Progress Toward Transforming the Integrated Risk Information System (IRIS) Program

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Publisher : National Academies Press
ISBN 13 : 0309474949
Total Pages : 130 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Progress Toward Transforming the Integrated Risk Information System (IRIS) Program by : National Academies of Sciences, Engineering, and Medicine

Download or read book Progress Toward Transforming the Integrated Risk Information System (IRIS) Program written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2018-04-11 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past several years, the US Environmental Protection Agency (EPA) has been transforming the procedures of its Integrated Risk Information System (IRIS), a program that produces hazard and doseâ€'response assessments of environmental chemicals and derives toxicity values that can be used to estimate risks posed by exposures to them. The transformation was initiated after suggestions for program reforms were provided in a 2011 report from the National Academies of Sciences, Engineering, and Medicine that reviewed a draft IRIS assessment of formaldehyde. In 2014, the National Academies released a report that reviewed the IRIS program and evaluated the changes implemented in it since the 2011 report. Since 2014, new leadership of EPA's National Center for Environmental Assessment (NCEA) and IRIS program has instituted even more substantive changes in the IRIS program in response to the recommendations in the 2014 report. Progress Toward Transforming the Integrated Risk Information System Program: A 2018 Evaluation reviews the EPA's progress toward addressing the past recommendations from the National Academies.

Critical Aspects of EPA's IRIS Assessment of Inorganic Arsenic

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Publisher : National Academies Press
ISBN 13 : 0309297095
Total Pages : 128 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Critical Aspects of EPA's IRIS Assessment of Inorganic Arsenic by : National Research Council

Download or read book Critical Aspects of EPA's IRIS Assessment of Inorganic Arsenic written by National Research Council and published by National Academies Press. This book was released on 2013-11-20 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: The US Environmental Protection Agency (EPA) Integrated Risk Information System (IRIS) program develops toxicologic assessments of environmental contaminants. IRIS assessments provide hazard identification and dose-response assessment information. The information is then used in conjunction with exposure information to characterize risks to public health and may be used in risk-based decisionmaking, in regulatory actions, and for other risk-management purposes. Since the middle 1990s, EPA has been in the process of updating the IRIS assessment of inorganic arsenic. In response to a congressional mandate for an independent review of the IRIS assessment of inorganic arsenic, EPA requested that the National Research Council convene a committee to conduct a two-phase study. Critical Aspects of EPA's IRIS Assessment of Inorganic Arsenic is the report of the first phase of that study. This report evaluates critical scientific issues in assessing cancer and noncancer effects of oral exposure to inorganic arsenic and offers recommendations on how the issues could be addressed in EPA's IRIS assessment.

Phthalates and Cumulative Risk Assessment

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Publisher : National Academies Press
ISBN 13 : 0309128412
Total Pages : 208 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Phthalates and Cumulative Risk Assessment by : National Research Council

Download or read book Phthalates and Cumulative Risk Assessment written by National Research Council and published by National Academies Press. This book was released on 2009-01-19 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: People are exposed to a variety of chemicals throughout their daily lives. To protect public health, regulators use risk assessments to examine the effects of chemical exposures. This book provides guidance for assessing the risk of phthalates, chemicals found in many consumer products that have been shown to affect the development of the male reproductive system of laboratory animals. Because people are exposed to multiple phthalates and other chemicals that affect male reproductive development, a cumulative risk assessment should be conducted that evaluates the combined effects of exposure to all these chemicals. The book suggests an approach for cumulative risk assessment that can serve as a model for evaluating the health risks of other types of chemicals.

Environmental Decisions in the Face of Uncertainty

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Publisher : National Academies Press
ISBN 13 : 0309290236
Total Pages : 280 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Environmental Decisions in the Face of Uncertainty by : Institute of Medicine

Download or read book Environmental Decisions in the Face of Uncertainty written by Institute of Medicine and published by National Academies Press. This book was released on 2013-05-20 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: The U.S. Environmental Protection Agency (EPA) is one of several federal agencies responsible for protecting Americans against significant risks to human health and the environment. As part of that mission, EPA estimates the nature, magnitude, and likelihood of risks to human health and the environment; identifies the potential regulatory actions that will mitigate those risks and protect public health1 and the environment; and uses that information to decide on appropriate regulatory action. Uncertainties, both qualitative and quantitative, in the data and analyses on which these decisions are based enter into the process at each step. As a result, the informed identification and use of the uncertainties inherent in the process is an essential feature of environmental decision making. EPA requested that the Institute of Medicine (IOM) convene a committee to provide guidance to its decision makers and their partners in states and localities on approaches to managing risk in different contexts when uncertainty is present. It also sought guidance on how information on uncertainty should be presented to help risk managers make sound decisions and to increase transparency in its communications with the public about those decisions. Given that its charge is not limited to human health risk assessment and includes broad questions about managing risks and decision making, in this report the committee examines the analysis of uncertainty in those other areas in addition to human health risks. Environmental Decisions in the Face of Uncertainty explains the statement of task and summarizes the findings of the committee.

Science and Decisions

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Publisher : National Academies Press
ISBN 13 : 0309120462
Total Pages : 422 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Science and Decisions by : National Research Council

Download or read book Science and Decisions written by National Research Council and published by National Academies Press. This book was released on 2009-03-24 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Risk assessment has become a dominant public policy tool for making choices, based on limited resources, to protect public health and the environment. It has been instrumental to the mission of the U.S. Environmental Protection Agency (EPA) as well as other federal agencies in evaluating public health concerns, informing regulatory and technological decisions, prioritizing research needs and funding, and in developing approaches for cost-benefit analysis. However, risk assessment is at a crossroads. Despite advances in the field, risk assessment faces a number of significant challenges including lengthy delays in making complex decisions; lack of data leading to significant uncertainty in risk assessments; and many chemicals in the marketplace that have not been evaluated and emerging agents requiring assessment. Science and Decisions makes practical scientific and technical recommendations to address these challenges. This book is a complement to the widely used 1983 National Academies book, Risk Assessment in the Federal Government (also known as the Red Book). The earlier book established a framework for the concepts and conduct of risk assessment that has been adopted by numerous expert committees, regulatory agencies, and public health institutions. The new book embeds these concepts within a broader framework for risk-based decision-making. Together, these are essential references for those working in the regulatory and public health fields.

Risks of Hazardous Wastes

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Author :
Publisher : William Andrew
ISBN 13 : 1437778437
Total Pages : 473 pages
Book Rating : 4.4/5 (377 download)

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Book Synopsis Risks of Hazardous Wastes by : Paul E. Rosenfeld

Download or read book Risks of Hazardous Wastes written by Paul E. Rosenfeld and published by William Andrew. This book was released on 2011-03-22 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hazardous waste in the environment is one of the most difficult challenges facing our society. The purpose of this book is to provide a background of the many aspects of hazardous waste, from its sources to its consequences, focusing on the risks posed to human health and the environment. It explains the legislation and regulations surrounding hazardous waste; however, the scope of the book is much broader, discussing agents that are released into the environment that might not be classified as hazardous waste under the regulatory system, but nonetheless pose substantial hazards to human health and the environment. It provides a background of some of the major generators of hazardous wastes, explains the pathways by which humans and wildlife are exposed, and includes discussion of the adverse health effects linked to these pollutants. It provides numerous case studies of hazardous waste mismanagement that have led to disastrous consequences, and highlights the deficiencies in science and regulation that have allowed the public to be subjected to myriad potentially hazardous agents. Finally, it provides a discussion of measures that will need to be taken to control society's hazardous waste problem. This book was designed to appeal to a wide range of audiences, including students, professionals, and general readers interested in the topic. - Provides information about sources of and health risks posed by hazardous waste - Explains the legislation and regulations surrounding hazardous waste - Includes numerous case studies of mismanagement, highlights deficiencies in science and regulation and discusses measures to tackle society's hazardous waste problems

The Use of Systematic Review in Epa's Toxic Substances Control ACT Risk Evaluations

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Publisher : National Academies Press
ISBN 13 : 9780309683869
Total Pages : pages
Book Rating : 4.6/5 (838 download)

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Book Synopsis The Use of Systematic Review in Epa's Toxic Substances Control ACT Risk Evaluations by : National Academies Of Sciences Engineeri

Download or read book The Use of Systematic Review in Epa's Toxic Substances Control ACT Risk Evaluations written by National Academies Of Sciences Engineeri and published by National Academies Press. This book was released on 2021-11-16 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Systematic review - a scientific investigation that focuses on a specific question and uses explicit, prespecified scientific methods to identify, select, assess, and summarize the findings of similar but separate studies - has become the foundation for assessing evidence to be used for decision making in a variety of health contexts, including health care and public health. At the request of the Environmental Protection Agency (EPA), this publication reviews EPA's 2018 guidance document Application of Systematic Review in TSCA (Toxic Substances and Control Act) Risk Evaluations and associated materials to determine whether the process is comprehensive, workable, objective, and transparent.

Toxicological Profile for Isophorone

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Publisher :
ISBN 13 :
Total Pages : 120 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Toxicological Profile for Isophorone by :

Download or read book Toxicological Profile for Isophorone written by and published by . This book was released on 1989 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Essentials of Toxicology for Health Protection

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Publisher : Oxford University Press
ISBN 13 : 9780199652549
Total Pages : 368 pages
Book Rating : 4.6/5 (525 download)

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Book Synopsis Essentials of Toxicology for Health Protection by : David Baker

Download or read book Essentials of Toxicology for Health Protection written by David Baker and published by Oxford University Press. This book was released on 2012-03-15 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essentials of Toxicology for Health Protection is a key handbook and course reader for all health protection professionals. It covers the basics of toxicology and its application to issues of topical concern including contaminated land, water pollution and traditional medicines.

Health Effects Assessment Summary Tables

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Publisher :
ISBN 13 :
Total Pages : 414 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Health Effects Assessment Summary Tables by :

Download or read book Health Effects Assessment Summary Tables written by and published by . This book was released on 1997 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Science for Environmental Protection

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Publisher : National Academies Press
ISBN 13 : 0309264898
Total Pages : 188 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Science for Environmental Protection by : National Research Council

Download or read book Science for Environmental Protection written by National Research Council and published by National Academies Press. This book was released on 2012-12-21 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: In anticipation of future environmental science and engineering challenges and technologic advances, EPA asked the National Research Council (NRC) to assess the overall capabilities of the agency to develop, obtain, and use the best available scientific and technologic information and tools to meet persistent, emerging, and future mission challenges and opportunities. Although the committee cannot predict with certainty what new environmental problems EPA will face in the next 10 years or more, it worked to identify some of the common drivers and common characteristics of problems that are likely to occur. Tensions inherent to the structure of EPA's work contribute to the current and persistent challenges faced by the agency, and meeting those challenges will require development of leading-edge scientific methods, tools, and technologies, and a more deliberate approach to systems thinking and interdisciplinary science. Science for Environmental Protection: The Road Ahead outlines a framework for building science for environmental protection in the 21st century and identified key areas where enhanced leadership and capacity can strengthen the agency's abilities to address current and emerging environmental challenges as well as take advantage of new tools and technologies to address them. The foundation of EPA science is strong, but the agency needs to continue to address numerous present and future challenges if it is to maintain its science leadership and meet its expanding mandates.

WHO guidelines on physical activity and sedentary behaviour

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Publisher : World Health Organization
ISBN 13 : 9240014888
Total Pages : 24 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis WHO guidelines on physical activity and sedentary behaviour by :

Download or read book WHO guidelines on physical activity and sedentary behaviour written by and published by World Health Organization. This book was released on 2020-11-20 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Review of EPA's Integrated Risk Information System (IRIS) Process

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Publisher : National Academies Press
ISBN 13 : 0309304172
Total Pages : 227 pages
Book Rating : 4.3/5 (93 download)

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Book Synopsis Review of EPA's Integrated Risk Information System (IRIS) Process by : National Research Council

Download or read book Review of EPA's Integrated Risk Information System (IRIS) Process written by National Research Council and published by National Academies Press. This book was released on 2014-06-25 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Integrated Risk Information System (IRIS) is a program within the US Environmental Protection Agency (EPA) that is responsible for developing toxicologic assessments of environmental contaminants. An IRIS assessment contains hazard identifications and dose-response assessments of various chemicals related to cancer and noncancer outcomes. Although the program was created to increase consistency among toxicologic assessments within the agency, federal, state, and international agencies and other organizations have come to rely on IRIS assessments for setting regulatory standards, establishing exposure guidelines, and estimating risks to exposed populations. Over the last decade, the National Research Council (NRC) has been asked to review some of the more complex and challenging IRIS assessments, including those of formaldehyde, dioxin, and tetrachloroethylene. In 2011, an NRC committee released its review of the IRIS formaldehyde assessment. Like other NRC committees that had reviewed IRIS assessments, the formaldehyde committee identified deficiencies in the specific assessment and more broadly in some of EPA's general approaches and specific methods. Although the committee focused on evaluating the IRIS formaldehyde assessment, it provided suggestions for improving the IRIS process and a roadmap for its revision in case EPA decided to move forward with changes to the process. Congress directed EPA to implement the report's recommendations and then asked the National Research Council to review the changes that EPA was making (or proposing to make) in response to the recommendations. Review of EPA's Integrated Risk Information System (IRIS) Process provides an overview of some general issues associated with IRIS assessments. This report then addresses evidence identification and evaluation for IRIS assessments and discusses evidence integration for hazard evaluation and methods for calculating reference values and unit risks. The report makes recommendations and considerations for future directions. Overall, Review of EPA's Integrated Risk Information System Process finds that substantial improvements in the IRIS process have been made, and it is clear that EPA has embraced and is acting on the recommendations in the NRC formaldehyde report. The recommendations of this report should be seen as building on the progress that EPA has already made.

Risk Assessment Guidance for Superfund: pt. A. Human health evaluation manual

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Author :
Publisher :
ISBN 13 :
Total Pages : 300 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Risk Assessment Guidance for Superfund: pt. A. Human health evaluation manual by :

Download or read book Risk Assessment Guidance for Superfund: pt. A. Human health evaluation manual written by and published by . This book was released on 1989 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Status of Reforms to EPA's Integrated Risk Information System

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Publisher :
ISBN 13 :
Total Pages : 140 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Status of Reforms to EPA's Integrated Risk Information System by : United States. Congress. House. Committee on Science, Space, and Technology (2011). Subcommittee on Oversight

Download or read book Status of Reforms to EPA's Integrated Risk Information System written by United States. Congress. House. Committee on Science, Space, and Technology (2011). Subcommittee on Oversight and published by . This book was released on 2014 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt:

A Compilation of Water Quality Goals

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (755 download)

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Book Synopsis A Compilation of Water Quality Goals by : Jon Bruce Marshack

Download or read book A Compilation of Water Quality Goals written by Jon Bruce Marshack and published by . This book was released on 2000 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

World Health Statistics 2019

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Publisher :
ISBN 13 : 9789241565707
Total Pages : 126 pages
Book Rating : 4.5/5 (657 download)

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Book Synopsis World Health Statistics 2019 by : World Health Organization

Download or read book World Health Statistics 2019 written by World Health Organization and published by . This book was released on 2019-06 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt: World Health Statistics 2019 summarizes recent trends and levels in life expectancy and causes of death, and reports on the health and health-related Sustainable Development Goals (SDGs) and associated targets. Where possible, the 2019 report disaggregates data by WHO region, World Bank income group, and sex; it also discusses differences in health status and access to preventive and curative services, particularly in relation to differences between men and women.