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Inflammatory Bowel Disease From Bench To Bedside
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Book Synopsis Inflammatory Bowel Disease: From Bench to Bedside by : Stephan R. Targan
Download or read book Inflammatory Bowel Disease: From Bench to Bedside written by Stephan R. Targan and published by Boom Koninklijke Uitgevers. This book was released on 2003-01-31 with total page 928 pages. Available in PDF, EPUB and Kindle. Book excerpt: A detailed and comprehensive story of the local and systemic pathophysiology of intestinal inflammation including management strategies. Research advances and current concepts of etiopathogenesis in the context of what is already known of the clinicopathologic features of these disorders are explored. This volume blends recent advances in the basic and clinical sciences as they relate to inflammatory bowel disease and emphasizes the effectiveness of a team approach of basic scientists and clinician investigators in this field.
Book Synopsis Inflammatory Bowel Disease by : Stephan R. Targan
Download or read book Inflammatory Bowel Disease written by Stephan R. Targan and published by Springer Science & Business Media. This book was released on 2007-05-16 with total page 891 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inflammatory Bowel Disease: From Bench to Bedside is a detailed and comprehensive story of the local and systemic pathophysiology of intestinal inflammation including management strategies. Research advances and current concepts of etiopathogenesis in the context of what is already known of the clinicopathologic features of these disorders is explored. This volume blends recent advances in the basic and clinical sciences as they relate to inflammatory bowel disease and emphasizes the effectiveness of a team approach of basic scientists and clinician investigators in this field.
Book Synopsis Crohn's Disease and Ulcerative Colitis by : Daniel C. Baumgart
Download or read book Crohn's Disease and Ulcerative Colitis written by Daniel C. Baumgart and published by Springer. This book was released on 2017-03-01 with total page 671 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition is a unique combined resource for physicians and scientists addressing the needs of both groups. In addition to stimulating exchange and collaboration and shortening the path between discovery and application of new knowledge, the book helps clinicians understand new therapeutic concepts from their origins. The volume serves as a comprehensive guide to the current diagnostic modalities, including enhanced imaging techniques such as MRI and CT enterography, virtual colonoscopy, ultrasound, and endomicroscopy, as well as conventional and complex immunomodulatory principles. The latest edition also includes revised chapters from the previous edition, as well as new chapters reflecting current developments in the field. Written by experts in their field, Crohn’s Disease and Ulcerative Colitis: From Epidemiology and Immunobiology to a Rational Diagnostic and Therapeutic Approach, Second Edition is of great value to gastroenterologists, surgeons, internists, pediatricians and gynecologists trainees, as well as all those involved in Crohn’s disease, ulcerative colitis, and related autoimmune disorders.
Book Synopsis Colonic Motility by : Sushil K. Sarna
Download or read book Colonic Motility written by Sushil K. Sarna and published by Biota Publishing. This book was released on 2010-11-01 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: Three distinct types of contractions perform colonic motility functions. Rhythmic phasic contractions (RPCs) cause slow net distal propulsion with extensive mixing/turning over. Infrequently occurring giant migrating contractions (GMCs) produce mass movements. Tonic contractions aid RPCs in their motor function. The spatiotemporal patterns of these contractions differ markedly. The amplitude and distance of propagation of a GMC are several-fold larger than those of an RPC. The enteric neurons and smooth muscle cells are the core regulators of all three types of contractions. The regulation of contractions by these mechanisms is modifiable by extrinsic factors: CNS, autonomic neurons, hormones, inflammatory mediators, and stress mediators. Only the GMCs produce descending inhibition, which accommodates the large bolus being propelled without increasing muscle tone. The strong compression of the colon wall generates afferent signals that are below nociceptive threshold in healthy subjects. However, these signals become nociceptive; if the amplitudes of GMCs increase, afferent nerves become hypersensitive, or descending inhibition is impaired. The GMCs also provide the force for rapid propulsion of feces and descending inhibition to relax the internal anal sphincter during defecation. The dysregulation of GMCs is a major factor in colonic motility disorders: irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and diverticular disease (DD). Frequent mass movements by GMCs cause diarrhea in diarrhea predominant IBS, IBD, and DD, while a decrease in the frequency of GMCs causes constipation. The GMCs generate the afferent signals for intermittent short-lived episodes of abdominal cramping in these disorders. Epigenetic dysregulation due to adverse events in early life is one of the major factors in generating the symptoms of IBS in adulthood.
Book Synopsis Inflammatory Bowel Disease by : Stephan R. Targan
Download or read book Inflammatory Bowel Disease written by Stephan R. Targan and published by John Wiley & Sons. This book was released on 2011-08-24 with total page 1429 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the state-of–the-art book on inflammatory bowel disease you have been waiting for Written and edited by international experts in gastroenterology this up-to-date volume provides a complete review of the basic science behind inflammatory bowel disease (IBD), as well as evidence-based clinical guidance on diagnosis, treatment and long-term management of IBD. In 50 chapters the authors cover the latest and most promising treatment modalities and the science behind them. There are chapters which cover the advances in the medical and surgical treatment of conditions such as Crohn's disease and ulcerative colitis, as well as chapters focusing on nutrition, imaging and complementary medicine. This is an invaluable information resource for all those in the medical team treating patients with IBD. Whether you are a gastroenterologist, gastrointestinal surgeon or GI nurse specialist this book deserves a place in your library.
Book Synopsis Personalizing Treatment In IBD: Hype or Reality In 2020? by : Fernando Gomollón
Download or read book Personalizing Treatment In IBD: Hype or Reality In 2020? written by Fernando Gomollón and published by Frontiers Media SA. This book was released on 2021-07-05 with total page 119 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Kirsner's Inflammatory Bowel Diseases by : Joseph B. Kirsner
Download or read book Kirsner's Inflammatory Bowel Diseases written by Joseph B. Kirsner and published by Elsevier Health Sciences. This book was released on 2004 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive New Edition describes all of the latest scientific and clinical advances in the field of inflammatory bowel disease (IBD). A new editorial team-joined by a superb group of international authorities-examine every aspect of IBD-including etiology and pathogenesis, diagnosis and evaluation, medical and surgical therapy, and more. A wealth of expanded coverage, additional international contributors, extensive updating throughout, and numerous diagnostic and therapeutic algorithms make this an essential resource. Emphasizes evidence-based medicine in the section on medical therapy. Features a detailed description of inflammatory and immunologic pathways, allowing the reader to fully understand the contributing influences to the inflammation of IBD. Presents separate chapters on molecular genetics and clinical genetics for more in-depth coverage of each aspect of inflammatory bowel disease genetics. Provides a comprehensive review of IBD through abundant, high-quality endoscopic, radiographic, and histologic photographs-placing the various diagnostic modalities in perspective. Offers extensive coverage of postoperative recurrence of Crohn's disease · pouchitis · microscopic colitis · perianal disease · and osteoporosis. Includes up-to-the-minute guidance (including many 2003 references). Features a new editorial team, joined by numerous new contributors who provide fresh, global perspectives. Includes nine new chapters. Offers expanded coverage throughout, and through revisions of all pre-existing chapters. With over 75 additional contributing experts.
Book Synopsis Colitis-Associated Cancer by : Masato Kusunoki
Download or read book Colitis-Associated Cancer written by Masato Kusunoki and published by Springer. This book was released on 2015-10-01 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the number of patients with colitis-associated cancer (CAC) is on the increase, the purpose of this book is to review the latest topics concerning management of the disease. In recent years, the diagnostic power of endoscopy and molecular pathology has also grown tremendously, as a result of which they now have a far greater influence on the treatment of CAC. At the moment, appropriate monitoring programs for ulcerative colitis and Crohn’s disease remain uncertain. At the same time, the latest findings on DNA methylation and microRNAs hold the promise of making revolutionary changes in these areas. Moreover, recent drug advances in the treatment of inflammatory bowel diseases have changed surgical indications. On the other hand, the indication of mucosectomy on colorectal cancer in ulcerative colitis and prophylactic abdominoperineal resection for Crohn’s disease remain controversial. This book provides the latest information on the remaining issues of CAC from the point of view of expert surgeons.
Book Synopsis Chasing Men on Fire by : Stephen G. Waxman
Download or read book Chasing Men on Fire written by Stephen G. Waxman and published by MIT Press. This book was released on 2018-03-09 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: A thirty-year quest, from genes to pain-signaling neurons to people with a rare genetic disorder that makes them feel they are on fire. Two soldiers, both with wounds injuring the same nerve, show very different responses: one is disabled by neuropathic pain, unable to touch the injured limb because even the lightest contact triggers excruciating discomfort; the other notices numbness but no pain at all. Could the difference lie in their genes? In this book, described in the foreword by Nobel Laureate James Rothman as “so well written that it reads like a detective novel,” Stephen Waxman recounts the search for a gene that controls pain—a search spanning more than thirty years and three continents. The story moves from genes to pain-signaling neurons that scream when they should be silent to people with a rare genetic disorder who feel they are on fire. Waxman explains that if pain-signaling neurons are injured by trauma or disease, they can become hyperactive and send pain signals to the brain even without external stimulus. Studying the hyperactive mutant pain gene in man on fire syndrome has pointed the way to molecules that produce pain more broadly within the general population, in the rest of us. Waxman's account of the many steps that led to discovery of the pain gene tells the story behind the science, of how science happens.
Book Synopsis Fibrostenotic Inflammatory Bowel Disease by : Florian Rieder
Download or read book Fibrostenotic Inflammatory Bowel Disease written by Florian Rieder and published by Springer. This book was released on 2018-09-04 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive account of the pathogenesis and treatment of intestinal fibrosis, covering both the clinical and molecular aspects of the disease. It begins by describing the epidemiology and genetics of fibrostenosing IBD in Crohn’s disease and Ulcerative colitis as well as the epigenetics and cellular and molecular mechanisms of the disease. Readers will obtain an in-depth overview of the disease from biomarkers and histology to surgical intervention, imaging and current and future drug therapies. Medical management of fibrosis, endoscopy and imaging as well as surgical approaches are all discussed. Through the links to videos contained in the book, the reader will become familiar with interventional procedures such as endoscopic balloon dilation and surgical techniques for stricturing IBD, such as resection and strictureplasties. This is an indispensable volume for anyone working on fibrostenotic IBD, such as gastroenterologists, internists, radiologists, colorectal surgeons, pathologists and researchers. It has been written by a team of top experts from North America, Asia and Europe.
Book Synopsis Equine Acute Abdomen by : Nathaniel A. White
Download or read book Equine Acute Abdomen written by Nathaniel A. White and published by CRC Press. This book was released on 2009-10-31 with total page 772 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title allows users to effectively diagnose and treat any acute disease of the stomach, intestines, peritoneum, liver, and abdominal wall. Its authorship includes over 20 internationally recognized experts that provide critical information needed by practitioners for management of abdominal diseases. This informative resource provides a thorough discussion of normal and abnormal anatomy and physiology. Surgical techniques are broken down into an easy-to-read step-by-step format. This highly visual presentation, with over 410 illustrations, is a necessary edition to an equine practitioner’s library. Published by Teton New Media in the USA and distributed by Manson Publishing outside of North America.
Book Synopsis Inflammatory Bowel Disease by : M. Campieri
Download or read book Inflammatory Bowel Disease written by M. Campieri and published by Springer Science & Business Media. This book was released on 2002-03-31 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the proceedings of the Falk Symposium No. 122 on "Inflammatory Bowel Disease - A Clinical Case Approach to Pathophysiology, Diagnosis, and Treatment", held in Bologna, Italy, on June 22-23, 2001, and deals with some major issues concerning Genetics of IBD, Pediatrics in IBD, Early vs Late IBD, Bacteria and Gut Inflammation, Refractory CD, Fistulizing CD, Refractory Distal Colitis, and Complications of Ileal-Pouch Anastomosis. The main aim of the meeting was to highlight the value of an integrated clinical approach and the importance of clinical research in developing innovative methods of treatment.
Book Synopsis Inflammatory Bowel Disease Nursing by : Kathy Whayman
Download or read book Inflammatory Bowel Disease Nursing written by Kathy Whayman and published by Mark Allen Group. This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first nursing book of its kind, focusing on the positioning of nurses within the multidisciplinary team, and outlining their role in the assessment, planning, implementation and evaluation of care in Inflammatory Bowel Disease Nursing. It presents ways for nurses to provide continuity of care, support and information to patients from diagnosis onwards to achieve the best quality of life.
Book Synopsis Molecular Genetics of Inflammatory Bowel Disease by : Mauro D'Amato
Download or read book Molecular Genetics of Inflammatory Bowel Disease written by Mauro D'Amato and published by Springer Science & Business Media. This book was released on 2013-10-05 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research in Crohn’s disease (CD) and ulcerative colitis (UC), together known as the inflammatory bowel diseases (IBD), has truly seen a revolution in the last 5-10 years. This book examines how these genetic discoveries have led to the identification of biological functions not previously associated with IBD pathophysiology (e.g. autophagy), how multiple genetic risk factors for IBD converge on given biological functions and that together the identified variants in these genes have predisposing and protective roles (e.g. the multiple variants in the receptor for the IL23 cytokine and its signaling cascade), and how having such a large number of known genetic risk factors has changed our understanding not only about the genetic and molecular overlap between CD and UC, but also between these diseases and other chronic inflammatory diseases (e.g. psoriasis, multiple sclerosis, type 1 diabetes and many others).
Book Synopsis Biomarkers in Inflammatory Bowel Diseases by : Nik Sheng Ding
Download or read book Biomarkers in Inflammatory Bowel Diseases written by Nik Sheng Ding and published by Springer. This book was released on 2019-05-13 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive and complete overview of biomarkers in clinical practice for inflammatory bowel disease (IBD) bringing together the literature in a clear and concise manner. The book bridges the gap between growing knowledge at the bench and current and future applications of biomarkers in clinical practice. The central structure of the book focuses on prognostic and predictive biomarkers in IBD with an emphasis on the fields of research and scientific techniques (genomics, proteomics and metabonomics) that have led to biomarker discovery and places these biomarkers within a clinical context to help understand their utility in clinical practice. This book will be of use to clinicians who have an interest in using biomarkers in clinical practice as well as clinician researchers and scientists involved in the biomarker research pipeline. The author team comprises experts from around the world in order to bring together the literature in an effort to inform clinicians and researchers about the current state-of-the art in biomarker discovery. It is intended to assist future research efforts and indicate how biomarkers might be best applied to clinical practice both at present and in the future.
Book Synopsis Inflammatory Bowel Diseases by : G.N. Tytgat
Download or read book Inflammatory Bowel Diseases written by G.N. Tytgat and published by Springer Science & Business Media. This book was released on 1995-12-31 with total page 746 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is currently an explosive growth of basic and clinical research in inflammatory bowel diseases. The extensive interest of the medical community in these diseases is largely explained by the devastating impact the illnesses have on the quality of life, their high prevalence in the community, and the fact that so many medical disciplines are involved in tackling the immensely complex studies on pathogenesis, clinical expression and treatment possibilities. The Falk Symposium No. 85 held in The Hague, the Netherlands, 29 June-1 July 1995 brought together over 80 speakers and 1000 participants from all over the world. Plenary sessions and workshops allowed the discussion of basic and clinical research, enabling appropriate choices to be made. Topics reflected areas of high current basic research interest, clinical importance, and actual or future treatment potential. Audience: An important work for all disciplines involved in research and therapy of inflammatory bowel diseases.
Book Synopsis Inflammation, 4 Volume Set by : Jean-Marc Cavaillon
Download or read book Inflammation, 4 Volume Set written by Jean-Marc Cavaillon and published by John Wiley & Sons. This book was released on 2018-02-20 with total page 1818 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dieses Fachbuch erläutert die molekularen Grundlagen von Entzündungen, spannt den Bogen zu Infektionskrankheiten und den Zusammenhang zwischen Entzündungen und chronischen Erkrankungen, behandelt abschließend den Heilungsprozess und zeigt Therapiemöglichkeiten.