Ionic and Volume Changes in the Microenvironment of Nerve and Receptor Cells

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Publisher : Springer Science & Business Media
ISBN 13 : 3642769373
Total Pages : 177 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Ionic and Volume Changes in the Microenvironment of Nerve and Receptor Cells by : Eva Sykova

Download or read book Ionic and Volume Changes in the Microenvironment of Nerve and Receptor Cells written by Eva Sykova and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stability of the internal environment in which neuronal elements are situated is unquestionably an important prerequisite for the effective transmission of information in the nervous system. During the past decade our knowledge on the microenvironment of nerve cells has expanded. The conception that the microenvironment of neurones comprises a fluid with a relatively simple and stable composition is no longer accepted; the microenvironment is now envisaged as a dynamic structure whose composition, shape, and volume changes, thereby significantly influencing neuronal function and the trans mission of information in the nervous system. The modern conception of the neuronal microenvironment is based on the results of research over the last 20 years. The extracellular space (ECS) is comprehended not only as a relatively stable microenvironment containing neurones and glial cells (Bernard 1878), but also as a channel for communica tion between them. The close proximity of the neuronal elements in the CNS and the narrowness of the intercellular spaces provides a basis not only for interaction between the elements themselves, but also between the elements and their microenvironment. Substances which can cross the cell membranes can easily find their way through the microenvironment to adjacent cellular elements. In this way the microenvironment can assure non-synaptic com munication between the relevant neurones. Signalization can be coded by modulation of the chemical composition of the ECS in the vicinity of the cell membrane and does not require classic connection by axones, dendrites, and synapses.

Ionic and Volume Changes in the Microenvironment of Nerve and Receptor Cells

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Publisher :
ISBN 13 :
Total Pages : 167 pages
Book Rating : 4.:/5 (262 download)

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Book Synopsis Ionic and Volume Changes in the Microenvironment of Nerve and Receptor Cells by :

Download or read book Ionic and Volume Changes in the Microenvironment of Nerve and Receptor Cells written by and published by . This book was released on 1992 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt:

PH and Brain Function

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Publisher : John Wiley & Sons
ISBN 13 : 9780471118381
Total Pages : 694 pages
Book Rating : 4.1/5 (183 download)

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Book Synopsis PH and Brain Function by : Kai Kaila

Download or read book PH and Brain Function written by Kai Kaila and published by John Wiley & Sons. This book was released on 1998-09-15 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: "PH and Brain Function offers thorough coverage of this increasingly important area of research, beginning with the fundamental concepts, which include methodological and theoretical issues such as the measurement of pH and the concept of pH in neurobiology. It explores aspects of regulation and modulation of intracellular pH in brain cells, surveys the changes in pH that occur with neural activity and how these changes affect neural activity, and discusses the role of pH in the pathophysiology of neurological diseases." "pH and Brain Function is an important resource for researchers in all areas of neuroscience as well as cell biology and physiology." --Book Jacket.

Glial Cells

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Publisher : Cambridge University Press
ISBN 13 : 9780521573689
Total Pages : 448 pages
Book Rating : 4.5/5 (736 download)

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Book Synopsis Glial Cells by : Peter R. Laming

Download or read book Glial Cells written by Peter R. Laming and published by Cambridge University Press. This book was released on 1998-06-28 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: This 1998 book discusses how neurons and glial cells interact with each other to influence behaviour.

Neuroglia

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Publisher : Oxford University Press, USA
ISBN 13 : 0199794596
Total Pages : 955 pages
Book Rating : 4.1/5 (997 download)

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Book Synopsis Neuroglia by : Helmut Kettenmann

Download or read book Neuroglia written by Helmut Kettenmann and published by Oxford University Press, USA. This book was released on 2013 with total page 955 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroglia, the third edition, is the long-awaited revision of the most highly regarded reference volume on glial cells. This indispensable edition has been completely revised, greatly enlarged, and enhanced with four-color figures throughout, all in response to the tremendous amount of new information that has accumulated since the previous edition seven years ago. Glial cells are, without doubt, the new stars in the neuroscience and neurology communities. Neglected in research for years, it is now evident that the brain only functions in a concerted action of all the cells, namely glia and neurons. Seventy one chapters comprehensively discuss virtually every aspect of normal glial cell anatomy, physiology, biochemistry and function, and consider the central roles of these cells in neurological diseases including stroke, Alzheimer disease, multiple sclerosis, Parkinson's disease, neuropathy, and psychiatric conditions. More than 20 new chapters have been added to accommodate the unprecedented growth of knowledge about the basic biology of glia and the sophisticated manner in which they partner with neurons in the course of normal brain function. Lavishly illustrated and meticulously edited, the third edition remains the most convenient and maximally useful reference available. This new edition is an essential reference for both newcomers to the field as well as established investigators. Neuroglia belongs on every neuroscientist's bookshelf and will be a great asset for educators and neurological clinicians as well.

The Neuronal Environment

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Publisher : Springer Science & Business Media
ISBN 13 : 1592591086
Total Pages : 429 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis The Neuronal Environment by : Wolfgang Walz

Download or read book The Neuronal Environment written by Wolfgang Walz and published by Springer Science & Business Media. This book was released on 2001-12-26 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading neuroscience researchers offer a fresh perspective on neuronal function by examining all its many components-including their pertubation during major disease states-and relate each element to neuronal demands. Topics range from the dependency of neurons on metabolic supply, as well as on both ion and transmitter homeostasis, to their close interaction with the myelin sheath. Also addressed are the astrocytic signaling system that controls synaptic transmission, the extracellular matrix and space as communication systems, the role of blood flow regulation in neuronal demand and in blood-brain barrier function, and inflammation and the neuroimmune system. Insightful and integrative, The Neuronal Environment: Brain Homeostasis in Health and Disease demonstrates a clear new understanding that neurons do not work in isolation, that they need constant interactions with other brain components to process information, and that they are not the only information processing system in the brain.

Astrocytes in (Patho)Physiology of the Nervous System

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Publisher : Springer Science & Business Media
ISBN 13 : 0387794921
Total Pages : 701 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Astrocytes in (Patho)Physiology of the Nervous System by : Vladimir Parpura

Download or read book Astrocytes in (Patho)Physiology of the Nervous System written by Vladimir Parpura and published by Springer Science & Business Media. This book was released on 2008-12-11 with total page 701 pages. Available in PDF, EPUB and Kindle. Book excerpt: Astrocytes were the original neuroglia that Ramón y Cajal visualized in 1913 using a gold sublimate stain. This stain targeted intermediate filaments that we now know consist mainly of glial fibrillary acidic protein, a protein used today as an astrocytic marker. Cajal described the morphological diversity of these cells with some ast- cytes surrounding neurons, while the others are intimately associated with vasculature. We start the book by discussing the heterogeneity of astrocytes using contemporary tools and by calling into question the assumption by classical neuroscience that neurons and glia are derived from distinct pools of progenitor cells. Astrocytes have long been neglected as active participants in intercellular communication and information processing in the central nervous system, in part due to their lack of electrical excitability. The follow up chapters review the “nuts and bolts” of ast- cytic physiology; astrocytes possess a diverse assortment of ion channels, neu- transmitter receptors, and transport mechanisms that enable the astrocytes to respond to many of the same signals that act on neurons. Since astrocytes can detect chemical transmitters that are released from neurons and can release their own extracellular signals there is an increasing awareness that they play physiological roles in regulating neuronal activity and synaptic transmission. In addition to these physiological roles, it is becoming increasingly recognized that astrocytes play critical roles during pathophysiological states of the nervous system; these states include gliomas, Alexander disease, and epilepsy to mention a few.

Focus on Neurochemistry Research

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Publisher : Nova Publishers
ISBN 13 : 9781594544170
Total Pages : 270 pages
Book Rating : 4.5/5 (441 download)

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Book Synopsis Focus on Neurochemistry Research by : Robert M. Coleman

Download or read book Focus on Neurochemistry Research written by Robert M. Coleman and published by Nova Publishers. This book was released on 2005 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain is an enormously dynamic organ. Even when we sleep connections are made, signals sent and messages delivered. One of the key ways that the brain operates is via chemical stimuli which permits different parts of the brain to communicate between themselves and with the rest of the body. Determining what these chemicals, proteins and molecules are is an important way to not only discover how the brain works, but provide novel targets that may be useful in the treatment of disease, for instance in dealing with memory loss in dementia. This new book brings together international research in a broad range of topics, including molecular and cellular neurochemistry, neuropharmacology and genetic aspects of CNS function, neuroimmunology, metabolism, as well as the neurochemistry of neurological and psychiatric disorders of the CNS.

Intracranial and Intralabyrinthine Fluids

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Publisher : Springer Science & Business Media
ISBN 13 : 3642801633
Total Pages : 435 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Intracranial and Intralabyrinthine Fluids by : Arne Ernst

Download or read book Intracranial and Intralabyrinthine Fluids written by Arne Ernst and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is no question that the topic of this meeting in Seeheim, Germany, on intracranial and intralabyrinthine fluids is pertinent. This was the first international meeting at which these two closely-related topics were addressed together. Combining the clinical and research aspects of fluid and pressure regulation in the intracranial and the intralabyrint hine compartments as well as discussions on the clinical implications of abnormal fluid pressure was an excellent idea. The presentations and discussions of both the clinicians and basic scientists who participated proved that the concept of having such a combined focused gathering was both original and relevant. The two topics of the meeting in Seeheim have much in common. Maintaining both the intracranial pressure (lCP) and the intralabyrinthine pressure within normal limits is important for the normal functions of both the central nervous system and the ear. The intracranial space and the intralabyrinthine space are closed compartments that communicate with each other in an intricate manner. Deviations from normal intracranial pressure result in specific symptoms and signs. Medical problems related to elevated intracranial pressure vary from subtle to severe. Accumulated knowledge indicates that there are adverse effects from even relatively small elevations in ICP. Elevations in ICP may cause injuries to the brain and the ear. Abnormal pressure in the ear may cause abnormal function and injury. Maintaining the intracranial pressure within normal limits depends on a normally functioning pressure regulation.

Neuroglia in the Aging Brain

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Publisher : Springer Science & Business Media
ISBN 13 : 1592591051
Total Pages : 513 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Neuroglia in the Aging Brain by : Jean de Vellis

Download or read book Neuroglia in the Aging Brain written by Jean de Vellis and published by Springer Science & Business Media. This book was released on 2001-11-06 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: A distinguished panel of internationally recognized neuroscientists comprehensively review the involvement of and changes in glial cells both during the normal aging process and in the major disorders of old age. Topics range from the cellular and molecular changes that occur with aging-especially aging-associated activation of astrocytes and microglia and its relation to neuronal injury and repair-to neuron-glia intercommunication. The contributors show how glial signals may be modulated by hormones, growth factors, neurotransmitters, intracellular metabolism, and intercellular exchanges, as well as by aging of the blood-brain barrier.

Modern Techniques in Neuroscience Research

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Publisher : Springer Science & Business Media
ISBN 13 : 3642585523
Total Pages : 1336 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Modern Techniques in Neuroscience Research by : Uwe Windhorst

Download or read book Modern Techniques in Neuroscience Research written by Uwe Windhorst and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 1336 pages. Available in PDF, EPUB and Kindle. Book excerpt: An overview of the techniques used in modern neuroscience research with the emphasis on showing how different techniques can optimally be combined in the study of problems that arise at some levels of nervous system organization. This is essentially a working tool for the scientist in the laboratory and clinic, providing detailed step-by-step protocols with tips and recommendations. Most chapters and protocols are organized such that they can be used independently, while cross-references between the chapters, a glossary, a list of suppliers and appendices provide further help.

Epilepsy as a Dynamic Disease

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Publisher : Springer Science & Business Media
ISBN 13 : 366205048X
Total Pages : 439 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Epilepsy as a Dynamic Disease by : John Milton

Download or read book Epilepsy as a Dynamic Disease written by John Milton and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 439 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first book to bring together experts in epilepsy, bio-engineering and dynamical systems theory, to discuss the possibility of treating epilepsy by controlling mechanisms that cause seizures. It includes a unique reference database with more than 1000 references, including hard-to-access references in the Russian literature.

Physiological Research

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Publisher :
ISBN 13 :
Total Pages : 694 pages
Book Rating : 4.:/5 (43 download)

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Book Synopsis Physiological Research by :

Download or read book Physiological Research written by and published by . This book was released on 1991 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Canadian Journal of Physiology and Pharmacology

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Publisher :
ISBN 13 :
Total Pages : 896 pages
Book Rating : 4.3/5 (243 download)

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Book Synopsis Canadian Journal of Physiology and Pharmacology by :

Download or read book Canadian Journal of Physiology and Pharmacology written by and published by . This book was released on 1996 with total page 896 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Calcium Signalling in the Nervous System

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Publisher :
ISBN 13 :
Total Pages : 234 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Calcium Signalling in the Nervous System by : P. G. Kostyuk

Download or read book Calcium Signalling in the Nervous System written by P. G. Kostyuk and published by . This book was released on 1995 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: Calcium ions play an important role in the function of excitable cells, from the triggering of impulses in nerve cells to the regulation of biochemical pathways and basic cellular functions of all cell types in the nervous system. Calcium signalling is the main coupling mechanism linking external stimuli, via the membrane, with intracellular processes. Calcium Signalling in the Nervous System provides an up-to-date account of the most fundamental aspects of calcium signal generation in the nervous system, including pathways for Ca2+ influx, buffering in the cytosol, involvement of intracellular calcium stores and Ca2+ extrusion. The book also gives an overview of the most important aspects of interaction of Ca2+ ions with other messenger systems, the functional meaning of Ca2+ ions, as well as the pharmaceutical tools used for their dissection and modulation. The role of calcium in a variety of neural cell types and implications in brain function are also discussed, including the control of gene expression, cell differentiation and programmed cell death.

Verhandlungen der Deutschen Zoologischen Gesellschaft

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Publisher :
ISBN 13 :
Total Pages : 242 pages
Book Rating : 4.:/5 (46 download)

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Book Synopsis Verhandlungen der Deutschen Zoologischen Gesellschaft by : Deutsche Zoologische Gesellschaft

Download or read book Verhandlungen der Deutschen Zoologischen Gesellschaft written by Deutsche Zoologische Gesellschaft and published by . This book was released on 1994 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: List of members in each vol.

Encyclopedia of Neuroscience

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Publisher : Elsevier Science & Technology
ISBN 13 :
Total Pages : 1156 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Encyclopedia of Neuroscience by : George Adelman

Download or read book Encyclopedia of Neuroscience written by George Adelman and published by Elsevier Science & Technology. This book was released on 1999 with total page 1156 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hardbound. The first edition of the Encyclopedia of Neuroscience has, since its publication nearly ten years ago, become the standard reference work designed to make the neurosciences readily accessible to both the specialist and non-specialist reader.This landmark work, with its broad scope and interdisciplinary coverage, has become an essential reference and learning tool for everyone involved in the study of the brain and how it mediates behavior.Now, the Encyclopedia has been expanded and updated, in most cases by the original authors, and is available both on CD-ROM and in print. The Encyclopedia represents the culmination of a massive international effort to present the neurosciences in one concise source. Edited by George Adelman and Barry Smith, and compiled under the guidance of an outstanding and distinguished Scientific Advisory Board, it includes contributions from renowned experts in their respective fields from around the