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Immunology Of Vitiligo
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Book Synopsis Immunology of Vitiligo by : Katia Boniface
Download or read book Immunology of Vitiligo written by Katia Boniface and published by Frontiers Media SA. This book was released on 2021-08-25 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Topic Editor Prof. John E. Harris is Scientific Founder of Villaris Therapeutics, Inc. Topic Editor Prof. Julien Seneschal received financial support from Sanofi Genzyme and Calypso Biotech. Topic Editor Prof. Caroline Le Poole is the CSO for Temprian Therapeutics, a company hoping to bring an HSP70iQ435A-based treatment to clinical trials for vitiligo. The approach for this treatment is different and separate from the proposed Research Topic. Please note that studies investigating HSP70iQ435A-based treatment thus fall out of the remit of this project. All other Topic Editors declare no competing interests with regards to the Research Topic subject.
Book Synopsis Clinical and Basic Immunodermatology by : Anthony Gaspari
Download or read book Clinical and Basic Immunodermatology written by Anthony Gaspari and published by Springer Science & Business Media. This book was released on 2008-11-05 with total page 812 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dermatologists are being asked to understand the pathophysiology of a number of immune-mediated skin diseases. In addition, a number of new products have appeared on the market during the past decade which requires an understanding of the mechanisms of action of these drugs. Dermatologists, however, have no easily understood book to which they can refer to regarding the disease or the drug.
Author :Brian J. Nickoloff Publisher :Karger Medical and Scientific Publishers ISBN 13 :3805583915 Total Pages :391 pages Book Rating :4.8/5 (55 download)
Book Synopsis Dermatologic Immunity by : Brian J. Nickoloff
Download or read book Dermatologic Immunity written by Brian J. Nickoloff and published by Karger Medical and Scientific Publishers. This book was released on 2008-01-01 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nickeloff (skin cancer research, Cardinal Bernardin Cancer Center, Chicago) and Nestle (cutaneous medicine and immunotherapy, King's College, London School of Medicine at Guy's, UK) assemble 19 review articles on autoimmune disease processes that affect the skin, covering both humoral and cellular immunity. The etiology, cellular and molecular mechanisms, therapeutic strategies, and pathophysiology of diseases such as psoriasis, dermatitis, cutaneous lupus erythematosus, vitiligo, and scleroderma are discussed by individuals in dermatology, genetics, immunology, and pathology who are based around the world. The book is aimed at clinical researchers, students, allergists, immunologists, dermatologists, and internists.
Book Synopsis Dermatology in Public Health Environments by : Renan Rangel Bonamigo
Download or read book Dermatology in Public Health Environments written by Renan Rangel Bonamigo and published by Springer. This book was released on 2018-01-26 with total page 1581 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a reference guide in the field of dermatology, presenting and discussing its interface with public health. Dermatological diseases are extremely common in populations around the globe, and the systematization of knowledge about these dermatoses and their relationships with different epidemiological factors may help us to understand the challenges that governments and private institutions face and must try to overcome in order to improve global health. Undergraduate and graduate students, dermatologists and general practitioners who study and / or work in the area will find scientific support in this book, which is intended as a reference work for dermatological practice and public health. The book has ten sections addressing carefully selected topics, including: 1. concepts in dermatoepidemiology and the international strategies in programs of Public Health; 2-6. the most significant skin diseases (including dermatology in tropical medicine) ; 7. diseases that are not primarily dermatological, but have a high impact on public health and may have skin and mucosal manifestations; 8. a number of emerging issues in dermatology in public health; 9. clinical approaches (diagnosis and management) to common dermatological symptoms and 10. multidisciplinary approaches in dermatology. The editors have brought together authors with extensive experience in their respective fields in order to provide a reference book for those involved in or with an interest in the relationship between dermatology and public health.
Download or read book Vitiligo written by Mauro Picardo and published by Springer. This book was released on 2019-07-23 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the first edition of this book was published, new knowledge has been gained on Vitiligo. This widely revised and updated second edition, written by worldwide experts in the field, fully reflects this progress. The apparently, simple and poorly symptomatic presentation of the disease has been a strong disadvantage to its study, as compared to other common chronic skin disorders such as psoriasis and atopic dermatitis. A good skin-based angle of attack is also lacking because generalized Vitiligo is clearly epitomizing the view of skin diseases as simple targets of a systemic unknown dysregulation (diathesis). This view has mostly restricted Vitiligo to the manifestation of an auto-immune diathesis and skin events, which are easily detected using skin biopsies in most other situations, have not been precisely recorded, with the argument that a clinical diagnosis was sufficient for the management of the patient with Vitiligo. This richly illustrated second edition reflects the constant international effort to share the information gathered about this disorder at the clinical, pathophysiological and therapeutic levels. Its aim still being to bridge current knowledge at the clinical and investigative level, to point to the many unsolved issues, and to delineate future priorities for research.
Download or read book Avian Immunology written by Bernd Kaspers and published by Academic Press. This book was released on 2012-12-02 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Avian Immunology provides an up-to-date overview of the current knowledge of avian immunology. From the ontogeny of the avian immune system to practical application in vaccinology, the book encompasses all aspects of innate and adaptive immunity in chickens. In addition, chapters are devoted to the immunology of other commercially important species such as turkeys and ducks, and to ecoimmunology summarizing the knowledge of immune responses in free-living birds often in relation to reproductive success. The book contains a detailed description of the avian innate immune system, encompassing the mucosal, enteric, respiratory and reproductive systems. The diseases and disorders it covers include immunodepressive diseases and immune evasion, autoimmune diseases, and tumors of the immune system. Practical aspects of vaccination are examined as well. Extensive appendices summarize resources for scientists including cell lines, inbred chicken lines, cytokines, chemokines, and monoclonal antibodies. The world-wide importance of poultry protein for the human diet, as well as the threat of avian influenza pandemics like H5N1 and heavy reliance on vaccination to protect commercial flocks makes this book a vital resource. This book provides crucial information not only for poultry health professionals and avian biologists, but also for comparative and veterinary immunologists, graduate students and veterinary students with an interest in avian immunology. With contributions from 33 of the foremost international experts in the field, this book provides the most up-to-date review of avian immunology so far Contains a detailed description of the avian innate immune system reviewing constitutive barriers, chemical and cellular responses; it includes a comprehensive review of avian Toll-like receptors Contains a wide-ranging review of the "ecoimmunology" of free-living avian species, as applied to studies of population dynamics, and reviews methods and resources available for carrying out such research
Book Synopsis Handbook of Vitiligo by : Iltefat Hamzavi
Download or read book Handbook of Vitiligo written by Iltefat Hamzavi and published by JP Medical Ltd. This book was released on 2015-11-10 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vitiligo is a chronic auto-immune disorder where permanent white patches appear on the skin and sometimes hair. It is most noticeable in skin of colour; it can be extensive, disfiguring and highly stigmatising in some cultures. For years there have been few truly effective treatments, but recent breakthroughs in the surgical treatment of the disease offer new options to clinicians, and hope to patients. Led by one of the foremost vitiligo educators and researchers into melanocyte transfer in the USA, Dr Iltefat Hamzavi, the author team has assembled this highly practical and clinical textbook for dermatologists and dermatologic surgeons. Handbook of Vitiligo: Basic Science and Clinical Management discusses all the latest management options available, from pharmacologic therapies (topical and systemic) to phototherapy and surgical procedures (including melanocyte-rich tissue grafts and autologous melanocyte suspension transplants). With contributions from a global team of experts, Handbook of Vitiligo offers a practical, clinically oriented overview to help clinicians choose the most effective treatment options for their patients. Summarises latest thinking on established therapies and emerging techniques Features practical, template-style text and emphasis on clinical application of techniques (not research data) Written by the key international names in the area
Book Synopsis Vitiligo and Other Hypomelanoses of Hair and Skin by : Jean-Paul Ortonne
Download or read book Vitiligo and Other Hypomelanoses of Hair and Skin written by Jean-Paul Ortonne and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 774 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leukoderma is a generic term for any pigmentary dilution, be it congenital or acquired, circumscribed or generalized, devoid of or partially lacking in pig mentation. In the approach to the diagnosis of leukoderma, we have generally first considered the age of onset, whether leukoderma was congenital or ac quired, the extent and pattern of involvement, and the degree of pigmentary dilution. The organization of this monograph reflects this approach. For ex ample, we have separated the section devoted to various disease entities into diffuse and circumscribed leukoderma and the latter into various etiologies such as genetic, metabolic, infectious, and endocrinologic. One of several justifications for this monograph is to present an approach to the diagnosis of leukoderma, as detailed in Part II. In formulating a guide for the physician, we have found some limitations to our previous approach; we therefore offer the following new classification based upon a clini cal-pathologic correlation. This could provide the means to describe both the clinical and pathologic findings in one term.
Book Synopsis Vitiligo: New Insights for the Healthcare Professional: 2012 Edition by :
Download or read book Vitiligo: New Insights for the Healthcare Professional: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-10 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vitiligo: New Insights for the Healthcare Professional / 2012 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Vitiligo in a compact format. The editors have built Vitiligo: New Insights for the Healthcare Professional / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Vitiligo in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Vitiligo: New Insights for the Healthcare Professional / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Book Synopsis Surgical Management of Vitiligo by : Somesh Gupta
Download or read book Surgical Management of Vitiligo written by Somesh Gupta and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although vitiligo has traditionally been very difficult to treat, anew breakthrough surgical treatment is expanding options forpractitioners and patients. Standard treatments depend on the severity of the condition andthe patient's feelings of disfigurement. Cover-up cosmetics workwell for some people. Other more sophisticated forms of treatmentinclude gradually developing color back in the depigmented areas(repigmentation) by PUVA or other ultraviolet light treatments, butthis is extremely slow and intensive, often requiring severalhundred treatments. This new form of treatment, which involves surgicallytransplanting melanocytes into the white areas, is most successfulin patients with stable vitiligo over less than 30% of their bodysurface area. It complements medical therapies in achievingcomplete and sustained repigmentation and is rapidly gainingpopularity in all major centers. This is the first book available which describes this majoradvance in detail. Explains the new treatment of surgically transplantingmelanocytes into the affected areas of the skin to providedermatologists and surgeons with the latest state-of-the-artinformation Written by the international leaders who pioneered thistreatment Presents all the latest information on the topic, eliminatingthe need to search through multiple sources for specific data
Book Synopsis Skin Immune System (SIS) by : Jan D. Bos
Download or read book Skin Immune System (SIS) written by Jan D. Bos and published by CRC Press. This book was released on 1997-04-10 with total page 768 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunodermatology is a field covering the majority of skin diseases, including the most prevalent onesin the general population. The Second Edition of Skin Immune System (SIS) discusses immune-mediated skin diseases and disease groups in which the SIS plays a role. It covers major findings in immunophysiology and immunopathology that have occurred since the introduction of the First Edition in 1990. As the subtitle indicates, the Second Edition adds a new emphasis on cutaneous immunology, and also includes new information on immune-based therapeutic interventions and methods, such as phototherapy and the immunological therapy of skin cancer. The book contains Part I, with introductory chapters; Part II, with descriptions of the cellular elements; and Part III, which describes the humoral and molecular components of SIS. Part IV follows to integrate the facts described in Parts II and III into concepts of pathophysiology. It contains a number of concepts entitled "response patterns" that describe how the constitutional elements of SIS work together. New in this edition are the descriptions of immunodermatological diseases individually described in Part V. Part VI is also all new and summarizes principles of immunotherapy.
Download or read book Vitiligo written by Mauro Picardo and published by Springer Science & Business Media. This book was released on 2010-03-26 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vitiligo has been, until recently, a rather neglected area in dermatology and medicine. Patients complain about this situation, which has offered avenues to quacks, and has led to the near orphan status of the disease. The apparently, simple and poorly symptomatic presentation of the disease has been a strong disadvantage to its study, as compared to other common chronic skin disorders such as psoriasis and atopic dermatitis. Vitiligo is still considered by doctors as a non disease, a simple aesthetic problem. A good skin-based angle of attack is also lacking because generalized vi- ligo is clearly epitomizing the view of skin diseases as simple targets of a systemic unknown dysregulation (diathesis), re? ecting the Hippocratic doctrine. This view has mostly restricted vitiligo to the manifestation of an auto-immune diathesis in the past 30 years. Thus, skin events, which are easily detected using skin biospies in most other situations, have not been precisely recorded, with the argument that a clinical diagnosis was suf? cient for the management (or most commonly absence of mana- ment) of the patient. This book is an international effort to summarize the information gathered about this disorder at the clinical, pathophysiological and therapeutic levels. Its primary aim is to bridge current knowledge at the clinical and investigative level, to point to the many unsolved issues, and to delineate future priorities for research.
Book Synopsis Autoimmunity in Vitiligo by : E. Helen Kemp
Download or read book Autoimmunity in Vitiligo written by E. Helen Kemp and published by . This book was released on 2011 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Autoimmune Diseases by : Noel R. Rose
Download or read book The Autoimmune Diseases written by Noel R. Rose and published by . This book was released on 1998 with total page 928 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Autoimmune Diseases comprehensively describes the clinical expressions of all known autoimmune diseases, as well as the experimental bases of autoimmunity and failure of tolerance. The scientific chapters include mechanisms of natural tolerance, the genetic basis of autoimmunity, the significance of apoptosis, the influence of cytokines, environmental influences, and experimental models. The clinical chapters cover autoimmune endocrine deficiencies, insulin-dependent diabetes, rheumatic disorders, neurological diseases, and diseases of the blood, skin, eye, kidney, and liver.
Book Synopsis Vitiligo Skin is Imprinted with Resident Memory CD8 T Cells Expressing CXCR3 by : Katia Boniface
Download or read book Vitiligo Skin is Imprinted with Resident Memory CD8 T Cells Expressing CXCR3 written by Katia Boniface and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Vitiligo is a chronic auto-immune depigmenting skin disorder that results from a loss of melanocytes. Multiple combinatorial factors have been involved in disease development, with a prominent role of the immune system, in particular T cells. After repigmentation, vitiligo frequently recurs in the same area, suggesting that vitiligo could involve the presence of resident memory T cells (TRM). Yet, the phenotype and contribution of effector memory T (TEM) cell subsets in the skin of vitiligo patients remain to date unclear and controversial due to the lack of extensive analyses in human skin. Therefore, we performed a thorough characterization of the phenotype and function of skin memory T cells in vitiligo. Stable and active vitiligo perilesional skin is enriched with a population of CD8 TRM expressing both CD69 and CD103 compared to psoriasis and control healthy skin. Expression of CXCR3 is observed on the majority of CD8 TRM in vitiligo and contained the population of melanocyte-specific CD8 T cells. These TRM cells displayed increased production of IFNg and TNFa with moderate cytotoxic activity. Our study highlights the presence of functional CD8 TRM in both stable and active vitiligo, reinforcing the concept of vitiligo as a skin memory disease. Remaining CD8 TRM in stable disease could play a role during disease flares, emphasizing the interest to target this cell subset in vitiligo.
Book Synopsis Skin Autoimmunity by : Ralf J. Ludwig
Download or read book Skin Autoimmunity written by Ralf J. Ludwig and published by Frontiers Media SA. This book was released on 2021-05-25 with total page 754 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Vitiligo written by James Nordlund and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph is a comprehensive expose of the disorder vitiligo. The book introduces the topic with a presentation about its cultural effects in the Middle East where vitiligo is exceptionally disabling to the affected person. Nehru as Prime Minister of India stated that vitiligo was a major impediment to the successful development of India. The book includes sections on the definition of vitiligo based on a consensus of world experts on vitiligo. There is a complete description of its clinical manifestations including the extracutaneous sites by world experts. Differentiation of vitiligo from other forms of depigmentation associated with malignancies is included with sufficient photographs to document differences. A section will present the physiological changes associated with depigmentation - a little known phenomena. The complete histology, differential diagnosis and animal models are major sections. The animal models are important in formulating theories about the causes of vitiligo. Most clinicians will find this section very informative. The book finishes with a thorough treatise on the principles of therapy.
