Immunobiology and Prophylaxis of Human Herpesvirus Infections

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Publisher : Springer Science & Business Media
ISBN 13 : 1468458531
Total Pages : 289 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Immunobiology and Prophylaxis of Human Herpesvirus Infections by : Carlos Lopez

Download or read book Immunobiology and Prophylaxis of Human Herpesvirus Infections written by Carlos Lopez and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: No one whose opinion deserves a moment's consideration can doubt that most of the great positive evils of the world are in themselves removable, and will, if human affairs continue to improve, be in the end reduced to narrow limits. J. S. Mill, Utilitarianism, II, 1863 Mill was not writing about herpesviruses, but had he known them as we do, he would have included them among the great positive evils of the world. They cause disease and premature death, and are very costly to our society. There is no loftier aim than to cure or prevent human infections with these viruses. The objective of much of the current research on herpesviruses is directed toward an understanding of the molecular mechanisms involved in initiation of infection, establish ment and termination of latent state, virus multiplication, and the destruction of cells which ultimately is the basis of the diseases caused by these viruses. At no time during the past 80 years, since members of the herpesvirus family were first discovered, has there been so much progress in our understanding of the biology of these viruses as in the past few years. Along with the development of a greater understanding of the molecular biol ogy of the well-known herpesviruses we have witnessed the isolation of new human herpes viruses.

The Herpesviruses

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Publisher : Springer Science & Business Media
ISBN 13 : 1461580218
Total Pages : 441 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis The Herpesviruses by : Carlos Lopez

Download or read book The Herpesviruses written by Carlos Lopez and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'You damn sadist/said mr cummings 'you try to make people think. ' -Ezra Pound (Canto 89) What makes herpesviruses unique? It is certainly not the size of their genomes or the individual features of their reproductive cycle, although in toto striking features that are exclusive to the herpesviruses abound. Unquestionably, the pre-eminent feature is the relationship of herpes viruses with their natural hosts. As described in preceding volumes, all herpesviruses seem to be able to colonize and to remain in a latent, nonproductive form for life of their hosts. Once established in the host, the relationship is best described as that of an armed truce. What happens when this truce breaks down or when the host encounters the virus for the first time is the subject of this volume. We have focused primarily on the five human herpesviruses [herpes simplex virus 1 (HSV-l), herpes simplex virus 2 (HSV-2), cytomegalovirus (CMV), varicella zoster virus (VZV) and Epstein-Barr virus (EBV)] because much more is known about them than about any other herpesviruses, and because it is of interest to compare both the diversity of manifestations of infections with human herpesviruses and the spectrum of human responses to these viruses. This volume summarizes the current knowledge of the pathogenesis and immunobiology of herpesvirus infections in man and describes new and developing approaches to prophylaxis and treatment. It contains con tributions from distinguished research scientists presently engaged at the forefront of these scientific investigations.

Herpes Simplex Virus

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Publisher : Springer Science & Business Media
ISBN 13 : 3642772471
Total Pages : 188 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Herpes Simplex Virus by : Barry T. Rouse

Download or read book Herpes Simplex Virus written by Barry T. Rouse and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although upstaged by the tragic appearance of the human immunodeficiency virus, herpes simplex viruses (HSV) types 1 and 2 continue to be major human pathogens against which we lack acceptable vaccines or other means of immunological control. The virus is large and complex, coding for 70 or more proteins. Although many mysteries remain to be unraveled, our knowledge base regarding genomic organization, gene expression and regulation, pathogenesis, and immune recog nition of component parts is quite considerable. Indeed, meet ings devoted entirely to herpesviruses are conspicuous by their frequency and excellent, yet sometimes exclusive, attendance. The purpose of this volume is to compile in a single book a series of reviews by leading investigators that deal with various aspects of virus-host interactions and which hopefully will pro vide clues as to how to best manage HSV from an immunobio logical perspective. Ultimately, one anticipates that a full under standing of virus-host interaction will lead to strategies useful for the prevention and control of HSV. The state of current progress with conventional vaccines is presented, as is a chapter on intracellular immunization. This latter novel approach to virus infections comes at approximately the bicentenary of Jenner's introduction of a successful conventional immunization strategy.

Human Herpesviruses

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Publisher : Cambridge University Press
ISBN 13 : 1139461648
Total Pages : 1325 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Human Herpesviruses by : Ann Arvin

Download or read book Human Herpesviruses written by Ann Arvin and published by Cambridge University Press. This book was released on 2007-08-16 with total page 1325 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.

IMMUNOBIOLOGY OF HERPES SIMPLEX VIRUS INFECTION

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Publisher : Springer
ISBN 13 :
Total Pages : 186 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis IMMUNOBIOLOGY OF HERPES SIMPLEX VIRUS INFECTION by : Rouse

Download or read book IMMUNOBIOLOGY OF HERPES SIMPLEX VIRUS INFECTION written by Rouse and published by Springer. This book was released on 1984-02-14 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Herpesviruses and Immunity

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Publisher : Springer Science & Business Media
ISBN 13 : 0306468085
Total Pages : 332 pages
Book Rating : 4.3/5 (64 download)

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Book Synopsis Herpesviruses and Immunity by : Peter G. Medveczky

Download or read book Herpesviruses and Immunity written by Peter G. Medveczky and published by Springer Science & Business Media. This book was released on 2006-04-11 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although virology and immunology are now considered separate disciplines, history shows that these areas ofinvestigation always overlapped and one cannot really exist without the other. This trend has become particularly significant and fruitful in the past few years in the area of herpesvirus research. The genomes of the most important herpesviruses have been sequenced, a significant portion of their genes have been identified, and many secrets of regulation of gene expr- sion have been unraveled. Now this progress sets the stage for a true revolution in herpesvirus research: analysis of interactions between the host and the virus. Because herpesviruses can induce, suppress, and fool the immune system, the most productive herpesvirologists are also expert immunologists, and the current results ofthis interdisciplinary effort are truly remarkable. Because herpesviruses cause many important human diseases, the devel- ment of vaccines against these agents is a very significant goal. This effort is also very challenging because of the complexity of herpesviruses and the lack of sufficient information about immune responses. The remarkable ability of herpesviruses to escape immune responses is - other feature that brings immunology and virology together. Herpesviruses - code many proteins that interact with and down-regulate some key elements of the immune system. Thisproperty of herpesviruses represents amajor challenge in developing strategies against these viruses. On the positive side, these viral proteins also provide novel tools for analyzing specific immune reactions and molecular mechanisms.

Human Herpesviruses

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Publisher : Springer
ISBN 13 : 9811072302
Total Pages : 498 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Human Herpesviruses by : Yasushi Kawaguchi

Download or read book Human Herpesviruses written by Yasushi Kawaguchi and published by Springer. This book was released on 2018-06-12 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces and reviews several topics for each human herpesvirus. One of the most important features of the book is that it covers aspects of both basic research and clinical medicine. Herpesviridae, a family of double-strand DNA viruses, has unique biological features by which these viruses establish latency after primary infection and reactivate in later life. Nine human herpesviruses are known so far, and each of them causes a variety of diseases in both primary infection and reactivation. Since the discovery of each human herpesvirus, an abundance of findings related to them has accumulated in basic research and clinical medicine. However, the vast majority of biological features is still masked in mystery. Furthermore, a strategy of treatment and prevention has not yet been established for most human herpesviruses. A wide range of readers will be interested in this volume with its treatment of problematic points and latest findings in the field.

Human Herpesvirus Infections

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Publisher :
ISBN 13 : 9780608034287
Total Pages : 318 pages
Book Rating : 4.0/5 (342 download)

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Book Synopsis Human Herpesvirus Infections by : Carlos Lopez

Download or read book Human Herpesvirus Infections written by Carlos Lopez and published by . This book was released on 1986-01-01 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Human Herpesvirus Infection

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Publisher : BoD – Books on Demand
ISBN 13 : 1838811583
Total Pages : 130 pages
Book Rating : 4.8/5 (388 download)

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Book Synopsis Human Herpesvirus Infection by : Ronaldo Luis Thomasini

Download or read book Human Herpesvirus Infection written by Ronaldo Luis Thomasini and published by BoD – Books on Demand. This book was released on 2020-04-01 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: The relationship between herpesviruses and humans probably dates from thousands of years ago. In the last few decades, many aspects of herpesvirus infections have been understood, such as infections with a range of manifestations (severe, mild, or subclinical). Herpesvirus can remain latent during a lifetime and sometimes their reactivation can cause different clinical features in the patient. Several conditions have been related to herpesvirus reactivation such as complications in transplant organ recipients and immune regulatory modification in the elderly. Aspects of human herpesvirus simples, varicella-zoster virus, and cytomegalovirus are presented and discussed in this book.

Immunology of Human Herpesvirus Infections

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (497 download)

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Book Synopsis Immunology of Human Herpesvirus Infections by : Royal Society of Medicine (Great Britain)

Download or read book Immunology of Human Herpesvirus Infections written by Royal Society of Medicine (Great Britain) and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Immunobiology of Infection with Herpes Simplex Virus

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Publisher : S Karger Ag
ISBN 13 : 9783805535175
Total Pages : 0 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Immunobiology of Infection with Herpes Simplex Virus by : Holger Kirchner

Download or read book Immunobiology of Infection with Herpes Simplex Virus written by Holger Kirchner and published by S Karger Ag. This book was released on 1982 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Human Herpesvirus-6

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Publisher : Elsevier
ISBN 13 : 008046128X
Total Pages : 393 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Human Herpesvirus-6 by :

Download or read book Human Herpesvirus-6 written by and published by Elsevier. This book was released on 2006-07-04 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present book presents a comprehensive review of Human Herpesvirus-6 (HHV-6) infects up to 90% of the world’s population and can cause potentially life-threatening diseases. Clinicians typically do not search for HHV-6, and if they do, they will find only few laboratories providing the necessary diagnostic tests that can differentiate between active and latent infection. Adding to this problem is that scientists still disagree about whether serological or molecular assays will be the best diagnostic test, yet there is no disagreement about the inadequacy of many of the currently existing assays. Consequently, our knowledge of etiology and pathogenesis of HHV-6 associated diseases can only come from the combined efforts of clinicians, virologists, molecular biologists and pathologists. It is the prime task of this book to summarize the status quo of HHV-6 research and to further stimulate such a collaboration. It will be a valuable reference for both clinical and basic scientists including epidemiologists, virologists, practicing clinicians and infectiologists, pathologists and essentially all scientists entering the field of herpes virus research.

Human Herpesviruses HHV-6A, HHV-6B and HHV-7

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Publisher : Elsevier
ISBN 13 : 0444627162
Total Pages : 362 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Human Herpesviruses HHV-6A, HHV-6B and HHV-7 by : Louis Flamand

Download or read book Human Herpesviruses HHV-6A, HHV-6B and HHV-7 written by Louis Flamand and published by Elsevier. This book was released on 2014-02-11 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised and updated, Human Herpesviruses HHV-6A, HHV-6B & HHV-7, Third Edition, delivers a contemporary and thorough review of HHV-6, beginning with foundational explorations of classification, molecular biology, and chromosomal integration of the virus, through to clinical details, including pathologic features of infection, and clinical effects on various organ systems. The work now includes coverage of HHV-7, a virus that remains underestimated in transplant reactivation, seizures, and encephalitis. The book examines the role of HHV-6 in myriad diseases, including cognitive disorders following bone marrow transplant, mesial temporal lobe epilepsy, multiple sclerosis, autoimmune disease, encephalitis, Hodgkin's disease lymphoma (HHV-6B), and glioma (HHV-6A). Descriptions of current and novel molecular and serological diagnostic assays, along with detailed protocols, are included to aid researchers and clinicians in discriminating potential false positives originating from chromosomally integrated HHV-6, and in differentiating between active and latent infection. Human Herpesviruses HHV-6A, HHV-6B & HHV-7, Third Edition is a valuable reference for both clinical and basic scientists, including epidemiologists, virologists, practicing clinicians, infectious disease specialists, pathologists, and all scientists entering the field of herpes virus research. The work is a practical and thorough resource for a foundational understanding of HHV-6 and HHV-7, while providing a cutting-edge translational and clinical reference to those looking to understand and diagnose associated viral diseases. Delivers the latest molecular diagnostic tests, the present-day gold standard for monitoring HHV-6 Provides expert analysis of T-cell immune response against HHV-6 Presents tools for differential diagnosis in HHV-6 viral infections Includes new information on the previously-largely-unknown biological consequences of ciHHV-6 Offers coverage of new discoveries relating to HHV-7

The Herpesviruses

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Publisher : Springer Science & Business Media
ISBN 13 : 1461323835
Total Pages : 428 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis The Herpesviruses by : Bernard Roizman

Download or read book The Herpesviruses written by Bernard Roizman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: A great truth is a truth whose opposite. is also a great truth. Thomas Mann (Essay on Freud, 1937) This volume centers on pseudorabies (PR V), herpes simplex viruses 1 and 2 (HSV-1 and HSV-2), and human cytomegalovirus (CMV) and fulfills three objectives. The chapters on the epidemiology and latency of HSV, and on the glycoproteins specified by HSV and CMV, set the stage for the discussions of the immunobiology and pathogenesis of human herpesvirus infections in Volume 4. The epidemiology of HSV is the basis of our understanding of the spread and survival of this virus in the human populations. Central to the epidemiology of HSV and its pathogenesis in humans is the ability of the virus to remain in a latent state for the life of its host. The viral membrane glycoproteins are among the most interesting virion proteins, primarily because of their critical role in the initiation of infection. Since they are the surface membrane proteins of the virion and appear on the surface of productively infected cells, they are also the obvious if not the exclusive targets of the immune response. The chapters on the transforming potential of HSV and CMV, and on the role of HSV in human cancer, deal with challenging problems requiring rather different experimental tools.

The Interplay Between Innate Immunity And Herpesviruses

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889717828
Total Pages : 230 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis The Interplay Between Innate Immunity And Herpesviruses by : Santo Landolfo

Download or read book The Interplay Between Innate Immunity And Herpesviruses written by Santo Landolfo and published by Frontiers Media SA. This book was released on 2021-12-03 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Herpesviruses

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Publisher : Springer
ISBN 13 : 9781461323846
Total Pages : 432 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis The Herpesviruses by : Bernard Roizman

Download or read book The Herpesviruses written by Bernard Roizman and published by Springer. This book was released on 2012-01-19 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: A great truth is a truth whose opposite. is also a great truth. Thomas Mann (Essay on Freud, 1937) This volume centers on pseudorabies (PR V), herpes simplex viruses 1 and 2 (HSV-1 and HSV-2), and human cytomegalovirus (CMV) and fulfills three objectives. The chapters on the epidemiology and latency of HSV, and on the glycoproteins specified by HSV and CMV, set the stage for the discussions of the immunobiology and pathogenesis of human herpesvirus infections in Volume 4. The epidemiology of HSV is the basis of our understanding of the spread and survival of this virus in the human populations. Central to the epidemiology of HSV and its pathogenesis in humans is the ability of the virus to remain in a latent state for the life of its host. The viral membrane glycoproteins are among the most interesting virion proteins, primarily because of their critical role in the initiation of infection. Since they are the surface membrane proteins of the virion and appear on the surface of productively infected cells, they are also the obvious if not the exclusive targets of the immune response. The chapters on the transforming potential of HSV and CMV, and on the role of HSV in human cancer, deal with challenging problems requiring rather different experimental tools.

Human Herpesvirus Infections

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Author :
Publisher : Lippincott Williams & Wilkins
ISBN 13 :
Total Pages : 328 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Human Herpesvirus Infections by : Carlos Lopez

Download or read book Human Herpesvirus Infections written by Carlos Lopez and published by Lippincott Williams & Wilkins. This book was released on 1986 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: