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Author : Viskam Wijewardana
Publisher : Frontiers Media SA
ISBN 13 : 2832515479
Total Pages : 187 pages
Book Rating : 4.8/5 (325 download)
Download or read book Irradiation technologies for vaccine development written by Viskam Wijewardana and published by Frontiers Media SA. This book was released on 2023-02-27 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Sarat K. Dalai
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (139 download)
Download or read book Application of Radiation Technology written by Sarat K. Dalai and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Among the numerous infectious diseases, malaria remains a major health challenge. Despite the various approaches adopted for the vector control and availability of antimalarial drugs, the success of malaria eradication is dampened by the spread of drug and insecticide resistance, unavailability of proper diagnostic treatment and successful vaccine. Among the various approaches, vaccination with the aim of developing protective immunity is the most suited, safe and reliable approach for the entire mankind. Numerous approaches are in use for vaccine development; however, they suffer from the drawbacks that immunity developed is short lived and are both species- and stage-specific. Of late, radiation sterilization has drawn the attention in the vaccine development due to its advantages over the conventional methods, and successful clinical trials of irradiated vaccines against the pathogens and tumor. Recently, a novel approach of genetically attenuated sporozoites (PfRAS, PfSPZ, PFSPZ-GA1 sporozoites vaccines) has shown promising results by generating protective immunity against the homologous and heterogenous infection in the clinical trials. Radiation techniques have also been beneficial in controlling the insects by sterility technique. In this chapter, we have recapitulated the role of radiation biology in the malaria vaccine development with its current status and future challenges associated with the development of radiation attenuated parasite vaccine.
Author : Shima Shayanfar
Publisher : John Wiley & Sons
ISBN 13 : 1119488575
Total Pages : 292 pages
Book Rating : 4.1/5 (194 download)
Download or read book Ionizing Radiation Technologies written by Shima Shayanfar and published by John Wiley & Sons. This book was released on 2022-08-02 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ionizing Radiation Technologies An authoritative overview of major advances in the application of ionizing radiation technologies to industrial, agricultural, and municipal waste products In Ionizing Radiation Technologies: Managing and Extracting Value from Wastes, a team of expert researchers delivers a broad overview of the value trapped in waste streams and how a strategic application of ionizing radiation technologies can be valuable from both an environmental and an economic perspective. A valuable addition to the discussions around sustainability and green technologies, the book introduces ionizing radiation technologies, including gamma (cobalt-60) irradiation and high and low energy electron beam technologies. The contributions included explore the major advances taking place in the application of ionizing radiation technologies to derive high value end-products from agricultural, municipal, and industrial wastes. Each chapter reviews original research and data and considers likely future directions in research and development. The book also includes: A thorough introduction to the application of ionizing radiation technologies to agricultural waste, including the production of activated carbon Comprehensive explorations of the application of ionizing radiation technologies to municipal waste, including municipal solid wastes and recycling wastewater Practical discussions of the application of ionizing radiation technologies to industrial waste, including textile wastewater management and polymer recycling In-depth examinations of the economics of waste valorization, including several case studies of businesses involved in waste valorization Perfect for consulting engineers and industry professionals involved in waste management and mitigation, Ionizing Radiation Technologies will also earn a place in the libraries of professionals at government agencies, international food organizations, and NGOs focused on waste management, environment sustainability, and urban planning.
Author : Otolorin Adelaja Osibote
Publisher :
ISBN 13 : 9781789841428
Total Pages : 204 pages
Book Rating : 4.8/5 (414 download)
Download or read book Ionizing and Non-ionizing Radiation written by Otolorin Adelaja Osibote and published by . This book was released on 2020 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides readers with comprehensive details on the management and measures to protect health against risks to people and environments generated by the use of ionizing and non-ionizing radiation. This book is divided into three sections, namely, Radiation Protection and Measurement; Radiation Therapy; and Radioactivity. The first section covers ionizing radiation protection; population exposure to non-ionizing density; and the system of dosimetry quantities for use in emergency preparedness and response to nuclear or radiological accidents. The second section covers various planning techniques for spinal stereotactic body radiotherapy and the application of radiation technology in the development of a malaria vaccine. The third section discusses environmental radioactivity monitoring using efficient measurements and the assessment of radiation exposure to humans. Also in this section is the evaluation of the effects of chronic radiation exposure on the testes of mice after a nuclear power plant accident.
Author : Igor S Lukashevich
Publisher : Springer
ISBN 13 : 3709118182
Total Pages : 393 pages
Book Rating : 4.7/5 (91 download)
Download or read book Novel Technologies for Vaccine Development written by Igor S Lukashevich and published by Springer. This book was released on 2014-11-13 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a detailed overview of the development of new viral vector-based vaccines before discussing two major applications: preventive vaccines for infectious diseases and therapeutic cancer vaccines. Viral vector-based vaccines hold a great potential for development into successful pharmaceutical products and several examples at the advanced pre-clinical or clinical stage are presented. Nevertheless, the most efforts were focused on novel and very innovative technologies for new generation of vector-based vaccines. Furthermore, specific topics such as delivery and adjuvant and protection strategies for cell-mediated-based vaccines are presented. Given its scope, the book is a “must read” for all those involved in vaccine development, both in academia and industrial vaccine development.
Author : Satoshi Ohtake
Publisher : John Wiley & Sons
ISBN 13 : 3527341129
Total Pages : 394 pages
Book Rating : 4.5/5 (273 download)
Download or read book Drying Technologies for Biotechnology and Pharmaceutical Applications written by Satoshi Ohtake and published by John Wiley & Sons. This book was released on 2020-06-02 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive source of information about modern drying technologies that uniquely focus on the processing of pharmaceuticals and biologicals Drying technologies are an indispensable production step in the pharmaceutical industry and the knowledge of drying technologies and applications is absolutely essential for current drug product development. This book focuses on the application of various drying technologies to the processing of pharmaceuticals and biologicals. It offers a complete overview of innovative as well as standard drying technologies, and addresses the issues of why drying is required and what the critical considerations are for implementing this process operation during drug product development. Drying Technologies for Biotechnology and Pharmaceutical Applications discusses the state-of-the-art of established drying technologies like freeze- and spray- drying and highlights limitations that need to be overcome to achieve the future state of pharmaceutical manufacturing. The book also describes promising next generation drying technologies, which are currently used in fields outside of pharmaceuticals, and how they can be implemented and adapted for future use in the pharmaceutical industry. In addition, it deals with the generation of synergistic effects (e.g. by applying process analytical technology) and provides an outlook toward future developments. -Presents a full technical overview of well established standard drying methods alongside various other drying technologies, possible improvements, limitations, synergies, and future directions -Outlines different drying technologies from an application-oriented point of view and with consideration of real world challenges in the field of drug product development -Edited by renowned experts from the pharmaceutical industry and assembled by leading experts from industry and academia Drying Technologies for Biotechnology and Pharmaceutical Applications is an important book for pharma engineers, process engineers, chemical engineers, and others who work in related industries.
Author : Daan J. A. Crommelin
Publisher : CRC Press
ISBN 13 : 9780415285018
Total Pages : 456 pages
Book Rating : 4.2/5 (85 download)
Download or read book Pharmaceutical Biotechnology written by Daan J. A. Crommelin and published by CRC Press. This book was released on 2002-11-14 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of pharmaceutical biotechnology is evolving rapidly. A whole new arsenal of protein pharmaceuticals is being produced by recombinant techniques for cancer, viral infections, cardiovascular and hereditary disorders, and other diseases. In addition, scientists are confronted with new technologies such as polymerase chain reactions, combinatorial chemistry and gene therapy. This introductory textbook provides extensive coverage of both the basic science and the applications of biotechnology-produced pharmaceuticals, with special emphasis on their clinical use. Pharmaceutical Biotechnology serves as a complete one-stop source for undergraduate pharmacists, and it is valuable for researchers and professionals in the pharmaceutical industry as well.
Author :
Publisher : IAEA
ISBN 13 :
Total Pages : 471 pages
Book Rating : 4./5 ( download)
Download or read book ICARST 2017 International Conference on Applications of Radiation Science and Technology written by and published by IAEA. This book was released on 2017-04-24 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 9780309045278
Total Pages : 312 pages
Book Rating : 4.0/5 (452 download)
Download or read book Malaria written by Institute of Medicine and published by National Academies Press. This book was released on 1991-02-01 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Malaria is making a dramatic comeback in the world. The disease is the foremost health challenge in Africa south of the Sahara, and people traveling to malarious areas are at increased risk of malaria-related sickness and death. This book examines the prospects for bringing malaria under control, with specific recommendations for U.S. policy, directions for research and program funding, and appropriate roles for federal and international agencies and the medical and public health communities. The volume reports on the current status of malaria research, prevention, and control efforts worldwide. The authors present study results and commentary on the: Nature, clinical manifestations, diagnosis, and epidemiology of malaria. Biology of the malaria parasite and its vector. Prospects for developing malaria vaccines and improved treatments. Economic, social, and behavioral factors in malaria control.
Author : Adelaja Osibote
Publisher : BoD – Books on Demand
ISBN 13 : 1789841410
Total Pages : 206 pages
Book Rating : 4.7/5 (898 download)
Download or read book Ionizing and Non-ionizing Radiation written by Adelaja Osibote and published by BoD – Books on Demand. This book was released on 2020-01-15 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides readers with comprehensive details on the management and measures to protect health against risks to people and environments generated by the use of ionizing and non-ionizing radiation. This book is divided into three sections, namely, Radiation Protection and Measurement; Radiation Therapy; and Radioactivity. The first section covers ionizing radiation protection; population exposure to non-ionizing density; and the system of dosimetry quantities for use in emergency preparedness and response to nuclear or radiological accidents. The second section covers various planning techniques for spinal stereotactic body radiotherapy and the application of radiation technology in the development of a malaria vaccine. The third section discusses environmental radioactivity monitoring using efficient measurements and the assessment of radiation exposure to humans. Also in this section is the evaluation of the effects of chronic radiation exposure on the testes of mice after a nuclear power plant accident.
Author :
Publisher :
ISBN 13 :
Total Pages : 926 pages
Book Rating : 4.E/5 ( download)
Download or read book Isotopes and Radiation Technology written by and published by . This book was released on 1965 with total page 926 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Fadil Bidmos
Publisher : Humana
ISBN 13 : 9781071619025
Total Pages : 0 pages
Book Rating : 4.6/5 (19 download)
Download or read book Bacterial Vaccines written by Fadil Bidmos and published by Humana. This book was released on 2022-12-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The importance of vaccines to combat bacterial diseases cannot be overstated. Methods used in the development and testing of these vaccines are evolving rapidly as a direct consequence of the availability of advanced technologies. This volume will cover methods developed in the last decade, the usage of which are enabling the development of cheaper, cost-effective and structurally stable vaccines for global use. Chapters cover in silico analytical methods such as reverse vaccinology and machine learning; low-energy electron irradiation for the generation of inactivated bacterial vaccines; methods for assessment of OMV/GMMA quality and stability; and controlled human infection models. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Bacterial Vaccines: Methods and Protocols is a valuable resource for novice and expert researchers interested in learning more about this important and constantly evolving field.
Author : Barry R. Bloom
Publisher : Academic Press
ISBN 13 : 012805400X
Total Pages : 666 pages
Book Rating : 4.1/5 (28 download)
Download or read book The Vaccine Book written by Barry R. Bloom and published by Academic Press. This book was released on 2016-06-23 with total page 666 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Vaccine Book, Second Edition provides comprehensive information on the current and future state of vaccines. It reveals the scientific opportunities and potential impact of vaccines, including economic and ethical challenges, problems encountered when producing vaccines, how clinical vaccine trials are designed, and how to introduce vaccines into widespread use. Although vaccines are now available for many diseases, there are still challenges ahead for major diseases, such as AIDS, tuberculosis, and malaria. This book is designed for students, researchers, public health officials, and all others interested in increasing their understanding of vaccines. It answers common questions regarding the use of vaccines in the context of a rapidly expanding anti-vaccine environment. This new edition is completely updated and revised with new and unique topics, including new vaccines, problems of declining immunization rates, trust in vaccines, the vaccine hesitancy, and the social value of vaccines for the community vs. the individual child’s risk. Provides insights into diseases that could be prevented, along with the challenges facing research scientists in the world of vaccines Gives new ideas about future vaccines and concepts Introduces new vaccines and concepts Gives ideas about challenges facing public and private industrial investors in the vaccine area Discusses the problem of declining immunization rates and vaccine hesitancy
Author : Brian K. Nunnally
Publisher : Springer
ISBN 13 : 3662450240
Total Pages : 669 pages
Book Rating : 4.6/5 (624 download)
Download or read book Vaccine Analysis: Strategies, Principles, and Control written by Brian K. Nunnally and published by Springer. This book was released on 2014-11-27 with total page 669 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an indispensable tool for anyone involved in the research, development, or manufacture of new or existing vaccines. It describes a wide array of analytical and quality control technologies for the diverse vaccine modalities. Topics covered include the application of both classical and modern bio-analytical tools; procedures to assure safety and control of cross contamination; consistent biological transition of vaccines from the research laboratory to manufacturing scale; whole infectious attenuated organisms, such as live-attenuated and inactivated whole-cell bacterial vaccines and antiviral vaccines using attenuated or inactivated viruses; principles of viral inactivation and the application of these principles to vaccine development; recombinant DNA approaches to produce modern prophylactic vaccines; bacterial subunit, polysaccharide and glycoconjugate vaccines; combination vaccines that contain multiple antigens as well as regulatory requirements and the hurdles of licensure.
Author : Marco Durante
Publisher : Frontiers Media SA
ISBN 13 : 2889710394
Total Pages : 728 pages
Book Rating : 4.8/5 (897 download)
Download or read book Applied Nuclear Physics at Accelerators written by Marco Durante and published by Frontiers Media SA. This book was released on 2021-07-14 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Elena Conis
Publisher : University of Chicago Press
ISBN 13 : 0226923762
Total Pages : 362 pages
Book Rating : 4.2/5 (269 download)
Download or read book Vaccine Nation written by Elena Conis and published by University of Chicago Press. This book was released on 2015 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: While vaccination rates have soared and cases of preventable infections have plummeted, an increasingly vocal cross section of Americans have questioned the safety and necessity of vaccines. In Vaccine Nation, Elena Conis explores this complicated history and its consequences for personal and public health.
Author : Walter Isaacson
Publisher : Simon and Schuster
ISBN 13 : 1982115874
Total Pages : 560 pages
Book Rating : 4.9/5 (821 download)
Download or read book The Code Breaker written by Walter Isaacson and published by Simon and Schuster. This book was released on 2021-03-09 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Best Book of 2021 by Bloomberg BusinessWeek, Time, and The Washington Post The bestselling author of Leonardo da Vinci and Steve Jobs returns with a “compelling” (The Washington Post) account of how Nobel Prize winner Jennifer Doudna and her colleagues launched a revolution that will allow us to cure diseases, fend off viruses, and have healthier babies. When Jennifer Doudna was in sixth grade, she came home one day to find that her dad had left a paperback titled The Double Helix on her bed. She put it aside, thinking it was one of those detective tales she loved. When she read it on a rainy Saturday, she discovered she was right, in a way. As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would. Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his codiscovery of the structure of DNA. She and her collaborators turned a curiosity of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code. Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids? After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020. Her story is an “enthralling detective story” (Oprah Daily) that involves the most profound wonders of nature, from the origins of life to the future of our species.
