Immunology of HIV Infection

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Publisher : Springer Science & Business Media
ISBN 13 : 1489901914
Total Pages : 618 pages
Book Rating : 4.4/5 (899 download)

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Book Synopsis Immunology of HIV Infection by : Sudhir Gupta

Download or read book Immunology of HIV Infection written by Sudhir Gupta and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading experts provide the only comprehensive book examining all aspects of immune response and immune-based treatments for HIV infection. Contributions, divided into three sections, discuss basic mechanisms, immunopathogenesis of HIV infection, and immune-based therapies. Researchers thoroughly review vaccine-including prospects of T cell vaccine-and gene therapy for HIV infection. Additional topics include organization of HIV genes, the role of co-receptors in signaling of lymphocytes, and biological response modifiers. This reference is designed for basic and clinical researchers, internists, pediatricians, infectious disease specialists, neuropathologists, oncologists, and rheumatologists.

Immunology of HIV Infection

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Publisher : Springer
ISBN 13 : 9781489901927
Total Pages : 640 pages
Book Rating : 4.9/5 (19 download)

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Book Synopsis Immunology of HIV Infection by : Sudhir Gupta

Download or read book Immunology of HIV Infection written by Sudhir Gupta and published by Springer. This book was released on 2014-01-15 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading experts provide the only comprehensive book examining all aspects of immune response and immune-based treatments for HIV infection. Contributions, divided into three sections, discuss basic mechanisms, immunopathogenesis of HIV infection, and immune-based therapies. Researchers thoroughly review vaccine-including prospects of T cell vaccine-and gene therapy for HIV infection. Additional topics include organization of HIV genes, the role of co-receptors in signaling of lymphocytes, and biological response modifiers. This reference is designed for basic and clinical researchers, internists, pediatricians, infectious disease specialists, neuropathologists, oncologists, and rheumatologists.

Mathematical and Statistical Approaches to AIDS Epidemiology

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Publisher : Springer Science & Business Media
ISBN 13 : 3642934544
Total Pages : 416 pages
Book Rating : 4.6/5 (429 download)

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Book Synopsis Mathematical and Statistical Approaches to AIDS Epidemiology by : Carlos Castillo-Chavez

Download or read book Mathematical and Statistical Approaches to AIDS Epidemiology written by Carlos Castillo-Chavez and published by Springer Science & Business Media. This book was released on 2013-03-13 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 18 research articles of this volume discuss the major themes that have emerged from mathematical and statistical research in the epidemiology of HIV. The opening paper reviews important recent contributions. Five sections follow: Statistical Methodology and Forecasting, Infectivity and the HIV, Heterogeneity and HIV Transmission Dynamics, Social Dynamics and AIDS, and The Immune System and The HIV. In each, leading experts in AIDS epidemiology present the recent results. Some address the role of variable infectivity, heterogeneous mixing, and long periods of infectiousness in the dynamics of HIV; others concentrate on parameter estimation and short-term forecasting. The last section looks at the interaction between the HIV and the immune system.

Soluble Factors Mediating Innate Immune Responses to HIV Infection

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Publisher : Bentham Science Publishers
ISBN 13 : 1608050068
Total Pages : 168 pages
Book Rating : 4.6/5 (8 download)

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Book Synopsis Soluble Factors Mediating Innate Immune Responses to HIV Infection by : Massimo Alfano

Download or read book Soluble Factors Mediating Innate Immune Responses to HIV Infection written by Massimo Alfano and published by Bentham Science Publishers. This book was released on 2010 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Human Immunodeficiency Virus (HIV) infection represents one of the biggest challenges of current years. However, scientists and physicians still do not have an efficient therapy for preventing or eradicating the virus. The selection of drug-resistant stra"

Immunopathogenesis of HIV Infection

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Publisher : Springer Science & Business Media
ISBN 13 : 3642608671
Total Pages : 159 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Immunopathogenesis of HIV Infection by : Anthony S. Fauci

Download or read book Immunopathogenesis of HIV Infection written by Anthony S. Fauci and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last 5 years, major advances have been made in our understanding of the pathogenesis of human immunodeficiency virus (HIV) disease and in the development of new potent antiviral agents. With regard to HIV pathogenesis, several recent observations have not only changed our perspectives of HIV disease, but have been critical for the design of therapeutic strategies.

HIV and the Blood Supply

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Publisher : National Academies Press
ISBN 13 : 0309053293
Total Pages : 349 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis HIV and the Blood Supply by : Institute of Medicine

Download or read book HIV and the Blood Supply written by Institute of Medicine and published by National Academies Press. This book was released on 1995-10-05 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the early years of the AIDS epidemic, thousands of Americans became infected with HIV through the nation's blood supply. Because little reliable information existed at the time AIDS first began showing up in hemophiliacs and in others who had received transfusions, experts disagreed about whether blood and blood products could transmit the disease. During this period of great uncertainty, decision-making regarding the blood supply became increasingly difficult and fraught with risk. This volume provides a balanced inquiry into the blood safety controversy, which involves private sexual practices, personal tragedy for the victims of HIV/AIDS, and public confidence in America's blood services system. The book focuses on critical decisions as information about the danger to the blood supply emerged. The committee draws conclusions about what was doneâ€"and recommends what should be done to produce better outcomes in the face of future threats to blood safety. The committee frames its analysis around four critical area: Product treatmentâ€"Could effective methods for inactivating HIV in blood have been introduced sooner? Donor screening and referralâ€"including a review of screening to exlude high-risk individuals. Regulations and recall of contaminated bloodâ€"analyzing decisions by federal agencies and the private sector. Risk communicationâ€"examining whether infections could have been averted by better communication of the risks.

The Human Immunodeficiency Virus

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Publisher : Princeton University Press
ISBN 13 : 0691228833
Total Pages : 546 pages
Book Rating : 4.6/5 (912 download)

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Book Synopsis The Human Immunodeficiency Virus by : Emilio Emini

Download or read book The Human Immunodeficiency Virus written by Emilio Emini and published by Princeton University Press. This book was released on 2021-04-13 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt: The past few years have witnessed an explosive increase in our collective knowledge of the biology of the human immunodeficiency virus (HIV). Researchers have acquired new understanding of the virus's biochemistry, molecular biology, pathogenesis, genetics, and immunobiology. Resulting therapeutic advances have significantly prolonged the lives of thousands. Yet, the need to develop better therapies is ever more acute and--given the virus's continued spread through the human population--the need for an effective vaccine is urgent. These goals can be accomplished only through the experienced synthesis of information from the many disciplines participating in HIV research and through the insights of new investigators. This volume is designed to lower the barriers imposed on investigators by the sheer volume of available information--information that often can be found only in far-flung and specialized journals. It provides, in a single resource, an in-depth overview of the diverse areas that constitute HIV research. The result is a broad introduction for students and researchers new to the field as well as an integrated overview for researchers specialized in particular areas of HIV investigation. The volume will also benefit those seeking technical understanding of the virus's biology, including physicians treating HIV-infected patients. Each chapter is a comprehensive presentation of one area of current AIDS research--including work on the virus life cycle, epidemiology, genetics, protease and reverse transcriptase inhibitors, receptor and co-receptor interactions, therapeutic targets, clinical treatment, immunobiology, and vaccines--written by a leading researcher in that area. The contributors are Jon P. Anderson, Jan Balzarini, Elana Cherry, Thomas J. Coates, Chris Collins, Jon H. Condra, Mark B. Feinberg, Richard B. Gaynor, Matthias Götte, Daria J. Hazuda, Spyros Kalams, Nathaniel R. Landau, Gerald H. Learn, Norman L. Letvin, James I. Mullins, Willscott E. Naugler, David Nickle, Matthew Rain, Allen G. Rodrigo, Daniel Shriner, Shalom Spira, Mario Stevenson, Todd Summers, Catherine Ulich, Joseph P. Vacca, Mark A. Wainberg, Bruce D. Walker, and Yang Wang.

AIDS Pathogenesis

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Publisher : Springer Science & Business Media
ISBN 13 : 9401706859
Total Pages : 300 pages
Book Rating : 4.4/5 (17 download)

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Book Synopsis AIDS Pathogenesis by : H. Schuitemaker

Download or read book AIDS Pathogenesis written by H. Schuitemaker and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infection with the human immunodeficiency virus is characterized by the destruction of the host immune system as also reflected by a progressive loss of CD4-positive T-cells. This finally results in the host's incapacity to deal with opportunistic infections and the immune surveillance of tumors, a clinical status known as the Acquired Immunodeficiency Syndrome (AIDS). The book AIDS Pathogenesis provides the reader with a complete overview of the clinical course of HIV-1 infection. It describes the clinical aspects of primary infection, the different clinical outcomes of HIV-1 infection, and strategies for anti-viral treatment. In addition, more fundamental aspects of HIV-1 infection are reviewed. These include the biology of the virus and the novel insights in AIDS pathogenesis. Not only is the significance of an HIV-specific cellular and humoral immune response discussed, but also the possible incapacity of the adult human host to deal with T-cell destruction. Finally, the book discusses the currently used laboratory markers that allow for monitoring of the clinical course of infection.

The Biology of Dendritic Cells and HIV Infection

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Publisher : Springer Science & Business Media
ISBN 13 : 0387337857
Total Pages : 562 pages
Book Rating : 4.3/5 (873 download)

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Book Synopsis The Biology of Dendritic Cells and HIV Infection by : Sandra Gessani

Download or read book The Biology of Dendritic Cells and HIV Infection written by Sandra Gessani and published by Springer Science & Business Media. This book was released on 2007-03-09 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dendritic cells play the most vital part in inducing anti-viral immune responses in HIV and AIDS among many other viruses. Research on dendritic cells (DCs) is emerging as a fundamental aspect for the comprehension of the mechanisms underlying the pathogenesis of viral diseases. This volume focuses on the role of DCs in the pathogenesis and immunity of HIV-1 infection. It is the only comprehensive volume on pathogenesis and immunity of Dendritic Cells that also focuses on HIV.

HIV Interactions with Dendritic Cells

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Publisher : Springer Science & Business Media
ISBN 13 : 1461444322
Total Pages : 303 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis HIV Interactions with Dendritic Cells by : Li Wu

Download or read book HIV Interactions with Dendritic Cells written by Li Wu and published by Springer Science & Business Media. This book was released on 2012-09-11 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: Given rapid research progress and advance of the techniques in studying HIV interactions with host cells and factors, there is a critical need for a book on HIV interactions with DCs. The proposed book will aim for a broad readership to facilitate HIV/AIDS research and provide a practical tool for HIV researchers to continuously address novel questions. Specifically, the editors will summarize the literature in this field and provide critical analysis and future directions. International researchers will be invited as contributors of the book, highlighting authors who have contributed significantly to the field from different angles and aspects of virology, cell biology and immunology, etc.

Immunology and the Quest for an HIV Vaccine

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Publisher : Author House
ISBN 13 : 1468508296
Total Pages : 196 pages
Book Rating : 4.4/5 (685 download)

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Book Synopsis Immunology and the Quest for an HIV Vaccine by : Dr. Omar Bagasra, MD, PhD and Dr. Donald Gene Pace, PhD

Download or read book Immunology and the Quest for an HIV Vaccine written by Dr. Omar Bagasra, MD, PhD and Dr. Donald Gene Pace, PhD and published by Author House. This book was released on 2012-01-13 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: How many human immune systems are there? How old are they? Why is there no AIDS vaccine? Is a new approach needed? Why is public opinion growing skeptical of the scientific community after three decades of public awareness about HIV/AIDS? Consider answers to these puzzling questions. Learn from the decades of experience of two senior scholars: Dr. Omar Bagasra (an eminent molecular biologist, immunologist, and retrovirologist) and Dr. Donald Gene Pace (a highly published writer who examines public health policy). Explore intriguing new possibilities about human immunity, and the development of an effective AIDS vaccine. Read Immunology and the Quest for an HIV Vaccine. Benefit from an informed synthesis backed by a wealth of peer-reviewed scientific references. Review basic concepts of immunology, and stretch your perspective by contemplating this creative synthesis that provides a provocative treatise on the origin, evolution, and etiology of several forms of immune systems. Consider compelling ideas that will have an important bearing on HIV vaccine development. Enjoy this informative volume designed for anyone interested in the development of a safe AIDS vaccine, for anyone curious about present knowledge about human immunity, and for anyone yearning for a solution to the global pandemic that is AIDS.

HIV-Associated Immune Activation and Persistent Inflammation

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Publisher : Frontiers Media SA
ISBN 13 : 2889634388
Total Pages : 147 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis HIV-Associated Immune Activation and Persistent Inflammation by : Martin Hoenigl

Download or read book HIV-Associated Immune Activation and Persistent Inflammation written by Martin Hoenigl and published by Frontiers Media SA. This book was released on 2020-01-21 with total page 147 pages. Available in PDF, EPUB and Kindle. Book excerpt:

A Guide to AIDS

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Publisher : CRC Press
ISBN 13 : 1315317273
Total Pages : 168 pages
Book Rating : 4.3/5 (153 download)

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Book Synopsis A Guide to AIDS by : Omar Bagasra

Download or read book A Guide to AIDS written by Omar Bagasra and published by CRC Press. This book was released on 2017-03-31 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Guide to AIDS is succinct review of HIV/AIDS from a human-interest perspective. Chapters focus on some of the common patterns and prevention of HIV transmission and debunks misconceptions about HIV and AIDS. Brief descriptions the human immune system and epidemiology of HIV are included. The cultural component of disease, treatment and living with AIDS is central to much of this guide intended to synthesize, explain and de-mystify HIV and AIDS.

Cell Activation and Apoptosis in HIV Infection

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Publisher : Springer Science & Business Media
ISBN 13 : 1461519950
Total Pages : 246 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Cell Activation and Apoptosis in HIV Infection by : Jean-Marie Andrieu

Download or read book Cell Activation and Apoptosis in HIV Infection written by Jean-Marie Andrieu and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past decade, the global efforts in the control of HIV disease were basically concentrated on the search for anti-retroviral agents. So far, anti-HIV therapies have been shown to be disappointing because of rapid development of drug-resistant mutant variants. Despite this drawback in the therapeutic fight against HIV infection, antiviral research should be actively pursued. However, failure of antiviral therapy indicates that other avenues of research should be rapidly explored with the same energy. In this setting, striking advances have been recently made in the dissection and understanding of the viro-immunological processes governing the progressive destruction of lymphoid organs associated with AIDS develop ment, and HIV-induced activation and apoptosis have been identified as key phenomena of the immune system destruction. This book assembles the most recent advances on basic and clinical aspects ofT-cell activationiapoptosis in HIV infection and their implications for immunotherapy. These data were presented at an international symposium held on July 11-12, 1994, in Paris. The book is partitioned into 21 chapters covering four comprehensive fields: 1) T-celllmacrophage activation and HIV infection; 2) Apoptosis and viropathogenesis of HI V disease; 3) Apop tosis and immunopathogenesis ofHIV disease; 4) Mediators ofT-cell activationiapoptosis and therapeutic applications. We hope that this book will assist the readers in understanding recent advances in the viro-immunopathogenesis of HI V disease as well as the rationales for potential immune cell-targeted therapeutic interventions.

AIDS and Other Manifestations of HIV Infection

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Publisher : Elsevier
ISBN 13 : 008047196X
Total Pages : 1099 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis AIDS and Other Manifestations of HIV Infection by : Gary Wormser

Download or read book AIDS and Other Manifestations of HIV Infection written by Gary Wormser and published by Elsevier. This book was released on 2004-02-18 with total page 1099 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extensively revised and updated, the new edition of AIDS and Other Manifestations of HIV Infection is an essential reference resource providing a comprehensive overview of the biological properties of this etiologic viral agent, its clinicopathological manifestations, the epidemiology of its infection, and present and future therapeutic options. Expanded section on clinical manifestations includes new chapters on cardiovascular, renal and dermatologic manifestations of HIV infection Additional chapters on molecular diagnostic techniques, the role of host genetic variation in HIV infection and its manifestations, the discovery and development of new HIV medicines, analysis of HIV dynamics using mathematical models, toxicities of antiretroviral therapy, HIV drug susceptibility testing, practical therapeutics and the global impact of HIV and AIDS

HIV-Induced Damage of B Cells and Production of HIV Neutralizing Antibodies

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Publisher : Frontiers Media SA
ISBN 13 : 2889454614
Total Pages : 171 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis HIV-Induced Damage of B Cells and Production of HIV Neutralizing Antibodies by : Francesca Chiodi

Download or read book HIV-Induced Damage of B Cells and Production of HIV Neutralizing Antibodies written by Francesca Chiodi and published by Frontiers Media SA. This book was released on 2018-03-27 with total page 171 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multiple dysfunctions take place in the B cell compartment during HIV-1 infection, comprising depletion of resting memory B cells carrying serological memory to vaccines and previously met pathogens. In addition, population of B cells characterized by the expression of exhaustion markers are enlarged during HIV-1 infection. Antibodies with the capacity to neutralize a broad range of HIV-1 isolates can be detected only in a minority of infected patients, after a year or more from acute infection. An open question is whether the inability of producing neutralizing HIV-1 antibodies is somehow linked to the B cell immunopathology observed in patients. In this research topic we invited scientists to summarize the current state of knowledge on regulation and development of B cells and antibody responses during HIV-1 infection; fifteen contributions were received comprising both reviews and original articles. The articles are related to B cell dysfunctions identified in HIV-1 infected individuals, production of different types of antibodies (neutralizing versus non neutralizing, and of different isotypes) in vivo during HIV-1 infection and the biological factors which may impact on this process, clinical potential and applications of anti-HIV antibodies and how to achieve neutralizing antibody responses to HIV-1 epitopes upon vaccination. The topic has gathered articles on front-line research undertaken in the field of B cells and antibodies in HIV-1 infection. It is our hope that the collection of articles presented in this book may be useful for new and experienced scholars in the field and add a piece to the complex puzzle of knowledge needed for the development of an HIV-1 vaccine.

The Emergence of AIDS

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Publisher :
ISBN 13 :
Total Pages : 292 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis The Emergence of AIDS by : Kenneth H. Mayer

Download or read book The Emergence of AIDS written by Kenneth H. Mayer and published by . This book was released on 2000 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: The contributors of this volume explore the history of HIV and its enormous impact on today's understanding of how viruses undergo their processes on the nonhuman and human. It explains how the HIV research has taught us about the human immune system and possibilities for new therapies for handling viruses. This book highlights the lessons learned over the past 20 years about AIDS and the lessons learned from AIDS, and highlights the knowledge that may advance worthwhile strategies for combating HIV and AIDS in the future. The 11 chapters include: The Virus Versus the Immune System, How Infectious is Infectious, The Race Against Time: The Challenge for Clinical Trials, Sex and Drugs and the Virus, and more.