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Author : G. P. Talwar
Publisher :
ISBN 13 : 9781461319047
Total Pages : 284 pages
Book Rating : 4.3/5 (19 download)
Download or read book Immunological Approaches to the Diagnosis and Therapy of Breast Cancer written by G. P. Talwar and published by . This book was released on 1987-08-01 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Roberto L. Ceriani
Publisher : Springer
ISBN 13 :
Total Pages : 296 pages
Book Rating : 4.3/5 (91 download)
Download or read book Immunological Approaches to the Diagnosis and Therapy of Breast Cancer written by Roberto L. Ceriani and published by Springer. This book was released on 1987-08-31 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Once again we have gathered to discover and evaluate advances made in our ability to understand. diagnose and possibly treat breast cancer with the new reagents provided by monoclonal antibody techniques. In the last two years since our first International Workshop on Monoclonal Antibodies and Breast Cancer there has been an enormous surge in the number and quality of applications for these new reagents. Solid achievements have been made in identification and quantitation of estrogen and progesterone receptors. in histopathological diagnostic procedures. in serum diagnosis. and we are witnessing now the first attempts to treat breast cancer with immunoconjugates. Cytosolic estrogen receptors can now be quantitated with monoclonal antibodies. and also their cellular distribution can be directly assessed histologically. In addition. monoclonal antibodies to progesterone receptors have been generated that show promise in having similar uses as those to the estrogen receptor. In the field of diagnosis. the use of monoclonal antibodies has permitted the development of serological approaches for early diagnosis by identifying and measuring breast epithelial antigens in serum. and of histological approaches for establishing criteria for breast cancer dissemination and prognosis. With great expectations we are all following developments in the area of breast cancer treatment using conjugates of anti-breast epithelial monoclonal antibodies which are now confirming earlier reports in affecting breast tumor control. The recent creation of newer monoclonal antibodies and conjugates await experimentation and clinical trials to determine their value.
Author : G.P. Talwar
Publisher : Springer Science & Business Media
ISBN 13 : 146131903X
Total Pages : 269 pages
Book Rating : 4.4/5 (613 download)
Download or read book Immunological Approaches to the Diagnosis and Therapy of Breast Cancer written by G.P. Talwar and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: Once again we have gathered to discover and evaluate advances made in our ability to understand. diagnose and possibly treat breast cancer with the new reagents provided by monoclonal antibody techniques. In the last two years since our first International Workshop on Monoclonal Antibodies and Breast Cancer there has been an enormous surge in the number and quality of applications for these new reagents. Solid achievements have been made in identification and quantitation of estrogen and progesterone receptors. in histopathological diagnostic procedures. in serum diagnosis. and we are witnessing now the first attempts to treat breast cancer with immunoconjugates. Cytosolic estrogen receptors can now be quantitated with monoclonal antibodies. and also their cellular distribution can be directly assessed histologically. In addition. monoclonal antibodies to progesterone receptors have been generated that show promise in having similar uses as those to the estrogen receptor. In the field of diagnosis. the use of monoclonal antibodies has permitted the development of serological approaches for early diagnosis by identifying and measuring breast epithelial antigens in serum. and of histological approaches for establishing criteria for breast cancer dissemination and prognosis. With great expectations we are all following developments in the area of breast cancer treatment using conjugates of anti-breast epithelial monoclonal antibodies which are now confirming earlier reports in affecting breast tumor control. The recent creation of newer monoclonal antibodies and conjugates await experimentation and clinical trials to determine their value.
Author : Nima Rezaei
Publisher : Springer Nature
ISBN 13 : 3031658086
Total Pages : 436 pages
Book Rating : 4.0/5 (316 download)
Download or read book Breast Cancer Genetics, Immunology, and Immunotherapy: An Interdisciplinary Approach written by Nima Rezaei and published by Springer Nature. This book was released on with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Mai F. Tolba
Publisher : Frontiers Media SA
ISBN 13 : 2889740536
Total Pages : 172 pages
Book Rating : 4.8/5 (897 download)
Download or read book Immunotherapy as an Evolving Approach for the Treatment of Breast Cancer written by Mai F. Tolba and published by Frontiers Media SA. This book was released on 2022-01-13 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : D. Drahovsky
Publisher : Springer Science & Business Media
ISBN 13 : 3642736424
Total Pages : 191 pages
Book Rating : 4.6/5 (427 download)
Download or read book Human Malignancies written by D. Drahovsky and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: To scientists, oncology means research on the disease of cancer. The connection between basic research and clinical oncology, however, is not always very clear. Basic research sometimes appears to be an art that is practiced for its own sake and admired for its perfection. The clinician wishes to interpret the issues addressed by basic research, as he is eager to obtain answers to the questions that clinical oncology leaves open. These are, among others, questions as to the etiology and pathogenesis of neoplasma in human beings. In spite of all the technological advances during the past 10 years, the guidelines for new treatments of human leukemias and tumors are still unsatisfactory. The dialogue between researchers and clinicians must never cease, so that these questions can be formulated in such a way that science may be able to answer them. Both parties should cooperate whenever this is useful and possible. Prospectively planned clinical trials on the diagnosis and therapy of neoplasias offer a good opportunity for research involving patients. Tumor and/or blood tests run by reference laboratories on a great number of patients with the same diagnosis can lead to clinically relevant basic research. Using clinical studies in basic research programs permits us to trace missing pieces in the puzzle of cancer and put them into place.
Author : R. Ceriani
Publisher : Springer Science & Business Media
ISBN 13 : 1461326176
Total Pages : 327 pages
Book Rating : 4.4/5 (613 download)
Download or read book Monoclonal Antibodies and Breast Cancer written by R. Ceriani and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: Breast cancer, being a disease with very high prevalence in the female population, has permanently attracted the attention of biologists, biochemists, pathologists, surgeons, and oncologists. In the U.S. alone approximately 120,000 new cases are diagnosed and 37,000 deaths a year are recorded as an outcome. Early diagnosis, clear cut prognosis and the hope of new therapeutic approaches has spurred the enthusiasm of researchers, who with the advent of newer methodologies, tried to employ it in different approaches to the breast cancer patient. In spite of the efforts devoted towards the creation of new approaches, reagents and procedures taking advantage of special characteristics of the breast tissue were slow to come. In general, most diagnostic and prognostic techniques were those shared and applied to other carcinomas. In the early seventies we discovered the first sets of antigens associated with breast epithelial tissue both in the mouse and the human. The recognition of such group of molecules, present in the milk fat globule membrane, gave impetus to several studies in these areas. These mammary cell surface antigens proved useful in several diagnostic approaches such as radioimaging, histochemical and serum assay procedures. However, the apparently inherent limitations of polyclonal antibodies reduced the impact of these novel approaches.
Author : R.L. Ceriani
Publisher : Springer Science & Business Media
ISBN 13 : 1461537401
Total Pages : 369 pages
Book Rating : 4.4/5 (615 download)
Download or read book Breast Epithelial Antigens written by R.L. Ceriani and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: The wealth of research results in the area of breast cancer diagnosis and therapy with monoclonal antibodies presented in previous workshops is now complemented with a new rendition of the proceedings of the 4th Workshop on Monoclonal Antibodies and Breast Cancer. held in San Francisco on November 5-6. 1990. Basic science findings reported in previous workshops have now percolated to the clinical level and have become immunoassays and imaging and therapy reagents. as the program shows us. Thus. the latest discoveries in immunology. biochemistry and molecular biology of breast epithelial antigens and their corresponding antibodies have produced newer diagnostic tests and therapeutic approaches that are altering and improving the way we attack breast cancer. The recent spectacular and rapid advancements in the molecular biology of several of the breast epithelial antigens are presented in this volume. The way in which the final assembly of different components of the breast antigens is achieved and their functions are now within our grasp as a result of new understanding of molecular structure of these breast antigens. In addition. newer immunoassays aiming at the earliest detection of the disease are also described that integrate with promising attempts at imaging and radioimmunotherapy to set the stage for new oncological possibilities in breast cancer treatment. All these areas of intense involvement of scientists with diverse specialties are presented in this volume. which proves the need for multidisciplinary approaches to increase our chances for success in this field of medical research.
Author : Roberto L. Ceriani
Publisher : Springer Science & Business Media
ISBN 13 : 1461524431
Total Pages : 227 pages
Book Rating : 4.4/5 (615 download)
Download or read book Antigen and Antibody Molecular Engineering in Breast Cancer Diagnosis and Treatment written by Roberto L. Ceriani and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: Today, advances in the area of immunology and breast cancer are made at an increasing rate, yielding an amount of information that can become unwieldy. The opportunity for scientists in this area of research to gather together to exchange results and working hypotheses represents, in my belief, a very attractive proposition. With this in mind, these workshops have been convened with two year intervals for the last ten years. In each of them, selected topics have been highlighted. The present workshop underscores the large advancements made in the molecular biology of both breast cancer associated antigens and their corresponding antibodies. Understanding the genetic information for the expression of these antigens has been recently advanced leading to preparation of molecularly engineered reagents for use in vaccination, serum assays, and immunizations for novel antibody production. In the anti-breast cancer antibody field the availability of molecular engineering approaches to humanize murine antibodies has induced intense interest in the creation of less immunogenic antibody forms that are now available for clinical testing. Clinical studies using anti-breast murine antibody continue to be carried out and are presented at this meeting establishing a base line for safety and efficaciousness in imaging and immunotherapy that it is hoped will be superseded by the humanized forms. Basic immunology and immunochemistry studies in breast cancer are also included in this workshop that demonstrate the fast pace at which this research is advancing in many laboratories worldwide.
Author : Azadeh Shahidian
Publisher : Academic Press
ISBN 13 : 0128178108
Total Pages : 276 pages
Book Rating : 4.1/5 (281 download)
Download or read book Bio-Engineering Approaches to Cancer Diagnosis and Treatment written by Azadeh Shahidian and published by Academic Press. This book was released on 2020-05-14 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioengineering Approaches to Cancer Diagnosis and Treatment is written for an audience of senior undergraduate students and graduate students in mechanical, electrical and biomedical engineering fields and other professionals in medicine. It is ideally structured for teaching and for those who are working in cancer bioengineering or interdisciplinary projects. The book's authors bring a unique perspective from their expertise in immunology, nanobiomaterials and heat transfer. Topical coverage includes an introduction to the fundamentals of bioengineering and engineering approaches for cancer diagnosis, cancer treatment via case studies, and sections on imaging, immunotherapy, cell therapy, drug delivery, ultrasound and microfluidics in cancer treatment. Provides fully supported case studies relating to cancer diagnosis and therapy Pairs the basic fundamentals of engineering and biomedical engineering and applies them to the diagnosis of cancer
Author : Lisa Katherine Gilliam
Publisher :
ISBN 13 :
Total Pages : 426 pages
Book Rating : 4.:/5 (47 download)
Download or read book Immune-based Approaches to Breast Cancer Susceptibility and Treatment written by Lisa Katherine Gilliam and published by . This book was released on 1998 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Enrico Mihich
Publisher : John Wiley & Sons
ISBN 13 :
Total Pages : 608 pages
Book Rating : 4.3/5 (91 download)
Download or read book Immunological Approaches to Cancer Therapeutics written by Enrico Mihich and published by John Wiley & Sons. This book was released on 1982 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Ronald B Herberman
Publisher :
ISBN 13 : 9781461326304
Total Pages : 244 pages
Book Rating : 4.3/5 (263 download)
Download or read book Cancer Immunology written by Ronald B Herberman and published by . This book was released on 1986-02-01 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Nima Rezaei
Publisher : Springer
ISBN 13 : 9783031658075
Total Pages : 0 pages
Book Rating : 4.6/5 (58 download)
Download or read book Breast Cancer Genetics, Immunology, and Immunotherapy: An Interdisciplinary Approach written by Nima Rezaei and published by Springer. This book was released on 2024-07-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetics have a role in the presence of breast cancer, while the potential role of the immune system leads to consideration of immunotherapy in the treatment of the disease, particularly in metastatic triple-negative breast cancer. The sixth volume of the “Interdisciplinary Cancer Research” series, entitled “Breast Cancer Genetics, Immunology, and Immunotherapy: An Interdisciplinary Approach” publishes comprehensive volumes on immune and genetic mechanisms of breast cancer diagnosis and prognosis. The role of molecular genetics, interleukins, chemokine receptor, and tumor-infiltrated lymphocytes-TILS in breast cancer are explained. Targeting myeloid determinants, SiRNA loaded in drug delivery nanosystems, nucleic acid and drug dual agent nanoplatforms, and oncolytic virotherapy are also discussed in the treatment of breast cancer, particularly in multidrug resistant and metastatic breast cancer. This interdisciplinary series is of special value to researchers working on immunology, genetics, and practitioners working on oncology. This is the main concept of Cancer Immunology Project (CIP), which is a part of Universal Scientific Education and Research Network (USERN). This interdisciplinary book will be of special value to researchers, oncologists, geneticists, and immunologists who wish to extend their knowledge on breast cancer.
Author : Ronald B. Herberman
Publisher : Springer
ISBN 13 : 9781461296430
Total Pages : 230 pages
Book Rating : 4.2/5 (964 download)
Download or read book Cancer Immunology: Innovative Approaches to Therapy written by Ronald B. Herberman and published by Springer. This book was released on 2012-01-04 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is the second in the 'Cancer Treatment and Research' series focussing on basic and clinical tumor immunology. It has a rather different focus or emphasis from that of the first volume, published two years ago. That work (Basic and Clinical Tumor Immunology, R.B. Herberman, ed., Martinus Nijhoff Publishers, 1983) devoted considerable attention to up dated summaries in various areas of classical tumor immunology: specific antitumor immunity, the immunologic competence of cancer patietns, char acterization of human tumor-associated antigens, the ability to propagate specifically immune T cells in culture in the presence of interleukin 2, and the use of such cells for adoptive immunotherapy of established tumors. of evidence concerning the immune However, it also reviewed the status surveillance hypothesis and pointed out the need to consider non-T cell mediated mechanisms of host resistance. In particular, one chapter sum marized information on the role of macrophages in host resistance against tumors. The present volume continues to emphasize one of the major themes of the first volume, innovative approaches to the therapy of cancer. It involves contributions from leading investigators on several primary types of therapeutic interventions related to monoclonal antibodies, the col laboration of monoclonal antibodies with macro phages to mediate antibody dependent cellular cytotoxicity, lymphokines, tumor vaccines, and natural killer cells. It also has an up-to-date summary of the immunologic aspects of the exciting and promising work being performed on human T cell leukemia virus in the laboratory of Dr. Robert Gallo.
Author : Antoinette R. Tan
Publisher : Springer
ISBN 13 : 3319699806
Total Pages : 187 pages
Book Rating : 4.3/5 (196 download)
Download or read book Triple-Negative Breast Cancer written by Antoinette R. Tan and published by Springer. This book was released on 2018-01-11 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: This guide provides practical information that will assist clinicians involved in the diagnosis, assessment, treatment, and follow-up care of patients with triple-negative breast cancer. After opening chapters on the pathologic evaluation, clinical presentation, genetics, and imaging features, the full range of current treatment approaches is thoroughly reviewed from a multidisciplinary perspective. Readers will find up-to-date information and guidance on surgical management, radiation therapy, tailored adjuvant therapy, neoadjuvant treatment, systemic treatment for metastatic disease, molecular profiling, and targeted therapy. The coverage is completed by discussion of special issues in young women with triple-negative breast cancer and individualization of the management approach in older patients affected with the disease. All healthcare professionals who care for patients with triple-negative breast cancer will find the book to be an invaluable source of expert advice on the issues faced in real-world practice.
Author : Roberto Ceriani
Publisher : Springer
ISBN 13 : 1475712960
Total Pages : 249 pages
Book Rating : 4.4/5 (757 download)
Download or read book Breast Cancer Immunodiagnosis and Immunotherapy written by Roberto Ceriani and published by Springer. This book was released on 2013-04-17 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: The convening of the 3rd International Workshop on Monoclonal Antibodies and Breast Cancer had the character of a self-search exercise. After almost a decade of research in the basic and applied aspects of the use of serological means to diagnose and possibly treat breast cancer several milestones have been reached. Among them a clear understanding of immunopathological use and limitations of monoclonal antibodies against breast epithelium, the complete development and clinical use of immunoassays for circulating breast epithelial antigens, the striking advances in the diagnostic use of monoclonal antibodies to estrogen and progesterone receptor proteins and the first communications on proposed immunotherapeutic use of different conjugates of anti-breast antibodies. New areas of investigation have developed in our field, some which are reaching a full blossom while others are still facing obstacles and at times a re-definition of their goals and objectives. These meetings have acted in a way as a clearing house and have permitted their attendees to derive predictions that have helped shape future research and fine-tune objectives. But above all, the re-evaluation of past research at these Workshops and the renewed excitement brought to them by new information has helped generate a momentum and enthusiasm that assures for the future large scientific gains.
