Integrative Pharmacology

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Integrative Pharmacology-based Research on Traditional Medicine: Methodologies, Medical and Pharmacological Applications

Author : Hai Yu Xu
Publisher : Frontiers Media SA
ISBN 13 : 2832535518
Total Pages : 1019 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Integrative Pharmacology-based Research on Traditional Medicine: Methodologies, Medical and Pharmacological Applications by : Hai Yu Xu

Download or read book Integrative Pharmacology-based Research on Traditional Medicine: Methodologies, Medical and Pharmacological Applications written by Hai Yu Xu and published by Frontiers Media SA. This book was released on 2023-09-19 with total page 1019 pages. Available in PDF, EPUB and Kindle. Book excerpt: ntegrative Pharmacology can be used to determine the multi-pharmacological effects of traditional medicines such as traditional Chinese medicine (TCM), Kampo, Sa-sang, Ayurveda, etc.). Through qualitative and quantitative pharmacokinetic-pharmacodynamic (PK-PD) correlations among multi-constituents and multi-targets, integrating chemical profiling, ADME/PK processes, molecular network calculation and resulting experimental validation, the use of Integrative Pharmacology has become widespread. The data has provided a novel paradigm to evaluate the druggability of bioactive ingredients of herbs or formulae, to decipher the pharmacological mechanisms of drug action and to screen potentially new indications for approved drugs and previously unidentified adverse events. On this basis, Integrative Pharmacology may offer an effective way to test the potential scientific basis for traditional medicines and to assess what roles of traditional medicine can and cannot play in pharmaceuticals.

Integrative Pharmacology

Author : Greg Sperber
Publisher :
ISBN 13 : 9781891845697
Total Pages : 479 pages
Book Rating : 4.8/5 (456 download)

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Book Synopsis Integrative Pharmacology by : Greg Sperber

Download or read book Integrative Pharmacology written by Greg Sperber and published by . This book was released on 2016 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Integrated Pharmacology

Author : Greg Sperber
Publisher : Blue Poppy Enterprises, Inc.
ISBN 13 : 9781891845413
Total Pages : 472 pages
Book Rating : 4.8/5 (454 download)

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Book Synopsis Integrated Pharmacology by : Greg Sperber

Download or read book Integrated Pharmacology written by Greg Sperber and published by Blue Poppy Enterprises, Inc.. This book was released on 2007 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: Integrated Pharmacology: Combining Modern Pharmacology with Chinese Medicine, by Dr Greg Sperber, gives you basic information about each common class of Western pharmaceuticals. For each category of drug, Dr Sperber gives us the generic names, pronunciation, and registered proprietary versions, an explanation of function, mechanism of action, dosages for adults, children, and the elderly, possible adverse affects, red flags, and the most up-to-the-minute information on specific drug-drug and drug-herb interactions that may affect your patients. Additionally, the book includes commentary by Bob Flaws on a three-part system for evaluating Western meds using Chinese medical principles and a Chinese medical analysis of each class of drugs using this three-part system. This book has Over 130 illustrations showing the functions and mechanisms of each type of drug as well as a page-by-page glossary of potentially difficult terms throughout the book.

Quantitative Pharmacology

Author : Johan Gabrielsson
Publisher : Swedish Pharmaceutical Press
ISBN 13 : 9781466560314
Total Pages : 0 pages
Book Rating : 4.5/5 (63 download)

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Book Synopsis Quantitative Pharmacology by : Johan Gabrielsson

Download or read book Quantitative Pharmacology written by Johan Gabrielsson and published by Swedish Pharmaceutical Press. This book was released on 2012-05-07 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: PKPD awareness is vital if we are to attempt to relate preclinical results to the acute and long term consequences in humans. The debate on whether preclinical findings can be translated to the human usage is still engaging scientists across industry, academia and regulatory bodies. Pharmacokinetics (PK) and pharmacodynamics (PD) comprise traditionally distinct disciplines within pharmacology, the study of the interaction of drugs with the body. It is our intention to show that by deliberately, intimately and systematically integrate these disciplines our understanding of drugs and the efficiency and effectiveness of drug discovery and development may be greatly enhanced. The book is therefore written with a broad audience in mind and focuses on concepts. Pharmacologists of all sorts, safety scientists, pharmacokineticists, medicinal chemists, clinicians, statisticians, veterinarians, animal science professionals, project leaders and students of medical, pharmaceutical and veterinary sciences are the primary targets. This textbook Introduces the basics of PK and PD concepts Outlines the implications of integrating PK and PD analysis Introduces the principles behind different biomarkers and inter-species scaling Discusses experimental design of PK, PD and safety studies in non-human species Covers numerous real life Case Studies from the drug discovery arena

Integrative Nursing

Author : Andrew Weil
Publisher : Oxford University Press, USA
ISBN 13 : 019085104X
Total Pages : 745 pages
Book Rating : 4.1/5 (98 download)

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Book Synopsis Integrative Nursing by : Andrew Weil

Download or read book Integrative Nursing written by Andrew Weil and published by Oxford University Press, USA. This book was released on 2018-11-27 with total page 745 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of "Integrative Nursing" is a complete roadmap to integrative patient care, providing a guide to the whole person/whole systems assessment and clinical interventions for individuals, families, and communities. Treatment strategies described in this version employ the full complement of evidence-informed methodologies in a tailored, person-centered approach to care. Integrative medicine is defined as healing-oriented medicine that takes account of the whole person (body, mind, and spirit) as well as all aspects of the lifestyle; it emphasizes the therapeutic relationship and makes use of appropriate therapies, but conventional and alternative. -- From publisher's description

Polypharmacology

Author : Zhiguo Wang
Publisher : Springer Nature
ISBN 13 : 3031049985
Total Pages : 870 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Polypharmacology by : Zhiguo Wang

Download or read book Polypharmacology written by Zhiguo Wang and published by Springer Nature. This book was released on 2022-08-01 with total page 870 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is a growing interest in unmet needs for the development of a new discipline in drug discovery and in university education on polypharmacology. However, there has not been a book with the comprehensive compilation of basic knowledge and advanced methodology that is needed. This book aims to meet the needs making Polypharmacology a new sub-discipline of Pharmacology, not only being a hot area of pharmacological research and education but also a new paradigm for drug discovery. It contains the contents covering the entire scope of Polypharmacology including systemic in-depth exposition of basic knowledge, novel concepts, innovative technologies, and translational and clinical applications by showcasing state-of-the-art strategies and step-by-step instructions of cutting-edge methods. The contents of this book targets broad readerships including scientists in pharmacology research and drug development, and university teachers and graduates in medical school or school of pharmacy.

Regenerative Pharmacology

Author : George J. Christ
Publisher : Cambridge University Press
ISBN 13 : 1107354730
Total Pages : 361 pages
Book Rating : 4.1/5 (73 download)

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Book Synopsis Regenerative Pharmacology by : George J. Christ

Download or read book Regenerative Pharmacology written by George J. Christ and published by Cambridge University Press. This book was released on 2013-04-15 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regenerative medicine is broadly defined as the repair or replacement of damaged cells, tissues and organs. It is a multidisciplinary effort in which technologies derive from the fields of cell, developmental and molecular biology; chemical and material sciences (i.e. nanotechnology); engineering; surgery; transplantation; immunology; molecular genetics; physiology; and pharmacology. As regenerative medicine technologies continue to evolve and expand across the boundaries of numerous scientific disciplines, they remain at the forefront of the translational research frontier with the potential to radically alter the treatment of a wide variety of disease and dysfunction. This book will draw attention to the critical role that pharmacological sciences will undeniably play in the advancement of these treatments. This book is invaluable for advanced students, postdoctoral fellows, researchers new to the field of regenerative medicine/tissue engineering, and experienced investigators looking for new research avenues. The first state-of-the-art book in this rapidly evolving field of research.

Quantitative Pharmacology

Author : Johan Gabrielsson
Publisher :
ISBN 13 : 9789197945233
Total Pages : 263 pages
Book Rating : 4.9/5 (452 download)

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Book Synopsis Quantitative Pharmacology by : Johan Gabrielsson

Download or read book Quantitative Pharmacology written by Johan Gabrielsson and published by . This book was released on 2012 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Regenerative Pharmacology

Author : George J. Christ
Publisher : Cambridge University Press
ISBN 13 : 0521899494
Total Pages : 361 pages
Book Rating : 4.5/5 (218 download)

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Book Synopsis Regenerative Pharmacology by : George J. Christ

Download or read book Regenerative Pharmacology written by George J. Christ and published by Cambridge University Press. This book was released on 2013-04-15 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: A state-of-the-art primer on the role of pharmacological sciences in regenerative medicine, for advanced students, postdoctoral fellows, and researchers.

Drug Repositioning: Current Advances and Future Perspectives

Author : Yuhei Nishimura
Publisher : Frontiers Media SA
ISBN 13 : 288945696X
Total Pages : 153 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Drug Repositioning: Current Advances and Future Perspectives by : Yuhei Nishimura

Download or read book Drug Repositioning: Current Advances and Future Perspectives written by Yuhei Nishimura and published by Frontiers Media SA. This book was released on 2019-01-11 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug repositioning is the process of identifying new indications for existing drugs. At present, the conventional de novo drug discovery process requires an average of about 14 years and US$2.5 billion to approve and launch a drug. Drug repositioning can reduce the time and cost of this process because it takes advantage of drugs already in clinical use for other indications or drugs that have cleared phase I safety trials but have failed to show efficacy in the intended diseases. Historically, drug repositioning has been realized through serendipitous clinical observations or improved understanding of disease mechanisms. However, recent technological advances have enabled a more systematic approach to drug repositioning. This eBook collects 16 articles from 112 authors, providing readers with current advances and future perspectives of drug repositioning.

Multidisciplinary Applications of Natural Science for Drug Discovery and Integrative Medicine

Author : Aslam, Muhammad Shahzad
Publisher : IGI Global
ISBN 13 : 1668494647
Total Pages : 418 pages
Book Rating : 4.6/5 (684 download)

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Book Synopsis Multidisciplinary Applications of Natural Science for Drug Discovery and Integrative Medicine by : Aslam, Muhammad Shahzad

Download or read book Multidisciplinary Applications of Natural Science for Drug Discovery and Integrative Medicine written by Aslam, Muhammad Shahzad and published by IGI Global. This book was released on 2023-07-10 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: The multidisciplinary applications of natural science in drug discovery are essential for identifying and developing new drugs and represent a promising area of research. Drug discovery is a complex and challenging process that involves multiple disciplines, including biology, chemistry, pharmacology, and medicine. One of the most interesting areas of drug discovery is using natural science, which involves the study of natural products and their potential therapeutic benefits, in which the research literature has previously been lacking appropriate attention. Multidisciplinary Applications of Natural Science for Drug Discovery and Integrative Medicine is a research book that bridges the gap between traditional and natural science approaches to identify new drug molecules in treating various diseases. The book focuses on allopathic and complementary medicine. It takes a cross-disciplinary examination of biology, chemistry, pharmacology, mathematics, physics, and medicine. This book is suitable for researchers, post-doctoral fellows, graduate students, and post-graduate students interested in exploring natural science's multidisciplinary applications in drug discovery and integrative medicine.

Drug Discovery Toxicology

Author : Yvonne Will
Publisher : John Wiley & Sons
ISBN 13 : 1119053390
Total Pages : 899 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis Drug Discovery Toxicology by : Yvonne Will

Download or read book Drug Discovery Toxicology written by Yvonne Will and published by John Wiley & Sons. This book was released on 2016-03-22 with total page 899 pages. Available in PDF, EPUB and Kindle. Book excerpt: As a guide for pharmaceutical professionals to the issues and practices of drug discovery toxicology, this book integrates and reviews the strategy and application of tools and methods at each step of the drug discovery process. • Guides researchers as to what drug safety experiments are both practical and useful • Covers a variety of key topics – safety lead optimization, in vitro-in vivo translation, organ toxicology, ADME, animal models, biomarkers, and –omics tools • Describes what experiments are possible and useful and offers a view into the future, indicating key areas to watch for new predictive methods • Features contributions from firsthand industry experience, giving readers insight into the strategy and execution of predictive toxicology practices

Issues in Pharmacology, Pharmacy, Drug Research, and Drug Innovation: 2012 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1481645625
Total Pages : 619 pages
Book Rating : 4.4/5 (816 download)

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Book Synopsis Issues in Pharmacology, Pharmacy, Drug Research, and Drug Innovation: 2012 Edition by :

Download or read book Issues in Pharmacology, Pharmacy, Drug Research, and Drug Innovation: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2013-01-10 with total page 619 pages. Available in PDF, EPUB and Kindle. Book excerpt: Issues in Pharmacology, Pharmacy, Drug Research, and Drug Innovation: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Molecular Pharmacology. The editors have built Issues in Pharmacology, Pharmacy, Drug Research, and Drug Innovation: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Molecular Pharmacology in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Pharmacology, Pharmacy, Drug Research, and Drug Innovation: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

A Pharmacology Primer

Author : Terry Kenakin
Publisher : Academic Press
ISBN 13 : 0128139587
Total Pages : 488 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis A Pharmacology Primer by : Terry Kenakin

Download or read book A Pharmacology Primer written by Terry Kenakin and published by Academic Press. This book was released on 2018-10-26 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, Fifth Edition features the latest ideas and research regarding the application of pharmacology to the process of drug discovery. Written by well-respected pharmacologist, Terry P. Kenakin, this primer is an indispensable resource for all those involved in drug discovery. This updated edition has been thoroughly revised to include material on quantifying drug efficacy through bias and cluster analysis, the impact of molecular dynamics and protein structural analysis, the real time kinetic analysis of drug effect, virtual screening for new drug chemical scaffolds, and much more. With full color illustrations and new examples throughout, this book remains a top reference for all industry and academic scientists that is also ideal for students directly involved in drug discovery or pharmacologic research. Highlights changes surrounding strategies for drug discovery, providing a comprehensive reference and featuring advances in the methods involved Includes multiple new sections, such as development and utilization of models in pharmacology, de-orphanization of new drug targets, predicting impact of disease on drug pharmacokinetics, and the impact of enzyme kinetics on drug-drug interactions Illustrates the application of rapid inexpensive assays to predict activity in the therapeutic setting, showing data outcomes and the limitations inherent in interpreting this data

Integrated Pharmacology

Author :
Publisher :
ISBN 13 :
Total Pages : 675 pages
Book Rating : 4.:/5 (821 download)

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Book Synopsis Integrated Pharmacology by :

Download or read book Integrated Pharmacology written by and published by . This book was released on 2006 with total page 675 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Graduate Programs in the Biological/Biomedical Sciences & Health-Related Medical Professions 2014 (Grad 3)

Author : Peterson's
Publisher : Peterson's
ISBN 13 : 0768938600
Total Pages : 4553 pages
Book Rating : 4.7/5 (689 download)

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Book Synopsis Graduate Programs in the Biological/Biomedical Sciences & Health-Related Medical Professions 2014 (Grad 3) by : Peterson's

Download or read book Graduate Programs in the Biological/Biomedical Sciences & Health-Related Medical Professions 2014 (Grad 3) written by Peterson's and published by Peterson's. This book was released on 2013-12-20 with total page 4553 pages. Available in PDF, EPUB and Kindle. Book excerpt: Peterson's Graduate Programs in the Biological/Biomedical Sciences & Health-Related Medical Professions 2014 contains comprehensive profiles of nearly 6,800 graduate programs in disciplines such as, allied health, biological & biomedical sciences, biophysics, cell, molecular, & structural biology, microbiological sciences, neuroscience & neurobiology, nursing, pharmacy & pharmaceutical sciences, physiology, public health, and more. Up-to-date data, collected through Peterson's Annual Survey of Graduate and Professional Institutions, provides valuable information on degree offerings, professional accreditation, jointly offered degrees, part-time and evening/weekend programs, postbaccalaureate distance degrees, faculty, students, requirements, expenses, financial support, faculty research, and unit head and application contact information. There are helpful links to in-depth descriptions about a specific graduate program or department, faculty members and their research, and more. There are also valuable articles on financial assistance, the graduate admissions process, advice for international and minority students, and facts about accreditation, with a current list of accrediting agencies.

Antitargets and Drug Safety

Author : Laszlo Urban
Publisher : John Wiley & Sons
ISBN 13 : 3527673660
Total Pages : 524 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Antitargets and Drug Safety by : Laszlo Urban

Download or read book Antitargets and Drug Safety written by Laszlo Urban and published by John Wiley & Sons. This book was released on 2015-02-23 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: With its focus on emerging concerns of kinase and GPCR-mediated antitarget effects, this vital reference for drug developers addresses one of the hot topics in drug safety now and in future. Divided into three major parts, the first section deals with novel technologies and includes the utility of adverse event reports to drug discovery, the translational aspects of preclinical safety findings, broader computational prediction of drug side-effects, and a description of the serotonergic system. The main part of the book looks at some of the most common antitarget-mediated side effects, focusing on hepatotoxicity in drug safety, cardiovascular toxicity and signaling effects via kinase and GPCR anti-targets. In the final section, several case studies of recently developed drugs illustrate how to prevent anti-target effects and how big pharma deals with them if they occur. The more recent field of systems pharmacology has gained prominence and this is reflected in chapters dedicated to the utility in deciphering and modeling anti-targets. The final chapter is concerned with those compounds that inadvertently elicit CNS mediated adverse events, including a pragmatic description of ways to mitigate these types of safety risks. Written as a companion to the successful book on antitargets by Vaz and Klabunde, this new volume focuses on recent progress and new classes, methods and case studies that were not previously covered.