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Introduction To Membrane Noise
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Book Synopsis Introduction to Membrane Noise by : Louis J. DeFelice
Download or read book Introduction to Membrane Noise written by Louis J. DeFelice and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 511 pages. Available in PDF, EPUB and Kindle. Book excerpt: I started working on membrane noise in 1967 with David Firth in the Department of Physiology at McGill University. I began writing this book in the summer of 1975 at Emory University under a grant from the National Library of Medicine. Part of the writing was also done at the Marine Biological Laboratory Library in Woods Hole and in the Library of the Stazione Zoologica in Naples. I wrote this book because in the intervening years membrane noise became a definable subdivision of membrane biophysics and seemed to deserve a uniform treatment in one volume. Not surprisingly, this turned out to be much more difficult than I had imagined and some areas of the subject that ought to be included have been left out, either for reasons of space or because of my own inability to keep up with all aspects of the field. This book is written for biologists interested in noise and for physicists and electrical engineers interested in biology. The first three chapters attempt to bring both groups to a common point of understanding of electronics and electrophysiology necessary to the study of noise and impedance in membranes. These chapters arose out of a course given over a period of six years to electrical engineers from the Georgia Institute of Technology and biologists from Emory University School of Medicine.
Book Synopsis Squid as Experimental Animals by : W.J., Jr. Adelman
Download or read book Squid as Experimental Animals written by W.J., Jr. Adelman and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 531 pages. Available in PDF, EPUB and Kindle. Book excerpt: The predecessor to this book was A Guide to the Laboratory Use of the Squid Loligo pealei published by the Marine Biological Laboratory, Woods Hole, Massachusetts in 1974. The revision of this long out of date guide, with the approval of the Marine Biological Laboratory, is an attempt to introduce students and researchers to the cephalopods and particularly the squid as an object of biological research. Therefore, we have decided to expand on its original theme, which was to present important practical aspects for using the squid as experimental animals. There are twenty two chapters instead of the original eight. The material in the original eight chapters has been completely revised. Since more than one method can be used for accomplishing a given task, some duplication of methods was considered desirable in the various chapters. Thus, the methodology can be chosen which is best suited for each reader's requirements. Each subject also contains a mini-review which can serve as an introduction to the various topics. Thus, the volume is not just a laboratory manual, but can also be used as an introduction to squid biology. The book is intended for laboratory technicians, advanced undergraduate students, graduate students, researchers, and all others who want to learn the purpose, methods, and techniques of using squid as experimental animals. This is the reason why the name has been changed to its present title. Preceding the chapters is a list of many of the abbreviations, prefixes, and suffixes used in this volume.
Book Synopsis Thermodynamics of Membrane Receptors and Channels by : Meyer B. Jackson
Download or read book Thermodynamics of Membrane Receptors and Channels written by Meyer B. Jackson and published by CRC Press. This book was released on 1992-11-18 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thermodynamics of Membrane Receptors and Channels synthesizes a wealth of new information regarding the biophysics of membrane proteins. New insights provided by molecular genetics, single channel recording, and high resolution structural techniques are discussed from a conceptual perspective. Basic theoretical topics are introduced, developed, and then extensively illustrated with recent results from the literature or data from the authors' own laboratories. Theoretical and experimental information is incorporated into in-depth discussions of ion permeation mechanisms, ion channel and receptor conformational changes, aggregate activity of complexes of lipids and proteins, and how coupling is achieved between different energy modes in the many transduction systems residing in biomembranes. Thermodynamics of Membrane Receptors and Channels will be valuable both as a learning aid and a reference for biophysicists, neuroscientists, cell biologists, physiologists, and other researchers investigating any aspects of biomembranes.
Book Synopsis Single-Channel Recording by : Bert Sakmann
Download or read book Single-Channel Recording written by Bert Sakmann and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Single-channel recording has become a widely used tool for the study of ion permeation mechanisms in biological membranes. Whereas the technique might have been considered an "art" after its introduction in 1976, it developed into a relatively simple method after it became possible to obtain high-resistance (several gigaohm) membrane-pipette seals. In the summer of 1982, a course on the technique was held at the Ettore Majorana Center for Scientific Culture in Erice, Sicily. It brought together people from most of the laboratories involved in patch clamping at that time. During the course, it became apparent that the technique had reached a state of maturity. Repeatedly, the opinion was expressed that a detailed description of all the aspects of the technique including representative examples of results should be available. We therefore asked the course instructors, as well as several other colleagues, to provide chapters on selected topics in order to produce this volume. The different variants of patch clamping were described quite extensively in an article by Hamill, Marty, Neher, Sakmann, and Sigworth (Pflugers Archiv 391:85) in 1981. Rather than repeating this survey in an introductory chapter, we chose to reprint that article in the Appendix of this volume (by permission of Springer-Verlag). The methods section will, therefore, go straight into detailed aspects of the technol ogy.
Book Synopsis Stochastic Transport Processes in Discrete Biological Systems by : Eckart Frehland
Download or read book Stochastic Transport Processes in Discrete Biological Systems written by Eckart Frehland and published by Springer Science & Business Media. This book was released on 2013-03-13 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: These notes are in part based on a course for advanced students in the applications of stochastic processes held in 1978 at the University of Konstanz. These notes contain the results of re cent studies on the stochastic description of ion transport through biological membranes. In particular, they serve as an introduction to an unified theory of fluctuations in complex biological transport systems. We emphasize that the subject of this volume is not to introduce the mathematics of stochastic processes but to present a field of theoretical biophysics in which stochastic methods are important. In the last years the study of membrane noise has become an important method in biophysics. Valuable information on the ion transport mechanisms in membranes can be obtained from noise analysis. A number of different processes such as the opening and closing of ion channels have been shown to be sources of the measured current or voltage fluctuations. Bio logical 'transport systems can be complex. For example, the transport process can be coupled to other processes such as chemical reactions and take place in discontinuous structures of molecular dimensions. Furthermore, since there are strong electric fields or high concentration gradients across biological membranes ion transport processes of biological relevance are mostly processes far from equilibrium. For these reasons the development of new theoretical concepts has been necessary. The concept of transport in discrete systems has turned out to be more appropriate than continuum models.
Book Synopsis Self-Organized Biological Dynamics and Nonlinear Control by : Jan Walleczek
Download or read book Self-Organized Biological Dynamics and Nonlinear Control written by Jan Walleczek and published by Cambridge University Press. This book was released on 2006-04-20 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: The growing impact of nonlinear science on biology and medicine is fundamentally changing our view of living organisms and disease processes. This book introduces the application to biomedicine of a broad range of interdisciplinary concepts from nonlinear dynamics, such as self-organization, complexity, coherence, stochastic resonance, fractals and chaos. It comprises 18 chapters written by leading figures in the field and covers experimental and theoretical research, as well as the emerging technological possibilities such as nonlinear control techniques for treating pathological biodynamics, including heart arrhythmias and epilepsy. This book will attract the interest of professionals and students from a wide range of disciplines, including physicists, chemists, biologists, sensory physiologists and medical researchers such as cardiologists, neurologists and biomedical engineers.
Book Synopsis Mathematics for Neuroscientists by : Fabrizio Gabbiani
Download or read book Mathematics for Neuroscientists written by Fabrizio Gabbiani and published by Academic Press. This book was released on 2010-09-16 with total page 505 pages. Available in PDF, EPUB and Kindle. Book excerpt: Virtually all scientific problems in neuroscience require mathematical analysis, and all neuroscientists are increasingly required to have a significant understanding of mathematical methods. There is currently no comprehensive, integrated introductory book on the use of mathematics in neuroscience; existing books either concentrate solely on theoretical modeling or discuss mathematical concepts for the treatment of very specific problems. This book fills this need by systematically introducing mathematical and computational tools in precisely the contexts that first established their importance for neuroscience. All mathematical concepts will be introduced from the simple to complex using the most widely used computing environment, Matlab. This book will provide a grounded introduction to the fundamental concepts of mathematics, neuroscience and their combined use, thus providing the reader with a springboard to cutting-edge research topics and fostering a tighter integration of mathematics and neuroscience for future generations of students. A very didactic and systematic introduction to mathematical concepts of importance for the analysis of data and the formulation of concepts based on experimental data in neuroscience Provides introductions to linear algebra, ordinary and partial differential equations, Fourier transforms, probabilities and stochastic processes Introduces numerical methods used to implement algorithms related to each mathematical concept Illustrates numerical methods by applying them to specific topics in neuroscience, including Hodgkin-Huxley equations, probabilities to describe stochastic release, stochastic processes to describe noise in neurons, Fourier transforms to describe the receptive fields of visual neurons Allows the mathematical novice to analyze their results in more sophisticated ways, and consider them in a broader theoretical framework
Book Synopsis Voltage-Sensitive Ion Channels by : H. Richard Leuchtag
Download or read book Voltage-Sensitive Ion Channels written by H. Richard Leuchtag and published by Springer Science & Business Media. This book was released on 2008-12-21 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: Voltage-sensitive ion channels are macromolecules embedded in the membranes of nerve and muscle fibers of animals. Despite decades of intensive research under the traditional approach of gated structural pores, the relation between the structure of these molecules and their function remains enigmatic. This book examines physically oriented approaches not covered in other ion-channel books, and it develops a new physics-based approach to the problem of molecular excitability.
Book Synopsis Bioengineering and Biophysical Aspects of Electromagnetic Fields, Fourth Edition by : Ben Greenebaum
Download or read book Bioengineering and Biophysical Aspects of Electromagnetic Fields, Fourth Edition written by Ben Greenebaum and published by CRC Press. This book was released on 2018-11-02 with total page 755 pages. Available in PDF, EPUB and Kindle. Book excerpt: The two volumes of this new edition of the Handbook cover the basic biological, medical, physical, and electrical engineering principles. They also include experimental results concerning how electric and magnetic fields affect biological systems—both as potential hazards to health and potential tools for medical treatment and scientific research. They also include material on the relationship between the science and the regulatory processes concerning human exposure to the fields. Like its predecessors, this edition is intended to be useful as a reference book but also for introducing the reader to bioelectromagnetics or some of its aspects. FEATURES • New topics include coverage of electromagnetic effects in the terahertz region, effects on plants, and explicitly applying feedback concepts to the analysis of biological electromagnetic effects • Expanded coverage of electromagnetic brain stimulation, characterization and modeling of epithelial wounds, and recent lab experiments on at all frequencies • Section on background for setting standards and precautionary principle • Discussion of recent epidemiological, laboratory, and theoretical results; including: WHO IARC syntheses of epidemiological results on both high and low frequency fields, IITRI lab study of cancer in mice exposed to cell phone-like radiation, and other RF studies • All chapters updated by internationally acknowledged experts in the field
Book Synopsis Membranes, Channels, and Noise by : Robert S. Eisenberg
Download or read book Membranes, Channels, and Noise written by Robert S. Eisenberg and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is a collection of papers designed to increase awareness and utilization of fluctuation theory for the description of ionic events at the membrane. The papers are revised and updated versions of presentations made at a workshop entitled "Noise Measurements as a Probe of Ionic Conductance. " As a result of discussions held at that meeting, the participants were asked to provide selected chapters designed to provide detailed descriptions of the theory and its application to a number of membrane channels. Fluctuation theory was developed initially to explain statistical fluctuations of ordinary physical quantities such as random collisions between gas molecules and walls. As knowledge of ionic pores has advanced, it has become apparent that randomized fluctuations could be utilized to characterize pore behavior in excitable and epithelial membranes. Because of the increased awareness of the applicability of fluctuation theory, the workshop participants were invited to contribute papers to this volume to provide them with an opportunity to teach others the essentials of noise measurements. The emphasis of this volume is on the practical steps which must be followed to make and interpret measurements of noise, both noise produced by natural fluctuatjons of the transport system, and noise which is the response to an applied stochastic signal. This collection of papers is meant to emphasize practical limitations as well as practical and theoretical advantages of such measurements.
Book Synopsis Electrical Properties of Cells by : Louis J. DeFelice
Download or read book Electrical Properties of Cells written by Louis J. DeFelice and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: DeFelice presents this intricate subject in an easy-to-follow, stepwise fashion: he reviews the fundamentals of electricity; transfers those principles to a biological context; and expands the discussion to encompass the subject's practical dimensions. Clear definitions and intuitive descriptions characterize the presentation, which is complemented by over 150 drawings and graphs. Mathematics is kept to the minimum necessary. The text covers both excitable and non-excitable membranes and includes the plasma membrane as well as intracellular membranes. A unique, `electronics-made-simple' appendix, designed specifically for biologists, treats the operational amplifiers used in patch clamp, and other appendices offer solutions to equations and examples that illustrate principles.
Book Synopsis Modeling in the Neurosciences by : R.R. Poznanski
Download or read book Modeling in the Neurosciences written by R.R. Poznanski and published by Routledge. This book was released on 2019-01-22 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions from more than 40 renowned experts, Modeling in the Neurosciences: From Ionic Channels to Neural Networks is essential for those interested in neuronal modeling and quantitative neiroscience. Focusing on new mathematical and computer models, techniques and methods, this monograph represents a cohesive and comprehensive treatment
Book Synopsis Advances in Neural Information Processing Systems 12 by : Sara A. Solla
Download or read book Advances in Neural Information Processing Systems 12 written by Sara A. Solla and published by MIT Press. This book was released on 2000 with total page 1124 pages. Available in PDF, EPUB and Kindle. Book excerpt: The annual conference on Neural Information Processing Systems (NIPS) is the flagship conference on neural computation. It draws preeminent academic researchers from around the world and is widely considered to be a showcase conference for new developments in network algorithms and architectures. The broad range of interdisciplinary research areas represented includes computer science, neuroscience, statistics, physics, cognitive science, and many branches of engineering, including signal processing and control theory. Only about 30 percent of the papers submitted are accepted for presentation at NIPS, so the quality is exceptionally high. These proceedings contain all of the papers that were presented.
Book Synopsis Current Topics in Membranes and Transport by :
Download or read book Current Topics in Membranes and Transport written by and published by Academic Press. This book was released on 1984-09-05 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current Topics in Membranes and Transport
Book Synopsis Engineering Acoustics by : Michael Möser
Download or read book Engineering Acoustics written by Michael Möser and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: Suitable for both individual and group learning, Engineering Acoustics focuses on basic concepts and methods to make our environments quieter, both in buildings and in the open air. The author’s tutorial style derives from the conviction that understanding is enhanced when the necessity behind the particular teaching approach is made clear. He also combines mathematical derivations and formulas with extensive explanations and examples to deepen comprehension. Fundamental chapters on the physics and perception of sound precede those on noise reduction (elastic isolation) methods. The last chapter deals with microphones and loudspeakers. Moeser includes major discoveries by Lothar Cremer, including the optimum impedance for mufflers and the coincidence effect behind structural acoustic transmission. The appendix gives a short introduction on the use of complex amplitudes in acoustics.
Book Synopsis Bioengineering and Biophysical Aspects of Electromagnetic Fields by : Ben Greenebaum
Download or read book Bioengineering and Biophysical Aspects of Electromagnetic Fields written by Ben Greenebaum and published by CRC Press. This book was released on 2018-10-03 with total page 629 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioengineering and Biophysical Aspects of Electromagnetic Fields primarily contains discussions on the physics, engineering, and chemical aspects of electromagnetic (EM) fields at both the molecular level and larger scales, and investigates their interactions with biological systems. The first volume of the bestselling and newly updated Handbook of Biological Effects of Electromagnetic Fields, Third Edition, this book adds material describing recent theoretical developments, as well as new data on material properties and interactions with weak and strong static magnetic fields. Newly separated and expanded chapters describe the external and internal electromagnetic environments of organisms and recent developments in the use of RF fields for imaging. Bioengineering and Biophysical Aspects of Electromagnetic Fields provides an accessible overview of the current understanding on the scientific underpinnings of these interactions, as well as a partial introduction to experiments on the interactions themselves.
Book Synopsis Excitable Cells in Tissue Culture by : Phillip G. Nelson
Download or read book Excitable Cells in Tissue Culture written by Phillip G. Nelson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: The tissue culture approach to the study of membrane properties of excitable cells has progressed beyond the technical problems of culture methodology. Recent developments have fostered substantive contributions in research con cerned with the physiology, pharmacology, and biophysics of cell membranes in tissue culture. The scope of this volume is related to the application of tissue culture methodology to developmental processes and cellular mechanisms of electrical and chemical excitability. The major emphasis will be on the body of new biological information made available by the analytic possibilities inherent in the tissue culture systems. Naturally occurring preparations of excitable cells are frequently of suf ficient morphological complexity to compromise the analysis of the data obtained from them. Some of the limitations associated with dissected prepa rations have to do with the direct visualization of and access to the cell(s) in question and maintenance of steady-state conditions for prolonged periods of time. Since preparations in tissue culture can circumvent these problems, it is feasible to analyze the properties of identifiable cells, grown either singly or in prescribed geometries, as well as to follow the development of cellular inter actions. A crucial consideration in the use of cultured preparations is that they must faithfully capture the phenomenon of interest to the investigator. This and other potential limitations on the methodology are of necessary concern in the present volume.
