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Author : Felix Haurowitz
Publisher :
ISBN 13 : 9780470360750
Total Pages : 322 pages
Book Rating : 4.3/5 (67 download)
Download or read book Immunochemistry and the Biosynthesis of Antibodies written by Felix Haurowitz and published by . This book was released on 1968 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antikörper / Biochemie.
Author : R. Nezlin
Publisher : Springer Science & Business Media
ISBN 13 : 1468417916
Total Pages : 395 pages
Book Rating : 4.4/5 (684 download)
Download or read book Biochemistry of Antibodies written by R. Nezlin and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: When the history of immunology in the twentieth century is written, the decade of the 1960's will, in all probability, stand out as the period of greatest advance in the development of molecular immunology. It is appropriate and useful, therefore, that a schol arly and integrated presentation of this progress should be made available in English. The translation of Dr. Nezlin's "Biochem istry of Antibodies" from Russian admirably fulfills this need in the form of a scientific monograph directed to medical and biolog ical scientists. The appearance of this monograph also serves to emphasize the conceptual unification of diverse immunological phenomena which has emerged from progress in molecular immunology. This unity is a consequence of the key role played by the antibody mol ecule (either in solution or cell-bound) in every biological process properly described as immunological. Indeed, immunology as an independent natural science can be described as the study of the structure, interactions, and biosynthes is of the antibody molecule.
Author : R. S. Nezlin
Publisher : Springer
ISBN 13 :
Total Pages : 392 pages
Book Rating : 4.3/5 (91 download)
Download or read book Structure and Biosynthesis of Antibodies written by R. S. Nezlin and published by Springer. This book was released on 1977-04 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Miroslav Ferencik
Publisher : Springer Science & Business Media
ISBN 13 : 9401115524
Total Pages : 529 pages
Book Rating : 4.4/5 (11 download)
Download or read book Handbook of Immunochemistry written by Miroslav Ferencik and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book appeared in two previous Slovak editions for university students in Czechoslovakia. This edition presents a completely new version updated according to recent advances not only in immunochemistry and essential immunology but also in molecular biology, biochemistry and molecular genetics. The scope of the book is considerable since the goal was to cover the field of immunochemistry from the widest point of view including both the topic and methods of contemporary immunochemistry. Each chapter provides basic information on a specific subtopic, clearly and understandab ly, and presents principles of individual immunochemical methods. I am confident that the book will fill the gap between the books on essential immunology and highly specialised books on individual areas of immunoche mistry (e. g. on antibodies, antigens, numerous immunochemical techniques, etc. ). It may also prove useful for beginning investigators from different biological and medical fields as it supplies basic information needed for solving their scientific problems by immunochemical approaches. I do hope that readers will find the text stimulatory and pleasury to read. I wish to thank all colleagues and friends for supplying their own results, suggestions and for their encouraging comments. My thanks go also to the editors and publishers for their valuable contribution to the preparation of the book. 1 Introduction The term immunochemistry was coined by the Swedish chemist ARRHENIUS who used it for the first time in his lectures in 1907.
Author : Curtis A. Williams
Publisher : Academic Press
ISBN 13 : 1483220605
Total Pages : 586 pages
Book Rating : 4.4/5 (832 download)
Download or read book Antigen-Antibody Reactions In Vivo written by Curtis A. Williams and published by Academic Press. This book was released on 2014-05-10 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods in Immunology and Immunochemistry, Volume V: Antigen-Antibody Reactions In Vivo deals primarily with immune phenomena in tissues or in cell preparations. This book covers a variety of topics, including anaphylaxis, tolerance, immune suppression with chemical agents, radiation effects, antibody synthesis in vitro, immunological methods, and applied electron microscopy. Organized into 10 chapters, this volume begins with an overview of systemic anaphylaxis investigations in other more resistant species. This text then presents the analysis of mechanisms involved in the pathogenesis of the Arthus phenomenon, which shed light on the understanding of other lesions of hypersensitivity. Other chapters consider the effects of antigen–antibody interaction on connective tissue. This book discusses as well the degree and duration of acquired tolerance. The final chapter deals with the application of electron microscopy in the elucidation of the mechanisms of immune reactions. This book is a valuable resource for immunologists, students, and research workers.
Author : Sir Frank Macfarlane Burnet
Publisher :
ISBN 13 :
Total Pages : 162 pages
Book Rating : 4.E/5 ( download)
Download or read book The Production of Antibodies written by Sir Frank Macfarlane Burnet and published by . This book was released on 1949 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : L. E. Glynn
Publisher :
ISBN 13 :
Total Pages : 164 pages
Book Rating : 4.4/5 (91 download)
Download or read book Antibody Production written by L. E. Glynn and published by . This book was released on 1981 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical guide to the production of antibodies. Describes the biosynthesis of antibody molecules by B lymphocytes and their progeny, the use of genetic markers in the elucidation of mechanisms of antibody synthesis, and of the generation of antibody diversity. Also deals with anomalies in antibody production which result in immunoglobulinopathies, involving qualitative or quantitative abnormalities, or both, in the immunoglobulins.
Author : Kenneth Murphy
Publisher : Garland Science
ISBN 13 : 9780815344575
Total Pages : pages
Book Rating : 4.3/5 (445 download)
Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Author : M. Zouhair Atassi
Publisher : Springer Science & Business Media
ISBN 13 : 1461341906
Total Pages : 495 pages
Book Rating : 4.4/5 (613 download)
Download or read book Immunochemistry of Proteins written by M. Zouhair Atassi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: The structural features responsible for the immunogenicity of certain parts of native protein molecules have been of interest to immunochemists and protein chemists for over three decades. Following the early work of Land steiner in 1942, which showed that peptide fragments from silk fibroin exhibited an inhibitory activity toward the reaction of the protein with its antibodies, fragments from many other protein systems have been isolated and studied. However, no concerted effort was (or could be) devoted to the elucidation of the complete antigenic structure of a protein. In order for these endeavors to be successful and meaningful, knowledge of both the amino acid sequence and the detailed three-dimensional structure of the protein is necessary. Such information was not available for a protein until early in the 1960s. This and the fact that protein chemistry was not in fact sufficiently developed early in the 1960s to enable the successful completion of the entire antigenic structure of a protein were major contributing factors for the slow progress in this field. Determination of the antigenic structures of proteins therefore posed a chemical challenge of enormous proportions. For these reasons, many investigators diverted their attention to study of the immunochemistry of homo- or mixed amino acid polymers in the hope that the information derived from these systems might prove useful in the understanding of the immunochemistry of proteins.
Author : John E. Butler
Publisher : CRC Press
ISBN 13 : 9780849353949
Total Pages : 334 pages
Book Rating : 4.3/5 (539 download)
Download or read book Immunochemistry of Solid-Phase Immunoassay written by John E. Butler and published by CRC Press. This book was released on 1991-07-23 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunochemistry of Solid-Phase Immunoassay fills a niché in the field of immunoassay and immunology. Although solid-phase immunoassay constitutes a major technology in biology and medicine, there is no comprehensive source devoted to the immunochemical principles involved. As a result, this book will benefit students, technicians, and researchers who use this technology, as well as immunodiagnostic and biotech companies who develop the technology. The book is not a methods manual; instead, it incorporates the concepts, data, and opinions of more than 25 investigators working in this field. Topics discussed include: the chemistry of solid-phases, the behavior or antibodies and antigens on solid phases, membrane solid-phases, reaction kinetics, antigen quantitation, enzyme systems, photophysics, immunochemical considerations in data analyses, multianalyte assays and occupancy concepts, antibody quantitation, streptavidin, a review of data analysis software, and solid-phase peptide immunoassay.
Author : F. Inman
Publisher : Springer Science & Business Media
ISBN 13 : 1475713436
Total Pages : 196 pages
Book Rating : 4.4/5 (757 download)
Download or read book Contemporary Topics in Immunochemistry written by F. Inman and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1897, Ehrlich suggested that natural preformed receptors from the surface of cells provided immunity to various chemical substances. Many years later, in 1940, Pauling proffered the concept that antibodies comprised a single poly peptide chain and that each end of the protein could form an antigen-binding site. Burnet tried to explain the diversity of antibody specificity by hypothesizing that it was cell-derived. These hypotheses probably have led to as much or more experimentation and discussion than any other of the many conjectures set forth to explain immunity on a molecular and cellular basis. Extensive investigations, initially stimulated by these propositions, proved Pauling's notion incorrect. In its demise, however, the multichain structure of the immunoglobulins was realized. In retrospect it be comes obvious that Ehrlich's idea, though not correct, was borne of amazing logic and cognition. Expansion of Burnet's theory seems to be occurring presently; much excitement is engendered by the finding of cell-bound immunoglobulin receptors. Ouring the preceding dozen years, immunochemists have accumulated enormous quantities of data. Though there is so much yet to be done, as a result of this research one may now discuss antigen-binding sites in relation to the protein's primary structure. There is even considerable understanding of the cellular assembly of some immunoglobulins. Entire books can be written about the chemistry of antigens and of complement.
Author : Eugene D. Day
Publisher :
ISBN 13 :
Total Pages : 730 pages
Book Rating : 4.:/5 (44 download)
Download or read book Advanced Immunochemistry written by Eugene D. Day and published by . This book was released on 1990-03-19 with total page 730 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive treatment of immunochemistry theory offers the kind of information essential to furthering the biotechnological development of advances in molecular and cellular immunology. More than just a review of the principles, the Second Edition of Advanced Immunochemistry presents a full exposition of modern immunochemical theory and knowledge. Incorporating the major developments in immunochemistry over the past two decades, this exciting text presents the latest information on the progress in such areas as: immunoglobulin structures; applications of molecular genetics to the understanding of immunoglobulin genes and supergene families; molecular and cellular bases of antibody diversity; antibody binding to specific epitopes of antigen molecules; and idiotypy. This Second Edition will serve as a comprehensive reference to the structure and function of immunoglobulins and as a basis for understanding the complexities of immune responses.
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309173051
Total Pages : 74 pages
Book Rating : 4.3/5 (91 download)
Download or read book Monoclonal Antibody Production written by National Research Council and published by National Academies Press. This book was released on 1999-05-06 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt: The American Anti-Vivisection Society (AAVS) petitioned the National Institutes of Health (NIH) on April 23, 1997, to prohibit the use of animals in the production of mAb. On September 18, 1997, NIH declined to prohibit the use of mice in mAb production, stating that "the ascites method of mAb production is scientifically appropriate for some research projects and cannot be replaced." On March 26, 1998, AAVS submitted a second petition, stating that "NIH failed to provide valid scientific reasons for not supporting a proposed ban." The office of the NIH director asked the National Research Council to conduct a study of methods of producing mAb. In response to that request, the Research Council appointed the Committee on Methods of Producing Monoclonal Antibodies, to act on behalf of the Institute for Laboratory Animal Research of the Commission on Life Sciences, to conduct the study. The 11 expert members of the committee had extensive experience in biomedical research, laboratory animal medicine, animal welfare, pain research, and patient advocacy (Appendix B). The committee was asked to determine whether there was a scientific necessity for the mouse ascites method; if so, whether the method caused pain or distress; and, if so, what could be done to minimize the pain or distress. The committee was also asked to comment on available in vitro methods; to suggest what acceptable scientific rationale, if any, there was for using the mouse ascites method; and to identify regulatory requirements for the continued use of the mouse ascites method. The committee held an open data-gathering meeting during which its members summarized data bearing on those questions. A 1-day workshop (Appendix A) was attended by 34 participants, 14 of whom made formal presentations. A second meeting was held to finalize the report. The present report was written on the basis of information in the literature and information presented at the meeting and the workshop.
Author : Elvin Abraham Kabat
Publisher :
ISBN 13 :
Total Pages : 576 pages
Book Rating : 4.3/5 (91 download)
Download or read book Structural Concepts in Immunology and Immunochemistry written by Elvin Abraham Kabat and published by . This book was released on 1976 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : M.W. Steward
Publisher : Springer Science & Business Media
ISBN 13 : 9400955723
Total Pages : 97 pages
Book Rating : 4.4/5 (9 download)
Download or read book Antibodies: Their structure and function written by M.W. Steward and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 97 pages. Available in PDF, EPUB and Kindle. Book excerpt: The student of biological science in his final years as an undergraduate and his first years as a graduate is expected to gain some familiarity with current research at the frontiers of his discipline. New research work is published in a perplexing diversity of publications and is inevitably con cerned with the minutiae of the subject. The sheer number of research journals and papers also causes confusion and difficulties of assimilation. Review articles usually presuppose a background knowledge of the field and are inevitably rather restricted in scope. There is thus a need for short but authoritative introductions to those areas of modern biological research which are either not dealt with in standard introductory textbooks or are not dealt with in sufficient detail to enable the student to go on from them to read scholarly reviews with profit. This series of books is designed to satisfy this need. The authors have been asked to produce a brief outline of their subject assuming that their readers will have read and remembered much of a standard introductory textbook of biology. This outline then sets out to provide by building on this basis, the conceptual framework within which modern research work is progressing and aims to give the reader an indication of the problems, both conceptual and practical, which must be overcome if progress is to be maintained.
Author : O. J. Plescia
Publisher : Springer Science & Business Media
ISBN 13 : 3642876684
Total Pages : 686 pages
Book Rating : 4.6/5 (428 download)
Download or read book Nucleic Acids in Immunology written by O. J. Plescia and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 686 pages. Available in PDF, EPUB and Kindle. Book excerpt: Two fields have played a leading role in biomedical research in recent years, the biochemistry of nucleic acids and immunology. Yet, with the exception of those aspects which have been concerned with antibody synthesis as an example of protein synthesis, there was until recently a lack of direct association between the two fields. Until quite recently the antigenicity of nucleic acids was still in doubt and indeed represented a controversial subject. Also, the exact role of the various nucleic acids in various stages of antibody synthesis was uncertain. These skepticisms and uncertainties disappeared rapidly in the last few years. New experi mental approaches brought the realization that nucleic acids, under appropriate conditions, are indeed immunogenic, and that the resulting antibodies can furnish new tools for the exploration of the mplecular structure of the all-important family of nucleic acid molecules. ' At the same time, the recognition of the antigenicity of nucleic acids brought a new level of understanding to certain auto-immune diseases and pro vided new material for the exploration of the role of a carrier in immune responses. Side by side with this development was the almost explosive development of new experimental approaches and new ideas pertaining to the problem of antibody formation. Nucleic acids in their various forms were recognized as playing an expected major role in the activation of antibody-forming cells. Perhaps less to be expected was the role they can playas non-specific stimulators of antibody formation.
Author : R. Nezlin
Publisher :
ISBN 13 : 9781468417920
Total Pages : 404 pages
Book Rating : 4.4/5 (179 download)
Download or read book Biochemistry of Antibodies written by R. Nezlin and published by . This book was released on 1970-04-01 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt:
