Intractable Seizures

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Models of Seizures and Epilepsy

Author : Asla Pitkänen
Publisher : Academic Press
ISBN 13 : 012804067X
Total Pages : 1178 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Models of Seizures and Epilepsy by : Asla Pitkänen

Download or read book Models of Seizures and Epilepsy written by Asla Pitkänen and published by Academic Press. This book was released on 2017-06-14 with total page 1178 pages. Available in PDF, EPUB and Kindle. Book excerpt: Models of Seizures and Epilepsy, Second Edition, is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models to address key questions in the field. The book also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research as well as R&D drug development. Contents include the current spectrum of models available to model different epilepsy syndromes, epilepsy in transgenic animals, comorbidities in models of epilepsy, and novel technologies to study seizures and epilepsies in animals. Provides a comprehensive reference detailing animal models of epilepsy and seizure Offers insights on the use of novel technologies that can be applied in experimental epilepsy research Edited by leading experts in the field that provide not only technical reviews of these models but also conceptual critiques Comments on the strengths and limitations of various models, including their relationship to clinical phenomenology and their value in developing better understanding and treatments

Intractable Seizures

Author : W. McIntyre Burnham
Publisher : Springer Science & Business Media
ISBN 13 : 1461513359
Total Pages : 252 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Intractable Seizures by : W. McIntyre Burnham

Download or read book Intractable Seizures written by W. McIntyre Burnham and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: About 20% of people with epilepsy have seizures which are resistant to anticonvulsant medications. These drug-resistant seizures are called `intractable', and the patients who have them - about 1 in 500 of the general population - present a major challenge to neurologists and epilepsy associations. The present volume describes the symptomatology of the major `intractable' syndromes, the most appropriate drugs for each, and the possibilities for surgical control. Research related to the causes and effects of unchecked seizures is presented, and new directions in prevention and therapy are discussed.

Intractable Focal Epilepsy

Author : John Oxbury
Publisher : Bailliere Tindall Limited
ISBN 13 : 9780702024283
Total Pages : 0 pages
Book Rating : 4.0/5 (242 download)

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Book Synopsis Intractable Focal Epilepsy by : John Oxbury

Download or read book Intractable Focal Epilepsy written by John Oxbury and published by Bailliere Tindall Limited. This book was released on 2000 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intractable Focal Epilepsyis a definitive multi author reference work covering the most difficult to treat epilepsies. The natural history, pathology and treatment, both medical and surgical, of the conditions underlying intractable seizures are fully described and illustrated. Including contributions from North America, Europe and the Pacific Rim, the emphasis throughout is on clinical diagnosis and treatment both medical and surgical, and their respective outcomes. The text is enhanced by over 250 illustrations, and the clear modern design enables the reader to assimilate information quickly. In addition to clinical treatment, there is a section on the costs of persistent intractable focal epilepsy and the costs of surgical treatment. Drs Oxbury, Polkey and Duchowny have produced a book that will appeal to epileptologists, paediatric neurologists, and neurosurgeons. The books clinical strengths will make it an invaluable working tool. Definitive resource on difficult to treat epilepsies Covers manifestation, consequences and treatment Major section on surgical treatment of focal epilepsy Complete coverage of paediatric diagnosis and treatment Special "Case Reports" give practical case histories to illustrate clinical points International line up of contributors

Magnetic Resonance in Epilepsy

Author : Ruben Kuzniecky
Publisher : Academic Press
ISBN 13 : 0080535712
Total Pages : 461 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Magnetic Resonance in Epilepsy by : Ruben Kuzniecky

Download or read book Magnetic Resonance in Epilepsy written by Ruben Kuzniecky and published by Academic Press. This book was released on 2005-01-19 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: Remarkable advances in imaging have increased the importance of MRI for diagnostic, treatment and management of epilepsy. Neuroimaging of patients with epilepsy no longer simply deals with the technology and interpretation of images but also with issues of brain metabolism, energetics, cognition and brain dysfunction. The first edition of Magnetic Resonance in Epilepsy came into clinical practice in 1995 with a revolutionary idea; that is, MR is as important as EEG in the clinical management of patients with epilepsy. The second edition of Magnetic Resonance in Epilepsy, the only comprehensive text in the field of epilepsy neuroimaging, reviews fundamental concepts and new advances in MR technology, computerized analysis, MR spectroscopy, DWI and other neuroimaging techniques such as PET, SPECT and MEG application to the study of patients with epileptic disorders. *Provides a crucial update of recent advances in imaging techniques*Timely publication as subject of neuroimaging is a very "hot" area in both clinical epilepsy and basic neuroscience research*Editors are well-respected in this field

The Epilepsies

Author : Chrysostomos P. Panayiotopoulos
Publisher : Springer
ISBN 13 :
Total Pages : 570 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Epilepsies by : Chrysostomos P. Panayiotopoulos

Download or read book The Epilepsies written by Chrysostomos P. Panayiotopoulos and published by Springer. This book was released on 2005 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives an exhaustive account of the classification and management of epileptic disorders. It provides clear didactic guidance on the diagnosis and treatment of epileptic syndromes and seizures through thirteen chapters, complemented by a pharmacopoeia and CD ROM of video-EEGs.

Epilepsy

Author : Gregory D. Cascino
Publisher : John Wiley & Sons
ISBN 13 : 1119431824
Total Pages : 550 pages
Book Rating : 4.1/5 (194 download)

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Book Synopsis Epilepsy by : Gregory D. Cascino

Download or read book Epilepsy written by Gregory D. Cascino and published by John Wiley & Sons. This book was released on 2021-08-02 with total page 550 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed to provide a comprehensive but accessible introduction to epilepsy and seizure disorders, Epilepsy, 2nd edition provides state-of-the-art information in a concise format useful to a wide audience, from neurology residents to epilepsy fellows and practitioners. This illustrated guide to the assessment, diagnosis, and treatment of epilepsy is a valuable resource enabling clinicians to stay on top of the latest recommendations for best practice.

The Comorbidities of Epilepsy

Author : Marco Mula
Publisher : Academic Press
ISBN 13 : 0128148780
Total Pages : 413 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis The Comorbidities of Epilepsy by : Marco Mula

Download or read book The Comorbidities of Epilepsy written by Marco Mula and published by Academic Press. This book was released on 2019-04-20 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epilepsy is one of most frequent neurological disorders affecting about 50 million people worldwide and 50% of them have at least another medical problem in comorbidity; sometimes this is a the cause of the epilepsy itself or it is due to shared neurobiological links between epilepsy and other medical conditions; other times it is a long-term consequence of the antiepileptic drug treatment. The Comorbidities of Epilepsy offers an up-to-date, comprehensive overview of all comorbidities of epilepsy (somatic, neurological and behavioral), by international authorities in the field of clinical epileptology, with an emphasis on epidemiology, pathophysiology, diagnosis and management. This book includes also a critical appraisal of the methodological aspects and limitations of current research on this field. Pharmacological issues in the management of comorbidities are discussed, providing information on drug dosages, side effects and interactions, in order to enable the reader to manage these patients safely. The Comorbidities of Epilepsy is aimed at all health professionals dealing with people with epilepsy including neurologists, epileptologists, psychiatrists, clinical psychologists, epilepsy specialist nurses and clinical researchers. Provides a comprehensive overview of somatic, neurological and behavioral co-morbidities of epilepsy Discusses up-to-date management of comorbidities of epilepsy Written by a group of international experts in the field

Jasper's Basic Mechanisms of the Epilepsies

Author : Jeffrey L. Noebels
Publisher : OUP USA
ISBN 13 : 0199746540
Total Pages : 1258 pages
Book Rating : 4.1/5 (997 download)

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Book Synopsis Jasper's Basic Mechanisms of the Epilepsies by : Jeffrey L. Noebels

Download or read book Jasper's Basic Mechanisms of the Epilepsies written by Jeffrey L. Noebels and published by OUP USA. This book was released on 2012-06-29 with total page 1258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.

Neurological Emergencies

Author : S.D. Shorvon
Publisher : Butterworth-Heinemann
ISBN 13 : 1483182681
Total Pages : 121 pages
Book Rating : 4.4/5 (831 download)

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Book Synopsis Neurological Emergencies by : S.D. Shorvon

Download or read book Neurological Emergencies written by S.D. Shorvon and published by Butterworth-Heinemann. This book was released on 2013-10-22 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurological Emergencies presents a comprehensive guide on the initial assessment and early treatment of patients with neurological emergencies. It discusses the diagnosis, emergency investigations, and handling of coma patients. It addresses the management of focal supratentorial lesion. Some of the topics covered in the book are the diffuse neurological or systemic disturbance; emergency resuscitation; diagnosis and treatment of transtentorial herniation; diagnosis and treatment of acute viral encephalitis; raised intracranial pressure; diagnosis and treatment of non-viral infective encephalitis; viral meningitis; meningovascular syphilis; diagnosis and treatment of cerebral abscess; diagnosis and treatment of intracranial subdural empyema; and diagnosis and treatment of cerebral venous thrombosis. The diagnosis and treatment ofstroke is fully covered. An in-depth account of the difference between haemorrhage and infarction is provided. The diagnosis of subarachnoid haemorrhage is completely presented. A chapter is devoted to the prevention of more cranial bleeding.

Pharmacoresistance in Epilepsy

Author : Luisa Rocha
Publisher : Springer Science & Business Media
ISBN 13 : 1461464641
Total Pages : 333 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Pharmacoresistance in Epilepsy by : Luisa Rocha

Download or read book Pharmacoresistance in Epilepsy written by Luisa Rocha and published by Springer Science & Business Media. This book was released on 2014-07-08 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although more than 10 new antiepileptic drugs have been developed in the past decade, epilepsy remains resistant to drug therapy in about one third of patients, many of whom struggle with the disease their entire lives. Managing these patients is a challenge and requires a structured multidisciplinary approach. The book includes chapters on all issues related to pharmacoresistance in epilepsy and describes recent developments in the pathogenesis and treatment of this disorder. It addresses abnormalities in inhibitory mechanisms, epilepsy-related changes to the immune system, development of pharmacoresistance caused by chronic exposure to antiepileptic drugs, and novel therapeutic strategies for preventing or slowing down the progression of the disease. Clinicians and basic scientists alike will find up-to-date information on the development of pharmacoesistance, as well as reviews of mechanisms associated with epilepsy that may help them consider novel strategies for preventing the development of pharmacoresistance in the first place. The book also features information on new therapeutic strategies for control of epilepsy, such as transcutaneous electrical stimulation and virtual screening of new antiepileptic drugs. Pharmacoresistance in Epilepsy: From Genes and Molecules to Promising Therapies is useful to anyone working in the field, whether they’re studying epilepsy in the lab or treating it in a doctor’s office.”

Epilepsy and Brain Tumors

Author : Herbert B. Newton
Publisher : Elsevier
ISBN 13 : 0124171265
Total Pages : 292 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis Epilepsy and Brain Tumors by : Herbert B. Newton

Download or read book Epilepsy and Brain Tumors written by Herbert B. Newton and published by Elsevier. This book was released on 2015-03-06 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Patients with brain tumor-related epilepsy (BTRE) suffer from two serious pathologies simultaneously – a brain tumor and a secondary form of epilepsy. Although there has been remarkable progress in BTRE research in recent years, it remains an on-going challenge for clinicians and continues to stimulate much debate in the scientific community. This volume is the first to be completely dedicated to BTRE, and in doing so it explores issues faced by the health care team as well as some of the novel and promising directions that future research may take. Epilepsy and Brain Tumors is not only a complete reference on BTRE but also a practical guide based on clinical experiences, with a comprehensive collection of presentations from international experts who share some of the latest discoveries and their approaches to tackling a wide range of difficult and complex issues. Includes coverage of epidemiology, pathology and treatment of both primary and metastatic brain tumors Offers additional insight into supportive care, incidence in children, focal epileptogenesis, clinical evaluation, antiepileptic drugs, surgical treatment, cognitive rehabilitation, and more Chapters authored and edited by leaders in the field around the globe – the broadest, most expert coverage available

Operative Techniques in Epilepsy Surgery

Author : Gordon H. Baltuch
Publisher : Thieme
ISBN 13 : 1626238197
Total Pages : 598 pages
Book Rating : 4.6/5 (262 download)

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Book Synopsis Operative Techniques in Epilepsy Surgery by : Gordon H. Baltuch

Download or read book Operative Techniques in Epilepsy Surgery written by Gordon H. Baltuch and published by Thieme. This book was released on 2019-11-07 with total page 598 pages. Available in PDF, EPUB and Kindle. Book excerpt: An indispensable, single-volume resource on state-of-the-art epilepsy procedures from renowned international experts! Epilepsy is a common neurological disorder affecting an estimated 1% of the population, about 20 to 30% of which experience seizures inadequately controlled by medical therapy alone. Advances in anatomic and functional imaging modalities, stereotaxy, and the integration of neuronavigation during surgery have led to cutting-edge treatment options for patients with medically refractory epilepsy. Operative Techniques in Epilepsy Surgery, Second Edition by Gordon Baltuch, Arthur Cukiert, and an impressive international group of contributors has been updated and expanded, reflecting the newest treatments for pediatric and adult epilepsy. Seven sections with 30 chapters encompass surgical planning, invasive EEG studies, cortical resection, intraoperative mapping, disconnection, neuromodulation, and further topics. Twelve cortical resection chapters cover surgical approaches such as amygdalohippocampectomy; hippocampal transection; frontal lobe, central region, and posterior quadrant resections; and microsurgery versus endoscopy for hypothalamic hamartomas. Disconnection procedures discussed in section five include corpus callosotomy, hemispherectomy, and endoscopic-assisted approaches. Well-established procedures such as vagus nerve and deep brain stimulation are covered in the neuromodulation section, while the last section discusses radiosurgery for medically intractable cases. Key Highlights Chapters new to this edition include endoscopic callosotomy, laser-induced thermal therapy (LITT), and focused ultrasound High-quality illustrations, superb operative and cadaver photographs, radiologic images, and tables enhance understanding of impacted anatomy and specific techniques The addition of videos provides insightful step-by-step procedural guidance This is an essential reference for fellows and residents interested in epilepsy and functional neurosurgery, and an ideal overview for neurosurgeons, neurologists, and neuroradiologists in early career stages who wish to pursue this subspecialty.

Diagnosis and Surgical Treatment of Epilepsy

Author : Warren W. Boling
Publisher : MDPI
ISBN 13 : 3038974498
Total Pages : 136 pages
Book Rating : 4.0/5 (389 download)

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Book Synopsis Diagnosis and Surgical Treatment of Epilepsy by : Warren W. Boling

Download or read book Diagnosis and Surgical Treatment of Epilepsy written by Warren W. Boling and published by MDPI. This book was released on 2019-01-09 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Diagnosis and Surgical Treatment of Epilepsy" that was published in Brain Sciences

Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease

Author : Roger N. Rosenberg
Publisher : Elsevier
ISBN 13 : 0124105491
Total Pages : 1465 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease by : Roger N. Rosenberg

Download or read book Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease written by Roger N. Rosenberg and published by Elsevier. This book was released on 2014-10-28 with total page 1465 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rosenberg’s Molecular and Genetic Basis of Neurologic and Psychiatric Disease, Fifth Edition provides a comprehensive introduction and reference to the foundations and key practical aspects relevant to the majority of neurologic and psychiatric disease. A favorite of over three generations of students, clinicians and scholars, this new edition retains and expands the informative, concise and critical tone of the first edition. This is an essential reference for general medical practitioners, neurologists, psychiatrists, geneticists, and related professionals, and for the neuroscience and neurology research community. The content covers all aspects essential to the practice of neurogenetics to inform clinical diagnosis, treatment and genetic counseling. Every chapter has been thoroughly revised or newly commissioned to reflect the latest scientific and medical advances by an international team of leading scientists and clinicians. The contents have been expanded to include disorders for which a genetic basis has been recently identified, together with abundant original illustrations that convey and clarify the key points of the text in an attractive, didactic format. Previous editions have established this book as the leading tutorial reference on neurogenetics. Researchers will find great value in the coverage of genomics, animal models and diagnostic methods along with a better understanding of the clinical implications. Clinicians will rely on the coverage of the basic science of neurogenetics and the methods for evaluating patients with biochemical abnormalities or gene mutations, including links to genetic testing for specific diseases. Comprehensive coverage of the neurogenetic foundation of neurological and psychiatric disease Detailed introduction to both clinical and basic research implications of molecular and genetic understanding of the brain Detailed coverage of genomics, animal models and diagnostic methods with new coverage of evaluating patients with biochemical abnormalities or gene mutations

Epilepsy and the Corpus Callosum

Author : Alexander G. Reeves
Publisher : Springer Science & Business Media
ISBN 13 : 146132419X
Total Pages : 532 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Epilepsy and the Corpus Callosum by : Alexander G. Reeves

Download or read book Epilepsy and the Corpus Callosum written by Alexander G. Reeves and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: InJuly 1982 the first Dartmouth workshop on the corpus callosum took place. A nucleus of basic and clinical scientists was convened to give progress reports of their work on the corpus callosum. This text was subsequently compiled by the various participants from these reports modified by a stimulating cross fertilization of ideas and subsequent studies. Four and one-half decades have intervened since Van Wagenen first sectioned the corpus callosum for epilepsy (Van Wagenen and Herren, 1940) and Erickson (1940) demonstrated that the corpus callosum is the major route for generalization of experimentally induced focal cortical epilepsy. During the succeeding 45 years a handful of clinicians has pursued these leads to confirm the therapeutic value of callosotomy for some types of medically intractable generalized epilepsy. Parallel experimental studies with a number of epilepsy models have indicated that the corpus callosum is indeed the major route for seizure generalization, that the brainstem is a secondary and more resistant pathway for seizure generalization, and that most if not all epileptic seizures originate from the cerbral cortex. The unexpected clinical finding that even partial (focal) seizure incidence is modified by callosotomy now has been demonstrated in the laboratory. The various contributors to the clinical and experimental epilepsy sections of this volume have been seminal in these elucidations, as will be evident from their chapters. The section on the development, anatomy, and physiology of the corpus callosum demonstrates that these basic areas of study have not been neglected.

Translational Research in Traumatic Brain Injury

Author : Daniel Laskowitz
Publisher : CRC Press
ISBN 13 : 1498766579
Total Pages : 412 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Translational Research in Traumatic Brain Injury by : Daniel Laskowitz

Download or read book Translational Research in Traumatic Brain Injury written by Daniel Laskowitz and published by CRC Press. This book was released on 2015-12-01 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the development of new diagnostic and therapeutic approaches has been disappointingly slow. Translational Research in Traumatic Brain Injury attempts to integrate expertise from across specialties to address knowledge gaps in the field of TBI. Its chapters cover a wide scope of TBI research in five broad areas: Epidemiology Pathophysiology Diagnosis Current treatment strategies and sequelae Future therapies Specific topics discussed include the societal impact of TBI in both the civilian and military populations, neurobiology and molecular mechanisms of axonal and neuronal injury, biomarkers of traumatic brain injury and their relationship to pathology, neuroplasticity after TBI, neuroprotective and neurorestorative therapy, advanced neuroimaging of mild TBI, neurocognitive and psychiatric symptoms following mild TBI, sports-related TBI, epilepsy and PTSD following TBI, and more. The book integrates the perspectives of experts across disciplines to assist in the translation of new ideas to clinical practice and ultimately to improve the care of the brain injured patient.

Neurohospitalist Medicine

Author : S. Andrew Josephson
Publisher : Cambridge University Press
ISBN 13 : 1139501828
Total Pages : pages
Book Rating : 4.1/5 (395 download)

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Book Synopsis Neurohospitalist Medicine by : S. Andrew Josephson

Download or read book Neurohospitalist Medicine written by S. Andrew Josephson and published by Cambridge University Press. This book was released on 2011-09-29 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade, the hospitalist model has become a dominant system for the delivery of inpatient care. Forces such as national mandates to improve safety and quality, and intense pressure to safely reduce length of hospital stays, are now exerting pressure on neurologists. To meet these challenges, a new neurohospitalist model is emerging. This is the first authoritative text to detail the advances and strategies for treating neurologic disease in a hospital setting. It includes chapters on specific acute neurologic diseases including stroke, epilepsy, neuromuscular disease and traumatic brain injury and also addresses common reasons for neurologic consultation in the hospital including encephalopathy, electrolyte disturbances and neurologic complications of pregnancy. Ethical and structural issues commonly encountered in neurologic inpatients are also addressed. This will be a key resource for any clinician or trainee caring for neurologic patients in the hospital including practising neurologists, internists and trainees across multiple subspecialities.