Investigations on Signal Transduction Processes Utilizing Small Chemical Probes

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Publisher : Springer Nature
ISBN 13 : 9811995850
Total Pages : 72 pages
Book Rating : 4.8/5 (119 download)

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Book Synopsis Investigations on Signal Transduction Processes Utilizing Small Chemical Probes by : Lihe Zhang

Download or read book Investigations on Signal Transduction Processes Utilizing Small Chemical Probes written by Lihe Zhang and published by Springer Nature. This book was released on with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mass Spectrometry-Based Chemical Proteomics

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Publisher : John Wiley & Sons
ISBN 13 : 1118970217
Total Pages : 448 pages
Book Rating : 4.1/5 (189 download)

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Book Synopsis Mass Spectrometry-Based Chemical Proteomics by : W. Andy Tao

Download or read book Mass Spectrometry-Based Chemical Proteomics written by W. Andy Tao and published by John Wiley & Sons. This book was released on 2019-07-10 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: PROVIDES STRATEGIES AND CONCEPTS FOR UNDERSTANDING CHEMICAL PROTEOMICS, AND ANALYZING PROTEIN FUNCTIONS, MODIFICATIONS, AND INTERACTIONS—EMPHASIZING MASS SPECTROMETRY THROUGHOUT Covering mass spectrometry for chemical proteomics, this book helps readers understand analytical strategies behind protein functions, their modifications and interactions, and applications in drug discovery. It provides a basic overview and presents concepts in chemical proteomics through three angles: Strategies, Technical Advances, and Applications. Chapters cover those many technical advances and applications in drug discovery, from target identification to validation and potential treatments. The first section of Mass Spectrometry-Based Chemical Proteomics starts by reviewing basic methods and recent advances in mass spectrometry for proteomics, including shotgun proteomics, quantitative proteomics, and data analyses. The next section covers a variety of techniques and strategies coupling chemical probes to MS-based proteomics to provide functional insights into the proteome. In the last section, it focuses on using chemical strategies to study protein post-translational modifications and high-order structures. Summarizes chemical proteomics, up-to-date concepts, analysis, and target validation Covers fundamentals and strategies, including the profiling of enzyme activities and protein-drug interactions Explains technical advances in the field and describes on shotgun proteomics, quantitative proteomics, and corresponding methods of software and database usage for proteomics Includes a wide variety of applications in drug discovery, from kinase inhibitors and intracellular drug targets to the chemoproteomics analysis of natural products Addresses an important tool in small molecule drug discovery, appealing to both academia and the pharmaceutical industry Mass Spectrometry-Based Chemical Proteomics is an excellent source of information for readers in both academia and industry in a variety of fields, including pharmaceutical sciences, drug discovery, molecular biology, bioinformatics, and analytical sciences.

Visualizing Chemistry

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Publisher : National Academies Press
ISBN 13 : 030916463X
Total Pages : 222 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Visualizing Chemistry by : National Research Council

Download or read book Visualizing Chemistry written by National Research Council and published by National Academies Press. This book was released on 2006-06-01 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientists and engineers have long relied on the power of imaging techniques to help see objects invisible to the naked eye, and thus, to advance scientific knowledge. These experts are constantly pushing the limits of technology in pursuit of chemical imagingâ€"the ability to visualize molecular structures and chemical composition in time and space as actual events unfoldâ€"from the smallest dimension of a biological system to the widest expanse of a distant galaxy. Chemical imaging has a variety of applications for almost every facet of our daily lives, ranging from medical diagnosis and treatment to the study and design of material properties in new products. In addition to highlighting advances in chemical imaging that could have the greatest impact on critical problems in science and technology, Visualizing Chemistry reviews the current state of chemical imaging technology, identifies promising future developments and their applications, and suggests a research and educational agenda to enable breakthrough improvements.

Systems Biomedicine Approaches in Cancer Research

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Publisher : Springer Nature
ISBN 13 : 9811919534
Total Pages : 170 pages
Book Rating : 4.8/5 (119 download)

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Book Synopsis Systems Biomedicine Approaches in Cancer Research by : Shailza Singh

Download or read book Systems Biomedicine Approaches in Cancer Research written by Shailza Singh and published by Springer Nature. This book was released on 2022-08-10 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the applications of systems biology and synthetic biology in cancer medicine. It highlights the use of computational and mathematical models to decipher the complexity of cancer heterogeneity. The book emphasizes the modeling approaches for predicting behavior of cancer cells, tissues in context of drug response, and angiogenesis. It introduces cell-based therapies for the treatment of various cancers and reviews the role of neural networks for drug response prediction. Further, it examines the system biology approaches for the identification of medicinal plants in cancer drug discovery. It explores the opportunities for metabolic engineering in the realm of cancer research towards development of new cancer therapies based on metabolically derived targets. Lastly, it discusses the applications of data mining techniques in cancer research. This book is an excellent guide for oncologists and researchers who are involved in the latest cancer research.

Medicinal Chemistry

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Publisher :
ISBN 13 :
Total Pages : 488 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Medicinal Chemistry by : Frank D. King

Download or read book Medicinal Chemistry written by Frank D. King and published by . This book was released on 2002 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is an valuable introduction to medicinal chemistry for new graduates and PhDs. It will also serve to update more experienced scientists on the newer technologies in the field.

Office of Naval Research Guide to Programs

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Publisher :
ISBN 13 :
Total Pages : 88 pages
Book Rating : 4.:/5 (3 download)

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Book Synopsis Office of Naval Research Guide to Programs by : United States. Office of Naval Research

Download or read book Office of Naval Research Guide to Programs written by United States. Office of Naval Research and published by . This book was released on 1992 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Office of Naval Research Guide to Programs

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Publisher :
ISBN 13 :
Total Pages : 88 pages
Book Rating : 4.3/5 ( download)

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Book Synopsis Office of Naval Research Guide to Programs by : United States. Office of the Chief of Naval Research

Download or read book Office of Naval Research Guide to Programs written by United States. Office of the Chief of Naval Research and published by . This book was released on 1992 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt:

DNA Nanotechnology for Cell Research

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Publisher : John Wiley & Sons
ISBN 13 : 3527351736
Total Pages : 549 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis DNA Nanotechnology for Cell Research by : Zhou Nie

Download or read book DNA Nanotechnology for Cell Research written by Zhou Nie and published by John Wiley & Sons. This book was released on 2024-02-20 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA Nanotechnology for Cell Research Comprehensive coverage of DNA nanotechnology with a focus on its biomedical applications in disease diagnosis, gene therapy, and drug delivery Bringing together multidisciplinary aspects of chemical, material, and biological engineering, DNA Nanotechnology for Cell Research: From Bioanalysis to Biomedicine presents an overview of DNA nanotechnology with emphasis on a variety of different applications in cell research and engineering, covering a unique collection of DNA nanotechnology for fundamental research and engineering of living cells, mostly in cellulo and in vivo, for the first time. Broad coverage of this book ranges from pioneering concepts of DNA nanotechnology to cutting-edge reports regarding the use of DNA nanotechnology for fundamental cell science and related biomedical engineering applications in sensing, bioimaging, cell manipulation, gene therapy, and drug delivery. The text is divided into four parts. Part I surveys the progress of functional DNA nanotechnology tools for cellular recognition. Part II illustrates the use of DNA-based biochemical sensors to monitor and image intracellular molecules and processes. Part III examines the use of DNA to regulate biological functions of individual cells. Part IV elucidates the use of DNA nanotechnology for cell-targeted medical applications. Sample topics covered in DNA Nanotechnology for Cell Research include: Selections and applications of functional nucleic acid toolkits, including DNA/RNA aptamers, DNAzymes, and riboswitches, for cellular recognition, metabolite detection, and liquid biopsy. Developing intelligent DNA nanodevices implemented in living cells for amplified cell imaging, smart intracellular sensing, and in cellulo programmable biocomputing. Harnessing dynamic DNA nanotechnology for non-genetic cell membrane engineering, receptor signaling reprogramming, and cellular behavior regulation. Construction of biocompatible nucleic acid nanostructures as precisely controlled vehicles for drug delivery, immunotherapy, and tissue engineering. Providing an up-to-date tutorial style overview along with a highly valuable in-depth perspective, DNA Nanotechnology for Cell Research is an essential resource for the entire DNA-based nanotechnology community, including analytical chemists, biochemists, materials scientists, and bioengineers.

Beyond the Molecular Frontier

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Publisher : National Academies Press
ISBN 13 : 0309168392
Total Pages : 238 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Beyond the Molecular Frontier by : National Research Council

Download or read book Beyond the Molecular Frontier written by National Research Council and published by National Academies Press. This book was released on 2003-03-19 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemistry and chemical engineering have changed significantly in the last decade. They have broadened their scopeâ€"into biology, nanotechnology, materials science, computation, and advanced methods of process systems engineering and controlâ€"so much that the programs in most chemistry and chemical engineering departments now barely resemble the classical notion of chemistry. Beyond the Molecular Frontier brings together research, discovery, and invention across the entire spectrum of the chemical sciencesâ€"from fundamental, molecular-level chemistry to large-scale chemical processing technology. This reflects the way the field has evolved, the synergy at universities between research and education in chemistry and chemical engineering, and the way chemists and chemical engineers work together in industry. The astonishing developments in science and engineering during the 20th century have made it possible to dream of new goals that might previously have been considered unthinkable. This book identifies the key opportunities and challenges for the chemical sciences, from basic research to societal needs and from terrorism defense to environmental protection, and it looks at the ways in which chemists and chemical engineers can work together to contribute to an improved future.

Catalog of Federal Domestic Assistance

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Catalog of Federal Domestic Assistance by :

Download or read book Catalog of Federal Domestic Assistance written by and published by . This book was released on 1991 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Identifies and describes specific government assistance opportunities such as loans, grants, counseling, and procurement contracts available under many agencies and programs.

Update to the ... Catalog of Federal Domestic Assistance

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Publisher :
ISBN 13 :
Total Pages : 574 pages
Book Rating : 4.:/5 (3 download)

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Book Synopsis Update to the ... Catalog of Federal Domestic Assistance by :

Download or read book Update to the ... Catalog of Federal Domestic Assistance written by and published by . This book was released on 1991 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt:

ERDA Energy Research Abstracts

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Publisher :
ISBN 13 :
Total Pages : 1314 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis ERDA Energy Research Abstracts by : United States. Energy Research and Development Administration

Download or read book ERDA Energy Research Abstracts written by United States. Energy Research and Development Administration and published by . This book was released on 1976 with total page 1314 pages. Available in PDF, EPUB and Kindle. Book excerpt:

ERDA Energy Research Abstracts

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Publisher :
ISBN 13 :
Total Pages : 1118 pages
Book Rating : 4.3/5 (129 download)

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Book Synopsis ERDA Energy Research Abstracts by : United States. Energy Research and Development Administration. Technical Information Center

Download or read book ERDA Energy Research Abstracts written by United States. Energy Research and Development Administration. Technical Information Center and published by . This book was released on 1976 with total page 1118 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Textbook of Pharmaceutical Medicine

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Publisher : John Wiley & Sons
ISBN 13 : 9781444317565
Total Pages : 776 pages
Book Rating : 4.3/5 (175 download)

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Book Synopsis The Textbook of Pharmaceutical Medicine by : John P. Griffin

Download or read book The Textbook of Pharmaceutical Medicine written by John P. Griffin and published by John Wiley & Sons. This book was released on 2009-10-15 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Textbook of Pharmaceutical Medicine is a standardreference for all those working in pharmaceutical medicine and therecognised text for the UK Faculty of Pharmaceutical MedicineDiploma. This is a comprehensive volume covering the processes bywhich medicines are developed, tested and approved. Regulations fordrug development in the UK, EU, USA, Australia and Japan arediscussed, providing relevant information for drug approval in themain continents where new drugs are developed. The chapters are written by leading academics, medical directorsand lawyers, providing authoritative and in-depth information fortrainees on the Faculty course, and for physicians working in thepharmaceutical industry. As well as thorough updating of theregulatory chapters, the 6th edition includes chapters onthese vital new areas: Paediatric regulation Ethics Due diligence and the pharmaceutical physician

Chemical Biology

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Publisher : John Wiley & Sons
ISBN 13 : 0470090669
Total Pages : 272 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Chemical Biology by : Banafshe Larijani

Download or read book Chemical Biology written by Banafshe Larijani and published by John Wiley & Sons. This book was released on 2006-08-04 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by a team of international researchers and teachers at the cutting edge of chemical biology research, this book provides an exciting, comprehensive introduction to a wide range of chemical and physical techniques with applications in areas as diverse as molecular biology, signal transduction, drug discovery and medicine. Techniques include: Cryo-electron microscopy, atomic force microscopy, differential scanning calorimetry in the study of lipid structures, membrane potentials and membrane probes, identification and quantification of lipids using mass spectroscopy, liquid state NMR, solid state NMR in biomembranes, molecular dynamics, two dimensional infra-red studies of biomolecules, single and two-photon fluorescence, optical tweezers, PET imaging and chemical genetics. KEY FEATURES: a unique guide to the rapidly evolving, interdisciplinary field of chemical biology. adopts a molecular structure for maximum flexibility. addresses relevant, topical chemical biological questions throughout. includes stunning illustrations. associates website with PowerPoint slides of figures within the book. Chemical Biology: Techniques and Applications provides an invaluable resource for final year undergraduate and post graduate bioscience and biomedical students and pharmaceutical researchers with an interest in this fascinating, and ever changing field.

A Framework for K-12 Science Education

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Publisher : National Academies Press
ISBN 13 : 0309214459
Total Pages : 400 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis A Framework for K-12 Science Education by : National Research Council

Download or read book A Framework for K-12 Science Education written by National Research Council and published by National Academies Press. This book was released on 2012-02-28 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Science, engineering, and technology permeate nearly every facet of modern life and hold the key to solving many of humanity's most pressing current and future challenges. The United States' position in the global economy is declining, in part because U.S. workers lack fundamental knowledge in these fields. To address the critical issues of U.S. competitiveness and to better prepare the workforce, A Framework for K-12 Science Education proposes a new approach to K-12 science education that will capture students' interest and provide them with the necessary foundational knowledge in the field. A Framework for K-12 Science Education outlines a broad set of expectations for students in science and engineering in grades K-12. These expectations will inform the development of new standards for K-12 science education and, subsequently, revisions to curriculum, instruction, assessment, and professional development for educators. This book identifies three dimensions that convey the core ideas and practices around which science and engineering education in these grades should be built. These three dimensions are: crosscutting concepts that unify the study of science through their common application across science and engineering; scientific and engineering practices; and disciplinary core ideas in the physical sciences, life sciences, and earth and space sciences and for engineering, technology, and the applications of science. The overarching goal is for all high school graduates to have sufficient knowledge of science and engineering to engage in public discussions on science-related issues, be careful consumers of scientific and technical information, and enter the careers of their choice. A Framework for K-12 Science Education is the first step in a process that can inform state-level decisions and achieve a research-grounded basis for improving science instruction and learning across the country. The book will guide standards developers, teachers, curriculum designers, assessment developers, state and district science administrators, and educators who teach science in informal environments.

Inspired by Biology

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Publisher : National Academies Press
ISBN 13 : 0309134293
Total Pages : 170 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Inspired by Biology by : National Research Council

Download or read book Inspired by Biology written by National Research Council and published by National Academies Press. This book was released on 2008-06-17 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientists have long desired to create synthetic systems that function with the precision and efficiency of biological systems. Using new techniques, researchers are now uncovering principles that could allow the creation of synthetic materials that can perform tasks as precise as biological systems. To assess the current work and future promise of the biology-materials science intersection, the Department of Energy and the National Science Foundation asked the NRC to identify the most compelling questions and opportunities at this interface, suggest strategies to address them, and consider connections with national priorities such as healthcare and economic growth. This book presents a discussion of principles governing biomaterial design, a description of advanced materials for selected functions such as energy and national security, an assessment of biomolecular materials research tools, and an examination of infrastructure and resources for bridging biological and materials science.