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Author :
Publisher :
ISBN 13 :
Total Pages : 6 pages
Book Rating : 4.:/5 (174 download)
Download or read book In Vivo Diagnosis and Therapy of Human Tumors with Monoclonal Antibodies written by and published by . This book was released on 1989 with total page 6 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book In Vivo Diagnosis and Therapy of Human Tumors with Monoclonal Antibodies. Pt. 1 written by and published by . This book was released on 1989 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book In Vivo Diagnosis and Therapy of Human Tumors with Monoclonal Antibodies written by and published by . This book was released on 1989 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : W.C. Eckelman
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (841 download)
Download or read book In Vivo Diagnosis and Therapy of Human Tumors with Monoclonal Antibodies. Pt. 2. Proceedings of a Symposium Held in Napels, Italy, 16-19 March 1988 written by W.C. Eckelman and published by . This book was released on 1989 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : William C. Eckelman
Publisher :
ISBN 13 :
Total Pages : 8 pages
Book Rating : 4.:/5 (18 download)
Download or read book In Vivo Diagnosis and Therapy of Human Tumors with Monoclonal Antibodies written by William C. Eckelman and published by . This book was released on 1989 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Suresh C. Srivastava
Publisher : Springer Science & Business Media
ISBN 13 : 1468455389
Total Pages : 851 pages
Book Rating : 4.4/5 (684 download)
Download or read book Radiolabeled Monoclonal Antibodies for Imaging and Therapy written by Suresh C. Srivastava and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 851 pages. Available in PDF, EPUB and Kindle. Book excerpt: The advent of hybridoma technology leading to the successful produc tion of monoclonal antibodies against a variety of tumor-associated antigens has, during the last decade, provided a very powerful tool for research and clinical investigations. These highly specific reagents have essentially replaced the polysera of the earlier days. The successful demonstration of the many wide ranging capabilities of the monoclonal antibody technique has already begun to exert an enormous impact on diverse areas of research in basic science and medicine. In particular, the potential of monoclonal antibodies to serve as carriers for selective targeting of radionuclides to tumors for diagnosis or therapy, has stimulated an intense surge of research interest and even revived hopes of realizing Ehrlich's concept of the "magic bullet". Indeed, the technology appears to be on the threshold of a revolution in diagnosing and treating malignant disease. Much work remains to be done, however, and even though the progress has been impressive, results to date have shown only moderate success. There is no question that the limited success we have achieved thus far is merely a prelude to the many more exciting developments yet to come.
Author :
Publisher :
ISBN 13 :
Total Pages : 268 pages
Book Rating : 4.3/5 (91 download)
Download or read book Symposium on Monoclonal Antibodies for Therapy, Prevention, and in Vivo Diagnosis of Human Disease written by and published by . This book was released on 1990 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kenneth A. Foon
Publisher : Springer Science & Business Media
ISBN 13 : 1461326273
Total Pages : 171 pages
Book Rating : 4.4/5 (613 download)
Download or read book Monoclonal Antibody Therapy of Human Cancer written by Kenneth A. Foon and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 171 pages. Available in PDF, EPUB and Kindle. Book excerpt: KENNETH A. FOON and ALTON C. MORGAN, JR. Passive immunotherapy using heteroantisera for the treatment of cancer in animals and humans has been studied for over 50 years. Attempts have been made to treat animal tumors with sera from immunized syngeneic, allogeneic, or xenogeneic animals. A number of studies of passive immunotherapy using heterologous antisera in humans have also been performed. These studies have generally been attempted in patients with large tumor burdens, and as would be expected, results have been transient at best. A wide variety of solid tumors as well as leukemias and lym phomas have been treated with antisera raised in sheep, horses, rabbits, and goats. Problems such as anaphylaxis, serum sick ness, and severe cytopenias have been encountered with these antisera. There are a number of potential mechanisms by which unconju gated antibodies might be cytotoxic to tumor cells. Antibodies bound to the cell surface membrane of tumor cells may lead to cell lysis by complement-dependent or antibody-dependent cellu lar cytotoxicity. Circulating tumor cells bound by antibody may be more susceptible to phagocytosis by the reticuloendothelial system. Antibody bound to the cell surface membrane of tumor cells may enhance immunogenicity of the tumor cell leading to activation of the host's immune system.
Author : Jack A. Roth
Publisher : Blackwell/Futura
ISBN 13 :
Total Pages : 360 pages
Book Rating : 4.3/5 (91 download)
Download or read book Monoclonal Antibodies in Cancer written by Jack A. Roth and published by Blackwell/Futura. This book was released on 1986 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 196 pages
Book Rating : 4.:/5 (319 download)
Download or read book International Symposium on Labeled and Unlabeled Antibody in Cancer Diagnosis and Therapy written by and published by . This book was released on 1987 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Ralph A. Reisfeld
Publisher :
ISBN 13 :
Total Pages : 640 pages
Book Rating : 4.:/5 (45 download)
Download or read book Monoclonal Antibodies and Cancer Therapy written by Ralph A. Reisfeld and published by . This book was released on 1985 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : R. Ceriani
Publisher : Springer Science & Business Media
ISBN 13 : 1461326176
Total Pages : 327 pages
Book Rating : 4.4/5 (613 download)
Download or read book Monoclonal Antibodies and Breast Cancer written by R. Ceriani and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: Breast cancer, being a disease with very high prevalence in the female population, has permanently attracted the attention of biologists, biochemists, pathologists, surgeons, and oncologists. In the U.S. alone approximately 120,000 new cases are diagnosed and 37,000 deaths a year are recorded as an outcome. Early diagnosis, clear cut prognosis and the hope of new therapeutic approaches has spurred the enthusiasm of researchers, who with the advent of newer methodologies, tried to employ it in different approaches to the breast cancer patient. In spite of the efforts devoted towards the creation of new approaches, reagents and procedures taking advantage of special characteristics of the breast tissue were slow to come. In general, most diagnostic and prognostic techniques were those shared and applied to other carcinomas. In the early seventies we discovered the first sets of antigens associated with breast epithelial tissue both in the mouse and the human. The recognition of such group of molecules, present in the milk fat globule membrane, gave impetus to several studies in these areas. These mammary cell surface antigens proved useful in several diagnostic approaches such as radioimaging, histochemical and serum assay procedures. However, the apparently inherent limitations of polyclonal antibodies reduced the impact of these novel approaches.
Author : Herbert Z. Kupchik
Publisher : Marcel Dekker
ISBN 13 :
Total Pages : 354 pages
Book Rating : 4.3/5 (91 download)
Download or read book Cancer Diagnosis in Vitro Using Monoclonal Antibodies written by Herbert Z. Kupchik and published by Marcel Dekker. This book was released on 1988 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Michael Magerstadt
Publisher : CRC Press
ISBN 13 : 9780849360893
Total Pages : 246 pages
Book Rating : 4.3/5 (68 download)
Download or read book Conjugates and Malignant Disease written by Michael Magerstadt and published by CRC Press. This book was released on 1991-01-03 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of antibody conjugates for in vivo applications. It discusses each of the major classes of antibody conjugates used in cancer diagnosis and therapy, as well as the major chemical and biological aspects of antibody selection, conjugate preparation, characterization, and application. The book is designed to close the information gap that exists regarding these compounds between such diverse disciplines as radiochemists, immunochemists, oncologists, clinicians and immunologists. It also provides a thorough overview for newcomers to the field.
Author : Prevention and In Vivo Diagnosis of Human Disease (1989: Utrecht Symposium on Monoclonal Antibodies for Therapy (the Netherlands))
Publisher :
ISBN 13 :
Total Pages : 246 pages
Book Rating : 4.:/5 (78 download)
Download or read book Symposium on Monoclonal Antibodies for Therapy, Prevention and in Vivo Diagnosis of Human Disease written by Prevention and In Vivo Diagnosis of Human Disease (1989: Utrecht Symposium on Monoclonal Antibodies for Therapy (the Netherlands)) and published by . This book was released on 1989 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Silvio Folli
Publisher :
ISBN 13 :
Total Pages : 244 pages
Book Rating : 4.:/5 (715 download)
Download or read book Monoclonal Antibodies for in Vivo Tumor Diagnosis and Therapy written by Silvio Folli and published by . This book was released on 1992 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309173051
Total Pages : 74 pages
Book Rating : 4.3/5 (91 download)
Download or read book Monoclonal Antibody Production written by National Research Council and published by National Academies Press. This book was released on 1999-05-06 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt: The American Anti-Vivisection Society (AAVS) petitioned the National Institutes of Health (NIH) on April 23, 1997, to prohibit the use of animals in the production of mAb. On September 18, 1997, NIH declined to prohibit the use of mice in mAb production, stating that "the ascites method of mAb production is scientifically appropriate for some research projects and cannot be replaced." On March 26, 1998, AAVS submitted a second petition, stating that "NIH failed to provide valid scientific reasons for not supporting a proposed ban." The office of the NIH director asked the National Research Council to conduct a study of methods of producing mAb. In response to that request, the Research Council appointed the Committee on Methods of Producing Monoclonal Antibodies, to act on behalf of the Institute for Laboratory Animal Research of the Commission on Life Sciences, to conduct the study. The 11 expert members of the committee had extensive experience in biomedical research, laboratory animal medicine, animal welfare, pain research, and patient advocacy (Appendix B). The committee was asked to determine whether there was a scientific necessity for the mouse ascites method; if so, whether the method caused pain or distress; and, if so, what could be done to minimize the pain or distress. The committee was also asked to comment on available in vitro methods; to suggest what acceptable scientific rationale, if any, there was for using the mouse ascites method; and to identify regulatory requirements for the continued use of the mouse ascites method. The committee held an open data-gathering meeting during which its members summarized data bearing on those questions. A 1-day workshop (Appendix A) was attended by 34 participants, 14 of whom made formal presentations. A second meeting was held to finalize the report. The present report was written on the basis of information in the literature and information presented at the meeting and the workshop.
