Interactions of Composite Gold Nanoparticles with Cells and Tissue

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ISBN 13 :
Total Pages : 274 pages
Book Rating : 4.:/5 (871 download)

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Book Synopsis Interactions of Composite Gold Nanoparticles with Cells and Tissue by : Justina Oichi Tam

Download or read book Interactions of Composite Gold Nanoparticles with Cells and Tissue written by Justina Oichi Tam and published by . This book was released on 2012 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current methods to diagnose and treat cancer often involve expensive, time-consuming equipment and materials that may lead to unwanted side effects and may not even increase a patient's chance of survival. Thus, for a while now, a large part of the research community has focused on developing improved methods to detect, diagnose, and treat cancer on the molecular scale. One of the most recently discovered methods of cancer therapy is targeted therapy. These targeted therapies have potential to provide a patient with a form of personalized medicine because these therapies are biological molecules that specifically target other molecules involved with a cancer's growth. Past trials using these therapeutic molecules, however, have led to controversial results, where certain patients responded better than others to the therapy for unknown reasons. Elucidating the reason behind these mixed results can be accomplished using metal nanoparticle technologies which could provide a bright signal to monitor the path that these therapeutic molecules take in vivo as well as enhance the molecule's efficacy. Literature has shown that presenting targeting molecules in a dense manner to their target will increase these molecules' binding affinity. This concept has been explored here to increase binding affinity of therapeutic molecules by attaching these molecules in a dense manner on the surface of gold nanoparticles, and correlating this increased affinity with therapeutic efficacy. Additionally, gold nanoparticles provide an easy surface for molecules to be functionalized on and have shown to be effective imaging, x-ray, and photothermal therapy agents. A major roadblock to using these gold nanoparticles clinically is their non-degradability and thus potential to cause long-term negative side effects in vivo. A platform for developing biodegradable gold nanoparticles is also explored here to take advantage of the gold nanoparticles' excellent imaging and drug delivery capabilities while still allowing them to be used safely in the long term.

Investigations of the Interaction of Gold Nanoparticles with Proteins, Cells, and Tissues

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (932 download)

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Book Synopsis Investigations of the Interaction of Gold Nanoparticles with Proteins, Cells, and Tissues by :

Download or read book Investigations of the Interaction of Gold Nanoparticles with Proteins, Cells, and Tissues written by and published by . This book was released on 2013 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Interaction of Nanomaterials With Living Cells

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Publisher : Springer Nature
ISBN 13 : 9819921198
Total Pages : 936 pages
Book Rating : 4.8/5 (199 download)

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Book Synopsis Interaction of Nanomaterials With Living Cells by : Faheem Arjamend Sheikh

Download or read book Interaction of Nanomaterials With Living Cells written by Faheem Arjamend Sheikh and published by Springer Nature. This book was released on 2023-11-10 with total page 936 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines the interactions of nanomaterials with the biological system. The chapters of the book explore the natural and synthetic biomaterials that modulate immune responses for their applications in drug delivery and tissue engineering. Further, the book discusses the implications of the physiochemical properties of nanoparticles and their microenvironment on their interactions with biological systems. The chapters also present the recognitive capabilities of biomaterials for the development of novel strategies for the detection and treatment of autoimmune disorders. The book also introduces nanotechnology platforms for drug delivery and highlights current and emerging nanotechnologies that could enable novel classes of therapeutics. Towards the end, the book reviews the efficiency of drug-loaded nanoparticles in modulating the functioning of the biological milieu for improved disease treatment. Lastly, the book outlines the ethical issues regarding the use of nanoparticles for in vitro and in vivo applications. Given its scope, it is a valuable resource for graduate students and researchers interested in understanding the biomedical applications of nanoparticles and their interactions with the biological milieu.

Cat's Away

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (68 download)

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Book Synopsis Cat's Away by :

Download or read book Cat's Away written by and published by . This book was released on 1850* with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Nanomedicine

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Publisher : Elsevier Inc. Chapters
ISBN 13 : 0128055413
Total Pages : 29 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Nanomedicine by : S.J. McMahon

Download or read book Nanomedicine written by S.J. McMahon and published by Elsevier Inc. Chapters. This book was released on 2013-09-19 with total page 29 pages. Available in PDF, EPUB and Kindle. Book excerpt: The physical mechanisms of action involved when heavy atoms are embedded in biological systems subject to ionising radiation are described with a particular view to providing models for the use of (gold) nanoparticles as targeted agents intended to improve both diagnostic imaging and radiotherapy. Fundamental interactions between ionising radiation and matter are reviewed and then invoked to describe the specific processes arising when nanoparticles containing heavy atoms, and particularly gold nanoparticles, are irradiated in biological systems. Shortcomings in simple macroscopic models of dose distribution are discussed, with the concept of nanodosimetry being used to account for the large effects observed. Finally, some open questions and future research directions are reviewed.

Handbook of Composites from Renewable Materials, Biodegradable Materials

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Publisher : John Wiley & Sons
ISBN 13 : 1119224381
Total Pages : 692 pages
Book Rating : 4.1/5 (192 download)

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Book Synopsis Handbook of Composites from Renewable Materials, Biodegradable Materials by : Vijay Kumar Thakur

Download or read book Handbook of Composites from Renewable Materials, Biodegradable Materials written by Vijay Kumar Thakur and published by John Wiley & Sons. This book was released on 2017-02-17 with total page 692 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique multidisciplinary 8-volume set focuses on the emerging issues concerning synthesis, characterization, design, manufacturing and various other aspects of composite materials from renewable materials and provides a shared platform for both researcher and industry. The Handbook of Composites from Renewable Materials comprises a set of 8 individual volumes that brings an interdisciplinary perspective to accomplish a more detailed understanding of the interplay between the synthesis, structure, characterization, processing, applications and performance of these advanced materials. The Handbook comprises 169 chapters from world renowned experts covering a multitude of natural polymers/ reinforcement/ fillers and biodegradable materials. Volume 5 is solely focused on 'Biodegradable Materials'. Some of the important topics include but not limited to: Rice husk and its composites; biodegradable composites based on thermoplastic starch and talc nanoparticles; recent progress in biocomposites of biodegradable polymer; microbial polyesters: production and market; biodegradable and bioabsorbable materials for osteosynthesis applications; biodegradable polymers in tissue engineering; composites based on hydroxyapatite and biodegradable polylactide; biodegradable composites; development of membranes from biobased materials and their applications; green biodegradable composites based on natural fibers; fully biodegradable all-cellulose composites; natural fiber composites with bioderivative and/or degradable polymers; synthetic biodegradable polymers for bone tissue engineering; polysaccharides as green biodegradable platforms for building up electroactive composite materials; biodegradable polymer blends and composites from seaweeds; biocomposites scaffolds derived from renewable resources for bone tissue repair; pectin-based composites; recent advances in conductive composites based on biodegradable polymers for regenerative medicine applications; biosynthesis of PHAs and their biomedical applications; biodegradable soy protein isolate/poly(vinyl alcohol) packaging films; and biodegradability of biobased polymeric materials in natural environment.

Nanostructures for the Engineering of Cells, Tissues and Organs

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Publisher : William Andrew
ISBN 13 : 0128136669
Total Pages : 631 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Nanostructures for the Engineering of Cells, Tissues and Organs by : Alexandru Mihai Grumezescu

Download or read book Nanostructures for the Engineering of Cells, Tissues and Organs written by Alexandru Mihai Grumezescu and published by William Andrew. This book was released on 2018-02-14 with total page 631 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanostructures for the Engineering of Cells: Tissues and Organs showcases recent advances in pharmaceutical nanotechnology, with particular emphasis on tissue engineering, organ and cell applications. The book provides an up-to-date overview of organ targeting and cell targeting using nanotechnology. In addition, tissue engineering applications, such as skin regeneration are also discussed. Written by a diverse range of international academics, this book is a valuable research resource for researchers working in the biomaterials, medical and pharmaceutical industries. - Explains how nanomaterials regulate different cell behavior and function as a carrier for different biomolecules - Shows how nanobiomaterials and nanobiodevices are used in a range of treatment areas, such as skin tissue, wound healing and bone regeneration - Discusses nanomaterial preparation strategies for pharmaceutical application and regenerative medicine

Carbon Nanotubes

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Publisher : CRC Press
ISBN 13 : 1000377504
Total Pages : 376 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Carbon Nanotubes by : Andy Nieto

Download or read book Carbon Nanotubes written by Andy Nieto and published by CRC Press. This book was released on 2021-05-18 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: This discovery of carbon nanotubes (CNT) three decades ago ushered in the technological era of nanotechnology. Among the most widely studied areas of CNT research is their use as structural reinforcements in composites. This book describes the development of CNT reinforced metal matrix composites (CNT-MMCs) over the last two decades. The field of CNT-MMCs is abundant in fundamental science, rich in engineering challenges and innovations and ripe for technological maturation and commercialization. The authors have sought to present the current state of the-art in CNT-MMC technology from their synthesis to their myriad potential end-use applications. Specifically, topics explored include: • Advantages, limitations, and evolution of processing techniques used to synthesize and fabricate CNT-MMCs • Emphasizes dispersion techniques of CNTs in metallic systems, a key challenge to the successful and widespread implementation of CNT-MMCs. Methods for quantification and improved control of CNT distributions are presented • Methods for quantification and improved control of CNT distributions are presented • Characterization techniques uniquely suited for charactering these nanoscale materials and their many chemical and physical interactions with the metal matrix, including real-time in-situ characterization of deformation mechanisms • Electron microscope images from premier studies enrich discussions on micro-mechanical modeling, interfacial design, mechanical behavior, and functional properties • A chapter is dedicated to the emergence of dual reinforcement composites that seek to enhance the efficacy of CNTs and lead to material properties by design This book highlights seminal findings in CNT-MMC research and includes several tables listing processing methods, associated CNT states, and resulting properties in order to aid the next generation of researchers in advancing the science and engineering of CNT-MMCs. In addition, a survey of the patent literature is presented in order to shed light on what the first wave of CNT-MMC commercialization may look like and the challenges that will have to be overcome, both technologically and commercially.

A Study of Gold Nanoparticles

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ISBN 13 :
Total Pages : 124 pages
Book Rating : 4.:/5 (14 download)

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Book Synopsis A Study of Gold Nanoparticles by : Kleanthis Fytianos

Download or read book A Study of Gold Nanoparticles written by Kleanthis Fytianos and published by . This book was released on 2014 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Surface Charge-mediated Interactions and Transport of Ultrasmall Gold Nanoparticles in the Normal and Diseased Kidney

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ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (135 download)

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Book Synopsis Surface Charge-mediated Interactions and Transport of Ultrasmall Gold Nanoparticles in the Normal and Diseased Kidney by : Yingyu Huang

Download or read book Surface Charge-mediated Interactions and Transport of Ultrasmall Gold Nanoparticles in the Normal and Diseased Kidney written by Yingyu Huang and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamental understanding of the interactions and transport of nanoparticles in the normal and diseased kidney will provide a foundation for engineering the next generation of renal nanomedicine. Meanwhile, it can also provide insights to the renal physiology and the pathophysiology of renal diseases. To gain such a fundamental understanding requires us to correlate the physicochemical properties of nanoparticles with their interactions and transport in different renal segments at the tissue and the cellular levels. While the size-dependent intrarenal interaction and transport of nanoparticles has been well demonstrated over the past decades, how surface charge of nanoparticles can impact their interaction and transport in different renal segments remains less understood. This dissertation aims to unravel the surface charge-mediated interactions and transport of nanoparticles in the normal and diseased kidney. Chapter 1 of this dissertation reviews the current understanding of the interactions and transport of nanoparticles in different renal segments as well as the pathophysiology of different renal diseases associated to different renal segments. Chapter 2 describes the surface charge-mediated nano-bio interactions of ultrasmall gold nanoparticles in the normal kidneys at the tissue and the cellular levels in relation to the surface charge species and the spatial configuration of the terminal charge groups. Chapter 3 emphasizes on the correlation between the in vivo transport profiles and the intrarenal interactions of renal-clearable gold nanoparticles with different surface charge in both the normal and diseased kidney. Lastly, chapter 4 presents the summary and outlook. In this dissertation, we provide a clear picture of the surface charge-mediated interactions and transport of ultrasmall gold nanoparticles in the normal and diseased kidney at the tissue and the cellular levels. We believe this work can contribute to the design of renal nanomedicine for the diagnosis and treatment of kidney diseases and advance our fundamental understanding of the renal physiology and the pathophysiology of renal diseases.

Fluorescently Labeled Gold Nanoparticles

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Publisher :
ISBN 13 :
Total Pages : 233 pages
Book Rating : 4.:/5 (113 download)

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Book Synopsis Fluorescently Labeled Gold Nanoparticles by : Ana Milošević

Download or read book Fluorescently Labeled Gold Nanoparticles written by Ana Milošević and published by . This book was released on 2018 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Gold Nanoparticles in Biomedical Applications

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Publisher : CRC Press
ISBN 13 : 1351360485
Total Pages : 332 pages
Book Rating : 4.3/5 (513 download)

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Book Synopsis Gold Nanoparticles in Biomedical Applications by : Lev Dykman

Download or read book Gold Nanoparticles in Biomedical Applications written by Lev Dykman and published by CRC Press. This book was released on 2017-12-12 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses fabrication of functionalized gold nanoparticles (GNPs) and multifunctional nanocomposites, their optical properties, and applications in biological studies. This is the very first book of its kind to comprehensively discuss published data on in vitro and in vivo biodistribution, toxicity, and uptake of GNP by mammalian cells providing a systematization of data over the GNP types and parameters, their surface functionalization, animal and cell models. As distinct from other related books, Gold Nanoparticles in Biomedical Applications discusses the immunological properties of GNPs and summarizes their applications as an antigen carrier and adjuvant in immunization for the preparation of antibodies in vivo. Although the potential of GNPs in nanobiotechnology has been recognized for the past decade, new insights into the unique properties of multifunctional nanostructures have recently emerged. With these developments in mind, this book unites ground breaking experimental data with a discussion of hybrid nanoparticle systems that combine different nanomaterials to create multifunctional structures. These novel hybrids constitute the material basis of theranostics, bringing together the advanced properties of functionalized GNPs and composites into a single multifunctional nanostructure with simultaneous diagnostic and therapeutic functions. Such nanohybrids can be physically and chemically tailored for a particular organ, disease, and patient thus making personalized medicine available.

Protein-Nanoparticle Interactions

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Publisher : Springer Science & Business Media
ISBN 13 : 3642375553
Total Pages : 95 pages
Book Rating : 4.6/5 (423 download)

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Book Synopsis Protein-Nanoparticle Interactions by : Masoud Rahman

Download or read book Protein-Nanoparticle Interactions written by Masoud Rahman and published by Springer Science & Business Media. This book was released on 2013-06-24 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, the fabrication of nanomaterials and exploration of their properties have attracted the attention of various scientific disciplines such as biology, physics, chemistry, and engineering. Although nanoparticulate systems are of significant interest in various scientific and technological areas, there is little known about the safety of these nanoscale objects. It has now been established that the surfaces of nanoparticles are immediately covered by biomolecules (e.g. proteins, ions, and enzymes) upon their entrance into a biological medium. This interaction with the biological medium modulates the surface of the nanoparticles, conferring a “biological identity” to their surfaces (referred to as a “corona”), which determines the subsequent cellular/tissue responses. The new interface between the nanoparticles and the biological medium/proteins, called “bio-nano interface,” has been very rarely studied in detail to date, though the interest in this topic is rapidly growing. In this book, the importance of the physiochemical characteristics of nanoparticles for the properties of the protein corona is discussed in detail, followed by comprehensive descriptions of the methods for assessing the protein-nanoparticle interactions. The advantages and limitations of available corona evaluation methods (e.g. spectroscopy methods, mass spectrometry, nuclear magnetic resonance, electron microscopy, X-ray crystallography, and differential centrifugal sedimentation) are examined in detail, followed by a discussion of the possibilities for enhancing the current methods and a call for new techniques. Moreover, the advantages and disadvantages of protein-nanoparticle interaction phenomena are explored and discussed, with a focus on the biological impacts.

Interactions of Gold Nanoparticles with Polymeric Membranes

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (92 download)

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Book Synopsis Interactions of Gold Nanoparticles with Polymeric Membranes by : Amelie Helena Ruth Koch

Download or read book Interactions of Gold Nanoparticles with Polymeric Membranes written by Amelie Helena Ruth Koch and published by . This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Gold Nanoparticles For Physics, Chemistry And Biology (Second Edition)

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Publisher : World Scientific
ISBN 13 : 1786341263
Total Pages : 681 pages
Book Rating : 4.7/5 (863 download)

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Book Synopsis Gold Nanoparticles For Physics, Chemistry And Biology (Second Edition) by : Catherine Louis

Download or read book Gold Nanoparticles For Physics, Chemistry And Biology (Second Edition) written by Catherine Louis and published by World Scientific. This book was released on 2017-06-02 with total page 681 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gold Nanoparticles for Physics, Chemistry and Biology offers an overview of recent research into gold nanoparticles, covering their discovery, usage and contemporary practical applications.This Second Edition begins with a history of over 2000 years of the use of gold nanoparticles, with a review of the specific properties which make gold unique. Updated chapters include gold nanoparticle preparation methods, their plasmon resonance and thermo-optical properties, their catalytic properties and their future technological applications. New chapters have been included, and reveal the growing impact of plasmonics in research, with an introduction to quantum plasmonics, plasmon assisted catalysis and electro-photon conversion. The growing field of nanoparticles for health is also addressed with a study of gold nanoparticles as radiosensibiliser for radiotherapy, and of gold nanoparticle functionalisation. This new edition also considers the relevance of bimetallic nanoparticles for specific applications.World-class scientists provide the most up-to-date findings for an introduction to gold nanoparticles within the related areas of chemistry, biology, material science, optics and physics. It is perfectly suited to advanced level students and researchers looking to enhance their knowledge in the study of gold nanoparticles.

Gold Nanoparticle-lipid Bilayer Interactions

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (63 download)

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Book Synopsis Gold Nanoparticle-lipid Bilayer Interactions by : Thomas Derrien

Download or read book Gold Nanoparticle-lipid Bilayer Interactions written by Thomas Derrien and published by . This book was released on 2009 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Microbial Interactions at Nanobiotechnology Interfaces

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Publisher : John Wiley & Sons
ISBN 13 : 1119617197
Total Pages : 420 pages
Book Rating : 4.1/5 (196 download)

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Book Synopsis Microbial Interactions at Nanobiotechnology Interfaces by : R. Navanietha Krishnaraj

Download or read book Microbial Interactions at Nanobiotechnology Interfaces written by R. Navanietha Krishnaraj and published by John Wiley & Sons. This book was released on 2021-11-02 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: MICROBIAL INTERACTIONS AT NANOBIOTECHNOLOGY INTERFACES This book covers a wide range of topics including synthesis of nanomaterials with specific size, shape, and properties, structure-function relationships, tailoring the surface of nanomaterials for improving the properties, interaction of nanomaterials with proteins/microorganism/eukaryotic cells, and applications in different sectors. This book also provides a strong foundation for researchers who are interested to venture into developing functionalized nanomaterials for any biological applications in their research. Practical concepts such as modelling nanomaterials, and simulating the molecular interactions with biomolecules, transcriptomic or genomic approaches, advanced imaging techniques to investigate the functionalization of nanomaterials/interaction of nanomaterials with biomolecules and microorganisms are some of the chapters that offer significant benefits to the researchers.