In Vivo Inhalation Toxicity Screening Methods For Manufactured Nanomaterials

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In Vivo Inhalation Toxicity Screening Methods for Manufactured Nanomaterials

Author : Toru Takebayashi
Publisher : Springer Nature
ISBN 13 : 9811384339
Total Pages : 221 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis In Vivo Inhalation Toxicity Screening Methods for Manufactured Nanomaterials by : Toru Takebayashi

Download or read book In Vivo Inhalation Toxicity Screening Methods for Manufactured Nanomaterials written by Toru Takebayashi and published by Springer Nature. This book was released on 2019-08-20 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited volume discusses the short-term inhalation study (STIS) and intratracheal administration, the two major in vivo inhalation-toxicity screening methods, which play an important role in efficient hazard evaluation. It also provides a general overview of the inhalation toxicity of nanomaterials and related issues. For each screening method, it provides up-to-date information on the test procedures, interpretation of the test results, useful applications, and related technologies. In view of the increasing variety of nanomaterials in practical use, the book offers a basis for building a framework for grouping and read-across assessments of nanomaterials. With contributions by academic and industrial experts, In vivo Inhalation Toxicity Screening Methods for Manufactured Nanomaterials is a pragmatic reference resource for readers who are responsible for assessing the safety of nanomaterials in R&D and business, as well as researchers.

In Vivo Inhalation Toxicity Screening Methods for Manufactured Nanomaterials

Author :
Publisher :
ISBN 13 : 9789811384349
Total Pages : 221 pages
Book Rating : 4.3/5 (843 download)

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Book Synopsis In Vivo Inhalation Toxicity Screening Methods for Manufactured Nanomaterials by :

Download or read book In Vivo Inhalation Toxicity Screening Methods for Manufactured Nanomaterials written by and published by . This book was released on 2019 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited volume discusses the short-term inhalation study (STIS) and intratracheal administration, the two major in vivo inhalation-toxicity screening methods, which play an important role in efficient hazard evaluation. It also provides a general overview of the inhalation toxicity of nanomaterials and related issues. For each screening method, it provides up-to-date information on the test procedures, interpretation of the test results, useful applications, and related technologies. In view of the increasing variety of nanomaterials in practical use, the book offers a basis for building a framework for grouping and read-across assessments of nanomaterials. With contributions by academic and industrial experts, In vivo Inhalation Toxicity Screening Methods for Manufactured Nanomaterials is a pragmatic reference resource for readers who are responsible for assessing the safety of nanomaterials in R&D and business, as well as researchers.

Particle Toxicology

Author : Ken Donaldson
Publisher : CRC Press
ISBN 13 : 1420003143
Total Pages : 462 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Particle Toxicology by : Ken Donaldson

Download or read book Particle Toxicology written by Ken Donaldson and published by CRC Press. This book was released on 2006-12-21 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exposure to particles in industry and mining and from accidental anthropogenic sources constitutes an ongoing threat. Most recently nanoparticles arising from advances in technology are exposing a wider population to pathogenic stimuli. The effects of inhaled particles are no longer confined to the lung as nanoparticles have the potential to transl

Wildlife Toxicity Assessments for Chemicals of Military Concern

Author : Marc Williams
Publisher : Elsevier
ISBN 13 : 0128004800
Total Pages : 725 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Wildlife Toxicity Assessments for Chemicals of Military Concern by : Marc Williams

Download or read book Wildlife Toxicity Assessments for Chemicals of Military Concern written by Marc Williams and published by Elsevier. This book was released on 2015-05-21 with total page 725 pages. Available in PDF, EPUB and Kindle. Book excerpt: Wildlife Toxicity Assessments for Chemicals of Military Concern is a compendium of chemical-specific toxicity information with discussions on the rationale and development of Wildlife Toxicity Reference Values (TRVs) intended for use on terrestrial wildlife for risk assessment applications. Substances covered include military-related chemicals including explosives, propellants, pesticides and metals. Wildlife Toxicity Assessments for Chemicals of Military Concern is a much-needed resource designed to meet the needs of those seeking toxicological information for ecological risk assessment purposes. Each chapter targets a specific chemical and considers the current knowledge of the toxicological impacts of chemicals to terrestrial wildlife including mammalian, avian, amphibian and reptilian species. - Provides detailed information on how Wildlife Toxicity Values (TRVs) for military chemicals of concern are derived and evaluated. - Covers wildlife toxicity assessments of explosives, metals and environmental chemicals. - Compiles relevant information on the environmental effects of chemicals on wildlife in relation to public and environmental health.

Handbook of Nanotoxicology, Nanomedicine and Stem Cell Use in Toxicology

Author : Saura C. Sahu
Publisher : John Wiley & Sons
ISBN 13 : 1118855868
Total Pages : 713 pages
Book Rating : 4.1/5 (188 download)

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Book Synopsis Handbook of Nanotoxicology, Nanomedicine and Stem Cell Use in Toxicology by : Saura C. Sahu

Download or read book Handbook of Nanotoxicology, Nanomedicine and Stem Cell Use in Toxicology written by Saura C. Sahu and published by John Wiley & Sons. This book was released on 2014-04-22 with total page 713 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Nanotoxicology, Nanomedicine and Stem Cell Use in Toxicology provides an insight into the current trends and future directions of research in these rapidly developing scientific fields. Written by leading scientists and experts, the Handbook will be of interest to various scientific disciplines including toxicology, medicine, and pharmacology, as well as food, drug, and other regulatory sciences.

Emerging Nanotechnologies for Renewable Energy

Author : Waqar Ahmed
Publisher : Elsevier
ISBN 13 : 0128213574
Total Pages : 625 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Emerging Nanotechnologies for Renewable Energy by : Waqar Ahmed

Download or read book Emerging Nanotechnologies for Renewable Energy written by Waqar Ahmed and published by Elsevier. This book was released on 2021-02-16 with total page 625 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emerging Nanotechnologies for Renewable Energy offers a detailed overview of the benefits and applications of nanotechnology in the renewable energy sector. The book highlights recent work carried out on the emerging role of nanotechnology in renewable energy applications, ranging from photovoltaics, to battery technology and energy from waste. Written by international authors from both industry and academia, the book covers topics including scaling up from laboratory to industrial scale. It is a valuable resource for students at postgraduate and advanced undergraduate levels, researchers in industry and academia, technology leaders, and policy and decision-makers in the energy and engineering sectors. - Offers insights into a wide range of nanoscale technologies for the generation, storage and transfer of energy - Shows how nanotechnology is being used to create new, more environmentally friendly energy solutions - Assesses the challenges involved in scaling up nanotechnology-based energy solutions to an industrial scale

Toxicity Testing in the 21st Century

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309109922
Total Pages : 217 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Toxicity Testing in the 21st Century by : National Research Council

Download or read book Toxicity Testing in the 21st Century written by National Research Council and published by National Academies Press. This book was released on 2007-10-05 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in molecular biology and toxicology are paving the way for major improvements in the evaluation of the hazards posed by the large number of chemicals found at low levels in the environment. The National Research Council was asked by the U.S. Environmental Protection Agency to review the state of the science and create a far-reaching vision for the future of toxicity testing. The book finds that developing, improving, and validating new laboratory tools based on recent scientific advances could significantly improve our ability to understand the hazards and risks posed by chemicals. This new knowledge would lead to much more informed environmental regulations and dramatically reduce the need for animal testing because the new tests would be based on human cells and cell components. Substantial scientific efforts and resources will be required to leverage these new technologies to realize the vision, but the result will be a more efficient, informative and less costly system for assessing the hazards posed by industrial chemicals and pesticides.

Synchrotron Radiation in Materials Science

Author : Chunhai Fan
Publisher : John Wiley & Sons
ISBN 13 : 3527339868
Total Pages : 846 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Synchrotron Radiation in Materials Science by : Chunhai Fan

Download or read book Synchrotron Radiation in Materials Science written by Chunhai Fan and published by John Wiley & Sons. This book was released on 2018-05-29 with total page 846 pages. Available in PDF, EPUB and Kindle. Book excerpt: Meeting the long-felt need for in-depth information on one of the most advanced material characterization methods, a top team of editors and authors from highly prestigious facilities and institutions covers a range of synchrotron techniques that have proven useful for materials research. Following an introduction to synchrotron radiation and its sources, the second part goes on to describe the various techniques that benefit from this especially bright light, including X-ray absorption, diffraction, scattering, imaging, and lithography. The thrid and final part provides an overview of the applications of synchrotron radiation in materials science. bridging the gap between specialists in synchrotron research and material scientists, this is a unique and indispensable resource for academic and industrial researchers alike.

Toxicity of Nanomaterials

Author : Suresh C. Pillai
Publisher :
ISBN 13 : 9780429265471
Total Pages : 0 pages
Book Rating : 4.2/5 (654 download)

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Book Synopsis Toxicity of Nanomaterials by : Suresh C. Pillai

Download or read book Toxicity of Nanomaterials written by Suresh C. Pillai and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Choice Recommended Title, April 2020 This comprehensive book, edited by two leading experts in nanotechnology and bioengineering with contributions from a global team of specialists, provides a detailed overview of the environmental and health impacts associated with the toxicology of nanomaterials. Special attention is given to nanomaterial toxicity during synthesis, production and application, and chapters throughout are focused on key areas that are important for future research and development of nanomaterials. This book will be of interest to advanced students studying biomedical engineering and materials science, PhD researchers, post-docs and academics working in the area of nanotechnology, medicine, manufacturing and regulatory bodies. Features: Collates and critically evaluates various aspects of the toxicology of nanomaterials in one comprehensive text Discusses the various effects of nanocrystals including the morphologies on cytotoxicity, in addition to the environmental and cytotoxicity risks of graphene and 2D nanomaterials Explores practical methods of detection and quantification, with applications in the environmental and healthcare fields

Computational Nanotoxicology

Author : Agnieszka Gajewicz
Publisher : CRC Press
ISBN 13 : 1000681424
Total Pages : 307 pages
Book Rating : 4.0/5 (6 download)

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Book Synopsis Computational Nanotoxicology by : Agnieszka Gajewicz

Download or read book Computational Nanotoxicology written by Agnieszka Gajewicz and published by CRC Press. This book was released on 2019-11-13 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of computational methods that support human health and environmental risk assessment of engineered nanomaterials has attracted great interest because the application of these methods enables us to fill existing experimental data gaps. However, considering the high degree of complexity and multifunctionality of engineered nanoparticles, computational methods originally developed for regular (i.e., classic) chemicals cannot always be applied explicitly in nanotoxicology. Thus, the main idea of this book is to discuss the current state of the art and future needs in the development of computational modeling techniques for nanotoxicology. The book focuses on methodology. Among various in silico techniques, special attention is given to (i) computational chemistry (quantum mechanics, semi-empirical methods, density functional theory, molecular mechanics, molecular dynamics); (ii) nanochemoinformatic methods (quantitative structure–activity relationship modeling, grouping, read-across); and (iii) nanobioinformatic methods (genomics, transcriptomics, proteomics, metabolomics).

Marine Anthropogenic Litter

Author : Melanie Bergmann
Publisher : Springer
ISBN 13 : 3319165100
Total Pages : 456 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Marine Anthropogenic Litter by : Melanie Bergmann

Download or read book Marine Anthropogenic Litter written by Melanie Bergmann and published by Springer. This book was released on 2015-06-01 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes how man-made litter, primarily plastic, has spread into the remotest parts of the oceans and covers all aspects of this pollution problem from the impacts on wildlife and human health to socio-economic and political issues. Marine litter is a prime threat to marine wildlife, habitats and food webs worldwide. The book illustrates how advanced technologies from deep-sea research, microbiology and mathematic modelling as well as classic beach litter counts by volunteers contributed to the broad awareness of marine litter as a problem of global significance. The authors summarise more than five decades of marine litter research, which receives growing attention after the recent discovery of great oceanic garbage patches and the ubiquity of microscopic plastic particles in marine organisms and habitats. In 16 chapters, authors from all over the world have created a universal view on the diverse field of marine litter pollution, the biological impacts, dedicated research activities, and the various national and international legislative efforts to combat this environmental problem. They recommend future research directions necessary for a comprehensive understanding of this environmental issue and the development of efficient management strategies. This book addresses scientists, and it provides a solid knowledge base for policy makers, NGOs, and the broader public.

OECD Guidelines for the Testing of Chemicals, Section 4: Health Effects Test No. 436: Acute Inhalation Toxicity – Acute Toxic Class Method

Author : OECD
Publisher : OECD Publishing
ISBN 13 : 9264076034
Total Pages : 27 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4: Health Effects Test No. 436: Acute Inhalation Toxicity – Acute Toxic Class Method by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4: Health Effects Test No. 436: Acute Inhalation Toxicity – Acute Toxic Class Method written by OECD and published by OECD Publishing. This book was released on 2009-09-08 with total page 27 pages. Available in PDF, EPUB and Kindle. Book excerpt: The method described by this Test Guideline provides information that allows hazard assessment for short-term exposure to a test article by inhalation, and allows the substance to be classified according to the Globally Harmonized System of ...

The ELSI Handbook of Nanotechnology

Author : Chaudhery Mustansar Hussain
Publisher : John Wiley & Sons
ISBN 13 : 1119592968
Total Pages : 597 pages
Book Rating : 4.1/5 (195 download)

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Book Synopsis The ELSI Handbook of Nanotechnology by : Chaudhery Mustansar Hussain

Download or read book The ELSI Handbook of Nanotechnology written by Chaudhery Mustansar Hussain and published by John Wiley & Sons. This book was released on 2020-03-31 with total page 597 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Handbook focuses on the recent advancements in Safety, Risk, Ethical Society and Legal Implications (ESLI) as well as its commercialization of nanotechnology, such as manufacturing. Nano is moving out of its relaxation phase of scientific route, and as new products go to market, organizations all over the world, as well as the general public, are discussing the environmental and health issues associated with nanotechnology. Nongovernmental science organizations have long since reacted; however, now the social sciences have begun to study the cultural portent of nanotechnology. Societal concerns and their newly constructed concepts, show nanoscience interconnected with the economy, ecology, health, and governance. This handbook addresses these new challenges and is divided into 7 sections: Nanomaterials and the Environment; Life Cycle Environmental Implications of Nanomanufacturing; Bioavailability and Toxicity of Manufactured Nanoparticles in Terrestrial Environments; Occupational Health Hazards of Nanoparticles; Ethical Issues in Nanotechnology; Commercialization of Nanotechnology; Legalization of Nanotechnology.

Nanotoxicology

Author : Nancy A. Monteiro-Riviere
Publisher : CRC Press
ISBN 13 : 1482203871
Total Pages : 516 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Nanotoxicology by : Nancy A. Monteiro-Riviere

Download or read book Nanotoxicology written by Nancy A. Monteiro-Riviere and published by CRC Press. This book was released on 2014-03-03 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the first publication of this book in 2007, the field of nanoscience and nanomedicine continues to grow substantially. This second edition, Nanotoxicology: Progress toward Nanomedicine, enlists internationally recognized experts to document the continuing development and rationale for the safe design of engineered nanomaterials (ENM). This includes new improved characterization endpoints, screening, and detection methods for in vitro and in vivo toxicity testing. These tools also contribute greatly to nanosafety research applied to nanomedicines. Topics include The impacts of nanotechnology on biomedicine, including functionalization for tissue-specific targeting, the biointeractions of multifunctional nanoparticle-based therapy, and the ability to control specific physicochemical properties of nanoparticles The requirements for proper detection, measurement, and assessment both for workplace exposure and in consumer products—with a focus on potential health and safety implications Predictive modeling, using quantitative nanostructure activity relationships to predict the pharmacokinetics and biodistribution of nanomaterials in the body Specific methodologies, imaging, and techniques to assess nanomaterials from the manufacturing process to nanomedicine applications Tools for assessing nanoparticle toxicity and the limitations of detection methods for assessing toxicity in both in vivo and in vitro systems and at the single cell and tissue levels Toxicity of nanomaterials to specific organ systems, cell–based targeting to tumors, and other biomedical applications The difficulty of conducting risk assessments and the need for addressing knowledge gaps, especially with long-term studies A roadmap for future research The development of nanotechnology-based products must be complemented with appropriate validated methods to assess, monitor, manage, and reduce the potential risks of ENM to human health and the environment. This volume provides a cogent survey of advances in this area by a well-respected and diverse group of international scientists.

Comprehensive Toxicology

Author :
Publisher : Elsevier
ISBN 13 : 0081006128
Total Pages : 8639 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Comprehensive Toxicology by :

Download or read book Comprehensive Toxicology written by and published by Elsevier. This book was released on 2017-12-01 with total page 8639 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Toxicology, Third Edition, Fifteen Volume Set discusses chemical effects on biological systems, with a focus on understanding the mechanisms by which chemicals induce adverse health effects. Organized by organ system, this comprehensive reference work addresses the toxicological effects of chemicals on the immune system, the hematopoietic system, cardiovascular system, respiratory system, hepatic toxicology, renal toxicology, gastrointestinal toxicology, reproductive and endocrine toxicology, neuro and behavioral toxicology, developmental toxicology and carcinogenesis, also including critical sections that cover the general principles of toxicology, cellular and molecular toxicology, biotransformation and toxicology testing and evaluation. Each section is examined in state-of-the-art chapters written by domain experts, providing key information to support the investigations of researchers across the medical, veterinary, food, environment and chemical research industries, and national and international regulatory agencies. Thoroughly revised and expanded to 15 volumes that include the latest advances in research, and uniquely organized by organ system for ease of reference and diagnosis, this new edition is an essential reference for researchers of toxicology. Organized to cover both the fundamental principles of toxicology and unique aspects of major organ systems Thoroughly revised to include the latest advances in the toxicological effects of chemicals on the immune system Features additional coverage throughout and a new volume on toxicology of the hematopoietic system Presents in-depth, comprehensive coverage from an international author base of domain experts

Engineered Nanoparticles and the Environment

Author : Baoshan Xing
Publisher : John Wiley & Sons
ISBN 13 : 1119275830
Total Pages : 510 pages
Book Rating : 4.1/5 (192 download)

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Book Synopsis Engineered Nanoparticles and the Environment by : Baoshan Xing

Download or read book Engineered Nanoparticles and the Environment written by Baoshan Xing and published by John Wiley & Sons. This book was released on 2016-08-29 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: Details the source, release, exposure, adsorption, aggregation, bioavailability, transport, transformation, and modeling of engineered nanoparticles found in many common products and applications Covers synthesis, environmental application, detection, and characterization of engineered nanoparticles Details the toxicity and risk assessment of engineered nanoparticles Includes topics on the transport, transformation, and modeling of engineered nanoparticles Presents the latest developments and knowledge of engineered nanoparticles Written by world leading experts from prestigious universities and companies

Handbook of Safety Assessment of Nanomaterials

Author : Bengt Fadeel
Publisher : CRC Press
ISBN 13 : 9814463361
Total Pages : 565 pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis Handbook of Safety Assessment of Nanomaterials by : Bengt Fadeel

Download or read book Handbook of Safety Assessment of Nanomaterials written by Bengt Fadeel and published by CRC Press. This book was released on 2014-12-10 with total page 565 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rapidly evolving field of nanomedicine refers to the clinical application of nanotechnologies. However, as with all new technologies, there are ethical, safety, and regulatory issues. This handbook, written by leading international experts, provides a meticulous overview of the state of the art of safety assessment of nanomaterials (nanotoxicology) in the context of their application in nanomedicine. The volume includes a historical perspective on the development of nanomedicine and its regulation, and a personal view of the future of (nano)medicine by Patrick Hunziker, president of the European Society of Nanomedicine. Ethical considerations in relation to nanomedicine are discussed. There are a series of chapters on organ-specific toxicities of nanomaterials, including pulmonary and cardiovascular toxicity, neurotoxicity, dermatotoxicity, and reproductive toxicity, as well as a discussion on immunotoxicity and genotoxicity. The importance of a thorough characterization of physicochemical properties of nanomaterials is emphasized. The handbook also contains a critical discussion on the applicability of in vitro versus in vivo methods and models for nanosafety assessment, along with an introduction to mathematical modeling approaches with a view to a predictive toxicology of nanomaterials. The overall aim is to provide a comprehensive, science-based framework for safety assessment of current and future nanomedicines.