The Interferon System

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Publisher : Springer Science & Business Media
ISBN 13 : 3709134323
Total Pages : 432 pages
Book Rating : 4.7/5 (91 download)

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Book Synopsis The Interferon System by : W.E. Stewart II

Download or read book The Interferon System written by W.E. Stewart II and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an update of Interferon, published in 1969 by Dr. Jan Vilcek. The field of interferon research has since expanded from its former narrow treatment of interferon strictly as an antiviral substance, such that The Interferon System now encompasses cellular modulations ranging from immune alterations to cell proliferative restrictions to antitumor activities. The steadily increasing number of these non-antiviral functions of interferons emphasizes the need for a comprehensive - and critical - review of the entire literature of interferon studies. The text, with its supporting bibliography, provides complete coverage of interferon research. A newcomer to the area should find here all the informa tion necessary to understand why interferon, which has been studied for more than twenty years and which originally stirred excitement over its clinical pros pects, is still inspiring speculation about this potential. For those already fa miliar with the seemingly perpetual clinical promise of interferon, this volume should serve as a valuable reference source, the largest bibliography on the subject ever to appear under one cover. Clearly, this book should be considered only as an introduction to the topic and as a reference source; most questions about the interferon system are still unanswered - even unasked. Hopefully this summation and critical evalua tion of work done to date will stimulate and facilitate further progress. William E. Stewart II New York, N. Y., February 1979 Contents I. Introduction ............................................................. .

Hepatotoxicity

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Publisher : Lippincott Williams & Wilkins
ISBN 13 : 9780781719520
Total Pages : 848 pages
Book Rating : 4.7/5 (195 download)

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Book Synopsis Hepatotoxicity by : Hyman J. Zimmerman

Download or read book Hepatotoxicity written by Hyman J. Zimmerman and published by Lippincott Williams & Wilkins. This book was released on 1999 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.

Interferon Therapy of Multiple Sclerosis

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Publisher : CRC Press
ISBN 13 : 9780824797645
Total Pages : 574 pages
Book Rating : 4.7/5 (976 download)

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Book Synopsis Interferon Therapy of Multiple Sclerosis by : Anthony Reder

Download or read book Interferon Therapy of Multiple Sclerosis written by Anthony Reder and published by CRC Press. This book was released on 1997-01-28 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference presents cutting-edge basic and clinical research on all forms of interferon (IFN) involvement in the management of multiple sclerosis (MS)-detailing topics from IFN-receptor molecular interactions to synergy and interference with other agents such as cytotoxic drugs and chemotherapy. Features detailed research findings on IFN ß -1a (Avonex) and IFN -1b (Betaseron).

The Interferons

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Publisher : John Wiley & Sons
ISBN 13 : 3527607927
Total Pages : 460 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis The Interferons by : Anthony Meager

Download or read book The Interferons written by Anthony Meager and published by John Wiley & Sons. This book was released on 2006-08-21 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: At long last, the first book to cover all important areas of interferon science in one volume. Top scientists, including many pioneers in the field, highlight the role of interferons as research tools and as therapeutic agents in clinical applications. Edited by an experienced interferonologist, chapters include discussions of interferon genes, Type I, II and III IFNs, as well as their induction, production and purification, receptors actions, measuring IFN activities and anti-IFN antibodies, as well as the evolution of viral defense mechanisms. For immunologists, cancer researchers, medicinal chemists, cell biologists, developmental biologists and the pharmaceutical industry.

Drug-Induced Liver Disease

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Publisher : CRC Press
ISBN 13 : 0203909127
Total Pages : 790 pages
Book Rating : 4.2/5 (39 download)

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Book Synopsis Drug-Induced Liver Disease by : Neil Kaplowitz

Download or read book Drug-Induced Liver Disease written by Neil Kaplowitz and published by CRC Press. This book was released on 2002-10-16 with total page 790 pages. Available in PDF, EPUB and Kindle. Book excerpt: Featuring more than 4100 references, Drug-Induced Liver Disease will be an invaluable reference for gastroenterologists, hepatologists, family physicians, internists, pathologists, pharmacists, pharmacologists, and clinical toxicologists, and graduate and medical school students in these disciplines.

Coronaviruses and Arteriviruses

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Publisher : Springer Science & Business Media
ISBN 13 : 9780306459108
Total Pages : 858 pages
Book Rating : 4.4/5 (591 download)

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Book Synopsis Coronaviruses and Arteriviruses by : Luis Enjuanes

Download or read book Coronaviruses and Arteriviruses written by Luis Enjuanes and published by Springer Science & Business Media. This book was released on 1998-08-31 with total page 858 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the VIIth International Symposium held in Segovia, Spain, May 10-15, 1997

Viruses and Man: A History of Interactions

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Publisher : Springer
ISBN 13 : 3319077589
Total Pages : 433 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Viruses and Man: A History of Interactions by : Milton W. Taylor

Download or read book Viruses and Man: A History of Interactions written by Milton W. Taylor and published by Springer. This book was released on 2014-07-21 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Milton Taylor, Indiana University, offers an easy-to-read and fascinating text describing the impact of viruses on human society. The book starts with an analysis of the profound effect that viral epidemics had on world history resulting in demographic upheavals by destroying total populations. It also provides a brief history of virology and immunology. Furthermore, the use of viruses for the treatment of cancer (viral oncolysis or virotherapy) and bacterial diseases (phage therapy) and as vectors in gene therapy is discussed in detail. Several chapters focus on viral diseases such as smallpox, influenza, polio, hepatitis and their control, as well as on HIV and AIDS and on some emerging viruses with an interesting story attached to their discovery or vaccine development. The book closes with a chapter on biological weapons. It will serve as an invaluable source of information for beginners in the field of virology as well as for experienced virologists, other academics, students, and readers without prior knowledge of virology or molecular biology.

Recent Advances in Bone Tumours and Osteoarthritis

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Publisher : BoD – Books on Demand
ISBN 13 : 1839689234
Total Pages : 154 pages
Book Rating : 4.8/5 (396 download)

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Book Synopsis Recent Advances in Bone Tumours and Osteoarthritis by : Hiran Amarasekera

Download or read book Recent Advances in Bone Tumours and Osteoarthritis written by Hiran Amarasekera and published by BoD – Books on Demand. This book was released on 2021-09-01 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a combination of recent advances in two major areas of orthopaedics: Bone tumours and Osteoarthritis. All chapters are contributed by well-known researchers and surgeons in Orthopaedics working across the globe. The book is divided into two major parts for clarity. All authors have contributed their original research, their experience in the field, and the recent advances that will keep the reader well informed and up to date in our understanding of bone tumours and osteoarthritis. This is a “must have” reference book for any medical library or an individual who is keen to update and have CME (continuous medical education) points added to their learning.

Dubois' Lupus Erythematosus and Related Syndromes - E-Book

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Publisher : Elsevier Health Sciences
ISBN 13 : 0323550649
Total Pages : 752 pages
Book Rating : 4.3/5 (235 download)

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Book Synopsis Dubois' Lupus Erythematosus and Related Syndromes - E-Book by : Daniel Wallace

Download or read book Dubois' Lupus Erythematosus and Related Syndromes - E-Book written by Daniel Wallace and published by Elsevier Health Sciences. This book was released on 2018-08-16 with total page 752 pages. Available in PDF, EPUB and Kindle. Book excerpt: For more than 50 years, Dubois’ Lupus Erythematosus and Related Syndromes has been recognized internationally as the go-to clinical reference on lupus and other connective tissue diseases. From basic scientific principles to practical points of clinical management, the updated 9th Edition provides extensive, authoritative coverage of systemic lupus erythematosus (SLE) and its related diseases in a logical, clearly written, user-friendly manner. It’s an ideal resource for rheumatologists and internal medicine practitioners who need a comprehensive clinical reference on all aspects of SLE, connective tissue diseases, and the antiphospholipid syndromes. Provides complete clinical coverage of every aspect of cutaneous and systemic lupus erythematosus, including definitions, pathogenesis, autoantibodies, clinical and laboratory features, management, prognosis, and patient education. Contains an up-to-date overview of significant advances in cellular, molecular, and genetic technologies, including genetic advancements in identifying at-risk patients. Offers an increased focus on the clinical management of related disorders such as Sjogren’s syndrome, scleroderma, polymyositis, and antiphospholipid syndrome (APS). Presents the knowledge and expertise of more international contributors to provide new global perspectives on manifestations, diagnosis, and treatment. Features a vibrant, full-color format, with graphs, algorithms, differential diagnosis comparisons, and more schematic diagrams throughout.

Interferon: The 50th Anniversary

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Publisher : Springer Science & Business Media
ISBN 13 : 354071328X
Total Pages : 767 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Interferon: The 50th Anniversary by : Paula M. Pitha

Download or read book Interferon: The 50th Anniversary written by Paula M. Pitha and published by Springer Science & Business Media. This book was released on 2007-09-11 with total page 767 pages. Available in PDF, EPUB and Kindle. Book excerpt: A vital text for researchers and clinicians in the fields of virology and oncology alike, this book is a comprehensive guide to one of medicine’s most important tools that covers the most recent research. Important insights have been made in recent months that are challenging the accepted concept of the critical role of dsRNA in IFN induction. Recent work with genetically modified mice seems to confirm the original idea that interferon is the first cellular defense against viral infection.

Molecular and Cellular Changes in the Cancer Cell

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Publisher : Academic Press
ISBN 13 : 0128096039
Total Pages : 616 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Molecular and Cellular Changes in the Cancer Cell by :

Download or read book Molecular and Cellular Changes in the Cancer Cell written by and published by Academic Press. This book was released on 2016-11-16 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular and Cellular Changes in the Cancer Cell,the latest volume in the Progress in Molecular Biology and Translational Science series, includes a comprehensive summary of the evidence accumulated thus far on the molecular and cellular regulation of the various adaptations taking place in response to exercise. This volume examines some of the latest advances, highlighting some of the most important molecular and cellular alterations and environmental influences that collectively cause a normal cell to become cancerous. Special emphasis is given to changes that take place at the molecular and cellular level. Comprehensive and up-to-date survey of current knowledge on the cancer cell Includes the latest advances and the most important molecular and cellular alterations and environmental influences collectively causing cells to become cancerous Written by leading experts in the field

Interferons

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Publisher : Springer Science & Business Media
ISBN 13 : 3642604110
Total Pages : 302 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Interferons by : Carlo Aul

Download or read book Interferons written by Carlo Aul and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interferons were among the first cytokines to be studied clinically in recombinant form in the 1980s, beginning a new era of pharmacotherapy in internal medicine. Interferons were soon employed in the treatment of tumors and it was shown that those hematopoietic neoplasias which had been difficult to treat with chemotherapy responded well to interferon treatment. In the present volume, renowned international authors update the importance of interferons in various fields of internal medicine, dermatology, and urology. The book also contains a general introduction into the classification, structure, and mode of action of interferons. Further chapters discuss the range of side effects of these substances and point out possible focuses of further clinical interferon research.

Interferons

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Publisher : Elsevier
ISBN 13 : 0323147909
Total Pages : 504 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Interferons by : Thomas Merigan

Download or read book Interferons written by Thomas Merigan and published by Elsevier. This book was released on 2012-12-02 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interferons documents the proceedings of a major international conference on Chemistry and Biology of Interferons: Relationship to Therapeutics held at Squaw Valley, California, in March 1982. The meeting was one of the 1982 UCLA Symposia on Molecular and Cellular Biology organized through the Molecular Biology Institute of the University of California at Los Angeles. The book is organized into four parts. Part I presents papers on recombinant DNA production of interferon. It includes studies on the synthesis of human immune interferon in E. coli and monkey cells; the expression of human ß interferon gene in heterologous cells; and the molecular activities of recombinant and hybrid leukocyte interferons. Part II deals with the biology of interferons, covering topics such as interferon production control process; the effect of interferon on cellular enzymes; and human amniotic interferon. Part III examines the factors relevant to clinical application of interferons, including structure-function studies with human interferon-gamma and on human alpha interferon. Part IV presents clinical studies of interferon, such as interferon a trials in human tumor diseases and interferon in renal transplant recipients.

Innate Immunity in Health and Disease

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Publisher : BoD – Books on Demand
ISBN 13 : 1838807659
Total Pages : 416 pages
Book Rating : 4.8/5 (388 download)

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Book Synopsis Innate Immunity in Health and Disease by : Shailendra K. Saxena

Download or read book Innate Immunity in Health and Disease written by Shailendra K. Saxena and published by BoD – Books on Demand. This book was released on 2021-08-25 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book focuses on various aspects and properties of innate immunity, whose deep understanding is integral for safeguarding the human race from further loss of resources and economies due to innate immune response-mediated diseases. Throughout this book, we examine the individual mechanisms by which the innate immune response acts to protect the host from pathogenic infectious agents and other non-communicable diseases. Written by experts in the field, the volume discusses the significance of macrophages in infectious disease, tumor metabolism, and muscular disorders. Chapters cover such topics as the fate of differentiated macrophages and the molecular pathways that are important for the pathologic role of macrophages.

Interferons and Their Applications

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Publisher : Springer Science & Business Media
ISBN 13 : 3642691781
Total Pages : 585 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Interferons and Their Applications by : P.E. Came

Download or read book Interferons and Their Applications written by P.E. Came and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 585 pages. Available in PDF, EPUB and Kindle. Book excerpt: Today, the basic mood of researchers and clinical investigators, both at the center and on the periphery of interferon studies, is optimistic regarding the future of interferons as therapeutic substances. Many also feel these polypeptides will prove invaluable probes in unraveling certain fundamental biochemical processes which control the life cycle and developmental pattern of many human cells. In contrast, only a year or two ago, this optimism had given way to an attitude almost of disenchantment as public and scientific expectations were raised steeply, then rapidly waned, as it turns out, prematurely. Both the mUltiple actions of interferons (a virtual cascade of biochemical reactions may be induced, as documented herein) and the high visibility of interferon research provided by the millions of dollars invested both by national health agencies and by multinational pharmaceutical companies, contributed to an upsweep in public attention to drug development probably unprecedented in this century. Virtually every oncologist, it would seem, was plagued by requests for the experimental agent, although they already had therapies of more proven value. As recently as 1980, even though interferon had achieved success against certain cancers and certain viral diseases, the variability in clinical results was seemingly ever present and little evidence emerged to suggest interferons could cure advanced diseases. Why then the resurgence of an optimistic mood? There are almost always many elements which contribute to happiness, and this is certainly true of the broad frontier of interferon and its place in biochemical research and treatment.

Interferons A Primer

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Publisher : Elsevier
ISBN 13 : 0323160859
Total Pages : 164 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Interferons A Primer by : Robert Friedman

Download or read book Interferons A Primer written by Robert Friedman and published by Elsevier. This book was released on 2012-12-02 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interferons: A Primer covers general information on interferon, including analysis, purification, production, properties, mechanism of action, and clinical uses. Organized into 10 chapters, the book starts with a short history of interferon’s discovery by Isaacs and Lindenmann, followed by topics on assays for interferon, such as factors affecting interferon assays and rapid biological assay. Chapters 3 to 6 discuss the purification, properties, production, antiviral action, and other functions of interferon. Chapters 7 and 8 examine the recovery from viral infection and clinical uses of interferon, with emphasis on treatment of human cancer. The concluding chapters focus on the application of interferon studies on two revolutionizing fields of biology, namely, the cloning of animal genes in microorganisms and the production of monoclonal antibodies. This book is intended for students, scientists, physicians, or educated laypersons who wish to know something about interferons, but do not plan carrying out research in this area.

Clinical Aspects of Interferons

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Publisher : Springer Science & Business Media
ISBN 13 : 1461317371
Total Pages : 377 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Clinical Aspects of Interferons by : Michel Revel

Download or read book Clinical Aspects of Interferons written by Michel Revel and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: