mechanotransduction of bone

Author : Airong Qian
Publisher : Frontiers Media SA
ISBN 13 : 2832511201
Total Pages : 136 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Development, metabolism, senescence and mechanotransduction of bone by : Airong Qian

Download or read book Development, metabolism, senescence and mechanotransduction of bone written by Airong Qian and published by Frontiers Media SA. This book was released on 2023-01-09 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Arthropod Diversity and Conservation in the Tropics and Sub-tropics

Author : Akshay Kumar Chakravarthy
Publisher : Springer
ISBN 13 : 981101518X
Total Pages : 443 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Arthropod Diversity and Conservation in the Tropics and Sub-tropics by : Akshay Kumar Chakravarthy

Download or read book Arthropod Diversity and Conservation in the Tropics and Sub-tropics written by Akshay Kumar Chakravarthy and published by Springer. This book was released on 2016-11-23 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: Arthropods are invertebrates that constitute over 90% of the animal kingdom, and their bio-ecology is closely linked with global functioning and survival. Arthropods play an important role in maintaining the health of ecosystems, provide livelihoods and nutrition to human communities, and are important indicators of environmental change. Yet the population trends of several arthropods species show them to be in decline. Arthropods constitute a dominant group with 1.2 million species influencing earth’s biodiversity. Among arthropods, insects are predominant, with ca. 1 million species and having evolved some 350 million years ago. Arthropods are closely associated with living and non-living entities alike, making the ecosystem services they provide crucially important. In order to be effective, plans for the conservation of arthropods and ecosystems should include a mixture of strategies like protecting key habitats and genomic studies to formulate relevant policies for in situ and ex situ conservation. This two-volume book focuses on capturing the essentials of arthropod inventories, biology, and conservation.Further, it seeks to identify the mechanisms by which arthropod populations can be sustained in terrestrial and aquatic ecosystems, and by means of which certain problematic species be managed without producing harmful environmental side-effects. This edited compilation includes chapters contributed by over 80 biologists on a wide range of topics embracing the diversity, distribution, utility and conservation of arthropods and select groups of insect taxa. More importantly, it describes in detail the mechanisms of sustaining arthropod ecosystems, services and populations. It addresses the contribution of modern biological tools such as molecular and genetic techniques regulating gene expression, as well as conventional, indigenous practices in arthropod conservation. The contributors reiterate the importance of documenting and understanding the biology of arthropods from a holistic perspective before addressing conservation issues at large. This book offers a valuable resource for all zoologists, entomologists, ecologists, conservation biologists, policy makers, teachers and students interested in the conservation of biological resources.

Issues in Cancer Treatment and Therapy: 2013 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 149010884X
Total Pages : 269 pages
Book Rating : 4.4/5 (91 download)

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Book Synopsis Issues in Cancer Treatment and Therapy: 2013 Edition by :

Download or read book Issues in Cancer Treatment and Therapy: 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-05-01 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: Issues in Cancer Treatment and Therapy / 2013 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Additional Research in a concise format. The editors have built Issues in Cancer Treatment and Therapy: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Additional Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Cancer Treatment and Therapy: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Sodium Calcium Exchange: A Growing Spectrum of Pathophysiological Implications

Author : Lucio Annunziato
Publisher : Springer Science & Business Media
ISBN 13 : 1461447569
Total Pages : 457 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Sodium Calcium Exchange: A Growing Spectrum of Pathophysiological Implications by : Lucio Annunziato

Download or read book Sodium Calcium Exchange: A Growing Spectrum of Pathophysiological Implications written by Lucio Annunziato and published by Springer Science & Business Media. This book was released on 2012-12-09 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reports the text of the lectures of the 6th International Conference on Sodium Calcium Exchange held in Lacco Ameno in the Island of Ischia in the Gulf of Naples, Italy, from October 1 to October 5, 2011. The present book uncovers the most striking new findings on NCX that emerged since the previous Conference on Sodium Calcium Exchange, such as the structural dissection of the molecular determinants of Ca2+ sensitivity of the exchanger, the epigenetic regulation of ncx1 gene, the molecular identification of the mitochondrial Sodium Calcium Exchanger, and the discovery of NCX in unexpected anatomical locations such as the female reproductive tract. The book is organized into 11 parts covering NCX structural aspects, genetic and epigenetic regulation, regulatory mechanisms, subcellular localization in mitochondria, involvement in neurodegenerative diseases and in immune regulation, and the role of the cardiovascular and endocrine systems, as well as diabetes in physiology and pathophysiology. Selected chapters of the book are also devoted to the interaction of NCKX and other ion channels and transporters with NCX, like ASICs, TRPM, and NHE.

Identification and Functional Dissection of Stress-responsive Genes in Cotton

Author : Jia-He Wu
Publisher : Frontiers Media SA
ISBN 13 : 2832506593
Total Pages : 415 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Identification and Functional Dissection of Stress-responsive Genes in Cotton by : Jia-He Wu

Download or read book Identification and Functional Dissection of Stress-responsive Genes in Cotton written by Jia-He Wu and published by Frontiers Media SA. This book was released on 2022-11-22 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Knock Down Dragon Out

Author : Krystal Shannan
Publisher :
ISBN 13 : 9781386969129
Total Pages : pages
Book Rating : 4.9/5 (691 download)

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Book Synopsis Knock Down Dragon Out by : Krystal Shannan

Download or read book Knock Down Dragon Out written by Krystal Shannan and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: His black heart wants only vengeance...until she needs him... Unable to save his family from murdering traitors, Col has a mission: to kill the dragons who murdered the royal house of Li'Vhram. When a cute, curvy woman needs rescuing, though, his senses go on high alert. And her soul is calling directly to him. That only happens... ...with soulmates. But Col made a vow. He must avenge his family. He can't fall in love with her, no matter how much his inner dragon roars "mate" every five minutes.An overwhelming need to get away from life—from grief—sent Naomi on a trek through Alaska. Even though she was expecting to photograph some unique wildlife, she was NOT expecting a dragon.Those don't exist, right? And a dragon who turns into a human? Even more unlikely. A hot dragon prince... yeah, she's totally hallucinating. And when he won't leave her side, and their chemistry is off the charts, suddenly, it's a whole-new-world of fantasy and excitement, until danger finds her.Warning: This series contains a group of sexy warrior shifters, plenty of exciting action, and melt-your-phone-sexy scenes.

Sourcebook of Models for Biomedical Research

Author : P. Michael Conn
Publisher : Springer Science & Business Media
ISBN 13 : 1597452858
Total Pages : 756 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis Sourcebook of Models for Biomedical Research by : P. Michael Conn

Download or read book Sourcebook of Models for Biomedical Research written by P. Michael Conn and published by Springer Science & Business Media. This book was released on 2008-03-07 with total page 756 pages. Available in PDF, EPUB and Kindle. Book excerpt: The collection of systems represented in this volume is a unique effort to reflect the diversity and utility of models used in biomedicine. That utility is based on the consideration that observations made in particular organisms will provide insight into the workings of other, more complex systems. This volume is therefore a comprehensive and extensive collection of these important medical parallels.

Definitions of Revised Classes and Subclasses of Subjects of Invention in the United States Patent Office

Author : United States. Patent Office
Publisher :
ISBN 13 :
Total Pages : 506 pages
Book Rating : 4.:/5 (321 download)

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Book Synopsis Definitions of Revised Classes and Subclasses of Subjects of Invention in the United States Patent Office by : United States. Patent Office

Download or read book Definitions of Revised Classes and Subclasses of Subjects of Invention in the United States Patent Office written by United States. Patent Office and published by . This book was released on 1912 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Methods in Stem Cell Biology - Part B

Author :
Publisher : Academic Press
ISBN 13 : 0323900194
Total Pages : 262 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Methods in Stem Cell Biology - Part B by :

Download or read book Methods in Stem Cell Biology - Part B written by and published by Academic Press. This book was released on 2022-08-09 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods in Cancer Stem Cell Biology: Part B, Volume 171 in the Methods in Cell Biology series highlights advances in the field, with this new volume presenting interesting chapters on timely topics, including Orthotopic brain tumor models derived from glioblastoma stem-like cells, RNA sequencing in hematopoietic stem cells, Generation of inducible pluripotent stem cells from human dermal fibroblasts, In vitro preparation of dental pulp stem cell grafts combined with biocompatible scaffolds for tissue engineering, Gene expression knockdown in chronic myeloid leukemia stem cells, Identification and isolation of slow-cycling GSCs, Assessment of CD133, EpCAM, and much more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Methods in Cell Biology series - Includes the latest information on the topic of Methods in Cancer Stem Cell Biology