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Insulin Sensitivity In Postmenopausal Women
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Book Synopsis Hyperandrogenism in Women by : R. Pasquali
Download or read book Hyperandrogenism in Women written by R. Pasquali and published by Karger Medical and Scientific Publishers. This book was released on 2019-09-09 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hyperandrogenism profoundly affects women’s lives from lowering self-esteem to changing cognition and affective motivation. The polycystic ovary syndrome (PCOS) is the most common androgen excess disorder worldwide. While it is not the focus of this book, some aspects are discussed. The aim of this book is to improve understanding of androgen excess and its impact on several conditions. Topics include development of adipose tissue in females, insulin sensitivity, congenital adrenal hyperplasia, and Cushing’s disease/syndrome. There is also a discussion of PCOS with emphasis on in utero origins and specific genetic and epigenetic factors. This book provides a wealth of relevant information for every endocrinologist and gynecologist who wants to broaden their knowledge of androgens in various conditions.
Book Synopsis Insulin Sensitivity in Postmenopausal Women by : Anita Brenneman Derstine
Download or read book Insulin Sensitivity in Postmenopausal Women written by Anita Brenneman Derstine and published by . This book was released on 2000 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Polycystic Ovary Syndrome by : Andrea Dunaif
Download or read book Polycystic Ovary Syndrome written by Andrea Dunaif and published by Springer Science & Business Media. This book was released on 2008-01-12 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume includes the latest diagnostic criteria for PCOS and comprises the most up-to-date information about the genetic features and pathogenesis of PCOS. It critically reviews the methodological approaches and the evidence for various PCOS susceptibility genes. The book also discusses additional familial phenotypes of PCOS and their potential genetic basis. All four editors of this title are extremely prominent in the field of PCOS.
Book Synopsis Effect of Acute Resistance Exercise on Insulin Sensitivity in Untrained Postmenopausal Women by : Joel Chapman
Download or read book Effect of Acute Resistance Exercise on Insulin Sensitivity in Untrained Postmenopausal Women written by Joel Chapman and published by . This book was released on 2001 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Effects of Eccentric Ergometry on Insulin Sensitivity in Postmenopausal Women with Impaired Glucose Tolerance by : Laura C. Hill
Download or read book Effects of Eccentric Ergometry on Insulin Sensitivity in Postmenopausal Women with Impaired Glucose Tolerance written by Laura C. Hill and published by . This book was released on 2006 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Diabetes in Women by : Agathocles Tsatsoulis
Download or read book Diabetes in Women written by Agathocles Tsatsoulis and published by Springer Science & Business Media. This book was released on 2009-09-18 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gender differences impact the pathophysiology and clinical burden of diabetes in women. Exploring the complex interplay between gender and diabetes, Diabetes in Women provides a state-of-the-art update from conception to menopause and beyond. Written by experts in the field, Diabetes in Women covers sex differences in cardiometabolic risk, the impact of diabetes on women’s health, diabetes and pregnancy, offspring of the diabetic mother and the disease management of women with diabetes. Chapters include up to date information on cardiometabolic risk in women throughout the lifecycle and the differences between sexes in energy balance and body composition. Prominent authors also explore the impact of poverty and globalization on the emerging epidemic of obesity in developing countries. Designed for primary care and internal medicine physicians, endocrinologists, obstetricians and gynecologists, and trainees and basic scientists in these areas, Diabetes in Women is an invaluable resource and important contribution to the field.
Book Synopsis Research on the Menopause in the 1990s by :
Download or read book Research on the Menopause in the 1990s written by and published by . This book was released on 1996 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report reviews current research on the menopause, including studies on its symptons and their treatment, and its effects on the cardiovascular and skeletal systems. It also assesses the relevance of existing data to women in developing countries.
Book Synopsis Insulin Resistance and Cancer by : I. George Fantus
Download or read book Insulin Resistance and Cancer written by I. George Fantus and published by Springer Science & Business Media. This book was released on 2011-08-19 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the epidemiological associations between insulin resistance and cancer. This is followed by reviews of animal models which support this relationship and provide insight into potential mechanisms. Several chapters then provide detailed examination of the cellular and molecular changes characterizing the insulin resistant state, such as hyperinsulinemia, abnormal metabolism and hormone signaling, and how these interact with various tumor characteristics. For example some tumors present increased quantities of the fetal form of the insulin receptor, unique regulation of oxidative (Krebs’ cycle) metabolism (Warburg effect), as well as mutations in various relevant signaling pathways. Finally, the clinical implications of these data are integrated with considerations of insulin “sensitization” and potential metabolic interventions to prevent and treat cancer. It should be noted that while a number of cancers are associated with obesity the authors here have focused primarily on breast cancer as a key and significant model.
Book Synopsis Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity by : Franck Mauvais-Jarvis
Download or read book Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity written by Franck Mauvais-Jarvis and published by Springer. This book was released on 2017-12-08 with total page 630 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book provides a reference for years to come, written by world-renowned expert investigators studying sex differences, the role of sex hormones, the systems biology of sex, and the genetic contribution of sex chromosomes to metabolic homeostasis and diseases. In this volume, leaders of the pharmaceutical industry present their views on sex-specific drug discovery. Many of the authors presented at the Keystone Symposium on “Sex and gender factors affecting metabolic homeostasis, diabetes and obesity” to be held in March 2017 in Lake Tahoe, CA. This book will generate new knowledge and ideas on the importance of gender biology and medicine from a molecular standpoint to the population level and to provide the methods to study them. It is intended to be a catalyst leading to gender-specific treatments of metabolic diseases. There are fundamental aspects of metabolic homeostasis that are regulated differently in males and females, and influence both the development of diabetes and obesity and the response to pharmacological intervention. Still, most preclinical researchers avoid studying female rodents due to the added complexity of research plans. The consequence is a generation of data that risks being relevant to only half of the population. This is a timely moment to publish a book on sex differences in diseases as NIH leadership has asked scientists to consider sex as a biological variable in preclinical research, to ensure that women get the same benefit of medical research as men.
Book Synopsis Hormone Therapy and Replacement in Cancer and Aging-related Diseases by : Letícia Rangel
Download or read book Hormone Therapy and Replacement in Cancer and Aging-related Diseases written by Letícia Rangel and published by BoD – Books on Demand. This book was released on 2020-07-22 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited volume, Hormone Therapy and Replacement in Cancer and Aging-related Diseases, is a collection of reviewed and relevant research chapters, offering a comprehensive overview of recent developments in the field of hormone replacement therapy. The book comprises single chapters authored by various researchers and edited by experts active in the hormone replacement therapy research area. All chapters are complete in themselves but united under a common research study topic. This publication aims at providing a thorough overview of the latest research efforts by international authors on hormone replacement therapy, and opens new possible research paths for further novel developments.
Book Synopsis Vigorous Physical Activity, Heredity, and Modulation of Risk for Obesity and Type 2 Diabetes in Postmenopausal Women by : Jennifer Anne Wright
Download or read book Vigorous Physical Activity, Heredity, and Modulation of Risk for Obesity and Type 2 Diabetes in Postmenopausal Women written by Jennifer Anne Wright and published by . This book was released on 2007 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: The objective of this study was to determine whether insulin sensitivity could be altered by resistance training, and further if body composition or insulin sensitivity response to resistance training in postmenopausal women may be influenced by adrenergic receptor genetic variants and gene-gene interactions.
Book Synopsis Unravelling the Mechanisms of Menopause-induced Insulin Resistance: Novel Roles for Estradiol in Skeletal Muscle Mitochondrial Function by : Maria Jose Torres
Download or read book Unravelling the Mechanisms of Menopause-induced Insulin Resistance: Novel Roles for Estradiol in Skeletal Muscle Mitochondrial Function written by Maria Jose Torres and published by . This book was released on 2016 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt: Menopause results in a progressive decline in ovarian production of 17[beta]-estradiol (E2), increased adiposity and a higher risk for type-2 diabetes, but hormone replacement therapies containing E2 reverse most of these effects. However, we still lack a comprehensive understanding of the mechanism(s) by which E2 modulates insulin sensitivity (IS) and susceptibility to metabolic disease. By using a short-term ovariectomized mouse (surgical removal of ovaries, OVX) and pharmacological replacement of E2, here we have developed a model to study the short-term effects of menopause and E2 replacement therapies on mitochondrial function and IS, within a simplified context (i.e. in the absence of obesity). Given the primary role that skeletal muscle and liver play in glucose homeostasis, the aims of this work are two-fold. First, to determine whether decreased mitochondrial and cellular redox function represent the underlying molecular mechanisms for menopause-induced insulin resistance, and how E2 replacement can reverse these effects. Second, to determine the effects of ovarian E2 depletion and replacement on liver mitochondrial and redox functions, with a specific emphasis on NADH:ubiquinone oxidoreductase (mitochondrial complex I) kinetics and its associated H2O2 emitting potential. The studies herein provide evidence that E2 protects mitochondrial function and redox homeostasis in skeletal muscle by increasing complex I and IIII activities, enhancing electron transfer supercomplex assembly, preventing free radical leak, and decreasing lipid packing of mitochondrial membranes. We report, for the first time, the detection of E2 in skeletal muscle mitochondria, thus providing compelling evidence that E2 localizes to mitochondrial membranes and regulates mitochondrial function through the "fine-tuning" of electron transfer efficiency. Finally, while OVX by itself did not induce major changes on mitochondrial function in the liver (at least in a short-term OVX model), E2 treatment had detrimental effects on mitochondrial function, particularly targeted to complex I. This highlights the remarkably opposite effects E2 can exert on such critical organelles as the mitochondria across tissues with a different "bioenergetics signature", as well as at physiological versus pharmacological concentrations. Collectively, this study offers insights into novel molecular mechanisms by which menopause sets, and E2 replacement reverses, a pro-diabetogenic state, and further advances our knowledge on the mechanisms behind tissue-specific effects of estrogens. The present findings reveal new horizons in the development of novel pharmacological interventions to prevent metabolic dysfunction in naturally or surgically-induced post-menopausal women.
Book Synopsis Diagnosis and Management of Ovarian Disorders by : Albert Altchek
Download or read book Diagnosis and Management of Ovarian Disorders written by Albert Altchek and published by Elsevier. This book was released on 2003-09-04 with total page 595 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated second edition of Diagnosis and Management of Ovarian Disorders provides thorough, yet succinct insight into the ever-changing realm of ovarian disorders. It presents a novel multidisciplinary approach to the subject as described by clinicians, surgeons, pathologists, basic scientists and related medical researchers. Topics covered include reproductive technology, early diagnosis of ovarian cancer, and management of menopause among others. The breadth of information provided by this book will appeal to clinicians and researchers involved in the study and treatment of ovarian disorders.KEY FEATURES* Includes updated information on early diagnosis of ovarian cancer* Reviews new diagnostic techniques for ovarian disorders* Discusses latest information on reproductive technology* Presents translational treatment linking laboratory research with clinical medicine
Book Synopsis Exercise and Diabetes by : Sheri R. Colberg
Download or read book Exercise and Diabetes written by Sheri R. Colberg and published by American Diabetes Association. This book was released on 2013-05-30 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physical movement has a positive effect on physical fitness, morbidity, and mortality in individuals with diabetes. Although exercise has long been considered a cornerstone of diabetes management, many health care providers fail to prescribe it. In addition, many fitness professionals may be unaware of the complexities of including physical activity in the management of diabetes. Giving patients or clients a full exercise prescription that take other chronic conditions commonly accompanying diabetes into account may be too time-consuming for or beyond the expertise of many health care and fitness professionals. The purpose of this book is to cover the recommended types and quantities of physical activities that can and should be undertaken by all individuals with any type of diabetes, along with precautions related to medication use and diabetes-related health complications. Medications used to control diabetes should augment lifestyle improvements like increased daily physical activity rather than replace them. Up until now, professional books with exercise information and prescriptions were not timely or interactive enough to easily provide busy professionals with access to the latest recommendations for each unique patient. However, simply instructing patients to “exercise more” is frequently not motivating or informative enough to get them regularly or safely active. This book is changing all that with its up-to-date and easy-to-prescribe exercise and physical activity recommendations and relevant case studies. Read and learn to quickly prescribe effective and appropriate exercise to everyone.
Author :Caroline J. Hollins Martin Publisher :Springer Science & Business Media ISBN 13 :1627033734 Total Pages :474 pages Book Rating :4.6/5 (27 download)
Book Synopsis Nutrition and Diet in Menopause by : Caroline J. Hollins Martin
Download or read book Nutrition and Diet in Menopause written by Caroline J. Hollins Martin and published by Springer Science & Business Media. This book was released on 2013-06-04 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nutrition and Diet in Menopause is a single comprehensive source that will provide readers with an understanding of menopause. Holistic in its approach, this volume is divided into five sections covering psychological, endocrine and lifestyle factors, metabolism and physiology, bone and nutrition, cancer and nutrition, cardiovascular factors and dietary supplements in menopause. In-depth chapters review the potential long term consequences of menopause on the overall health of women, not only at the physical level including hot flushes (flashes) , alterations to the genitourinary system, skin changes, decreased cardiovascular functions, hypertension, headache, back pain, and constipation. Written by international leaders and trendsetters, Nutrition and Diet in Menopause is essential reading for endocrinologists, cardiologists, nutritionists and all health care professionals who are interested in women’s health.
Book Synopsis Sex Hormone Replacement Therapy by : Henry Burger
Download or read book Sex Hormone Replacement Therapy written by Henry Burger and published by . This book was released on 2014-01-15 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Developmental Toxicology by : CaroleAKimmel
Download or read book Developmental Toxicology written by CaroleAKimmel and published by CRC Press. This book was released on 1994-06-30 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Second Edition of this highly regarded work provides a state-of-the-art review of developmental toxicology from basic science, clinical, epidemiological, and regulatory perspectives. This new edition highlights the latest approaches to understanding the mechanisms of developmental toxicity, testing pharmaceutical and environmental agents, and interpreting developmental toxicity data.; The contributors demonstrate how new information on molecular embryology and cell biology is being applied to problems in developmental toxicology. Chapters describe the effects of toxic exposure on the functional development of various organs, examine the relationship between maternal and developmental toxicity, and discuss current techniques for studying chemical disposition, metabolism, and placental transfer. Close attention is given to the use of mathematical and statistical techniques in data interpretation, as well as to the regulatory aspects of testing and risk assessment. Other chapters focus on pre- and post conceptional clinical care and on genetic factors in clinical developmental toxicology.
