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Inflammation And Idiosyncratic Drug Reactions
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Book Synopsis Neutrophils and Idiosyncratic Advese [sic] Drug Reactions Resulting from Inflammation-drug Interaction by : Xiaomin Deng
Download or read book Neutrophils and Idiosyncratic Advese [sic] Drug Reactions Resulting from Inflammation-drug Interaction written by Xiaomin Deng and published by . This book was released on 2008 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Drug-Induced Liver Injury written by and published by Academic Press. This book was released on 2019-07-13 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. Includes the authority and expertise of leading contributors in pharmacology Presents the latest release in the Advances in Pharmacology series
Book Synopsis Adverse Reactions to Non-Steroidal Anti-Inflammatory Drugs: Clinical Pharmacoepidemiology by : M. Kurowski
Download or read book Adverse Reactions to Non-Steroidal Anti-Inflammatory Drugs: Clinical Pharmacoepidemiology written by M. Kurowski and published by Birkhäuser. This book was released on 1992-07-17 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt: Non-steroidal anti-inflammatory drugs (NSAIDs) are among the mostfrequently prescribed drugs in the Western world. During the past decade a large number of new compounds were marketed, some of which had to be withdrawn after a short while because of adverse drug reactions. These experiences led to an under standing that a complete picture of the safety of these drugs can only be obtained after their introduction into the marketplace. Differentmethods ofpost-marketing surveillance (PMS) serve as important tools for monitoring the frequency of adverse reactions and for generating and corroborating hypotheses. Experience with PMS has thusfar been quite limited in Germany. In 1987 a non-profit organization, "Verein zur Langzeituntersuchung von Arzneimittel wirkungen auf dem Gebiet der Rheumatologie e. V. " (VLAR) was founded by interested physicians and pharmacologists to raise funds and perform investiga tions on the safety of NSAIDs. The first project by the VLAR, SPALA ("Safety Profile of Antirheumatics in Long-Term Administration"), was sponsored by F. Hoffmann-La Roche AG (Basel, Switzerland). In July 1990, when the project was successfully terminated, almost 30,000 patients had been completely docu mented and their medical records entered into a computer for subsequent review by a select panel of experts with experience in monitoring adverse reactions to NSAIDs. The comments, criticisms, and ideas of these experts were brought togetherat a symposium organized by the VLAR at the Klinikum Steglitz (Berlin, Germany) on 12 October 1990.
Book Synopsis Hepatotoxicity by : Hyman J. Zimmerman
Download or read book Hepatotoxicity written by Hyman J. Zimmerman and published by Lippincott Williams & Wilkins. This book was released on 1999 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.
Book Synopsis Inflammation and Idiosyncratic Drug Reactions by : James Parker Luyendyk
Download or read book Inflammation and Idiosyncratic Drug Reactions written by James Parker Luyendyk and published by . This book was released on 2004 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Adverse Reactions to Non-Steroidal Anti-Inflammatory Drugs: Clinical Pharmacoepidemiology by : M. Kurowski
Download or read book Adverse Reactions to Non-Steroidal Anti-Inflammatory Drugs: Clinical Pharmacoepidemiology written by M. Kurowski and published by Birkhäuser. This book was released on 2014-08-23 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt: Non-steroidal anti-inflammatory drugs (NSAIDs) are among the mostfrequently prescribed drugs in the Western world. During the past decade a large number of new compounds were marketed, some of which had to be withdrawn after a short while because of adverse drug reactions. These experiences led to an under standing that a complete picture of the safety of these drugs can only be obtained after their introduction into the marketplace. Differentmethods ofpost-marketing surveillance (PMS) serve as important tools for monitoring the frequency of adverse reactions and for generating and corroborating hypotheses. Experience with PMS has thusfar been quite limited in Germany. In 1987 a non-profit organization, "Verein zur Langzeituntersuchung von Arzneimittel wirkungen auf dem Gebiet der Rheumatologie e. V. " (VLAR) was founded by interested physicians and pharmacologists to raise funds and perform investiga tions on the safety of NSAIDs. The first project by the VLAR, SPALA ("Safety Profile of Antirheumatics in Long-Term Administration"), was sponsored by F. Hoffmann-La Roche AG (Basel, Switzerland). In July 1990, when the project was successfully terminated, almost 30,000 patients had been completely docu mented and their medical records entered into a computer for subsequent review by a select panel of experts with experience in monitoring adverse reactions to NSAIDs. The comments, criticisms, and ideas of these experts were brought togetherat a symposium organized by the VLAR at the Klinikum Steglitz (Berlin, Germany) on 12 October 1990.
Book Synopsis Inflammation and Idiosyncratic Drug Reactions by : Patrick Joseph Shaw
Download or read book Inflammation and Idiosyncratic Drug Reactions written by Patrick Joseph Shaw and published by . This book was released on 2008 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Drug-Induced Liver Disease by : Neil Kaplowitz
Download or read book Drug-Induced Liver Disease written by Neil Kaplowitz and published by CRC Press. This book was released on 2002-10-16 with total page 790 pages. Available in PDF, EPUB and Kindle. Book excerpt: Featuring more than 4100 references, Drug-Induced Liver Disease will be an invaluable reference for gastroenterologists, hepatologists, family physicians, internists, pathologists, pharmacists, pharmacologists, and clinical toxicologists, and graduate and medical school students in these disciplines.
Book Synopsis Current Concepts in Drug Metabolism and Toxicology by :
Download or read book Current Concepts in Drug Metabolism and Toxicology written by and published by Academic Press. This book was released on 2012-11-27 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume of Advances in Pharmacology explores the current concepts in drug metabolism and toxicology. Chapters cover the Keap1-Nrf2 cell defense pathway, animal models of drug-induced idiosyncratic toxicity and the use of human embryonic and induced pluripotent stem cells for modeling metabolism and toxicity. With a variety of chapters and the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike. Explores the current concepts in drug metabolism and toxicology Chapters cover such areas as the Keap1-Nrf2 cell defense pathway, animal models of drug-induced idiosyncratic toxicity and the use of human embryonic and induced pluripotent stem cells for modeling metabolism and toxicity An essential resource for pharmacologists, immunologists and biochemists alike
Book Synopsis Sherlock's Diseases of the Liver and Biliary System by : James S. Dooley
Download or read book Sherlock's Diseases of the Liver and Biliary System written by James S. Dooley and published by John Wiley & Sons. This book was released on 2018-08-06 with total page 832 pages. Available in PDF, EPUB and Kindle. Book excerpt: A new, fully updated edition of the world’s most famous book on liver diseases—with updating of all areas and inclusion of new specific topics, by internationally renowned specialists This brand new edition of the classic book on hepatology provides a concise, clearly presented and well-structured review across the whole spectrum of hepatobiliary diseases by some of the world’s leading hepatologists and hepatobiliary specialists. Where many other hepatology textbooks provide detailed accounts of basic science and clinical management, Sherlock's Diseases of the Liver and Biliary System, 13th Edition takes a different approach. Concentrating on the clinical decisions to be taken and the relevant supporting data, it is written and edited to maintain Sheila Sherlock's unique approach, in particular the clarity and layout of the text, and the explanatory figures and tables. The book is thus concise, highly accessible, and generously illustrated with over 700 attractive color figures. There is a pithy approach to each disease based both on evidence and on the authors’ experience, the hallmark of this book. Based on these elements, the 12th edition was awarded first prize in the 2012 British Medical Association Book Awards in the Internal Medicine category. Sherlock's Diseases of the Liver and Biliary System begins by introducing the anatomy and function of the liver to readers, continuing then with in-depth coverage of liver biopsy techniques and interpretation, and fibrogenesis and its assessment. There are then chapters on all aspects of liver and biliary disease including acute liver failure, cirrhosis, portal hypertension, hepatic encephalopathy, ascites, hepatitis B and C, alcohol and the liver, non-alcoholic fatty liver disease, drug related liver reactions, cholestatic, autoimmune and genetic liver diseases, benign and malignant tumours and not least liver transplantation. There are also chapters on the liver in pregnancy, in the neonate, infancy and childhood, in systemic diseases and in infections. This new edition also features four new individual chapters focusing on coagulation, non-invasive assessment of fibrosis and cirrhosis; vascular diseases of the liver and portal vein thrombosis, and nutrition in liver disease. Digital downloads of the figures from this edition are offered on a companion website. Internationally recognized and loved, world-renowned hepatology book, first published in 1955 Takes a one-of-a-kind, clinical approach maintaining Sheila Sherlock’s clarity and legacy of presentation Full colour throughout with 700 illustrative figures Wide faculty of international contributors Sherlock's Diseases of the Liver and Biliary System, 13th Edition is an ideal primer in hepatology for students and trainees in hepatology and gastroenterology, and a valuable resource for all specialist gastroenterologists and hepatologists, paediatricians, pathologists, radiologists, general physicians and specialist nurses.
Book Synopsis Clinical Review of Oral and Maxillofacial Surgery by : Shahrokh C. Bagheri
Download or read book Clinical Review of Oral and Maxillofacial Surgery written by Shahrokh C. Bagheri and published by Mosby Incorporated. This book was released on 2008 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organized around real patient scenarios, Clinical Review of Oral and Maxillofacial Surgery: A Case-based Approach, 2nd Edition, covers all the material you need to know for the board, in-service, and certification exams, while also preparing you to handle common patient situations in professional practice. Over 100 teaching cases are brought to life with an overview of the most common clinical presentations, physical examination findings, diagnostic tools, complications, treatments, and discussions of possible issues. This text covers the full scope of modern oral and maxillofacial surgery, while helping you focus on the conditions and disorders which are the most common, or have significant implications for modern clinical practice. "I would most definitely recommend this book." Reviewed by: N.Galligan, British Dental Journal Date: Jan 2015 Case-based approach incorporates teaching around real patient scenarios to actively engage and raise your interest and retention of the information. 103 cases, many of which are new, represent the full scope of modern oral and maxillofacial surgery practice to encompass the most common and significant implications for modern clinical practice, including content emphasized on OMS boards and training exams. Detailed illustrations including one or more radiographs, full-color clinical photographs, or drawings for the majority of cases provide a visual guide to conditions, techniques, diagnoses, and key concepts that will further enhance your understanding and retention of all content. Content that's perfect for all levels of study or practice covers both concepts and techniques that residents and pre-doctoral students can apply in the clinical setting, and the preparation tools necessary for oral and maxillofacial surgery boards and training/certification examinations. NEW! Full-color illustrations and photos give you a better pictures of common surgical techniques and pathology. NEW! Chapter 6: Dental Implant Surgery discusses the contemporary issues related to dental implants - specifically the routine placement of maxillary and mandibular implants, sinus augmentation, zygoma implants, treatment of edentulism, guided implant surgery, extraction socket preservation, and implantology for the esthetic zone. NEW! Section on cone beam computed tomography (CBCT) highlights the role of imaging from diagnosis to image guidance for many surgical procedures. NEW! Section on the advantages of computer assisted surgery highlights virtual surgical planning for a patient who presents for combined surgical and orthodontic correction of his facial asymmetry and apertognathia. NEW! Section on trigeminal neuralgia (TN) walks you through the diagnosis and possible treatments for a patient suffering from trigeminal neuralgia, the signs and symptoms that uniquely define the disorder, and the clinician's ability to recognize the specific diagnostic pattern. NEW! Section on neck dissection, an important aspect of head and neck cancer treatment, provides a case that involves a patient in which right selective neck dissection (I-III) was conducted on the right neck and a selective left neck dissection (I-V) was completed on the left side. NEW! Section on dentoalveolar trauma presents a new case that takes you through diagnosing and treating a patient who presents with anterior maxillary alveolar segment fractures involving teeth #7-9, with lateral luxation and Ellis class III fracture tooth of #9, and an intraoral laceration of the upper lip. NEW! Section on nasal septoplasty addresses a patient with a severely deviated nasal septum to the left, involving the quadrangular cartilage and the bony septum and how septoplasty can make a dramatic change in the patient's quality of life, by facilitating nasal airflow, allowing for better spontaneous drainage of the paranasal sinuses, possibly reducing mouth breathing, and reducing or eliminating the symptoms of snoring, and perhaps lessening the severity of the obstructive sleep apnea syndrome.
Book Synopsis Adverse Cutaneous Drug Eruptions by : Lars E. French
Download or read book Adverse Cutaneous Drug Eruptions written by Lars E. French and published by Karger Medical and Scientific Publishers. This book was released on 2012 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: An indispensable tool for understanding, diagnosing and managing this common clinical problem The skin is one of the most frequently involved organs in adverse drug reactions. Occurring with an incidence of 1-5% for certain types of drugs, cutaneous drug eruptions are mostly benign in nature, and comprise the maculopapular type of eruption and urticaria. However, about one third of them require hospital treatment, leading to a considerable burden for the health care system. In this book, a selected group of experts provide an up-to-date, condensed and clinically relevant overview of the field of cutaneous drug eruptions, ranging from epidemiology and genetic predisposition to available therapeutic measures, including rapid drug desensitization. Reflecting the great progress made in recent years in this field, this publication will be a useful tool for a better understanding, diagnosis and management of cutaneous drug eruptions, not only for general physicians, dermatologists and clinical allergologists, but also for nurses and scientists.
Book Synopsis Mann's Pharmacovigilance by : Elizabeth B. Andrews
Download or read book Mann's Pharmacovigilance written by Elizabeth B. Andrews and published by John Wiley & Sons. This book was released on 2014-03-24 with total page 878 pages. Available in PDF, EPUB and Kindle. Book excerpt: Highly Commended at the BMA Medical Book Awards 2015 Mann’s Pharmacovigilance is the definitive reference for the science of detection, assessment, understanding and prevention of the adverse effects of medicines, including vaccines and biologics. Pharmacovigilance is increasingly important in improving drug safety for patients and reducing risk within the practice of pharmaceutical medicine. This new third edition covers the regulatory basis and the practice of pharmacovigilance and spontaneous adverse event reporting throughout the world. It examines signal detection and analysis, including the use of population-based databases and pharmacoepidemiological methodologies to proactively monitor for and assess safety signals. It includes chapters on drug safety practice in specific organ classes, special populations and special products, and new developments in the field. From an international team of expert editors and contributors, Mann’s Pharmacovigilance is a reference for everyone working within pharmaceutical companies, contract research organisations and medicine regulatory agencies, and for all researchers and students of pharmaceutical medicine. The book has been renamed in honor of Professor Ronald Mann, whose vision and leadership brought the first two editions into being, and who dedicated his long career to improving the safety and safe use of medicines.
Book Synopsis Side-Effects of Anti-Inflammatory Drugs by : K. D. Rainsford
Download or read book Side-Effects of Anti-Inflammatory Drugs written by K. D. Rainsford and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Liver written by Irwin M. Arias and published by John Wiley & Sons. This book was released on 2011-08-24 with total page 2022 pages. Available in PDF, EPUB and Kindle. Book excerpt: In its Fifth Edition, this classic book retains its traditional strength of relating molecular physiology to understanding disease pathology and treatment as it explores the current state and future direction of hepatology. Painstakingly revised, this edition includes 60 new chapters. As in previous editions, a section called Horizons summarizes advances of extraordinary nature in areas expected to have a substantial impact on hepatology. The Fifth Edition’s Horizons section includes emerging topics such as tissue engineering of the liver, liver-directed gene therapy, decoding the liver cancer genome, and imaging cellular proteins and structure. To preserve essential background information which has not changed while making room for the panoply of major new contributions to understanding of liver disease, 14 chapters from the previous edition are freely available online at gastrohep.com. To view these chapters visit - http://www.gastrohep.com/theliver/
Book Synopsis Inflammatory Mechanisms in Allergic Diseases by : Burton Zweiman
Download or read book Inflammatory Mechanisms in Allergic Diseases written by Burton Zweiman and published by CRC Press. This book was released on 2023-01-06 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contains patterns of allergic reactivity for disorders such as asthma, atopic dermatitis, urticaria, and anaphylaxis. Written by leading experts in the field, Inflammatory Mechanisms in Allergic Diseases covers non-anaphylactic drug disorders; synthesis and formation of IgE antibodies; new treatments using allergenic peptides, immunostimulatory oligonucleotides, and pharmacogenomics;recent advances targeting effector mechanisms; hypersensitivity reactions to drugs and more! With over 3100 references, tables, drawings, and micrographs, Inflammatory Mechanisms in Allergic Diseases is an essential reference for allergists, pulmonologists, immunologists, dermatologists, ophthalmologists, otolaryngologists, internists, pediatricians, family practitioners, and medical students in these disciplines.
Book Synopsis Adverse Drug Reactions by : Jack Uetrecht
Download or read book Adverse Drug Reactions written by Jack Uetrecht and published by Springer Science & Business Media. This book was released on 2009-12-18 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the current state of knowledge of basic mechanisms of adverse drug reactions (ADRs). The main focus is on idiosyncratic drug reactions because they are the most difficult to deal with. It starts with a general description of the major targets for ADRs followed by a description of what are presently believed to be mediators and biochemical pathways involved in idiosyncratic drug reactions. There is also a description of several examples of ADRs that serve to illustrate specific aspects of ADR mechanisms. Eventually the book shows that ultimately better methods are needed to predict which drug candidates are likely to cause ADRs and which patients are at increased risk. But at present research seems to be far from this goal.
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