Journal Of Analytical Toxicology

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Fundamentals of Analytical Toxicology

Author : Robert J. Flanagan
Publisher : John Wiley & Sons
ISBN 13 : 0470319348
Total Pages : 605 pages
Book Rating : 4.4/5 (73 download)

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Book Synopsis Fundamentals of Analytical Toxicology by : Robert J. Flanagan

Download or read book Fundamentals of Analytical Toxicology written by Robert J. Flanagan and published by John Wiley & Sons. This book was released on 2008-03-03 with total page 605 pages. Available in PDF, EPUB and Kindle. Book excerpt: The analytical toxicologist may be required to detect, identify, and in many cases measure a wide variety of compounds in samples from almost any part of the body or in related materials such as residues in syringes or in soil. This book gives principles and practical information on the analysis of drugs and poisons in biological specimens, particularly clinical and forensic specimens. After providing some background information the book covers aspects of sample collection, transport, storage and disposal, and sample preparation. Analytical techniques - colour tests and spectrophotometry, chromatography and electrophoresis, mass spectrometry, and immunoassay – are covered in depth, and a chapter is devoted to the analysis of trace elements and toxic metals. General aspects of method implementation/validation and laboratory operation are detailed, as is the role of the toxicology laboratory in validating and monitoring the performance of point of care testing (POCT) devices. The book concludes with reviews of xenobiotic absorption, distribution and metabolism, pharmacokinetics, and general aspects of the interpretation of analytical toxicology results. A clearly written, practical, integrated approach to the basics of analytical toxicology. Focuses on analytical, statistical and pharmacokinetic principles rather than detailed applications. Assumes only a basic knowledge of analytical chemistry. An accompanying website provides additional material and links to related sites. Written by an experienced team of authors,Fundamentals of Analytical Toxicology is an invaluable resource for those starting out in a career in analytical toxicology across a wide range of disciplines including clinical and forensic science, food safety, and pharmaceutical development. Praise from the reviews: “This is an ambitious effort to describe in detail the many and varied aspects of the science of toxicological analysis. The 17 chapters cover every foreseeable aspect, from specimen collection through analytical techniques and quality control to pharmacological principles and interpretation of results. The authors bring together a great deal of experience in the field and have succeeded admirably in achieving their goal: "to give principles and practical information on the analysis of drugs, poisons and other relevant analytes in biological specimens...". The book is very readable and quite up-to-date, and contains many illustrative figures, charts and tables. Both the student and the practicing professional would do well to study this material carefully, as there is something here for every conceivable level of interest.” Review from Randall Baselt "This text comes highly recommended for any analytical toxicology trainee." The Bulletin of the Royal College of Pathologists “Overall, this book provides a comprehensive, thorough, clear, up to date and practical treatment of analytical toxicology at a high standard. Understanding of the text is enhanced by the use of many illustrations. Specifications, guidelines, and methods are highlighted in grey background “Boxes”. The many and up to date literature references in each chapter demonstrate the authors’ thorough work and permit easy access to deeper information. Therefore this book can be highly recommended as a valuable source of knowledge in analytical toxicology both as an introduction and for the advanced reader.” GTFCh Bulletin “Toxichem + Krimtech”, May 2008 (translated, original review in German) “Many toxicologists will add this important reference to their libraries because it competently fills a need ...” International Journal of Toxicology “The book is very well illustrated, easy to understand and pleasant to read, and contains a wealth of dedicated information.” International Journal of Environmental Analytical Chemistry

Principles of Forensic Toxicology

Author : Barry Levine
Publisher : Amer. Assoc. for Clinical Chemistry
ISBN 13 : 9781890883874
Total Pages : 406 pages
Book Rating : 4.8/5 (838 download)

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Book Synopsis Principles of Forensic Toxicology by : Barry Levine

Download or read book Principles of Forensic Toxicology written by Barry Levine and published by Amer. Assoc. for Clinical Chemistry. This book was released on 2003 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt:

New Psychoactive Substances

Author : Hans H. Maurer
Publisher : Springer
ISBN 13 : 303010561X
Total Pages : 563 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis New Psychoactive Substances by : Hans H. Maurer

Download or read book New Psychoactive Substances written by Hans H. Maurer and published by Springer. This book was released on 2019-02-20 with total page 563 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is designed to feature the pharmacology of new psychoactive substances, legislative aspects, information exchange including epidemiology, and clinical, forensic, and analytical toxicology in order to facilitate the understanding of this complex and rapidly developing phenomenon.

Clarke's Analytical Forensic Toxicology

Author : Gail Cooper
Publisher : Pharmaceutical Press
ISBN 13 : 0857110543
Total Pages : 657 pages
Book Rating : 4.8/5 (571 download)

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Book Synopsis Clarke's Analytical Forensic Toxicology by : Gail Cooper

Download or read book Clarke's Analytical Forensic Toxicology written by Gail Cooper and published by Pharmaceutical Press. This book was released on 2013-05-28 with total page 657 pages. Available in PDF, EPUB and Kindle. Book excerpt: This invaluable textbook, written by international experts, covers all the main elements of forensic toxicology and analytical toxicology techniques as well as the important parts of pharmacokinetics, drug metabolism, and pharmacology in general, with a particular focus on drugs of abuse.

Drug Monitoring and Clinical Chemistry

Author : Georg Hempel
Publisher : Elsevier
ISBN 13 : 0080530540
Total Pages : 379 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Drug Monitoring and Clinical Chemistry by : Georg Hempel

Download or read book Drug Monitoring and Clinical Chemistry written by Georg Hempel and published by Elsevier. This book was released on 2004-05-15 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Monitoring and Clinical Chemistry, the 5th volume in the Handbook of Analytical Separations series, gives an overview about methods to analyse drugs in biological fluids. The most widely used methods to analyse drugs in biological fluids. i.e. chromatographic methods, CE and immunoassays are described in detail. For important drugs, an overview about the methods available and a comparison of the techniques should be given to enable the reader to choose the right method depending on laboratory equipment, staff, the aim of the investigation etc. Other general aspects important for conducting therapeutic drug monitoring or pharmacokinetics studies are also covered, i.e. sample preparation, validation of the analytical methods and pharmacokinetic methods for interpreting the data. Areas where therapeutic drug monitoring is used frequently such as antibiotics, immunosuppressant drugs, antipsychotic and anticancer drugs will be discussed in detail. In addition, the important field of phenotyping and genotyping for therapy optimisation with special focus on real-life applications is also covered. The book contains important information for analyst working on drug analysis in clinical chemistry, hospital pharmacists involved in therapeutic drug monitoring, other pharmacists, chemists or physicians working on pharmacokinetic studies in industry or academia. In contrast to other books in this field, this book provides up-to-date information regarding both methodology and clinical applications. For the applications, only fields are described where therapeutic drug monitoring is used in clinical routine and provides benefit to the patients. - Overview of all important field where therapeutic drug monitoring is applied - All relevant analytical and computational methods are discussed - Written by experts with a lot of practical experience in the field

Food Toxicants Analysis

Author : Yolanda Picó
Publisher : Elsevier
ISBN 13 : 0080468012
Total Pages : 787 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Food Toxicants Analysis by : Yolanda Picó

Download or read book Food Toxicants Analysis written by Yolanda Picó and published by Elsevier. This book was released on 2007-02-07 with total page 787 pages. Available in PDF, EPUB and Kindle. Book excerpt: Food Toxicants Analysis covers different aspects from the field of analytical food toxicology including emerging analytical techniques and applications to detect food allergens, genetically modified organisms, and novel ingredients (including those of functional foods). Focus will be on natural toxins in food plants and animals, cancer modulating substances, microbial toxins in foods (algal, fungal, and bacterial) and all groups of contaminants (i.e., pesticides), persistent organic pollutants, metals, packaging materials, hormones and animal drug residues. The first section describes the current status of the regulatory framework, including the key principles of the EU food law, food safety, and the main mechanisms of enforcement. The second section addresses validation and quality assurance in food toxicants analysis and comprises a general discussion on the use of risk analysis in establishing priorities, the selection and quality control of available analytical techniques. The third section addresses new issues in food toxicant analysis including food allergens and genetically modified organisms (GMOs). The fourth section covers the analysis of organic food toxicants.* step-by-step guide to the use of food analysis techniques* eighteen chapters covering emerging fields in food toxicants analysis* assesses the latest techniques in the field of inorganic analysis

Molecular, Clinical and Environmental Toxicology

Author : Andreas Luch
Publisher : Springer Science & Business Media
ISBN 13 : 3764383380
Total Pages : 620 pages
Book Rating : 4.7/5 (643 download)

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Book Synopsis Molecular, Clinical and Environmental Toxicology by : Andreas Luch

Download or read book Molecular, Clinical and Environmental Toxicology written by Andreas Luch and published by Springer Science & Business Media. This book was released on 2010-03-01 with total page 620 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Toxicology is the second volume of a three-volume set on molecular, clinical and environmental toxicology that offers a comprehensive and in-depth response to the increasing importance and abundance of chemicals of daily life. By providing intriguing insights far down to the molecular level, this three-volume work covers the entire range of modern toxicology with special emphasis on recent developments and achievements. It is written for students and professionals in medicine, science, public health or engineering who are demanding reliable information on toxic or potentially harmful agents and their adverse effects on the human body.

Pediatric Clinical Pharmacology

Author : Hannsjörg W. Seyberth
Publisher : Springer Science & Business Media
ISBN 13 : 3642201954
Total Pages : 385 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Pediatric Clinical Pharmacology by : Hannsjörg W. Seyberth

Download or read book Pediatric Clinical Pharmacology written by Hannsjörg W. Seyberth and published by Springer Science & Business Media. This book was released on 2011-09-01 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: The objective of this volume is to give an overview of the present state of the art of pediatric clinical pharmacology including developmental physiology, pediatric-specific pathology, special tools and methods for development of drugs for children (assessment of efficacy, toxicity, long-term safety etc.) as well as regulatory and ethical knowledge and skills. In the future, structural and educational changes have to lead back to a closer cooperation and interaction of pediatrics with (clinical) pharmacology and pharmacy.

Fundamentals of Toxicology

Author : PK Gupta
Publisher : Academic Press
ISBN 13 : 0128054034
Total Pages : 424 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Fundamentals of Toxicology by : PK Gupta

Download or read book Fundamentals of Toxicology written by PK Gupta and published by Academic Press. This book was released on 2016-08-26 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals of Toxicology: Essential Concepts and Applications provides a crisp, easy-to-understand overview of the most important concepts, applications, and ideas needed to learn the basics of toxicology. Written by a pre-eminent toxicologist with over five decades of teaching experience, this comprehensive resource offers the hands-on knowledge needed for a strong foundation in the wide field of toxicology. Fundamentals of Toxicology includes a clear structure divided into five units to assist learning and understanding. The first unit provides extensive coverage on the background of toxicology including commonly used definitions and historical perspective, while following units cover: basic concepts; regulatory requirements and good laboratory practices, including types of toxicology testing and evaluation; toxic agents and adverse effects on health; and analytical, forensic, and diagnostic toxicology. This is an essential book for advanced students in toxicology and across the biomedical sciences, life sciences, and environmental sciences who want to learn the concepts of toxicology, as well as early researchers needing to refresh outside of their specialty. - Explains the essential concepts of toxicology in a clear fashion - Provides in-depth coverage of testing protocols, common drugs, chemicals, and laboratory-based diagnostic and analytical toxicology - Explores the history, foundations, and most recent concepts of toxicology - Serves as an essential reference for advanced students in toxicology and across the biomedical, life, and environmental sciences who want to learn the concepts of toxicology

Dietary Supplement Test Methods: Liquid Chromatography Separation Techniques And Application

Author : David Dajing Ji
Publisher : World Scientific
ISBN 13 : 9811249261
Total Pages : 498 pages
Book Rating : 4.8/5 (112 download)

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Book Synopsis Dietary Supplement Test Methods: Liquid Chromatography Separation Techniques And Application by : David Dajing Ji

Download or read book Dietary Supplement Test Methods: Liquid Chromatography Separation Techniques And Application written by David Dajing Ji and published by World Scientific. This book was released on 2022-04-21 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the analytical approach to testing over 160 important dietary supplement ingredients. In addition to the methods, there is significant guidance provided on how to develop, modify, and improve testing techniques. The procedures in this book include some of the most modern technologies that are available in the laboratory today. These basic principles of method development and troubleshooting can be implemented for food and food safety testing, drug development research, and agricultural areas. The contents of this book contain a very comprehensive collection of valuable analytical tools.

Small Animal Toxicology

Author : Patricia A. Talcott
Publisher : Elsevier Health Sciences
ISBN 13 : 0323241980
Total Pages : 955 pages
Book Rating : 4.3/5 (232 download)

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Book Synopsis Small Animal Toxicology by : Patricia A. Talcott

Download or read book Small Animal Toxicology written by Patricia A. Talcott and published by Elsevier Health Sciences. This book was released on 2012-12-03 with total page 955 pages. Available in PDF, EPUB and Kindle. Book excerpt: - 20 new chapters have been added - New topics include a list of toxicants affecting body systems, management of toxins in pregnancy, diagnostic toxicology, bacterial toxins, and cosmetic/toilet articles - Snake-bite injuries are treated in two separate, expanded chapters: Pit Vipers and Coral Snakes - Section on pharmaceuticals includes bromides, anticonvulsants, tricycle antidepressants, monoamine oxidize inhibitors, B-adrenergic toxicities, and vitamins A and D - Additional specific toxicants are covered, including Amitraz, hydramethylon, ethanol, mercury, toad toxins, poisonous frogs, salamanders, newts and venomous arthropods•Additional specific toxicants are covered, including Amitraz, hydramethylon, ethanol, mercury, toad toxins, poisonous frogs, salamanders, newts and venomous arthropods.

Clarke's Analysis of Drugs and Poisons

Author : A. C. Moffat
Publisher :
ISBN 13 :
Total Pages : 680 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Clarke's Analysis of Drugs and Poisons by : A. C. Moffat

Download or read book Clarke's Analysis of Drugs and Poisons written by A. C. Moffat and published by . This book was released on 2004 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: This manual and reference work provides a source of analytical data for drugs and related substances. It is intended for scientists faced with the difficult problem of identifying a drug in a pharmaceutical product, in a sample of tissue or body fluid, from a living patient or in post-mortem material. Volume One contains 32 chapters covering the practice of and analytical procedures used in forensic toxicology. Volume Two contains over 1750 drug and related substance monographs detailing: physical properties; analytical methods; pharmacokinetic data; and toxicity data, as well as expanded indexes and appendices. These volumes should be useful for all forensic and crime laboratories, toxicologists and analytical chemists, pathologists, poison information centres and clinical pharmacology departments.

Medical Toxicology of Drug Abuse

Author : Donald G. Barceloux
Publisher : John Wiley & Sons
ISBN 13 : 1118106059
Total Pages : 1080 pages
Book Rating : 4.1/5 (181 download)

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Book Synopsis Medical Toxicology of Drug Abuse by : Donald G. Barceloux

Download or read book Medical Toxicology of Drug Abuse written by Donald G. Barceloux and published by John Wiley & Sons. This book was released on 2012-02-03 with total page 1080 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a broad reference covering important drugs of abuse including amphetamines, opiates, and steroids. It also covers psychoactive plants such as caffeine, peyote, and psilocybin. It provides chemical structures, analytical methods, clinical features, and treatments of these drugs of abuse, serving as a highly useful, in-depth supplement to a general medical toxicology book. The style allows for the easy application of the contents to searchable databases and other electronic products, making this an essential resource for practitioners in medical toxicology, industrial hygiene, occupational medicine, pharmaceuticals, environmental organizations, pathology, and related fields.

Forensic Toxicology

Author : Nicholas T. Lappas
Publisher : Academic Press
ISBN 13 : 0128192879
Total Pages : 545 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Forensic Toxicology by : Nicholas T. Lappas

Download or read book Forensic Toxicology written by Nicholas T. Lappas and published by Academic Press. This book was released on 2021-10-22 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: **Selected for Doody's Core Titles® 2024 in Toxicology**The second edition of Forensic Toxicology: Principles and Concepts takes the reader back to the origins of forensic toxicology providing an overview of the largely unchanging principles of the discipline. The text focuses on the major tenets in forensic toxicology, including an introduction to the discipline, principles of forensic toxicology including pharmacokinetics, pharmacodynamics, drug interactions and toxicogenomics, fundamentals of forensic toxicology analysis, types of interpretations based on analytical forensic toxicology results, and reporting from the laboratory to the courtroom. Also included in the second edition is a Unit focused on the forensic toxicology of individual drugs of abuse. - Includes significant emphasis on the fundamental principles and concepts of forensic toxicology - Provides students with an introduction to the core tenets of the discipline, focusing on the concepts, strategies, and methodologies utilized by professionals in the field - Coauthored by a forensic toxicologist with over 40 years of experience as a professor who has taught graduate courses in forensic and analytical toxicology and who has served as a consultant and expert witness in civil and criminal cases

Forensic Science

Author :
Publisher : Elsevier
ISBN 13 : 0080554253
Total Pages : 1047 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Forensic Science by :

Download or read book Forensic Science written by and published by Elsevier. This book was released on 2011-09-22 with total page 1047 pages. Available in PDF, EPUB and Kindle. Book excerpt: Forensic Science, Second Edition presents the applications of separation methods, manly chromatography, in forensic practice. The first part, devoted to forensic toxicology, contains reviews on forensic relevant groups of compounds, like: Opiate agonists, cocaine, amphetamines, hallucinogens, cannabinoids, sedatives and hypnotics, antidepressive and antipsychotic drugs, analgesics, antidiabetics, muscle relaxants, and mushroom toxins.In these parts, the preliminary immunochemical tests were also included, together with separation methods. Screening procedures used in forensic toxicology were presented in separate chapters on forensic screening with GC, GC-MS, HPLC, LC-MS, CE, and LC-ICP-MS. In the part on actual and emerging problems of forensic toxicology, following chapters were included: Analytical markers of alcohol abuse, toxicological aspects of herbal remedies, drugs and driving, analysis in alternative matrices, doping analysis, pharmacogenomics in forensic toxicology, and quality assurance. The second part presents application of separation methods in forensic chemistry, and comprises chapters on: Explosives, chemical warfare agents, arson analysis, and writing media. Third part on forensic identification contains chapter on forensic genetics.All chapters are written up-to-date and present specific information up to 2006. The authors of each chapter are known not only from their scientific activity, but are also reputed experts, proven in everyday forensic casework. - Wide spectrum of topics presented - Up-to-date presentation of topics - Data are presented in comparative mode - Special stress put on screening procedures

Drugs and Poisons in Humans

Author : Osamu Suzuki
Publisher : Springer Science & Business Media
ISBN 13 : 3540275797
Total Pages : 653 pages
Book Rating : 4.5/5 (42 download)

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Book Synopsis Drugs and Poisons in Humans by : Osamu Suzuki

Download or read book Drugs and Poisons in Humans written by Osamu Suzuki and published by Springer Science & Business Media. This book was released on 2006-01-16 with total page 653 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unique analysis of drugs and poisons to facilitate testing in all laboratories even by inexperienced chemists Includes source of chemicals needed for the experiments Texts are composed by 67 experts in analyzing the respective compounds Clear and uniform structure of chapters for ease of reading The text is illustrated by many diagrams and tables

Genotoxic Impurities

Author : Andrew Teasdale
Publisher : John Wiley & Sons
ISBN 13 : 0470934751
Total Pages : 455 pages
Book Rating : 4.4/5 (79 download)

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Book Synopsis Genotoxic Impurities by : Andrew Teasdale

Download or read book Genotoxic Impurities written by Andrew Teasdale and published by John Wiley & Sons. This book was released on 2011-03-29 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines genotoxic impurities and their impact on the pharmaceutical industry. Specific sections examine this from both a toxicological and analytical perspective. Within these sections, the book defines appropriate strategies to both assess and ultimately control genotoxic impurities, thus aiding the reader to develop effective control measures. An opening section covers the development of guidelines and the threshold of toxicological concern (TTC) and is followed by a section on safety aspects, including safety tests in vivo and vitro, and data interpretation. The second section addresses the risk posed by genotoxic impurities from outside sources and from mutagens within DNA. In the final section, the book deals with the quality perspective of genotoxic impurities focused on two critical aspects, the first being the analysis and the second how to practically evaluate the impurities.