Precision medicine approaches for heterogeneous conditions such as autism spectrum disorders (The need for a biomarker exploration phase in clinical trials - Phase 2m)

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2832515681
Total Pages : 153 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Precision medicine approaches for heterogeneous conditions such as autism spectrum disorders (The need for a biomarker exploration phase in clinical trials - Phase 2m) by : David Quentin Beversdorf

Download or read book Precision medicine approaches for heterogeneous conditions such as autism spectrum disorders (The need for a biomarker exploration phase in clinical trials - Phase 2m) written by David Quentin Beversdorf and published by Frontiers Media SA. This book was released on 2023-04-17 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many therapeutic interventions for autism spectrum disorder fail when they are examined in a clinical trial. Frequently, there is a subset of patients that responds very well to the intervention, while others do not, and the overall result does not yield a positive result. As autism spectrum disorder is highly heterogeneous in its underlying genetics and other etiological risk factors, as well as its heterogeneous phenotypic manifestation, this variability in response to any specific treatment is not entirely surprising. However, it remains a challenge to meaningfully subtype this heterogeneity for targeted treatment. The purpose of this research topic is to solicit articles that address the heterogeneity in autism spectrum disorder in a manner that may meaningfully contribute to targeted treatment approaches. Studies that address the heterogeneity of autism that could theoretically lead to targeted treatment, and studies that more directly address the use of a marker in association with response to a treatment, are both aspects that will contribute to this purpose. It is hoped that this Research Topic will yield articles that can help advance the field towards precision medicine in autism spectrum disorders. Manuscripts that contribute to the specification of the heterogeneity of autism spectrum disorder in a manner that could theoretically lead to targeted treatment would be appropriate for this research topic. Additionally, articles that utilize subtyping in relation to response to treatment would be appropriate for this research topic.

New Ways of Understanding Autism

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Author :
Publisher : Dundurn
ISBN 13 : 1459743628
Total Pages : 132 pages
Book Rating : 4.4/5 (597 download)

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Book Synopsis New Ways of Understanding Autism by : Brigitte Harrisson

Download or read book New Ways of Understanding Autism written by Brigitte Harrisson and published by Dundurn. This book was released on 2019-03-16 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: A new understanding of autism spectrum disorder. The experience of autistic people, real-life stories from parents, and suggested therapeutic approaches are brought together in New Ways of Understanding Autism to provide a realistic sense of autism and to build a sense of hope. Co-authors Brigitte Harrisson and Lise St-Charles, along with Governor General–award winning novelist Kim Thúy, present a new understanding of autism spectrum disorder — one that focuses on putting the needs of the autistic person where they should be: at the centre.

Towards an Ethic of Autism

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Author :
Publisher : Open Book Publishers
ISBN 13 : 1800642334
Total Pages : 194 pages
Book Rating : 4.8/5 (6 download)

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Book Synopsis Towards an Ethic of Autism by : Kristien Hens

Download or read book Towards an Ethic of Autism written by Kristien Hens and published by Open Book Publishers. This book was released on 2021-07-07 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kristien Hens succeeds in weaving together experiential expertise of both people with autism and their parents, scientific insights and ethics, and does so with great passion and affection for people with autism (with or without mental or other disabilities). In this book she not only asks pertinent questions, but also critically examines established claims that fail to take into account the criticism and experiences of people with autism. Sam Peeters, author of Autistic Gelukkig (Garant, 2018) and Gedurfde vragen (Garant, 2020); blog @ Tistje.com What does it mean to say that someone is autistic? Towards an Ethics of Autism is an exploration of this question and many more. In this thoughtful, wide-ranging book, Kristien Hens examines a number of perspectives on autism, including psychiatric, biological, and philosophical, to consider different ways of thinking about autism, as well as its meanings to those who experience it, those who diagnose it, and those who research it. Hens delves into the history of autism and its roots in the work of Leo Kanner and Hans Asperger to inform a contemporary ethical analysis of the models we use to understand autism today. She explores the various impacts of a diagnosis on autistic people and their families, the relevance of disability studies, the need to include autistic people fully in discussions about (and research on) autism, and the significance of epigenetics to future work on autism. Hens weaves together a variety of perspectives that guide the reader in their own ethical reflections about autism. Rich, accessible, and multi-layered, this is essential reading for philosophers, educational scientists, and psychologists who are interested in philosophical-ethical questions related to autism, but it also has much to offer to teachers, allied health professionals, and autistic people themselves.

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Author :
Publisher : Odile Jacob
ISBN 13 : 2738187145
Total Pages : 252 pages
Book Rating : 4.7/5 (381 download)

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Book Synopsis by :

Download or read book written by and published by Odile Jacob. This book was released on with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt:

New treatment perspectives in autism spectrum disorders

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889195309
Total Pages : 162 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis New treatment perspectives in autism spectrum disorders by : Roberto Canitano

Download or read book New treatment perspectives in autism spectrum disorders written by Roberto Canitano and published by Frontiers Media SA. This book was released on 2015-04-17 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developing novel and more effective treatments that improve quality of life for individuals with autism spectrum disorders is urgently needed. To date a wide range of behavioral interventions have been shown to be safe and effective for improving language and cognition and adaptive behavior in children and adolescents with ASD. However many people with ASD can receive additional benefit from targeted pharmacological interventions. One of the major drawback in setting up therapeutics intervention is the remarkable individual differences found across individuals with ASD. As a matter of fact the medications that are currently available address only symptoms associated with ASD and not the core domains of social and communication dysfunction. The pathogenesis paradigm shift of ASD towards synaptic abnormalities moved the research to pathway to disease that involve multiple systems and that are becoming the forefront of ASD treatment and are pointing toward the development of new targeted treatments. Some new therapeutics have been tested and others are being studied. In this context single gene disorders frequently associated with ASD such as Rett Syndrome, Fragile X and Tuberous Sclerosis have been of significant aid as neurobiology of these disorders is more clear and has a potential to shed light on the altered signaling in ASD. However much research is needed to further understand the basic mechanisms of disease and the relationship to idiopathic ASD. Clinical trials in children are underway with agents directed to core symptoms and to the associated disorders in the search of new therapeutics and progress are expected with possible new option for therapeutics in ASD in the upcoming future. Children and Adolescents with ASD and their families can provide important information about their experience with new treatments and this should be a priority for future research. In addition, research performed on genetic mouse models of ASD will keep on providing useful information on the molecular pathways dysrupted in the disease, thus contributing to identify novel drug targets.

An Early Start for Your Child with Autism

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Author :
Publisher : Guilford Press
ISBN 13 : 160918470X
Total Pages : 354 pages
Book Rating : 4.6/5 (91 download)

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Book Synopsis An Early Start for Your Child with Autism by : Sally J. Rogers

Download or read book An Early Start for Your Child with Autism written by Sally J. Rogers and published by Guilford Press. This book was released on 2012-05-21 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents strategies for helping children with autism interact with others and achieve their potential, covering such areas as back-and-forth interactions, nonverbal communication, and imitation.

Why We Need More Canadian Health Policy in the Media

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Author :
Publisher : EvidenceNetwork.ca
ISBN 13 : 0995157324
Total Pages : 351 pages
Book Rating : 4.9/5 (951 download)

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Book Synopsis Why We Need More Canadian Health Policy in the Media by : Noralou Roos

Download or read book Why We Need More Canadian Health Policy in the Media written by Noralou Roos and published by EvidenceNetwork.ca. This book was released on 2016-06-21 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: Why We Need More Canadian Health Policy in the Media is a compilation of health policy commentaries published by EvidenceNetwork.ca experts in major newspapers in 2015. These articles highlight the most recent evidence on a wide range of health policy topics, including our aging population, healthcare costs and spending, mental health, pharmaceutical policy, the social determinants of health and distinctions between the Canadian and American healthcare system among other topics. This is the fourth volume in the annual series of eBooks produced by EvidenceNetwork.ca, the first being Canadian Health Policy in the News (2013), followed by Making Evidence Matter in Canadian Health Policy (2014) and Navigating the Evidence: Communicating Canadian Health Policy in the Media (2015). We acknowledge the Canadian Institutes for Health Research, Research Manitoba, the Manitoba Centre for Health Policy, the George and Fay Yee Centre for Healthcare Innovation, CIHR’s Institute of Health Services and Policy Research, and their Institute of Population and Public Health, The Canadian Frailty Network, and the University of Manitoba’s Department of Community Health Sciences and Max Rady College of Medicine whose funding supports EvidenceNetwork.ca.

The TEACCH Approach to Autism Spectrum Disorders

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 0306486474
Total Pages : 213 pages
Book Rating : 4.3/5 (64 download)

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Book Synopsis The TEACCH Approach to Autism Spectrum Disorders by : Gary B. Mesibov

Download or read book The TEACCH Approach to Autism Spectrum Disorders written by Gary B. Mesibov and published by Springer Science & Business Media. This book was released on 2010-02-23 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: - Professionals can be trained in the program and its methods - Translates scientific knowledge so that practitioners and parents can easily understand the current state of knowledge - Offers strategies that can be tailored to an individual's unique developmental and functional level - Advises parents on how to become involved in all phases of intervention as collaborators, co-therapists, and advocates. - Details how the program can be introduced and adapted for individuals of all ages, from preschooler to adult

Signs of Autism in Infants

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Author :
Publisher : Routledge
ISBN 13 : 0429919247
Total Pages : 228 pages
Book Rating : 4.4/5 (299 download)

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Book Synopsis Signs of Autism in Infants by : Stella Acquarone

Download or read book Signs of Autism in Infants written by Stella Acquarone and published by Routledge. This book was released on 2018-03-26 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: As a group, babies later diagnosed as autistic are found to have more complications during gestation and delivery than their normal siblings and others. In addition to all these complications, infants later diagnosed on the autistic spectrum have a two-fold rate of residence in neonatal intensive care units. Over the past 50 years, ever younger previously non-viable very low weight babies are being kept alive, some born as much as four months before term. However, it is becoming apparent that miraculous procedures to counteract organ immaturity and prolonged incubation contribute to a new gamut of hitherto unknown forms of neurological damage. With pregnancy curtailed, prematurely separated mothers and their babies both experience a prolonged state of limbo, with the fragile infant being exposed to excruciating medical interventions and overwhelming stimulation. International researchers and clinicians renowned for their work in the field of early autism come together to resolve queries around the long debate on the development and resolution of autism.

L'intervention précoce en autisme pour les parents

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Author :
Publisher : Dunod
ISBN 13 : 2100816721
Total Pages : 380 pages
Book Rating : 4.1/5 (8 download)

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Book Synopsis L'intervention précoce en autisme pour les parents by : Sally J. Rogers

Download or read book L'intervention précoce en autisme pour les parents written by Sally J. Rogers and published by Dunod. This book was released on 2020-07-01 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: L’autisme est un trouble neurodéveloppemental dont l’impact sur l’évolution de l’enfant est très lourd. La précocité du diagnostic et de la mise en place d’une intervention adaptée conditionnent beaucoup la progression de l’enfant et son accès à une meilleure qualité de vie. Le Early Start Denver Model (ESM) est une approche développementale et comportementale qui met l’accent sur l’apprentissage dans un contexte socio-émotionnel positif. Ce programme a donc été conçu pour répondre aux besoins spécifiques de très jeunes enfants et pour une stimulation optimale de leurs compétences. L’objectif de ce livre est de fournir aux parents et à l'entourage des outils et des stratégies pour aider l'enfant atteint d'autisme à retrouver une trajectoire de développement positive aussi vite que possible.

Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie

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Publisher :
ISBN 13 :
Total Pages : 670 pages
Book Rating : 4.:/5 ( download)

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Book Synopsis Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie by :

Download or read book Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie written by and published by . This book was released on 2006 with total page 670 pages. Available in PDF, EPUB and Kindle. Book excerpt:

L'intervention précoce en autisme - Modèle de Denver pour les groupes d'enfants d'âge préscolaire

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Author :
Publisher : Dunod
ISBN 13 : 2100873059
Total Pages : 404 pages
Book Rating : 4.1/5 (8 download)

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Book Synopsis L'intervention précoce en autisme - Modèle de Denver pour les groupes d'enfants d'âge préscolaire by : Giacomo Vivanti

Download or read book L'intervention précoce en autisme - Modèle de Denver pour les groupes d'enfants d'âge préscolaire written by Giacomo Vivanti and published by Dunod. This book was released on 2024-06-19 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: L'intervention précoce en autisme avec le modèle de Denver (Early Start Denver Model - ESDM) s'effectue initialement de façon individuelle (1 enfant / 1 intervenant). Ce livre est une adaptation de ce modèle pour être utilisé avec des enfants d'âge préscolaire (avant l’entrée à l’école primaire, de 1 an à 5 ans) dans le cadre d’un groupe. La ligne directrice du modèle (Group-Based Early Start Denver Model - G-ESDM) est de construire les bases d'un apprentissage social spontané afin que l'enfant puisse apprendre des autres dans toutes les expériences et contextes quotidiens, comme le font les autres enfants. L’ouvrage décrit les principes et les procédures de ce modèle, fournit les directives pour la mise en œuvre de programmes efficaces dans les établissements de santé publics et éducatifs. Les chapitres contiennent des stratégies pour concevoir et évaluer des interventions, constituer des équipes interdisciplinaires et organiser des espaces d'apprentissage.

Journal of Speech-language Pathology and Audiology

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Publisher :
ISBN 13 :
Total Pages : 450 pages
Book Rating : 4.3/5 (555 download)

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Book Synopsis Journal of Speech-language Pathology and Audiology by :

Download or read book Journal of Speech-language Pathology and Audiology written by and published by . This book was released on 2002 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Coaching Parents of Young Children with Autism

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Publisher : Guilford Publications
ISBN 13 : 1462545742
Total Pages : 338 pages
Book Rating : 4.4/5 (625 download)

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Book Synopsis Coaching Parents of Young Children with Autism by : Sally J. Rogers

Download or read book Coaching Parents of Young Children with Autism written by Sally J. Rogers and published by Guilford Publications. This book was released on 2021-03-12 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: A growing body of evidence supports the benefits of high-quality parent interventions for building social and communication skills in 0- to 5-year-olds with autism spectrum disorder (ASD). How can clinicians coach parents to effectively incorporate learning opportunities into daily routines at home? From preeminent experts, this practical book explores the role of the coach and reviews the "whats," "whys," and "how-tos" of successful collaboration with parents. Topics include structuring coaching sessions, identifying children's needs, facilitating playful engagement, and deepening parents' understanding of how they can boost skills development during everyday activities. Seventeen reproducible handouts and forms include the multipage P-ESDM Infant–Toddler Curriculum Checklist, ideal for use in telehealth assessments. Purchasers get access to a webpage where they can download and print the reproducible materials in a convenient 8 1/2" x 11" size.

American Journal of Mental Retardation

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Author :
Publisher :
ISBN 13 :
Total Pages : 528 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis American Journal of Mental Retardation by :

Download or read book American Journal of Mental Retardation written by and published by . This book was released on 2008 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Includes the association's conference proceedings and addresses.

L'intervention précoce en autisme

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Author :
Publisher :
ISBN 13 : 9782100862436
Total Pages : 0 pages
Book Rating : 4.8/5 (624 download)

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Book Synopsis L'intervention précoce en autisme by : Giacomo Vivanti

Download or read book L'intervention précoce en autisme written by Giacomo Vivanti and published by . This book was released on 2024-06-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Children with Autism

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Author :
Publisher : Jessica Kingsley Publishers
ISBN 13 : 9781853025556
Total Pages : 374 pages
Book Rating : 4.0/5 (255 download)

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Book Synopsis Children with Autism by : Colwyn Trevarthen

Download or read book Children with Autism written by Colwyn Trevarthen and published by Jessica Kingsley Publishers. This book was released on 1998 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: This completely revised and substantially expanded new edition embraces new developments in this rapidly developing field. Every chapter has been rewritten with the addition of new material, and a new final chapter on `Putting the Pieces Together' reflects the authors' conviction that the complexity of autism means that many kinds of information are valuable and need to be taken into account in providing therapy or teaching for children with autism. Other chapters, updated from the first edition, include a description of the latest information on the findings of brain research (put into the context of the development of the human brain and its effect on communication in early childhood), and the contributions of music therapy and psychoanalysis. A very much enlarged chapter on educational provision for children with autism and Asperger's Syndrome provides information on the latest methods for improving the learning of these children, to give them the best possible preparation for a life of greater autonomy and maximum self-satisfaction in the pleasure of human company. New appendices summarise medical diagnostic systems, checklists and questionnaires for identifying autism, and the glossary has been considerably expanded. The wealth of up-to-date information provided will be invaluable not only for researchers and students but also for psychologists, teachers and other professionals, and parents, carers and family members in search of comprehensive and helpful information.