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Inflammation In The Pathogenesis Of Chronic Diseases
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Book Synopsis Inflammation in the Pathogenesis of Chronic Diseases by : Randall E. Harris
Download or read book Inflammation in the Pathogenesis of Chronic Diseases written by Randall E. Harris and published by Springer Science & Business Media. This book was released on 2007-05-09 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, a worldwide panel of leading experts discuss the role of inflammation in the pathogenesis of major chronic diseases and the current controversy regarding risk versus benefit of selective cyclooxygenase-2 (COX-2) inhibitors. The authors provide exciting and enlightening perspectives on COX-2 and related molecular targets in the future of medicine, including historical perspectives.
Book Synopsis Inflammation, Lifestyle and Chronic Diseases by : Bharat B. Aggarwal
Download or read book Inflammation, Lifestyle and Chronic Diseases written by Bharat B. Aggarwal and published by CRC Press. This book was released on 2016-04-19 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxidative stress and inflammation are among the most important factors of disease. Chronic infections, obesity, alcohol and tobacco usage, radiation, environmental pollutants, and high-calorie diets have been recognized as major risk factors for a variety of chronic diseases from cancer to metabolic diseases. All these risk factors are linked to ch
Book Synopsis The Infectious Etiology of Chronic Diseases by : Institute of Medicine
Download or read book The Infectious Etiology of Chronic Diseases written by Institute of Medicine and published by National Academies Press. This book was released on 2004-07-16 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, a number of chronic diseases have been linked, in some cases definitively, to an infectious etiology: peptic ulcer disease with Helicobacter pylori, cervical cancer with several human papillomaviruses, Lyme arthritis and neuroborreliosis with Borrelia burgdorferi, AIDS with the human immunodeficiency virus, liver cancer and cirrhosis with hepatitis B and C viruses, to name a few. The proven and suspected roles of microbes does not stop with physical ailments; infections are increasingly being examined as associated causes of or possible contributors to a variety of serious, chronic neuropsychiatric disorders and to developmental problems, especially in children. The Infectious Etiology of Chronic Diseases: Defining the Relationship, Enhancing the Research, and Mitigating the Effects, summarizes a two-day workshop held by the Institute of Medicine's Forum on Microbial Threats to address this rapidly evolving field. Participants explored factors driving infectious etiologies of chronic diseases of prominence, identified difficulties in linking infectious agents with chronic outcomes, and discussed broad-based strategies and research programs to advance the field.
Book Synopsis Chronic Inflammation by : Sashwati Roy
Download or read book Chronic Inflammation written by Sashwati Roy and published by CRC Press. This book was released on 2012-09-17 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although acute inflammation is a healthy physiological response indicative of wound healing, chronic inflammation has been directly implicated in a wide range of degenerative human health disorders encompassing almost all present day non-communicable diseases including autoimmune diseases, obesity, diabetes and atherosclerosis. Chronic Inflammation
Book Synopsis Regulation of Inflammation in Chronic Disease by : Jixin Zhong
Download or read book Regulation of Inflammation in Chronic Disease written by Jixin Zhong and published by Frontiers Media SA. This book was released on 2019-07-19 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Book Synopsis The Physiology of Inflammation – The Final Common Pathway to Disease by : Alexandrina Ferreira Mendes
Download or read book The Physiology of Inflammation – The Final Common Pathway to Disease written by Alexandrina Ferreira Mendes and published by Frontiers Media SA. This book was released on 2019-02-20 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic diseases are increasingly recognized as involving low grade inflammation, that is, a self-perpetuating tissue response to stress caused by exogenous or endogenous triggers, that progressively evokes danger-associated molecular pattern release, ultimately driving tissue damage and loss of function. This response is frequently unapparent clinically, thus the designation "low grade". This eBook comprises nineteen reviews and original articles that provide the most updated knowledge on the causes and roles of this inflammatory response in a variety of diseases and conditions. The editorial that precedes these articles not only summarizes each one, but provides a broader interpretation of the role of inflammation in health and a variety of disease conditions, the underlying mechanisms and the targets more promising for therapy. Finally, it also highlights the most relevant and emerging research topics that are already shaping future directions for the development of more fine-tuned and innovative therapies.
Book Synopsis The Origin of Chronic Inflammatory Systemic Diseases and their Sequelae by : Rainer Straub
Download or read book The Origin of Chronic Inflammatory Systemic Diseases and their Sequelae written by Rainer Straub and published by Academic Press. This book was released on 2015-04-08 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic inflammatory diseases such as rheumatoid arthritis, ankylosing spondylitis, multiple sclerosis, inflammatory bowel diseases, and others typically stimulate a systemic response of the entire body. This response has a uniform character in many diseases because common pathways are switched on. The uniform response regulates systemic energy and water provision. However, long-term application of this program leads to typical disease sequelae such as fatigue / depressive symptoms, sleep disturbances, anorexia, malnutrition, muscle wasting – cachexia, cachectic obesity, insulin resistance, dyslipidemia, alterations of steroid hormone axes, disturbances of the hypothalamic-pituitary-gonadal axis, elevated sympathetic tone, hypertension, volume expansion, decreased parasympathetic tone, inflammation–related anemia, bone loss, hypercoagulability, circadian rhythms of symptoms, and disease exacerbation by stress . The Origin of Chronic Inflammatory Systemic Diseases and Their Sequelae demonstrates concepts of neuroendocrine immunology, energy and water regulation, and evolutionary medicine in order to show that the uniform response that regulates systemic energy and water provision, has been positively selected for acute physiological responses and short-lived disease states, but is a misguided program in chronic inflammatory diseases and aging. Offers a broad conceptual framework with a strong clinical link, written in an easy to grasp style and demonstrating the link to aging research Describes the important principles derived from basic immunology that are used to explain pathogenesis of chronic inflammatory systemic diseases with a focus on autoimmunity Defines the bioenergetics and energy regulation of the body explaining common response pathways typical for systemic inflammation Makes use of evolutionary medicine theory to demonstrate the uniformity of the systemic response Explains the appearance of typical disease sequelae on the basis of the three pillars: neuroendocrine immunology, energy regulation, and evolutionary medicine theory Contains color figures and tables that explain the field to newcomers
Book Synopsis Mitochondrial Dysfunction by : Lawrence H. Lash
Download or read book Mitochondrial Dysfunction written by Lawrence H. Lash and published by Elsevier. This book was released on 2013-10-22 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods in Toxicology, Volume 2: Mitochondrial Dysfunction provides a source of methods, techniques, and experimental approaches for studying the role of abnormal mitochondrial function in cell injury. The book discusses the methods for the preparation and basic functional assessment of mitochondria from liver, kidney, muscle, and brain; the methods for assessing mitochondrial dysfunction in vivo and in intact organs; and the structural aspects of mitochondrial dysfunction are addressed. The text also describes chemical detoxification and metabolism as well as specific metabolic reactions that are especially important targets or indicators of damage. The methods for measurement of alterations in fatty acid and phospholipid metabolism and for the analysis and manipulation of oxidative injury and antioxidant systems are also considered. The book further tackles additional methods on mitochondrial energetics and transport processes; approaches for assessing impaired function of mitochondria; and genetic and developmental aspects of mitochondrial disease and toxicology. The text also looks into mitochondrial DNA synthesis, covalent binding to mitochondrial DNA, DNA repair, and mitochondrial dysfunction in the context of developing individuals and cellular differentiation. Microbiologists, toxicologists, biochemists, and molecular pharmacologists will find the book invaluable.
Book Synopsis The Link Between Inflammation and Cancer by : Angus G. Dalgleish
Download or read book The Link Between Inflammation and Cancer written by Angus G. Dalgleish and published by Springer Science & Business Media. This book was released on 2006-03-05 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: A link between inflammation and cancer has been established many years ago, yet it is only recently that the potential significance of this connection has become apparent. Although several examples of chronic inflammatory conditions, often induced by persistent irritation and/or infection, developing into cancer have been known for some time, there has been a notable resistance to contemplate the possibility that this association may apply in a causative way to other cancers. Examples for such progression from chronic inflammation to cancer are colon carcinoma developing with increased frequency in patients with ulcerative colitis, and the increased incidence of bladder cancer in patients suffering from chronic Schistosoma infection. Inflammation and cancer have been recognized to be linked in another context for many years, i.e., with regards to pathologies resembling chronic lacerations or 'wounds that do not heal.' More recently, the immunology of wound healing has given us clues as to the mechanistic link between inflammation and cancer, in as much as wounds and chronic inflammation turn off local cell-mediated immune responses and switch on growth factor release as well the growth of new blood vessels - angiogenesis. Both of these are features of most types of tumours, which suggest that tumours may require an immunologically shielded milieu and a growth factor-rich environment.
Book Synopsis Hyperuricemic Syndromes by : Claudio Ronco
Download or read book Hyperuricemic Syndromes written by Claudio Ronco and published by Karger Medical and Scientific Publishers. This book was released on 2005-01-01 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: Uric acid disorders are involved in both nephrological and hematological diseases. One of these crystal-associated diseases which has been known since antiquity is gout. More recently, tumor Lysis syndromes have been identified which affect patients with cancer, especially in the phase of cellular destruction after chemotherapy. The detection of these hyperuricemic syndromes, together with the improved understanding of urate handling by the kidney, have spurred new interest in the pathophysiology of hyperuricemic states, their clinical consequences and management. Moreover, the recent development of a recombinant form of urate oxidase transforming uric acid into allantoin (Rasburicase) has caused new interest in the pathophysiology of hyperuricemia and the potential applications of this new drug. The multidisciplinary approach of this book offers new insights into the metabolic syndromes in question by uniting authors from the fields of biochemistry, pharmacology, rheumatology, onco-hematology, and nephrology. The result is a compendium of the present knowledge in the field, which will also be very useful as a reference tool for professionals and students who want to expand their knowledge on this topic.
Book Synopsis Chronic Inflammation by : Sashwati Roy
Download or read book Chronic Inflammation written by Sashwati Roy and published by CRC Press. This book was released on 2016-10 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although acute inflammation is a healthy physiological response indicative of wound healing, chronic inflammation has been directly implicated in a wide range of degenerative human health disorders encompassing almost all present day non-communicable diseases including autoimmune diseases, obesity, diabetes and atherosclerosis. Chronic Inflammation: Molecular Pathophysiology, Nutritional and Therapeutic Interventions provides an exposition of the process of chronic inflammation in three parts: Systems Biology of Inflammation and Regulatory Mechanisms describes the process of chronic inflammation including initiation, progression, and resolution. Pathologies Associated with Inflammation gives a rigorous and critical treatment of specific human health disorders where chronic inflammation plays a major role. Nutrition & Therapeutics for Inflammatory Diseases details the protective abilities of structurally diverse antioxidants, phytochemicals, anti-inflammatory diets, omega-3 fatty acids, NSAIDs, disease modifying anti-rheumatic drugs, and novel regimens. Designed for scientists as well as clinicians, Chronic Inflammation provides critical understanding of the key checkpoints that regulate chronic inflammation. Going beyond the epidemiology of chronic inflammation, the text covers regulatory mechanisms controlling inflammation initiation, progression, and resolution. The authors address pathologies associated with inflammation and provide various nutritional and therapeutic interventions for inflammatory diseases.
Book Synopsis Oxidative Stress and Inflammation in Non-communicable Diseases - Molecular Mechanisms and Perspectives in Therapeutics by : Jordi Camps
Download or read book Oxidative Stress and Inflammation in Non-communicable Diseases - Molecular Mechanisms and Perspectives in Therapeutics written by Jordi Camps and published by Springer. This book was released on 2014-07-19 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxidative stress and inflammation underpin most diseases; their mechanisms are inextricably linked. For example, chronic inflammation is associated with oxidation, anti-inflammatory cascades are linked to decreased oxidation, increased oxidative stress triggers inflammation and redox balance inhibits the inflammatory cellular response. Whether or not oxidative stress and inflammation represent the causes or the consequences of cellular pathology, they contribute significantly to the pathogenesis of non-communicable diseases. The incidence of obesity and other related metabolic disturbances are rising, as are age-related diseases due to progressively aging populations. Interrelations between the mechanisms of oxidative stress and of inflammatory signaling and metabolism are, in the broad sense of energy transformation, being increasingly recognized as part of the problem in non-communicable diseases. The book Oxidative Stress and Inflammation in Non-communicable Diseases: Molecular Mechanisms and Perspectives in Therapeutics is an update on the latest research on the molecular basis of non-communicable diseases and the search for possible therapeutic alternatives. The authors of this monograph are experts in their field and the book as a whole, provides an overview of the biochemical alterations underlying diseases such as cardiovascular disease, cancer, obesity, renal disease, neurological diseases and diabetes, emphasizing those aspects that they share in common. We hope that this book will be useful for researchers in biomedicine and also for physicians interested in finding the root causes of the disease, as well as for post-graduate students in biochemistry, molecular biology, nutrition or medicine.
Download or read book ABC of Obesity written by Naveed Sattar and published by John Wiley & Sons. This book was released on 2009-04-08 with total page 64 pages. Available in PDF, EPUB and Kindle. Book excerpt: Obesity is a hugely expensive and increasing problem worldwide,leading to disability, reproductive problems, depression andaccelerated metabolic and vascular diseases in a large proportionof men, women and children. The ABC of Obesity is a newguide which will aid its effective management, addressing issuessuch as dieting, exercise, self esteem, drug treatment and surgery.Recent evidence is used to highlight frequent problems, successfultreatment options, and the most common causes. Written by leading experts, this is a widely accessible text andan indispensable guide for all general practitioners, juniordoctors, nurses, and other healthcare professionals who areinvolved in the treatment and research of this commoncondition.
Book Synopsis Inflammation, Chronic Diseases and Cancer by : Mahin Khatami
Download or read book Inflammation, Chronic Diseases and Cancer written by Mahin Khatami and published by BoD – Books on Demand. This book was released on 2012-03-09 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a collection of excellent reviews and perspectives contributed by experts in the multidisciplinary field of basic science, clinical studies and treatment options for a wide range of acute and chronic inflammatory diseases or cancer. The goal has been to demonstrate that persistent or chronic (unresolved or subclinical) inflammation is a common denominator in the genesis, progression and manifestation of many illnesses and/or cancers, particularly during the aging process. Understanding the fundamental basis of shared and interrelated immunological features of unresolved inflammation in initiation and progression of chronic diseases or cancer are expected to hold real promises when the designs of cost-effective strategies are considered for diagnosis, prevention or treatment of a number of age-associated illnesses such as autoimmune and neurodegenerative diseases as well as many cancers.
Book Synopsis Inflammation: Natural Resources and Its Applications by : Parag Jain
Download or read book Inflammation: Natural Resources and Its Applications written by Parag Jain and published by Springer. This book was released on 2014-12-04 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inflammation is the very natural process of our body; it does its work immediately and smoothly along with lots of helpers. Inflammation is linked to immune system as acute inflammatory or pro-inflammatory phase through macrophage activation. This book is for researchers and scholars in the field of life sciences and medical sciences. The book contains all inflammatory sources around the world. It emphasizes on anti-inflammatory sources along with its active inflammatory constituents and other medicinal uses with authentic references. Anti-inflammation is a kind of activity with is found in nearly all of the natural sources used for major biological activities. So, the book helps them to correlate their activity of interest with anti-inflammatory source. The present work deals with illustrative representation of inflammation, causes of inflammation, inflammatory mediators, anti-inflammatory sources other uses and inflammation and lifestyle. It mainly provides the researchers the updated information from the ancient to the most recent ongoing research on inflammation. This book imparts pace to their idea of thinking, assist to make clear predictions before proceeding to research. The introduction includes natural sources of inflammation and its benefits; the sources are from plant, animal and marine. The book tells how these sources are useful for us to cure several diseases and opens new path for further research. Inflammation part of the book is well presented along with its phases, types and other diseases interrelated with inflammation. Inflammatory mediators, the foremost player of inflammation are defined in a very pleasant and convenient manner. The chapter includes both cell- derived and plasma - derived mediators illustratively with their synthesis and action. Natural source of anti-inflammation is the heart chapter of this book which contains all anti-inflammation sources from plants, marine and animals. This chapter also contains short description of most of the sources, its availability and uses. The authors have also added inflammatory models for assessment of biological activities of natural sources both in vitro and in vivo. Inflammation free lifestyle is described very nicely in the book. The contents are very specific and relevant to its topic; all the data provided is unique and useful. The anti-inflammatory table includes sources, plant parts used, active constituents and other uses. This data provides ample information regarding anti-inflammatory research and innovation. The highlights of this book shall be: -Describes almost all anti-inflammatory sources around the globe at one place in a more convenient tabulated form -Illustrative representation makes the book more attractive and interactive
Book Synopsis The Impact of Nutrition and Statins on Cardiovascular Diseases by : Ioannis Zabetakis
Download or read book The Impact of Nutrition and Statins on Cardiovascular Diseases written by Ioannis Zabetakis and published by Academic Press. This book was released on 2019-01-15 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Impact of Nutrition and Statins on Cardiovascular Diseases presents a summary of the background information and published research on the role of food in inhibiting the development of cardiovascular diseases. Written from a food science, food chemistry, and food biochemistry perspective, the book provides insights on the origin of cardiovascular diseases, an analysis of statin therapy, their side effects, and the role of dietary intervention as an alternative solution to preventing cardiovascular diseases. It focuses on the efficacy of nutrition and statins to address inflammation and inhibit the onset of disease, while also providing nutrition information and suggested dietary interventions. Includes a bioscience approach that focuses on inflammation and revisits the lipid hypothesis Presents the view that nutritional interventions have considerable value, not only for reducing cardiovascular risk for CVDs patients, but also acting as the best precaution for otherwise healthy people Advocates that nutritional habits that are formed at a young age are the best way to tackle the global epidemic that is CVDs
Book Synopsis The Metabolic Ghetto by : Jonathan C. K. Wells
Download or read book The Metabolic Ghetto written by Jonathan C. K. Wells and published by Cambridge University Press. This book was released on 2016-07-21 with total page 625 pages. Available in PDF, EPUB and Kindle. Book excerpt: A multidisciplinary analysis of the role of nutrition in generating hierarchical societies and cultivating a global epidemic of chronic diseases.
