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Author : Jonathan B. Houze
Publisher :
ISBN 13 :
Total Pages : 248 pages
Book Rating : 4.F/5 ( download)
Download or read book Intramolecular Aldol Closures in the Pinene Path to Taxol written by Jonathan B. Houze and published by . This book was released on 1997 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Wei Meng
Publisher :
ISBN 13 :
Total Pages : 552 pages
Book Rating : 4.F/5 ( download)
Download or read book The Pinene Path to Taxol and Analogs written by Wei Meng and published by . This book was released on 1999 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : James C. Sutton (Jr.)
Publisher :
ISBN 13 :
Total Pages : 552 pages
Book Rating : 4.F/5 ( download)
Download or read book The Pinene Path to Taxol: I. Expanding the Scope of the Pinene Path to Taxanes: Strategies for Inclusion of Quaternary C8 Centers. II. Application of a Samarium Diiodide Reductive Cyclization to the Synthesis of the Taxane Tricyclic Core. III. Synthesis of a Highly Functionalized Taxane AB-bicycle: a Key Intermediate in the Total Synthesis of Taxol written by James C. Sutton (Jr.) and published by . This book was released on 1996 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 856 pages
Book Rating : 4.F/5 ( download)
Download or read book Dissertation Abstracts International written by and published by . This book was released on 1999 with total page 856 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Stanford University
Publisher :
ISBN 13 :
Total Pages : 506 pages
Book Rating : 4.F/5 ( download)
Download or read book Annual Commencement written by Stanford University and published by . This book was released on 1996 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Jie Jack Li
Publisher : Springer Science & Business Media
ISBN 13 : 3642340652
Total Pages : 292 pages
Book Rating : 4.6/5 (423 download)
Download or read book Total Synthesis of Natural Products written by Jie Jack Li and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'Total Synthesis of Natural Products' is written and edited by some of today's leaders in organic chemistry. Eleven chapters cover a range of natural products, from steroids to alkaloids. Each chapter contains an introduction to the natural product in question, descriptions of its biological and pharmacological properties and outlines of total synthesis procedures already carried out. Particular emphasis is placed on novel methodologies developed by the respective authors and their research groups. This text is ideal for graduate and advanced undergraduate students, as well as organic chemists in academia and industry.
Author : Hideji Itokawa
Publisher : CRC Press
ISBN 13 : 1134427662
Total Pages : 443 pages
Book Rating : 4.1/5 (344 download)
Download or read book Taxus written by Hideji Itokawa and published by CRC Press. This book was released on 2003-02-13 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: Taxol, originally derived from the North American Yew tree in 1971, is well-known worldwide as a powerful anticancer agent. Mechanistically, it has a unique microtubule stabilizing activity, and was clinically developed as a therapeutic agent in the treatment of breast and ovarian cancers at the National Cancer Institute, Washington D.C., USA. I
Author : Gunda I. Georg
Publisher : American Chemical Society
ISBN 13 :
Total Pages : 376 pages
Book Rating : 4.3/5 (91 download)
Download or read book Taxane Anticancer Agents written by Gunda I. Georg and published by American Chemical Society. This book was released on 1995 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents an overview of the development of paclitaxel as an anticancer drug, including the discovery, initial development, current status, supply issues, and recent clinical developments. Discusses in detail the cellular mechanism of action and the toxicity of paclitaxel. Presents drug delivery and taxotere metabolism. Explains semisynthetic and medicinal chemistry studies. Covers approaches to the total synthesis of paclitaxel.
Author : Paul M. Dewick
Publisher : John Wiley & Sons
ISBN 13 : 9780471496410
Total Pages : 524 pages
Book Rating : 4.4/5 (964 download)
Download or read book Medicinal Natural Products written by Paul M. Dewick and published by John Wiley & Sons. This book was released on 2002-01-03 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: This guide covers classes of natural products in medicine, whether derived from plants, micro-organisms or animals. Structured according to biosynthetic pathway, it is written from a chemistry-based approach.
Author : Paul Edward Floreancig
Publisher :
ISBN 13 :
Total Pages : 234 pages
Book Rating : 4.F/5 ( download)
Download or read book The Development of a Strategy for the Synthesis of Taxol and Taxol Analogs written by Paul Edward Floreancig and published by . This book was released on 1997 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Eder João Lenardão
Publisher : Springer
ISBN 13 : 3319924052
Total Pages : 194 pages
Book Rating : 4.3/5 (199 download)
Download or read book New Frontiers in Organoselenium Compounds written by Eder João Lenardão and published by Springer. This book was released on 2018-06-29 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents recent advances in and perspectives on the use of organoselenium compounds, primarily highlighting the new frontiers in the field of Green Chemistry, their therapeutic and biological relevance and new materials. Throughout its 200 pages, readers will find an updated and comprehensive review of new aspects of organoselenium chemistry and biochemistry. Fully referenced and written in an easy to read style, it offers readers a primary resource for including organoselenium derivatives in their projects. This book will be of interest to specialists, students and researchers involved in a broad range of fields, from synthetic green chemistry to medicinal chemistry and the chemistry of natural products. The connection between organoselenium compounds and green chemistry, despite having only recently emerged, is one of the subjects of this book. The first chapter highlights the use of Se-containing molecules as reagents and catalysts in new green protocols to access important organic transformations. The book provides a wealth of examples of bioactive Se-containing molecules, especially focusing on those with potential therapeutic uses. The second chapter focuses on the state of the art concerning the role of organoselenium compounds as antioxidants, GPx mimics, and derivatives endowed with different bioactive properties. “Organoselenium in nature” is the title of the third chapter, which equips readers with essential information on the main natural organoselenium compounds and where they are found. Selected aspects of the metabolism of selenium in plants and microorganisms are also discussed. In closing, the book includes a chapter dedicated to recent advances concerning the nonbonding interactions between organochalcogen compounds. This is currently a hot topic in selenium chemistry and biochemistry, and here readers will find key insights into the chalcogen bond and its role in the biological activity of organoselenium compounds.
Author : Professor Satyajit D. Sarker
Publisher : John Wiley & Sons
ISBN 13 : 1118687531
Total Pages : 397 pages
Book Rating : 4.1/5 (186 download)
Download or read book Chemistry for Pharmacy Students written by Professor Satyajit D. Sarker and published by John Wiley & Sons. This book was released on 2013-05-28 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book has succeeded in covering the basic chemistry essentials required by the pharmaceutical science student... the undergraduate reader, be they chemist, biologist or pharmacist will find this an interesting and valuable read." –Journal of Chemical Biology, May 2009 Chemistry for Pharmacy Students is a student-friendly introduction to the key areas of chemistry required by all pharmacy and pharmaceutical science students. The book provides a comprehensive overview of the various areas of general, organic and natural products chemistry (in relation to drug molecules). Clearly structured to enhance student understanding, the book is divided into six clear sections. The book opens with an overview of general aspects of chemistry and their importance to modern life, with particular emphasis on medicinal applications. The text then moves on to a discussion of the concepts of atomic structure and bonding and the fundamentals of stereochemistry and their significance to pharmacy- in relation to drug action and toxicity. Various aspects of aliphatic, aromatic and heterocyclic chemistry and their pharmaceutical importance are then covered with final chapters looking at organic reactions and their applications to drug discovery and development and natural products chemistry. accessible introduction to the key areas of chemistry required for all pharmacy degree courses student-friendly and written at a level suitable for non-chemistry students includes learning objectives at the beginning of each chapter focuses on the physical properties and actions of drug molecules
Author : Charles S Sell
Publisher : Royal Society of Chemistry
ISBN 13 : 178801832X
Total Pages : 432 pages
Book Rating : 4.7/5 (88 download)
Download or read book A Fragrant Introduction to Terpenoid Chemistry written by Charles S Sell and published by Royal Society of Chemistry. This book was released on 2019-05-16 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Terpenoids play an important part in all our lives, from Vitamin A and hormones to perfumes and pharmaceuticals. This book provides an introduction to terpenoid chemistry, concentrating on the lower terpenoids, but the basic principles taught are also the foundation for the chemistry of the higher terpenoids. Coverage includes: the biogenesis of terpenoids; some of the history of the field; the principles of structural determination; and the importance of stereochemistry and stereoselective synthesis. Carbocation chemistry is introduced, as are the principles of total and partial synthesis. Finally, industrial chemistry (both discovery chemistry and chemical process development) is discussed, using the volatile terpenoids of perfumery to illustrate basic concepts. Ideal as both an introduction to terpenoid chemistry and as a refresher course, A Fragrant Introduction to Terpenoid Chemistry, with its real-life problems and appreciation of the relevance of chemistry to everyday life, will prove invaluable to students, lecturers and industrialists alike.
Author : Valdir Cechinel Filho
Publisher : Springer
ISBN 13 : 3030005453
Total Pages : 531 pages
Book Rating : 4.0/5 (3 download)
Download or read book Natural Products as Source of Molecules with Therapeutic Potential written by Valdir Cechinel Filho and published by Springer. This book was released on 2018-12-07 with total page 531 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses the highly relevant and complex subject of research on drugs from natural products, discussing the current hot topics in the field. It also provides a detailed overview of the strategies used to research and develop these drugs. Respected experts explore issues involved in the production chain and when looking for new medicinal agents, including aspects such as therapeutic potential, functional foods, ethnopharmacology, metabolomics, virtual screening and regulatory scenarios. Further, the book describes strategic methods of isolation and characterization of active principles, biological assays, biotechnology of plants, synthesis, clinical trials and the use of tools to identity active principles.
Author : Anne E. Osbourn
Publisher : Springer Science & Business Media
ISBN 13 : 0387854983
Total Pages : 588 pages
Book Rating : 4.3/5 (878 download)
Download or read book Plant-derived Natural Products written by Anne E. Osbourn and published by Springer Science & Business Media. This book was released on 2009-07-07 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plants produce a huge array of natural products (secondary metabolites). These compounds have important ecological functions, providing protection against attack by herbivores and microbes and serving as attractants for pollinators and seed-dispersing agents. They may also contribute to competition and invasiveness by suppressing the growth of neighboring plant species (a phenomenon known as allelopathy). Humans exploit natural products as sources of drugs, flavoring agents, fragrances and for a wide range of other applications. Rapid progress has been made in recent years in understanding natural product synthesis, regulation and function and the evolution of metabolic diversity. It is timely to bring this information together with contemporary advances in chemistry, plant biology, ecology, agronomy and human health to provide a comprehensive guide to plant-derived natural products. Plant-derived natural products: synthesis, function and application provides an informative and accessible overview of the different facets of the field, ranging from an introduction to the different classes of natural products through developments in natural product chemistry and biology to ecological interactions and the significance of plant-derived natural products for humans. In the final section of the book a series of chapters on new trends covers metabolic engineering, genome-wide approaches, the metabolic consequences of genetic modification, developments in traditional medicines and nutraceuticals, natural products as leads for drug discovery and novel non-food crops.
Author : Guo-Qiang Lin
Publisher : John Wiley & Sons
ISBN 13 : 0471465240
Total Pages : 536 pages
Book Rating : 4.4/5 (714 download)
Download or read book Principles and Applications of Asymmetric Synthesis written by Guo-Qiang Lin and published by John Wiley & Sons. This book was released on 2003-05-29 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: Asymmetric synthesis remains a challenge to practicing scientistsas the need for enantiomerically pure or enriched compoundscontinues to increase. Over the last decade, a large amount ofliterature has been published in this field. Principles andApplications of Asymmetric Synthesis consolidates and evaluates themost useful methodologies into a one-volume resource for theconvenience of practicing scientists and students. Authored by internationally renowned scientists in the field, thisreliable reference covers more than 450 reactions and includesimportant stoichiometric as well as catalytic asymmetric reactions.The first chapter reviews the basic principles, commonnomenclature, and analytical methods, and the remainder of the bookis organized according to reaction type. The text examines suchtopics as: Carbon-carbon bond formations involving carbonyls, enamines,imines, and enolates Asymmetric C-O bond formations including epoxidation,dihydroxylation, and aminohydroxylation Asymmetric synthesis using the Diels-Alder reaction and othercyclizations Applications to the total synthesis of natural products Use of enzymes in asymmetric synthesis Practicing chemists in the pharmaceutical, fine chemical, andagricultural professions as well as graduate students will findthat Principles and Applications of Asymmetric Synthesis affordscomprehensive and current coverage.
Author : Ramesh C Gupta
Publisher : Academic Press
ISBN 13 : 0128212462
Total Pages : 1397 pages
Book Rating : 4.1/5 (282 download)
Download or read book Nutraceuticals written by Ramesh C Gupta and published by Academic Press. This book was released on 2021-01-27 with total page 1397 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nutraceuticals: Efficacy, Safety and Toxicity, Second Edition, brings together everything that is currently known about nutraceuticals and their potential toxic effects. The book introduces readers to nutraceuticals, herbal medicines, Ayurvedic medicines, prebiotics, probiotics, adaptogens, and their uses and specific applications. This essential reference discusses the mechanism of action for the judicious use of these nutraceuticals and the best tools for their evaluation before detailing the safety and toxicity of nutraceuticals and interactions with other therapeutic drugs. Finally, and crucially, regulatory aspects from around the world are covered. Completely revised and updated, this updated edition provides toxicologists, pharmacologists, pharmaceutical scientists, and those interested in medicinal plants and natural products with a comprehensive overview of the most effective tools upon which to evaluate the safety and toxicity of nutraceuticals, prebiotics, probiotics and alternative medicines. - Presents a completely revised and updated resource on the impact of nutraceuticals and various disease states such as diabetes and ophthalmic and dermal diseases - Grants an overview of the current state-of-the-science of nutraceuticals, their use and applications, and known adverse effects - Provides effective tools to evaluate the potential toxicity of any nutraceutical - Includes details of regulatory issues as written by international experts
