High-Pressure Crystallography

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Publisher : Springer Science & Business Media
ISBN 13 : 140202102X
Total Pages : 574 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis High-Pressure Crystallography by : Andrzej Katrusiak

Download or read book High-Pressure Crystallography written by Andrzej Katrusiak and published by Springer Science & Business Media. This book was released on 2004-03-31 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite the tremendous advances in the techniques and equipment for carrying out high-pressure crystallography, the application or exploration of the high-pressure variable in detailed structural studies remains rare. The chapters in this book provide a set of lecture notes and supplementary material for a course on high pressure crystallography. The material comprises state-of-the-art reviews of high-pressure experiments using X-ray and neutron diffraction techniques at synchrotron and neutron facilities and in the laboratory, as well as complementary experimental high-pressure techniques and theoretical methods for investigating matter at elevated pressures. The materials studies range from elemental solids and liquids to inorganic compounds, minerals, organic compounds, clathrates and pharmaceutical compounds, to large biological molecules such as proteins and viruses. The book provides a reference for workers in high-pressure science wishing to learn more about crystallography and for established crystallographers potentially interested in high pressure as a variable, as well as an introductory guide to new researchers in the field.

Understanding Intermolecular Interactions in the Solid State

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Publisher : Royal Society of Chemistry
ISBN 13 : 1788015169
Total Pages : 358 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis Understanding Intermolecular Interactions in the Solid State by : Deepak Chopra

Download or read book Understanding Intermolecular Interactions in the Solid State written by Deepak Chopra and published by Royal Society of Chemistry. This book was released on 2018-09-04 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Technological and computational advances in the past decade have meant a vast increase in the study of crystalline matter in both organic, inorganic and organometallic molecules. These studies revealed information about the conformation of molecules and their coordination geometry as well as the role of intermolecular interactions in molecular packing especially in the presence of different intermolecular interactions in solids. This resulting knowledge plays a significant role in the design of improved medicinal, mechanical, and electronic properties of single and multi-component solids in their crystalline state. Understanding Intermolecular Interactions in the Solid State explores the different techniques used to investigate the interactions, including hydrogen and halogen bonds, lone pair–pi, and pi–pi interactions, and their role in crystal formation. From experimental to computational approaches, the book covers the latest techniques in crystallography, ranging from high pressure and in situ crystallization to crystal structure prediction and charge density analysis. Thus this book provides a strong introductory platform to those new to this field and an overview for those already working in the area. A useful resource for higher level undergraduates, postgraduates and researchers across crystal engineering, crystallography, physical chemistry, solid-state chemistry, supramolecular chemistry and materials science.

Pharmaceutical Crystals

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Publisher : John Wiley & Sons
ISBN 13 : 1119046297
Total Pages : 432 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis Pharmaceutical Crystals by : Tong Li

Download or read book Pharmaceutical Crystals written by Tong Li and published by John Wiley & Sons. This book was released on 2018-10-16 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: An important resource that puts the focus on understanding and handling of organic crystals in drug development Since a majority of pharmaceutical solid-state materials are organic crystals, their handling and processing are critical aspects of drug development. Pharmaceutical Crystals: Science and Engineering offers an introduction to and thorough coverage of organic crystals, and explores the essential role they play in drug development and manufacturing. Written contributions from leading researchers and practitioners in the field, this vital resource provides the fundamental knowledge and explains the connection between pharmaceutically relevant properties and the structure of a crystal. Comprehensive in scope, the text covers a range of topics including: crystallization, molecular interactions, polymorphism, analytical methods, processing, and chemical stability. The authors clearly show how to find solutions for pharmaceutical form selection and crystallization processes. Designed to be an accessible guide, this book represents a valuable resource for improving the drug development process of small drug molecules. This important text: Includes the most important aspects of solid-state organic chemistry and its role in drug development Offers solutions for pharmaceutical form selection and crystallization processes Contains a balance between the scientific fundamental and pharmaceutical applications Presents coverage of crystallography, molecular interactions, polymorphism, analytical methods, processing, and chemical stability Written for both practicing pharmaceutical scientists, engineers, and senior undergraduate and graduate students studying pharmaceutical solid-state materials, Pharmaceutical Crystals: Science and Engineering is a reference and textbook for understanding, producing, analyzing, and designing organic crystals which is an imperative skill to master for anyone working in the field.

Innovative Dosage Forms

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Publisher : John Wiley & Sons
ISBN 13 : 3527812202
Total Pages : 474 pages
Book Rating : 4.5/5 (278 download)

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Book Synopsis Innovative Dosage Forms by : Yogeshwar Bachhav

Download or read book Innovative Dosage Forms written by Yogeshwar Bachhav and published by John Wiley & Sons. This book was released on 2019-08-09 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Teaches future and current drug developers the latest innovations in drug formulation design and optimization This highly accessible, practice-oriented book examines current approaches in the development of drug formulations for preclinical and clinical studies, including the use of functional excipients to enhance solubility and stability. It covers oral, intravenous, topical, and parenteral administration routes. The book also discusses safety aspects of drugs and excipients, as well as regulatory issues relevant to formulation. Innovative Dosage Forms: Design and Development at Early Stage starts with a look at the impact of the polymorphic form of drugs on the preformulation and formulation development. It then offers readers reliable strategies for the formulation development of poorly soluble drugs. The book also studies the role of reactive impurities from the excipients on the formulation shelf life; preclinical formulation assessment of new chemical entities; and regulatory aspects for formulation design. Other chapters cover innovative formulations for special indications, including oncology injectables, delayed release and depot formulations; accessing pharmacokinetics of various dosage forms; physical characterization techniques to assess amorphous nature; novel formulations for protein oral dosage; and more. -Provides information that is essential for the drug development effort -Presents the latest advances in the field and describes in detail innovative formulations, such as nanosuspensions, micelles, and cocrystals -Describes current approaches in early pre-formulation to achieve the best in vivo results -Addresses regulatory and safety aspects, which are key considerations for pharmaceutical companies -Includes case studies from recent drug development programs to illustrate the practical challenges of preformulation design Innovative Dosage Forms: Design and Development at Early Stage provides valuable benefits to interdisciplinary drug discovery teams working in industry and academia and will appeal to medicinal chemists, pharmaceutical chemists, and pharmacologists.

Physics Briefs

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Publisher :
ISBN 13 :
Total Pages : 826 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Physics Briefs by :

Download or read book Physics Briefs written by and published by . This book was released on 1991 with total page 826 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Crystallization

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Publisher : BoD – Books on Demand
ISBN 13 : 9535107577
Total Pages : 582 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Crystallization by : Marcello Andreeta

Download or read book Crystallization written by Marcello Andreeta and published by BoD – Books on Demand. This book was released on 2012-09-19 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt: Crystallization is one of the most ancient and interdisciplinary topics of research known to mankind. Crystals can be organic or inorganic and may be produced from melts, liquid solutions, vapors or even in solid state. Notwithstanding its inherently high complexity, the crystallization process is part of our everyday lives, from ice making in our homes to the most state-of-the-art chemical and electronic industry. In this book, our purpose was to present new insights to the reader, as well as crucial and very useful information for researchers working in this field, while simultaneously creating a comprehensive text about crystallization processes which may serve as a starting point for people with different backgrounds.

Handbook of Solvents, Volume 1

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Publisher : Elsevier
ISBN 13 : 1774670410
Total Pages : 997 pages
Book Rating : 4.7/5 (746 download)

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Book Synopsis Handbook of Solvents, Volume 1 by : George Wypych

Download or read book Handbook of Solvents, Volume 1 written by George Wypych and published by Elsevier. This book was released on 2024-02-07 with total page 997 pages. Available in PDF, EPUB and Kindle. Book excerpt: This 4th edition of Handbook of Solvents, Volume 1, contains the most recent findings and trends in solvent applications. It is a comprehensive survey of the science of solvents and their properties, covering all aspects of solvent behavior that are relevant to their use in chemical and related industries including agricultural and technical processes, inorganic synthesis and materials chemistry, and more. Divided into two volumes, this first volume covers high-level information on the physical chemical properties of the most relevant solvent systems. Each chapter is focused on a specific aspect of solvent properties that determine its selection, such as the effect on properties of solutes and solutions, properties of different groups of solvents, and the summary of their applications' effect on health and the environment (given in tabulated form). Also covered is swelling of solids in solvents, solvent diffusion and drying processes, nature of the interaction of solvent and solute in solutions, acid-base interactions, the effect of solvents on spectral and other electronic properties of solutions, the effect of solvents on the rheology of the solution, aggregation of solutes, permeability, molecular structure, crystallinity, configuration, conformation of dissolved high molecular weight compounds, and the effect of solvents on chemical reactions and reactivity of dissolved substances. With insight from specialists in a broad array of different areas and written with an interdisciplinary audience in mind, this thoroughly revised 4th edition provides readers with a complete overview of all the organic solvents available for industrial applications today. The book contains numerous references to key sources of more detailed information, and together with Handbook of Solvents Volume 2: Use, Health, and Environment; Databook of Green Solvents; and Databook of Solvents, represents the most comprehensive and up-to-date information ever published on solvents. - Provides key insights that will help engineers and scientists select the best solvent for the job - Includes practical information and ideas on how to improve existing processes involving solvents - Presents the latest advances in solvent technology and their applications

Energy Research Abstracts

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Publisher :
ISBN 13 :
Total Pages : 1162 pages
Book Rating : 4.3/5 (129 download)

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Book Synopsis Energy Research Abstracts by :

Download or read book Energy Research Abstracts written by and published by . This book was released on 1977 with total page 1162 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Static Compression of Energetic Materials

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Publisher : Springer Science & Business Media
ISBN 13 : 3540681515
Total Pages : 340 pages
Book Rating : 4.5/5 (46 download)

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Book Synopsis Static Compression of Energetic Materials by : Suhithi M. Peiris

Download or read book Static Compression of Energetic Materials written by Suhithi M. Peiris and published by Springer Science & Business Media. This book was released on 2009-01-03 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developing and testing novel energetic materials is an expanding branch of the materials sciences. Reaction, detonation or explosion of such materials invariably produce extremely high pressures and temperatures. To study the equations-of-state (EOS) of energetic materials in extreme regimes both shock and static high pressure studies are required. The present volume is an introduction and review of theoretical, experimental and numerical aspects of static compression of such materials. Chapter 1 introduces the basic experimental tool, the diamond anvil pressure cell and the observational techniques used with it such as optical microscopy, infrared spectrometry and x-ray diffraction. Chapter 2 outlines the principles of high-nitrogen energetic materials synthesis. Chapters 3 and 4, examine and compare various EOS formalisms and data fitting for crystalline and non-crystalline materials, respectively. Chapter 5 details the reaction kinetics of detonating energetic materials. Chapter 6 investigates the interplay between static and dynamic (shock) studies. Finally, Chapters 7 and 8 introduce numerical simulations: molecular dynamics of energetic materials under either hydrostatic or uni-axial stress and ab-inito treatments of defects in crystalline materials. This timely volume meets the growing demand for a state-of-the art introduction and review of the most relevant aspects of static compression of energetic materials and will be a valuable reference to researchers and scientists working in academic, industrial and governmental research laboratories.

Polymorphism in Molecular Crystals

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Publisher : Oxford University Press
ISBN 13 : 0198506058
Total Pages : 429 pages
Book Rating : 4.1/5 (985 download)

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Book Synopsis Polymorphism in Molecular Crystals by : Joel Bernstein

Download or read book Polymorphism in Molecular Crystals written by Joel Bernstein and published by Oxford University Press. This book was released on 2002 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymorphism - the multiplicity of structures or forms - is a term that is used in many disciplines. In chemistry it refers to the existence of more than one crystal structure for a particular chemical substance. The properties of a substance are determined by its composition and by its structure. In the last two decades, there has been a sharp rise in the interest in polymorphic systems, as an intrinsically interesting phenomenon and as an increasingly important component in the development and marketing of a variety of materials based on organic molecules (e.g. pharmaceuticals, dyes and pigments, explosives, etc.). This book summarizes and brings up to date the current knowledge and understanding of polymorphism of molecular crystals, and concentrates it in one comprehensive source. The book will be an invaluable reference for students, researchers, and professionals in the field.

High-pressure Research

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Publisher : American Geophysical Union
ISBN 13 : 0875900348
Total Pages : 501 pages
Book Rating : 4.8/5 (759 download)

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Book Synopsis High-pressure Research by : Yasuhiko Syono

Download or read book High-pressure Research written by Yasuhiko Syono and published by American Geophysical Union. This book was released on 1992 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Intrinsic Structures and Properties of Energetic Materials

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Publisher : Springer Nature
ISBN 13 : 9819926998
Total Pages : 469 pages
Book Rating : 4.8/5 (199 download)

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Book Synopsis Intrinsic Structures and Properties of Energetic Materials by : Chaoyang Zhang

Download or read book Intrinsic Structures and Properties of Energetic Materials written by Chaoyang Zhang and published by Springer Nature. This book was released on 2023-06-30 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the intrinsic structures of all kinds of energetic compounds and some structure–property relationships therein. Energetic materials are a class of energy materials that can transiently release a large amount of gases and heat by self-redox after stimulated and usually refer to explosives, propellants and pyrotechnics. Nowadays, in combination with various theories and simulation-aided material design technologies, many new kinds of energetic materials like energetic extended solids, energetic ionic salts, energetic metal organic frames, energetic co-crystals and energetic perovskites have been created, in addition to traditional energetic molecular crystals. It is somewhat dazzling, and an issue of how we can understand these new types of energetic materials is raised. In the past about 20 years, we were immersed in the computational energetic materials. By means of defining a concept of intrinsic structures of energetic materials, which refers to the crystal packing structure of energetic materials, as well as molecule for molecular solid specially, the microscopic structures have been mostly clarified, and related with many macroscopic properties and performances, with molecular simulations. This book presents our understanding about it. Thereby, a simply and new way to readily understand energetic materials is expected to be paved, based on this book. It contains energetic molecular crystals, energetic ionic crystals, energetic atomic crystals, energetic metallic crystals and energetic mixed-type crystals and the substructures closest to crystal packing. Meanwhile, the common intermolecular interactions in energetic crystals will be introduced. In addition, theoretical and simulation methods for treating the intrinsic structures will be briefed, as they are the main tools to reveal the molecules and crystals. Besides, the polymorphism as a level of intrinsic structures will be briefly discussed. In the final of this book, we introduce the crystal engineering of energetic materials. This book features the first proposal of intrinsic structure and crystal engineering of energetic materials and the understanding of the properties and performances of energetic materials by maintaining a concept that structure determines property. It helps to promote the rationality in creating new energetic materials, rather than increase experience.

Shock Waves

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Publisher : Springer Science & Business Media
ISBN 13 : 3642776485
Total Pages : 735 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Shock Waves by : Kazuyoshi Takayama

Download or read book Shock Waves written by Kazuyoshi Takayama and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 735 pages. Available in PDF, EPUB and Kindle. Book excerpt: Shock wave research covers important inderdisciplinary areas which range from basic topics on gasdynamics, combustion and detonation, physico-chemistry of high temperature gases, plasma physics, astro and geophysics, materials science, astronautics and space technology to medical and industrial applications. This book includes 202 papers presented at the 18th the International Symposium on Shock Waves which describe the research frontier of shock wave phenopmena and 14 plenary lectures which show the state of the art of various fields of shock wave research. This proceedings is a unique collection of most important and updated shock wave research.

British National Bibliography for Report Literature

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Publisher :
ISBN 13 :
Total Pages : 806 pages
Book Rating : 4.:/5 (334 download)

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Book Synopsis British National Bibliography for Report Literature by :

Download or read book British National Bibliography for Report Literature written by and published by . This book was released on 2001 with total page 806 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Discovering and Developing Molecules with Optimal Drug-Like Properties

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Publisher : Springer
ISBN 13 : 1493913999
Total Pages : 510 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Discovering and Developing Molecules with Optimal Drug-Like Properties by : Allen C Templeton

Download or read book Discovering and Developing Molecules with Optimal Drug-Like Properties written by Allen C Templeton and published by Springer. This book was released on 2014-10-31 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: This authoritative volume provides a contemporary view on the latest research in molecules with optimal drug-like properties. It is a valuable source to access current best practices as well as new research techniques and strategies. Written by leading scientists in their fields, the text consists of fourteen chapters with an underlying theme of early collaborative opportunities between pharmaceutical and discovery sciences. The book explores the practical realities of performing physical pharmaceutical and biopharmaceutical research in the context of drug discovery with short timelines and low compound availability. Chapters cover strategies and tactics to enable discovery as well as predictive approaches to establish, understand and communicate risks in early development. It also examines the detection, characterization, and assessment of risks on the solid state properties of advanced discovery and early development candidates, highlighting the link between solid state properties and critical development parameters such as solubility and stability. Final chapters center on techniques to improve molecular solubilization and prevent precipitation, with particularly emphasis on linking physiochemical properties of molecules to formulation selection in preclinical and clinical settings.

Disordered Materials

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Publisher : Alpha Science Int'l Ltd.
ISBN 13 : 9788173194634
Total Pages : 292 pages
Book Rating : 4.1/5 (946 download)

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Book Synopsis Disordered Materials by : S. K. Tripathi

Download or read book Disordered Materials written by S. K. Tripathi and published by Alpha Science Int'l Ltd.. This book was released on 2003 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the National Conference on "Recent Developments on Disordered Materials", held in Dept. of Physics, Panjab University, Chandigarh, on 15-16 March, 2001; contributed papers.

Catalog of National Bureau of Standards Publications, 1966-1976

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Publisher :
ISBN 13 :
Total Pages : 844 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Catalog of National Bureau of Standards Publications, 1966-1976 by : United States. National Bureau of Standards. Technical Information and Publications Division

Download or read book Catalog of National Bureau of Standards Publications, 1966-1976 written by United States. National Bureau of Standards. Technical Information and Publications Division and published by . This book was released on 1978 with total page 844 pages. Available in PDF, EPUB and Kindle. Book excerpt: